set -e; # Alert user to any uncaught error ulimit -c unlimited STARTWD=$(pwd); TOOL_PASSES=""; TOOL_FAILURES=""; for tool in $(ls); do [ -d "${STARTWD}/${tool}" ] || continue; echo "Testing bedtools $tool:"; cd "${STARTWD}/${tool}"; bash "test-${tool}.sh" \ && TOOL_PASSES="$TOOL_PASSES $tool" \ || TOOL_FAILURES="$TOOL_FAILURES $tool"; done echo echo echo "--------------------------" echo " Test Results " echo "--------------------------" echo "Tools passing: $TOOL_PASSES" echo "Tools failing: $TOOL_FAILURES" echo "NB: the 'negativecontrol' test is supposed to fail. If it wasn't caught, " echo "something went wrong with this test script." [ "$TOOL_FAILURES" = " negativecontrol" ] || exit 1; chr1 10 20 345.7 why? 11 chr1 249250621 chr2 243199373 chr3 198022430 chr4 191154276 chr5 180915260 chr6 171115067 chr7 159138663 chr8 146364022 chr9 141213431 chr10 135534747 chr11 135006516 chr12 133851895 chr13 115169878 chr14 107349540 chr15 102531392 chr16 90354753 chr17 81195210 chr18 78077248 chr19 59128983 chr20 63025520 chr21 48129895 chr22 51304566 chrX 155270560 chrY 59373566 chrM 16571 chr1_gl000191_random 106433 chr1_gl000192_random 547496 chr4_ctg9_hap1 590426 chr4_gl000193_random 189789 chr4_gl000194_random 191469 chr6_apd_hap1 4622290 chr6_cox_hap2 4795371 chr6_dbb_hap3 4610396 chr6_mann_hap4 4683263 chr6_mcf_hap5 4833398 chr6_qbl_hap6 4611984 chr6_ssto_hap7 4928567 chr7_gl000195_random 182896 chr8_gl000196_random 38914 chr8_gl000197_random 37175 chr9_gl000198_random 90085 chr9_gl000199_random 169874 chr9_gl000200_random 187035 chr9_gl000201_random 36148 chr11_gl000202_random 40103 chr17_ctg5_hap1 1680828 chr17_gl000203_random 37498 chr17_gl000204_random 81310 chr17_gl000205_random 174588 chr17_gl000206_random 41001 chr18_gl000207_random 4262 chr19_gl000208_random 92689 chr19_gl000209_random 159169 chr21_gl000210_random 27682 chrUn_gl000211 166566 chrUn_gl000212 186858 chrUn_gl000213 164239 chrUn_gl000214 137718 chrUn_gl000215 172545 chrUn_gl000216 172294 chrUn_gl000217 172149 chrUn_gl000218 161147 chrUn_gl000219 179198 chrUn_gl000220 161802 chrUn_gl000221 155397 chrUn_gl000222 186861 chrUn_gl000223 180455 chrUn_gl000224 179693 chrUn_gl000225 211173 chrUn_gl000226 15008 chrUn_gl000227 128374 chrUn_gl000228 129120 chrUn_gl000229 19913 chrUn_gl000230 43691 chrUn_gl000231 27386 chrUn_gl000232 40652 chrUn_gl000233 45941 chrUn_gl000234 40531 chrUn_gl000235 34474 chrUn_gl000236 41934 chrUn_gl000237 45867 chrUn_gl000238 39939 chrUn_gl000239 33824 chrUn_gl000240 41933 chrUn_gl000241 42152 chrUn_gl000242 43523 chrUn_gl000243 43341 chrUn_gl000244 39929 chrUn_gl000245 36651 chrUn_gl000246 38154 chrUn_gl000247 36422 chrUn_gl000248 39786 chrUn_gl000249 38502 chr1 20 30 b1 1 + chr1 90 101 b2 2 - chr1 100 110 b3 3 + chr1 200 210 b4 4 + ##fileformat=VCFv4.0 #CHROM POS ID REF ALT QUAL FILTER INFO chr1 1 . G C . . 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L^:4zfS;Z;Lg٭a꒘9&.˄r_Wr|!19 v8F+Q[8`K,܁#˵P_/H6㖇p`Hyr5C=#lu;pr녹|*NNYbH![?sK+t.,ƉI] ]j| O|)ct BPJX#'qe)+Wpu!tFܶ}<敘}ȸc,ˍ8Aj~3-BWFu/LýOɇت [w\eA8/UKp\Ǥ!J"ݢ 7= 0@|굤{.K4gNP{qE64-Dӥ<s.<\J^p 8y.yHY҆V Nx =yJKUSRk<\cty^<\jnKy^+y^s{kʸ\A͸*#ƭMqL. 66qt9EwU"3]0nzC+eq+WQ7!ow_F*tzE~{m;?jL}`z߆yNLogSˣz]z՟wrvUysu>W!F2V߁k8>W~js{|m+s]_7sU ~.>2smWxji|Nk|nq]Gy1Y.8cs됛@|))9س}Qi99D4y溙l'g\vrL%8#6{cpnK5^`RmR [*K0bxjOZmҟQK*vK(e{^ГfCy=^h^3UZ^r@bm!k"r?W d&P!ZHA kq-] 7T2%Pр-4u"^!TP*BTLwۓle?T~@HW ~-^sWY$tl2Of#r|w_/Fzݻ0FHY9"F/m,|M X,s6u,Js_/7t,v 1׿]k]1½R߲|ue(j/">D6dA%%z-[,.. "RCE$(,+&qE.b*YN"L"<_IHN/=] YQ"&f g?!X vA?2\0`~zBZ`|j-xu~|o<`0AtoNVMtE2ME*ݪq0;&yCy Dt3T>dneۘl46uA\0[mj5^j+#MN5{{m;гLQ"e߈ZfcC? 򆡰؋,rWʦAׁԜ1'Y#pAJxɫ_ROR'NnBCchr1 0 100 exon1 1 + chr1 200 300 exon2 2 - chr1 11323785 11617177 chr1 12645605 13926923 chr1 14750216 15119039 1 100 200 b1 bxchr17 7577068 7577157BC8K(24442L28!" !.,&BCchr1 5 15 @HD VN:1.0 GO:none SO:coordinate @SQ SN:chr1 LN:249250621 mapped 16 chr1 1 40 30M * 0 0 GAAGGCCACCGCCGCGGTTATTTTCCTTCA CCCDDB?=FJIIJIGFJIJHIJJJJJJJJI MD:Z:50 umapped 4 * 1 40 30M * 0 0 GAAGGCCACCGCCGCGGTTATTTTCCTTCA CCCDDB?=FJIIJIGFJIJHIJJJJJJJJI MD:Z:50 chr1 0 100 c1 1 + ##fileformat=VCFv4.1 chr1 1 a G 70.90 . TOOL=LUMPY;SVTYPE=DEL;SVLEN=-389,-4611;END=253195;STR=+-:4;IMPRECISE;CIPOS=-2,137;CIEND=0,0;EVENT=791255;SUP=4;PESUP=4;SRSUP=0;EV=PE;PRIN;CSQ=intergenic_variant|||||||||| chr1 4 a G 70.90 . TOOL=LUMPY;SVTYPE=DEL;END=253195;STR=+-:4;IMPRECISE;CIPOS=-2,137;CIEND=0,0;EVENT=791255;SUP=4;PESUP=4;SRSUP=0;EV=PE;PRIN;CSQ=intergenic_variant||||||||||;SVLEN=-10chr01 15 25 CRAMa.cramML7uOo8{؋)MQ4k׮O4=lHS)NBҎ~Y9޼<`?>||G"h,,Ye9-l\X:lZ)}ƅ"F֓,nc~VZ0-8BKUM\?A V%7aǷ-> zĪ}l\,F_I2s,3+T 포l ><ƿ6 ߂ ғװ$?'3}c3+ѬV]t(RTn';4 Y0l@w Kk) ]Z%#'Fjʜ ֐hޏ1봅I)T_6/qGϯ.I:89v$Bq?8!7vhC,9ph =,8:ī[CT;LYZ:3<;P܂Ox^Ci0ܜNgab 8|ԩ!>ohDcWJ[ݼë2TߣjQ4KE !D4l[7/ds9n2CIX/k5@d|!6؄qmojF)MWDHt7MMNsZ"|q'TDPGZAMCSMCMQCPQCUQCASCSMRNAPuBFCFRLdAPRGNFTLFNFCFPBSIN BB*%MQRN QS RISCxASC ASCPQC PQCSMC SMCAMC AMCMQC MQCPGZ PGZUQC UQCwp:DD ASCPQCSMCAMCMQCPGZUQC,ƻjrPsiq;dZd/ 6>ssv66rt222442160206Tfp/ ->\E j0 P4^L:,ɖ .}OU˿%VD V,\@0"L/v_4iKI蠓e,"ZYoFgΏNG~ݘJ9Rw7ړJ mnxwk|~n Ol Ur=GssttfuK VKn Ui<ce,֩Kmcev9cw -NDc  8  cdgazx& %F c&Z @G"ASCc8c4UHPQC}w21SMCcrؔPєGAMCcbQ{ͣMQCc`Aq{PGZ!/OLcC0߇qwUQCc8c4{}*bEOFOcK##fileformat=VCFv4.1 ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##UnifiedGenotyper="analysis_type=UnifiedGenotyper input_file=[bam/all.conc.on.pos.dedup.realigned.bam] read_buffer_size=null phone_home=STANDARD read_filter=[] intervals=null excludeIntervals=null interval_set_rule=UNION interval_merging=ALL reference_sequence=/home/arq5x/cphg-home/shared/genomes/hg19/bwa/gatk/hg19_gatk.fa rodBind=[] nonDeterministicRandomSeed=false downsampling_type=BY_SAMPLE downsample_to_fraction=null downsample_to_coverage=250 baq=OFF baqGapOpenPenalty=40.0 performanceLog=null useOriginalQualities=false defaultBaseQualities=-1 validation_strictness=SILENT unsafe=null num_threads=10 num_cpu_threads=null num_io_threads=null num_bam_file_handles=null read_group_black_list=null pedigree=[] pedigreeString=[] pedigreeValidationType=STRICT allow_intervals_with_unindexed_bam=false logging_level=INFO log_to_file=null help=false genotype_likelihoods_model=BOTH p_nonref_model=EXACT heterozygosity=0.0010 pcr_error_rate=1.0E-4 genotyping_mode=DISCOVERY output_mode=EMIT_VARIANTS_ONLY standard_min_confidence_threshold_for_calling=30.0 standard_min_confidence_threshold_for_emitting=30.0 computeSLOD=false alleles=(RodBinding name= source=UNBOUND) min_base_quality_score=17 max_deletion_fraction=0.05 multiallelic=false max_alternate_alleles=5 min_indel_count_for_genotyping=5 indel_heterozygosity=1.25E-4 indelGapContinuationPenalty=10.0 indelGapOpenPenalty=45.0 indelHaplotypeSize=80 bandedIndel=false indelDebug=false ignoreSNPAlleles=false dbsnp=(RodBinding name= source=UNBOUND) out=org.broadinstitute.sting.gatk.io.stubs.VCFWriterStub NO_HEADER=org.broadinstitute.sting.gatk.io.stubs.VCFWriterStub sites_only=org.broadinstitute.sting.gatk.io.stubs.VCFWriterStub debug_file=null metrics_file=null annotation=[] excludeAnnotation=[] filter_mismatching_base_and_quals=false" ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##reference=file:///home/arq5x/cphg-home/shared/genomes/hg19/bwa/gatk/hg19_gatk.fa ##SnpEffVersion="SnpEff 3.0g (build 2012-08-31), by Pablo Cingolani" ##SnpEffCmd="SnpEff -i vcf -o vcf GRCh37.66 /home/udp3f/cphg-home/projects/rs-exome/varCalling/2012-Feb-01/all.raw.nobaq.vcf " ##INFO= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT 1094PC0005 1094PC0009 1094PC0012 1094PC0013 chr1 1 789 chr1 882 1033 chr1 1034 1369 chr1 18746 18972 1 100 200 a1 ax 1 300 400 a2 ay 1 400 500 a3 az 2 500 600 a4 aq chr2L 50 100 1 1000000000 1000000005 1 10000000000 10000000005 1 30000000000 30000000005 chr1 9550913 9551859 b.C.1 0 - chr1 9550913 9621173 b 1 - chr1 9551859 9553903 b.I.1 0 - chr1 9553903 9553952 b.C.2 0 - chr1 9553952 9609630 b.I.2 0 - chr1 9602747 9603392 f.I.1 0 + chr1 9603392 9603555 f.C.2 0 + chr1 9603392 9603555 g.C.3 0 + chr1 9603555 9609916 f.I.2 0 + chr1 9603555 9609916 g.I.3 0 + BCOˋD}QAA$ɯy 3@'+HԤ3tGśgEmX]Izaې|Uܯ7;ЎT󼌒,`6 mxp]b51hŶ&cFX BLV-s8w$U$1BmhiZ Ԇ78 q}ױ4MPQ%4MWm\0j3&8.ðKvLtv\GM OG,3 &e:ͮ0llk49el!Kh;sm.ir´kaZGto_eiX exp $BT intersect -a a.bed -b b.bed > obs check obs exp rm obs exp ########################################################### # Test intersection of a as bed from redirect vs b as bed from file ############################################################ echo -e " intersect.new.t02...\c" echo \ "chr1 100 101 a2 2 - chr1 100 110 a2 2 -" > exp $BT intersect -a - -b b.bed < a.bed > obs check obs exp rm obs exp ########################################################### # Test intersection of a as bed from pipe vs b as bed from file ############################################################ echo -e " intersect.new.t03...\c" echo \ "chr1 100 101 a2 2 - chr1 100 110 a2 2 -" > exp cat a.bed | $BT intersect -a - -b b.bed > obs check obs exp rm obs exp ########################################################### # Test intersection of a as bed from fifo vs b as bed from file ############################################################ echo -e " intersect.new.t04...\c" echo \ "chr1 100 101 a2 2 - chr1 100 110 a2 2 -" > exp $BT intersect -a <(cat a.bed) -b b.bed > obs check obs exp rm obs exp ########################################################### # Test intersection of a as gzipped from file vs b as bed from file ############################################################ echo -e " intersect.new.t05...\c" echo \ "chr1 100 101 a2 2 - chr1 100 110 a2 2 -" > exp $BT intersect -a a_gzipped.bed.gz -b b.bed > obs check obs exp rm obs exp ########################################################### # Test intersection of a as gzipped from redirect vs b as bed from file ############################################################ echo -e " intersect.new.t06...\c" echo \ "chr1 100 101 a2 2 - chr1 100 110 a2 2 -" > exp $BT intersect -a - -b b.bed < a_gzipped.bed.gz > obs check obs exp rm obs exp ########################################################### # Test intersection of a as gzipped from pipe vs b as bed from file ############################################################ echo -e " intersect.new.t07...\c" echo \ "chr1 100 101 a2 2 - chr1 100 110 a2 2 -" > exp cat a_gzipped.bed.gz | $BT intersect -a - -b b.bed > obs check obs exp rm obs exp ########################################################### # Test intersection of a as gzipped from fifo vs b as bed from file ############################################################ echo -e " intersect.new.t08...\c" echo \ "chr1 100 101 a2 2 - chr1 100 110 a2 2 -" > exp $BT intersect -a <(cat a_gzipped.bed.gz) -b b.bed > obs check obs exp rm obs exp ########################################################### # Test intersection of a as bgzipped from file vs b as bed from file ############################################################ echo -e " intersect.new.t09...\c" echo \ "chr1 100 101 a2 2 - chr1 100 110 a2 2 -" > exp $BT intersect -a a_bgzipped.bed.gz -b b.bed > obs check obs exp rm obs exp ########################################################### # Test intersection of a as bgzipped from redirect vs b as bed from file ############################################################ echo -e " intersect.new.t10...\c" echo \ "chr1 100 101 a2 2 - chr1 100 110 a2 2 -" > exp $BT intersect -a - -b b.bed < a_bgzipped.bed.gz > obs check obs exp rm obs exp ########################################################### # Test intersection of a as bgzipped from pipe vs b as bed from file ############################################################ echo -e " intersect.new.t11...\c" echo \ "chr1 100 101 a2 2 - chr1 100 110 a2 2 -" > exp cat a_bgzipped.bed.gz | $BT intersect -a - -b b.bed > obs check obs exp rm obs exp ########################################################### # Test intersection of a as bgzipped from fifo vs b as bed from file ############################################################ echo -e " intersect.new.t12...\c" echo \ "chr1 100 101 a2 2 - chr1 100 110 a2 2 -" > exp $BT intersect -a <(cat a_bgzipped.bed.gz) -b b.bed > obs check obs exp rm obs exp ########################################################### # Test intersection of a as bam from file vs b as bed from file ############################################################ echo -e " intersect.new.t13...\c" $BT intersect -a a.bam -b b.bed> obs bam_check obs aVSb.bam rm obs ########################################################### # Test intersection of a as bam from redirect vs b as bed from file ############################################################ echo -e " intersect.new.t14...\c" $BT intersect -a - -b b.bed < a.bam> obs bam_check obs aVSb.bam rm obs ########################################################### # Test intersection of a as bam from pipe vs b as bed from file ############################################################ echo -e " intersect.new.t15...\c" cat a.bam | $BT intersect -a - -b b.bed> obs bam_check obs aVSb.bam rm obs ########################################################### # Test intersection of a as bam from fifo vs b as bed from file ############################################################ echo -e " intersect.new.t16...\c" $BT intersect -a <(cat a.bam) -b b.bed > obs bam_check obs aVSb.bam rm obs ########################################################### # Test intersection of bam file containing both good reads # and those where both read and mate are unmapped vs b file # as bed. ############################################################ echo -e " intersect.new.t17...\c" echo \ "chr1 100 101 a2 255 - 100 200 0,0,0 1 100, 0, chr1 100 110 a2 255 - 100 200 0,0,0 1 100, 0," > exp $BT intersect -a a_with_bothUnmapped.bam -b b.bed -bed > obs check obs exp rm obs exp ########################################################### # Test intersection of bam file containing both good reads # and those where both read and mate are unmapped vs b file # as bed, with noHit (-v) option. ############################################################ echo -e " intersect.new.t18...\c" echo \ "chr1 10 20 a1 255 + 10 20 0,0,0 1 10, 0, . -1 -1 FCC1MK2ACXX:1:1101:5780:51632#/1 0 . -1 -1 -1 0,0,0 0 . . . -1 -1 FCC1MK2ACXX:1:1101:5780:51632#/2 0 . -1 -1 -1 0,0,0 0 . . . -1 -1 FCC1MK2ACXX:1:1101:8137:99409#/1 0 . -1 -1 -1 0,0,0 0 . . . -1 -1 FCC1MK2ACXX:1:1101:8137:99409#/2 0 . -1 -1 -1 0,0,0 0 . . . -1 -1 FCC1MK2ACXX:1:1102:6799:2633#/1 0 . -1 -1 -1 0,0,0 0 . . . -1 -1 FCC1MK2ACXX:1:1102:6799:2633#/2 0 . -1 -1 -1 0,0,0 0 . ." > exp $BT intersect -a a_with_bothUnmapped.bam -b b.bed -bed -v > obs check obs exp rm obs exp ########################################################### # Test intersection of bam file containing read where query # is mapped and mate is not. ############################################################ echo -e " intersect.new.t19...\c" echo \ "chr1 98650 98704 FCC1MK2ACXX:1:1212:13841:9775#/1 0 + 98604 98704 0,0,0 1 100, 0," > exp $BT intersect -a oneUnmapped.bam -b j1.bed -bed > obs check obs exp rm obs exp ########################################################### # Test intersection of bam file containing read where query # is mapped and mate is not, with noHit (-v) option. ############################################################ echo -e " intersect.new.t20...\c" echo \ "chr1 -1 -1 FCC1MK2ACXX:1:1212:13841:9775#/2 0 . -1 -1 -1 0,0,0 0 . ." > exp $BT intersect -a oneUnmapped.bam -b j1.bed -bed -v > obs check obs exp rm obs exp ########################################################### # Test intersection of bam file containing read where query # is unmapped but mate is mapped. ############################################################ echo -e " intersect.new.t20.b...\c" touch exp $BT intersect -a queryUnmappedMateMappedCoordsInvalid.bam -b j1.bed -bed > obs check obs exp rm obs exp ########################################################### # Test intersection of bam file containing read where one # mate is mapped and one is not, with noHit (-v) option. ############################################################ echo -e " intersect.new.t20.c...\c" echo ". -1 -1 TTTACCTTT:4FSQ5P1:286:D2GA7ACXX:6:2316:20858:89646 0 . -1 -1 -1 0,0,0 0 . ." > exp $BT intersect -a queryUnmappedMateMappedCoordsInvalid.bam -b j1.bed -bed -v > obs check obs exp rm obs exp ########################################################### # Test intersection with -sorted, see that order specified # in genome file is enforced. ############################################################ echo -e " intersect.new.t21...\c" echo \ "Error: Sorted input specified, but the file chromOrderA.bed has the following record with a different sort order than the genomeFile human.hg19.genome chr10 10 20 a3 100 +" > exp $BT intersect -a chromOrderA.bed -b chromOrderB.bed -sorted -g human.hg19.genome 2>obs check obs exp rm obs exp ########################################################### # Test intersection with -sorted, see that chrom order # change is ok as long as query and db have same order. ############################################################ echo -e " intersect.new.t22...\c" echo \ "chr1 15 20 a1 100 + chr2 15 20 a2 100 + chr10 15 20 a3 100 + chr11 15 20 a4 100 + chrX 15 20 a5 100 + chrM 15 20 a6 100 +" > exp $BT intersect -a chromOrderA.bed -b chromOrderB.bed -sorted > obs check obs exp rm obs exp ########################################################### # Test intersection with -sorted, see that hits are correct # when sort order of files matches genome file sort order ############################################################ echo -e " intersect.new.t23...\c" echo \ "chr1 15 20 a1 100 + chr2 15 20 a2 100 + chr10 15 20 a3 100 + chr11 15 20 a4 100 + chrX 15 20 a5 100 + chrM 15 20 a6 100 +" > exp $BT intersect -a chromOrderA.bed -b chromOrderB.bed -sorted -g human.hg19.vSort.genome > obs check obs exp rm obs exp ########################################################### # Test intersection of a with large header as bed from file vs b as bed from file ############################################################ echo -e " intersect.new.t24...\c" echo \ "chr1 100 101 a2 2 - chr1 100 110 a2 2 -" > exp $BT intersect -a a_withLargeHeader.bed -b b.bed > obs check obs exp rm obs exp ########################################################### # Test intersection of a with large header as bed from redirect vs b as bed from file ############################################################ echo -e " intersect.new.t25...\c" echo \ "chr1 100 101 a2 2 - chr1 100 110 a2 2 -" > exp $BT intersect -a - -b b.bed < a_withLargeHeader.bed > obs check obs exp rm obs exp ########################################################### # Test intersection of a with large header as bed from pipe vs b as bed from file ############################################################ echo -e " intersect.new.t26...\c" echo \ "chr1 100 101 a2 2 - chr1 100 110 a2 2 -" > exp cat a_withLargeHeader.bed | $BT intersect -a - -b b.bed > obs check obs exp rm obs exp ########################################################### # Test intersection of a with large header as bed from fifo vs b as bed from file ############################################################ echo -e " intersect.new.t27...\c" echo \ "chr1 100 101 a2 2 - chr1 100 110 a2 2 -" > exp $BT intersect -a <(cat a_withLargeHeader.bed) -b b.bed > obs check obs exp rm obs exp ########################################################### # Test intersection of a with large header as gzipped from file vs b as bed from file ############################################################ echo -e " intersect.new.t28...\c" echo \ "chr1 100 101 a2 2 - chr1 100 110 a2 2 -" > exp $BT intersect -a a_withLargeHeader_gzipped.bed.gz -b b.bed > obs check obs exp rm obs exp ########################################################### # Test intersection of a with large header as gzipped from redirect vs b as bed from file ############################################################ echo -e " intersect.new.t29...\c" echo \ "chr1 100 101 a2 2 - chr1 100 110 a2 2 -" > exp $BT intersect -a - -b b.bed < a_withLargeHeader_gzipped.bed.gz > obs check obs exp rm obs exp ########################################################### # Test intersection of a with large header as gzipped from pipe vs b as bed from file ############################################################ echo -e " intersect.new.t30...\c" echo \ "chr1 100 101 a2 2 - chr1 100 110 a2 2 -" > exp cat a_withLargeHeader_gzipped.bed.gz | $BT intersect -a - -b b.bed > obs check obs exp rm obs exp ########################################################### # Test intersection of a with large header as gzipped from fifo vs b as bed from file ############################################################ echo -e " intersect.new.t31...\c" echo \ "chr1 100 101 a2 2 - chr1 100 110 a2 2 -" > exp $BT intersect -a <(cat a_withLargeHeader_gzipped.bed.gz) -b b.bed > obs check obs exp rm obs exp ########################################################### # Test intersection of a with large header as bgzipped from file vs b as bed from file ############################################################ echo -e " intersect.new.t32...\c" echo \ "chr1 100 101 a2 2 - chr1 100 110 a2 2 -" > exp $BT intersect -a a_withLargeHeader_bgzipped.bed.gz -b b.bed > obs check obs exp rm obs exp ########################################################### # Test intersection of a with large header as bgzipped from redirect vs b as bed from file ############################################################ echo -e " intersect.new.t33...\c" echo \ "chr1 100 101 a2 2 - chr1 100 110 a2 2 -" > exp $BT intersect -a - -b b.bed < a_withLargeHeader_bgzipped.bed.gz > obs check obs exp rm obs exp ########################################################### # Test intersection of a with large header as bgzipped from pipe vs b as bed from file ############################################################ echo -e " intersect.new.t34...\c" echo \ "chr1 100 101 a2 2 - chr1 100 110 a2 2 -" > exp cat a_withLargeHeader_bgzipped.bed.gz | $BT intersect -a - -b b.bed > obs check obs exp rm obs exp ########################################################### # Test intersection of a with large header as bgzipped from fifo vs b as bed from file ############################################################ echo -e " intersect.new.t35...\c" echo \ "chr1 100 101 a2 2 - chr1 100 110 a2 2 -" > exp $BT intersect -a <(cat a_withLargeHeader_bgzipped.bed.gz) -b b.bed > obs check obs exp rm obs exp ########################################################### # Test intersection of a with large header as bed from file # vs b as bed from file, and print header ############################################################ echo -e " intersect.new.t36...\c" $BT intersect -a a_withLargeHeader.bed -b b.bed -header > obs check obs aWithHeaderVsB.txt rm obs ########################################################### # Test intersection of a with large header as bed from # redirect vs b as bed from file, and print header ############################################################ echo -e " intersect.new.t37...\c" $BT intersect -a - -b b.bed < a_withLargeHeader.bed -header > obs check obs aWithHeaderVsB.txt rm obs ########################################################### # Test intersection of a with large header as bed from pipe # vs b as bed from file, and print header ############################################################ echo -e " intersect.new.t38...\c" cat a_withLargeHeader.bed | $BT intersect -a - -b b.bed -header > obs check obs aWithHeaderVsB.txt rm obs ########################################################### # Test intersection of a with large header as bed from fifo # vs b as bed from file, and print header ############################################################ echo -e " intersect.new.t39...\c" $BT intersect -a <(cat a_withLargeHeader.bed) -b b.bed -header > obs check obs aWithHeaderVsB.txt rm obs ########################################################### # Test intersection of a with large header as gzipped from # file vs b as bed from file, and print header ############################################################ echo -e " intersect.new.t40...\c" $BT intersect -a a_withLargeHeader_gzipped.bed.gz -b b.bed -header > obs check obs aWithHeaderVsB.txt rm obs ########################################################### # Test intersection of a with large header as gzipped from # redirect vs b as bed from file, and print header ############################################################ echo -e " intersect.new.t41...\c" $BT intersect -a - -b b.bed < a_withLargeHeader_gzipped.bed.gz -header > obs check obs aWithHeaderVsB.txt rm obs ########################################################### # Test intersection of a with large header as gzipped from # pipe vs b as bed from file, and print header ############################################################ echo -e " intersect.new.t42...\c" cat a_withLargeHeader_gzipped.bed.gz | $BT intersect -a - -b b.bed -header > obs check obs aWithHeaderVsB.txt rm obs ########################################################### # Test intersection of a with large header as gzipped from # fifo vs b as bed from file, and print header ############################################################ echo -e " intersect.new.t43...\c" $BT intersect -a <(cat a_withLargeHeader_gzipped.bed.gz) -b b.bed -header > obs check obs aWithHeaderVsB.txt rm obs ########################################################### # Test intersection of a with large header as bgzipped from # file vs b as bed from file, and print header ############################################################ echo -e " intersect.new.t44...\c" $BT intersect -a a_withLargeHeader_bgzipped.bed.gz -b b.bed -header > obs check obs aWithHeaderVsB.txt rm obs ########################################################### # Test intersection of a with large header as bgzipped from # redirect vs b as bed from file, and print header ############################################################ echo -e " intersect.new.t45...\c" $BT intersect -a - -b b.bed < a_withLargeHeader_bgzipped.bed.gz -header > obs check obs aWithHeaderVsB.txt rm obs ########################################################### # Test intersection of a with large header as bgzipped from # pipe vs b as bed from file, and print header ############################################################ echo -e " intersect.new.t46...\c" cat a_withLargeHeader_bgzipped.bed.gz | $BT intersect -a - -b b.bed -header > obs check obs aWithHeaderVsB.txt rm obs ########################################################### # Test intersection of a with large header as bgzipped from # fifo vs b as bed from file, and print header ############################################################ echo -e " intersect.new.t47...\c" $BT intersect -a <(cat a_withLargeHeader_bgzipped.bed.gz) -b b.bed -header > obs check obs aWithHeaderVsB.txt rm obs ########################################################### # Test enforcement of sort order when using -sorted option. # Show that detect chrom "jumping", i.e. chr1, chr2, then # back to chr1 ############################################################ echo -e " intersect.new.t48...\c" echo "Error: Sorted input specified" > exp $BT intersect -a chromsOutOfOrder.bed -b b.bed -sorted 2>&1 > /dev/null | grep "Error: Sorted input specified, " | cut -f1 -d ',' > obs check obs exp rm obs exp ########################################################### # Test enforcement of sort order when using -sorted option. # Show that detect chrom "jumping", i.e. chr1, chr2, then # back to chr1 ############################################################ echo -e " intersect.new.t49...\c" echo "Error: Sorted input specified" > exp $BT intersect -a recordsOutOfOrder.bed -b b.bed -sorted 2>&1 > /dev/null | grep "Error: Sorted input specified, " | cut -f1 -d ',' > obs check obs exp rm obs exp ########################################################### # Test that we throw an error for non-existant files ############################################################ echo -e " intersect.new.t50...\c" echo "Error: Unable to open file nonExistantFile.bed. Exiting." > exp $BT intersect -a nonExistantFile.bed -b b.bed -sorted 2>&1 > /dev/null | cat - >obs check obs exp rm obs exp ########################################################### # Test that we allow empty query files ############################################################ echo -e " intersect.new.t51...\c" touch exp touch dummy.txt $BT intersect -a dummy.txt -b b.bed 2>&1 > /dev/null | cat - > obs check obs exp rm obs exp dummy.txt ########################################################### # Test that we throw an error for unrecognized arguments ############################################################ echo -e " intersect.new.t52...\c" echo "***** ERROR: Unrecognized parameter: -wrongArg *****" > exp $BT intersect -a a.bed -b b.bed -wrongArg 2>&1 > /dev/null | tail -1 > obs check obs exp rm obs exp ########################################################### # Test that we can process a Bam file with no text in # it's header. ############################################################ echo -e " intersect.new.t53...\c" $BT intersect -a gdc.bam -b gdc.bam -bed > obs check obs gdc_exp rm obs ########################################################### # Test that if the query is BAM, and bed output is not # explicit, and they asked for an output option that is not # valid with BAM output, an error is thrown. ############################################################ echo -e " intersect.new.t54...\c" echo "***** ERROR: writeAllOverlap option is not valid with BAM query input, unless bed output is specified with -bed option. *****" > exp $BT intersect -a a.bam -b b.bed -wao 2>&1 > /dev/null | tail -1 > obs check obs exp rm obs exp ########################################################### # Test that gff files work correctly ############################################################ echo -e " intersect.new.t55...\c" echo \ "chr2L . UTR 51 70 0 + . ID=mRNA:xs2:UTR:41-70;Parent=mRNA:xs2; chr2L . CDS 71 100 0 + . ID=mRNA:xs2:CDS:71-130;Parent=mRNA:xs2; chr2L . exon 51 100 0 + . ID=mRNA:xs2:exon:41-130;Parent=mRNA:xs2; chr2L . mRNA 51 100 0 + . ID=mRNA:xs2;Parent=g2; chr2L . gene 51 100 0 + . ID=g2;" > exp $BT intersect -a gdc.gff -b gdc_one.bed > obs check obs exp rm obs exp ########################################################### # Test that we allow empty database files, unsorted ############################################################ echo -e " intersect.new.t56...\c" touch exp touch dummy.txt $BT intersect -a a.bed -b dummy.txt 2>&1 > /dev/null | cat - > obs check obs exp rm obs exp dummy.txt ########################################################### # Test that we allow empty database files, sorted ############################################################ echo -e " intersect.new.t57...\c" touch exp touch dummy.txt $BT intersect -a a.bed -b dummy.txt -sorted 2>&1 > /dev/null | cat - > obs check obs exp rm obs exp dummy.txt ########################################################### # Test that we allow empty database files, unsorted, with # -v (noHit) option ############################################################ echo -e " intersect.new.t58...\c" touch dummy.txt $BT intersect -a a.bed -b dummy.txt -v > obs check obs a.bed rm obs dummy.txt ########################################################### # Test that an empty query with header run with -header # option will print header ############################################################ echo -e " intersect.new.t59...\c" echo "#Random Header" >dummy.txt $BT intersect -a dummy.txt -b a.bed -header > obs check obs dummy.txt rm obs dummy.txt ########################################################### # Test that an empty query with header, gzipped, that # runs with -header option will print header ############################################################ echo -e " intersect.new.t60...\c" echo "#Random Header" >dummy.txt gzip dummy.txt echo "#Random Header" >exp $BT intersect -a dummy.txt.gz -b a.bed -header > obs check obs exp rm obs dummy.txt.gz exp ########################################################### # Test that an empty query with header, bgzipped, that # runs with -header option will print header ############################################################ echo -e " intersect.new.t61...\c" echo "#Random Header" | $htsutil bgzfcompress - dummy.txt.gz echo "#Random Header" >exp $BT intersect -a dummy.txt.gz -b a.bed -header > obs check obs exp rm obs dummy.txt.gz exp ########################################################### # Test that an empty VCF query with header that # runs with -header option will print header ############################################################ echo -e " intersect.new.t62...\c" $BT intersect -a headerOnly.vcf -b a.bed -header > obs check obs headerOnly.vcf rm obs ########################################################### # Test that files with DOS newline characters, '\r', # and/or extra tabs at end of line are handled ############################################################ echo -e " intersect.new.t63...\c" echo \ "Error: Type checker found wrong number of fields while tokenizing data line. Perhaps you have extra TAB at the end of your line? Check with \"cat -t\"" >exp $BT intersect -a dosLineChar_a.bed -b dosLineCharWithExtraTab_b.bed -v 2>&1 > /dev/null | cat - > obs check exp obs rm exp obs ########################################################### # Test that files with no newlines at all are handled ############################################################ echo -e " intersect.new.t64...\c" echo "chr17 7577068 7577157" > exp $BT intersect -a oneRecordNoNewline.bed -b oneRecordNoNewline.bed > obs check obs exp rm obs exp ########################################################### # Test zero length intersections in non-bam files. ############################################################ echo -e " intersect.new.t65...\c" echo \ "chr1 5 15 r1 chr1 9 9 m3 0 chr1 7 12 r3 chr1 9 9 m3 0" > exp $BT intersect -a a_testZeroLen.bed -b b_testZeroLen.bed -wo > obs check exp obs rm exp obs ########################################################### # Test zero length intersections in non-bam files, -sorted ############################################################ echo -e " intersect.new.t66...\c" echo \ "chr1 5 15 r1 chr1 9 9 m3 0 chr1 7 12 r3 chr1 9 9 m3 0" > exp $BT intersect -a a_testZeroLen.bed -b b_testZeroLen.bed -wo -sorted> obs check exp obs rm exp obs ########################################################### # Test vcf struct var intersection ############################################################ echo -e " intersect.new.t67a...\c" echo \ "19 252806 791255 G 70.90 . TOOL=LUMPY;SVTYPE=DEL;SVLEN=-389,-4611;END=253195;STR=+-:4;IMPRECISE;CIPOS=-2,137;CIEND=0,0;EVENT=791255;SUP=4;PESUP=4;SRSUP=0;EV=PE;PRIN;CSQ=intergenic_variant|||||||||| 19 256900 791255 G T 70.90 . TOOL=LUMPY;SVTYPE=DEL;SVLEN=-389,-4611;END=253195;STR=+-:4;IMPRECISE;CIPOS=-2,137;CIEND=0,0;EVENT=791255;SUP=4;PESUP=4;SRSUP=0;EV=PE;PRIN;CSQ=intergenic_variant|||||||||| 19 260365 791256 C 33.71 . TOOL=LUMPY;SVTYPE=DEL;SVLEN=-680;END=261045;STR=+-:4;IMPRECISE;CIPOS=-1,257;CIEND=0,0;EVENT=791256;SUP=4;PESUP=4;SRSUP=0;EV=PE;PRIN;CSQ=upstream_gene_variant|||ENSG00000271846|CTD-3113P16.9|ENST00000607399|||||processed_pseudogene 19 260800 791256 C 33.71 . TOOL=LUMPY;SVTYPE=DEL;SVLEN=680;END=261045;STR=+-:4;IMPRECISE;CIPOS=-1,257;CIEND=0,0;EVENT=791256;SUP=4;PESUP=4;SRSUP=0;EV=PE;PRIN;CSQ=upstream_gene_variant|||ENSG00000271846|CTD-3113P16.9|ENST00000607399|||||processed_pseudogene 19 265134 791257 A 20.25 . TOOL=LUMPY;SVTYPE=DEL;SVLEN=-558;END=265692;STR=+-:4;IMPRECISE;CIPOS=-1,196;CIEND=0,0;EVENT=791257;SUP=4;PESUP=4;SRSUP=0;EV=PE;PRIN;CSQ=intergenic_variant|||||||||| 19 265500 791257 A 20.25 . TOOL=LUMPY;SVTYPE=DEL;SVLEN=-558;END=265692;STR=+-:4;IMPRECISE;CIPOS=-1,196;CIEND=0,0;EVENT=791257;SUP=4;PESUP=4;SRSUP=0;EV=PE;PRIN;CSQ=intergenic_variant|||||||||| 19 265986 791258 A 22.15 . TOOL=LUMPY;SVTYPE=DEL;SVLEN=-401;END=266387;STR=+-:6;IMPRECISE;CIPOS=-2,87;CIEND=0,0;EVENT=791258;SUP=6;PESUP=6;SRSUP=0;EV=PE;PRIN;CSQ=intergenic_variant|||||||||| 19 265500 791257 A 20.25 . TOOL=LUMPY;SVTYPE=DEL;SVLEN=-558;END=265692;STR=+-:4;IMPRECISE;CIPOS=-1,196;CIEND=0,0;EVENT=791257;SUP=4;PESUP=4;SRSUP=0;EV=PE;PRIN;CSQ=intergenic_variant|||||||||| 19 265986 791258 A 22.15 . TOOL=LUMPY;SVTYPE=DEL;SVLEN=-401;END=266387;STR=+-:6;IMPRECISE;CIPOS=-2,87;CIEND=0,0;EVENT=791258;SUP=6;PESUP=6;SRSUP=0;EV=PE;PRIN;CSQ=intergenic_variant|||||||||| 19 266003 791258 A C 22.15 . TOOL=LUMPY;SVTYPE=DEL;SVLEN=-401;END=266387;STR=+-:6;IMPRECISE;CIPOS=-2,87;CIEND=0,0;EVENT=791258;SUP=6;PESUP=6;SRSUP=0;EV=PE;PRIN;CSQ=intergenic_variant||||||||||" > exp $BT intersect -a a_vcfSVtest.vcf -b b_vcfSVtest.vcf -wa -wb >obs check exp obs rm exp obs echo -e " intersect.new.t67b...\c" echo -n "" > exp $BT intersect -a a_vcfSVtest.vcf -b b_vcfSVtest.vcf -wa -wb -v >obs check exp obs rm exp obs ########################################################### # Test vcf struct var intersection, sorted ############################################################ echo -e " intersect.new.t68a...\c" echo \ "19 252806 791255 G 70.90 . TOOL=LUMPY;SVTYPE=DEL;SVLEN=-389,-4611;END=253195;STR=+-:4;IMPRECISE;CIPOS=-2,137;CIEND=0,0;EVENT=791255;SUP=4;PESUP=4;SRSUP=0;EV=PE;PRIN;CSQ=intergenic_variant|||||||||| 19 256900 791255 G T 70.90 . TOOL=LUMPY;SVTYPE=DEL;SVLEN=-389,-4611;END=253195;STR=+-:4;IMPRECISE;CIPOS=-2,137;CIEND=0,0;EVENT=791255;SUP=4;PESUP=4;SRSUP=0;EV=PE;PRIN;CSQ=intergenic_variant|||||||||| 19 260365 791256 C 33.71 . TOOL=LUMPY;SVTYPE=DEL;SVLEN=-680;END=261045;STR=+-:4;IMPRECISE;CIPOS=-1,257;CIEND=0,0;EVENT=791256;SUP=4;PESUP=4;SRSUP=0;EV=PE;PRIN;CSQ=upstream_gene_variant|||ENSG00000271846|CTD-3113P16.9|ENST00000607399|||||processed_pseudogene 19 260800 791256 C 33.71 . TOOL=LUMPY;SVTYPE=DEL;SVLEN=680;END=261045;STR=+-:4;IMPRECISE;CIPOS=-1,257;CIEND=0,0;EVENT=791256;SUP=4;PESUP=4;SRSUP=0;EV=PE;PRIN;CSQ=upstream_gene_variant|||ENSG00000271846|CTD-3113P16.9|ENST00000607399|||||processed_pseudogene 19 265134 791257 A 20.25 . TOOL=LUMPY;SVTYPE=DEL;SVLEN=-558;END=265692;STR=+-:4;IMPRECISE;CIPOS=-1,196;CIEND=0,0;EVENT=791257;SUP=4;PESUP=4;SRSUP=0;EV=PE;PRIN;CSQ=intergenic_variant|||||||||| 19 265500 791257 A 20.25 . TOOL=LUMPY;SVTYPE=DEL;SVLEN=-558;END=265692;STR=+-:4;IMPRECISE;CIPOS=-1,196;CIEND=0,0;EVENT=791257;SUP=4;PESUP=4;SRSUP=0;EV=PE;PRIN;CSQ=intergenic_variant|||||||||| 19 265986 791258 A 22.15 . TOOL=LUMPY;SVTYPE=DEL;SVLEN=-401;END=266387;STR=+-:6;IMPRECISE;CIPOS=-2,87;CIEND=0,0;EVENT=791258;SUP=6;PESUP=6;SRSUP=0;EV=PE;PRIN;CSQ=intergenic_variant|||||||||| 19 265500 791257 A 20.25 . TOOL=LUMPY;SVTYPE=DEL;SVLEN=-558;END=265692;STR=+-:4;IMPRECISE;CIPOS=-1,196;CIEND=0,0;EVENT=791257;SUP=4;PESUP=4;SRSUP=0;EV=PE;PRIN;CSQ=intergenic_variant|||||||||| 19 265986 791258 A 22.15 . TOOL=LUMPY;SVTYPE=DEL;SVLEN=-401;END=266387;STR=+-:6;IMPRECISE;CIPOS=-2,87;CIEND=0,0;EVENT=791258;SUP=6;PESUP=6;SRSUP=0;EV=PE;PRIN;CSQ=intergenic_variant|||||||||| 19 266003 791258 A C 22.15 . TOOL=LUMPY;SVTYPE=DEL;SVLEN=-401;END=266387;STR=+-:6;IMPRECISE;CIPOS=-2,87;CIEND=0,0;EVENT=791258;SUP=6;PESUP=6;SRSUP=0;EV=PE;PRIN;CSQ=intergenic_variant||||||||||" > exp $BT intersect -a a_vcfSVtest.vcf -b b_vcfSVtest.vcf -wa -wb -sorted >obs check exp obs rm exp obs echo -e " intersect.new.t68b...\c" echo -n "" > exp $BT intersect -a a_vcfSVtest.vcf -b b_vcfSVtest.vcf -wa -wb -v -sorted>obs check exp obs rm exp obs ########################################################### # Test intersect -loj with multiple databases ############################################################ echo -e " intersect.new.t69...\c" echo \ "1 100 200 a1 ax 1 1 100 200 b1 bx 1 300 400 a2 ay . . -1 -1 . . 1 400 500 a3 az . . -1 -1 . . 2 500 600 a4 aq . . -1 -1 . ." > exp $BT intersect -a null_a.bed -b null_b.bed null_c.bed -loj > obs check exp obs rm exp obs ########################################################### # Test intersect -loj with multiple databases and -names ############################################################ echo -e " intersect.new.t70...\c" echo \ "1 100 200 a1 ax b 1 100 200 b1 bx 1 300 400 a2 ay . . -1 -1 . . 1 400 500 a3 az . . -1 -1 . . 2 500 600 a4 aq . . -1 -1 . ." > exp $BT intersect -a null_a.bed -b null_b.bed null_c.bed -loj -names b c > obs check exp obs rm exp obs ########################################################### # Test intersect -wao with multiple databases ############################################################ echo -e " intersect.new.t71...\c" echo \ "1 100 200 a1 ax 1 1 100 200 b1 bx 100 1 300 400 a2 ay . . -1 -1 . . 0 1 400 500 a3 az . . -1 -1 . . 0 2 500 600 a4 aq . . -1 -1 . . 0" > exp $BT intersect -a null_a.bed -b null_b.bed null_c.bed -wao > obs check exp obs rm exp obs ########################################################### # Test intersect -wao with multiple databases and -names ############################################################ echo -e " intersect.new.t72...\c" echo \ "1 100 200 a1 ax b 1 100 200 b1 bx 100 1 300 400 a2 ay . . -1 -1 . . 0 1 400 500 a3 az . . -1 -1 . . 0 2 500 600 a4 aq . . -1 -1 . . 0" > exp $BT intersect -a null_a.bed -b null_b.bed null_c.bed -wao -names b c > obs check exp obs rm exp obs [[ $FAILURES -eq 0 ]] || exit 1; ########################################################### # Test intersect with cram without a reference provided ############################################################ echo -e " intersect.new.t73...\c" echo \ "FCC1MK2ACXX:2:2110:4301:28831# 99 chr1 10004 0 100M = 10047 140 * * PG:Z:novoalign AM:i:2 SM:i:2 MQ:i:0 PQ:i:219 UQ:i:0 AS:i:0 RG:Z:NCH411GBM_CD133low FCC1MK2ACXX:2:2110:4301:28831# 147 chr1 10047 0 3S97M = 10004 -140 * * PG:Z:novoalign AM:i:2 SM:i:70 MQ:i:0 PQ:i:219 UQ:i:194 AS:i:194 RG:Z:NCH411GBM_CD133low" > exp $BT intersect -a a.cram -b b.cram | $htsutil viewbamrecords > obs check exp obs rm exp obs [[ $FAILURES -eq 0 ]] || exit 1; ########################################################### # Test intersect with with pos > than 512Mb ############################################################ echo -e " intersect.new.t74...\c" echo \ "1 1000000004 1000000005 1 10000000004 10000000005 1 30000000000 30000000005" > exp $BT intersect -a large_a.bed -b large_b.bed > obs check exp obs rm exp obs [[ $FAILURES -eq 0 ]] || exit 1; ########################################################### # Test intersect with cram with a reference provided ############################################################ echo -e " intersect.new.t75...\c" echo \ "FCC1MK2ACXX:2:2110:4301:28831# 99 chr1 10004 0 100M = 10047 140 CCCTAACCCTAACCCTAACCCTAACCCTAACCCTAACCCTAACCCTAACCCTAACCCTAACCCTAACCCTAACCCTAACCCTAACCCTAACCCTAACCCT CCCFFFFFHHHHHJJIJJJJIGIIIJIGIGJJJJIJJJJIJIIJJDIIIJJIJEHEE@GAHHGE@CEFB;A>AB=??5?B?2?exp CRAM_REFERENCE=test_ref.fa $BT intersect -a a.cram -b b.cram | $htsutil viewcramrecords - test_ref.fa > obs check exp obs rm exp obs [[ $FAILURES -eq 0 ]] || exit 1; ########################################################### # Test intersect with bam has no text header ############################################################ echo -e " intersect.new.t76...\c" echo \ "GA5:3:2:1710:1301#0 0 dummy_chr 1279 18 76M * 0 0 GAACTCCTGACCTCAGGTGATCTGCCCGCCTTGGCCTCCCAAAGTGCTGGAATTACAGGCATGAGCCACCGTGCCC 6->;B==?B?AAA??9B19;?A=9:?999;=4=6A9/8;4==;1';;3= XT:A:U NM:i:0 X0:i:1 X1:i:3 XM:i:0 XO:i:0 XG:i:0 MD:Z:76 XA:Z:chr14,+56265423,76M,1;chr14,+91530561,76M,1;chr2,+230545178,76M,1; GA5:3:24:462:583#0 0 dummy_chr 128882 37 76M * 0 0 TAAAAAAAGGACAGTGACGCACCTTGTATAGCGATGTGTCATCTAAAACATCTATTCAAAGAACAGAAGACTCACC BBABBBB@BBBBBA?BBBBBBAA@AB?BBBA@B=>@?@;@?@?A>=1=?>??>?;;;?>8999;;9;;< XT:A:U NM:i:3 X0:i:1 X1:i:0 XM:i:3 XO:i:0 XG:i:0 MD:Z:6C21G30G16 GA5:3:29:1241:1653#0 0 dummy_chr 5591013 37 76M * 0 0 TCATGCACACACAGACAGCTGTCGGGGGATGCATGCCAACCAGAGGGGCCACACATATACCGTGTTGATGGGACAG BBBBBBACBCBBBBBBBBBBBABBABBB@AA>@?@?@>=????B@B?AABB?@>?BA?>AB;??A?6;=AAAAA=>3=9;@;===6,=?;;5==;6 XT:A:U NM:i:0 X0:i:1 X1:i:0 XM:i:0 XO:i:0 XG:i:0 MD:Z:76 GA5:3:31:677:1537#0 16 dummy_chr 11880931 37 76M * 0 0 GAGGGTTTGAGAGAGCAGCCAGGAGAGCTTAGGGTCTCAGGGTGTCCCAGACCCCGACACCGGCCAGTGGCGGAAG ###################>9==9=9?>????>>?>8>>??AA?>A??>A4AA?AA?B=ABBBBBBBBBBBBBBBB XT:A:U NM:i:0 X0:i:1 X1:i:0 XM:i:0 XO:i:0 XG:i:0 MD:Z:76 GA5:3:49:1480:1116#0 16 dummy_chr 11913868 37 76M * 0 0 GGGAGGAGGCCAGGACTTCAGGGACCCACAGCCATCACCTCCCTCCCCTGCCCCCTACACACCAACTCTCTGGAAA #################################44:4=944==;=???>=?>==??=A=A;ABA?A?AABAAABBB XT:A:U NM:i:1 X0:i:1 X1:i:0 XM:i:1 XO:i:0 XG:i:0 MD:Z:0T75 GA5:3:61:213:1812#0 16 dummy_chr 13030396 37 76M * 0 0 GGTCCGGCGGGGTCGGACTGGACCAGCTGTTGGGCTTTGTTTGCTCTTTTTACGAATTGAAAAACTGAAGCCAGGA /=81,5948=485=4,),1;;7:87:6=;;@@AB=C8A@@BAB=>5>BBBB>BBAAA9ABA@B4B;BBBBBBBBCB XT:A:U NM:i:1 X0:i:1 X1:i:0 XM:i:1 XO:i:0 XG:i:0 MD:Z:0T75 GA5:3:116:1581:552#0 16 dummy_chr 15055984 37 76M * 0 0 AGAAAGCCTAAGGTCAGGGTGCCAGCAGGTTTGGTGTCTGGTGAGGTACCCATCTCTGCTTCTAAGGCAGAGCCTT 48887429,3=;98<8<8@;<=?8@??98@@@<=AA>@@?B?A@@BA6BA@=@BABBB???B@BBBBBABBCBB?B XT:A:U NM:i:0 X0:i:1 X1:i:0 XM:i:0 XO:i:0 XG:i:0 MD:Z:76" > exp $BT intersect -a notexthdr.bam -b notexthdr.bam | $htsutil viewbamrecords > obs check exp obs rm exp obs [[ $FAILURES -eq 0 ]] || exit 1; ########################################################### # Test intersect with 2G io buffer, shouldn't overflow ############################################################ echo -e " intersect.new.t77...\c" echo -n "" > exp $BT intersect -iobuf 2G -ubam -S -u -sorted -b a.bam -a a.bed >obs check exp obs rm exp obs [[ $FAILURES -eq 0 ]] || exit 1; ########################################################### # Test intersect preserve the text header in bam ############################################################ echo -e " intersect.new.t78...\c" echo -e "@HD VN:1.5 SO:coordinate" > exp echo "@HD VN:1.5 SO:coordinate" | $htsutil samtobam - - | $BT intersect -a /dev/stdin -b b.bed | $htsutil viewbam >obs check exp obs rm exp obs [[ $FAILURES -eq 0 ]] || exit 1; ########################################################### # Test intersect recognize "*" as a valid strand char ############################################################ echo -e " intersect.new.t79...\c" echo -e "GL000008.2 118286 119434 Pituitary_00000002 999 * GL000008.2 158006 158759 Pituitary_00000012 999 + GL000009.2 78532 79175 Pituitary_00000033 999 *" > exp $BT intersect -s -v -a strand_with_star.a.bed -b strand_with_star.b.bed > obs check exp obs rm exp obs [[ $FAILURES -eq 0 ]] || exit 1; ########################################################### # Test utral bed4 intersection ############################################################ echo -e " intersect.new.t80...\c" cp ultra-long-bed4.bed exp $BT intersect -a ultra-long-bed4.bed -b ultra-long-bed4.bed > obs check exp obs rm exp obs [[ $FAILURES -eq 0 ]] || exit 1; ########################################################### # Test -C that got -b parameter first ############################################################ echo -e " intersect.new.t81...\c" echo -e "chr1 10 20 a1 1 + 0 chr1 100 200 a2 2 - 2" > exp $BT intersect -b b.bed -a a.bed -C > obs check exp obs rm exp obs 1 1000000004 1000000007 1 10000000004 10000000007 1 30000000000 30000000008 BCX[hU1JbADD)sMURC[,kMBMPbjo$"Uij> ^з"XhHY?̜m9kcw<2vJݳS3{Fj=Omlн [Hmk}dv`uQE:{oM+cS]cvL'G*Olf2Iik4\J.iΜ%ʘWG'!Z}2JHjL9uFͅ"s2b$ܲ [¥2sR6Zhf+:gTV#Pf'x'"|fPYZH/ C ɐM!Z3YtBLelRfuL:)cQ-G`oBP0zMG~8zZ pRdiV0f39S0Lڿ,| I9R@Ν>D$YKں6 wTg@ CVdIX*J_C8SRM=.?:8]߂P1Y:\)\ 64*Xҫ3jpx5 ߜ0LRV&9 hffO F02saFFeN=s3P gmG1_^/*Y[ȣ(# $f%((_)4BX tLHPjyLs"o"זZ""ܭ! 0u"^D7P#+먟X*QP.AF !e,AABXW0 ApeQ'H#]A1zSvpu"<CMDx NܸfńyR 4s"#3~[,3Md5t\x"Ua_7G﹫KD֎^ZM N _Kv%J$ =M$-dZlˏWD pk .Go@ΓKmXѲpd}€[{}%9;-7ԎZ^e?=_J+Շ&0s?./7'pK˚څڲۚB׆bKW WJ~ּq)(x;7_7pewp&-'ܘ2=%̝KMFx" A5<_ |Ѵ̵ePz``B5v~=Np%#ELH($胳=o%ըKy5?~BC^%}5#j/"j .~:"j KrJsZWZeSΫwi-6?7}I8O j 5o#j!j3>DVcs(C%.!s >B ȝ}"j "jo"jvD6_[i ͿN+|G[Sk?HU:tEޔA VyBCchr7 33059403 33059403 chr1 40 100 chr1 10 20 345.7 why? - chr1 15 25 a1 100 + chr1 30 40 a1 100 + chr2 15 25 a2 100 + chr2 30 40 a1 100 + chr10 15 25 a3 100 + chr10 30 40 a1 100 + chr11 15 25 a4 100 + chr11 30 40 a1 100 + chrX 15 25 a5 100 + chrX 30 40 a1 100 + chrM 15 25 a6 100 + chrM 30 40 a1 100 + 1 pseudogene exon 32 32 . - . gene_id "ENSG00000224777"; transcript_id "ENST00000424047"; exon_number "1"; gene_name "OR4F2P"; transcript_name "OR4F2P-001"; BCY]lW>I"V/(ܿ+ٵkj64!2ޝqv֎SR%T*"*MjJEy#x" ̝;3LwpΙ{{oN܃YTYJkmns\3lg{*gVg1&Fvvֶ]Dk @8'm`64Tb[E@aS'-$B" ئS;RTG%aDĞh! cZT'Iba lIllt=He %} PΨ 䏁Al  ¨th"qZ#YaYj'"`,T$< ,G6\8bCĠԡ#Wɰe0s༬86&~0 qеG}&%Z R^pƋ!: vgmgUl.6l^ zbn 51\;aG-Έ־f'2>2^y*kᠳBa/oB' 8DsL*#l'Nmx!S'V։,+'v 7 -Ju`8RZK2^G1^'BK袆hub!!^9TGz^6"zm=revdOCyɒ_4Q•#ǦVgHah( ['=%fw[Hzl6//&D )^^erŒ)>~wsx+#Z.  N=cHHJ-7r)c[N7,ή_w]Qxcwt Ʀ3,ZKjZj?ݚWꙵs#7%0pfT;^,a5}íg_lU]o<&^F 9)uFx0PuEAbú 4l+nqA-FphYS\( {ڨ [nsum;rn;ֶ]>lݶW__biu"Y&KAecQ`+^l_O'nI > ׻J`p_>=I`AoዕX`'bÝ_85G?HhU :$ 9…ɊfpdΨpI8M2y|e)ժy*uz%ժ))\<}ӏD^˸PsJf;">ER a$ܨ&9ĘDΨ3wI\Cޘl*}#wƳ(*1&ܘ } dckLIdޚSSϹ)pOj͍;ykR$n~x _̫1jO>V{ &_6 _/P5w^ͫ2}XFp]p KL/)y-{*6l؂O6|jl^y@5_=W&5V ^~@m¯Pto-Ps~9Y"xj S5/)Z' &L?]`jv|s6E"BC^K0_vJJei6d:S7ыc9eBj1t瑼oup$RW` 𩕜sҋn󐅬˺!Yx:{pV(bEa.$ 0<fGk7( &q]5)jY;HA˳ 5쾄zz;\q:en(hz3L^MƲn9D3,+|wpyE'/InH͊IilMe5iuR2]4cѰakeն?#Qh&BCBCYYhE>iko_43k.VV-k&$f AEqhݵ> ME}A\з"(_*bw2 gfwΙof;< 4%}T`NOkL Q'pNy>窘l|:_$kr^[UYUXHV1d4Sf1DST5TjRT81ϻb(ǟ?0^J 1=긹Sl(YWR~b2U.o(*5ZYyy68x\*3o%[ |xWqX0|}цc75Nj.}~H Ed WGbJa rJKWcaOc#%h>>L"$Oʣ#xPA]>o`2? 8ge4+FXz5P -| ;@q{}\|_$7_%`ęhX_B`apL{`/{ޭ;䎳Vu?k85?1iߺc<+N_̂ODDNQ%BCchr1 0 50 three_blocks_match 0 + 0 0 0 3 10,10,10, 0,20,40, ##fileformat=VCFv4.1 #CHROM POS ID REF ALT QUAL FILTER INFO chr1 1 a G 70.90 . TOOL=LUMPY;SVTYPE=DEL;SVLEN=-389,-4611;END=253195;STR=+-:4;IMPRECISE;CIPOS=-2,137;CIEND=0,0;EVENT=791255;SUP=4;PESUP=4;SRSUP=0;EV=PE;PRIN;CSQ=intergenic_variant|||||||||| chr1 4 a G 70.90 . TOOL=LUMPY;SVTYPE=DEL;END=253195;STR=+-:4;IMPRECISE;CIPOS=-2,137;CIEND=0,0;EVENT=791255;SUP=4;PESUP=4;SRSUP=0;EV=PE;PRIN;CSQ=intergenic_variant||||||||||;SVLEN=-45,800,2 chr2 1000 16385 A 0 - 0 0 0 2 1,1, 0,15384, chr2 6000 6001 B 0 - 0 0 0 1 1, 0, BCisreb``pp 23tK J/JK,Ir J(222425032bfb m>˟lSBCg@ O!F9 ?RrAԊxc "NJN**JJJJʊr2j@JS]C 4|]L fV@bQX,)χXYb,fXpfc`p ^iD9w^BCX 10 30 A2 1 + 0 30 255,0,0 1 20 0 chr1 10 20 345.7 why? - chr1 11 21 345.7 why? + ##fileformat=VCFv4.1 chr1 1 a G 70.90 . TOOL=LUMPY;SVTYPE=DEL;SVLEN=-389,-4611;END=253195;STR=+-:4;IMPRECISE;CIPOS=-2,137;CIEND=0,0;EVENT=791255;SUP=4;PESUP=4;SRSUP=0;EV=PE;PRIN;CSQ=intergenic_variant|||||||||| chr1 4 a G 70.90 . TOOL=LUMPY;SVTYPE=DEL;END=253195;STR=+-:4;IMPRECISE;CIPOS=-2,137;CIEND=0,0;EVENT=791255;SUP=4;PESUP=4;SRSUP=0;EV=PE;PRIN;CSQ=intergenic_variant||||||||||;SVLEN=-45,800,2chr1 10 20 a1 1 + chr1 100 200 a2 2 - CRAMb.cramML7uOo8{؋)MQ4k׮O4=lHS)NBҎ~Y9޼<`?>||G"h,,Ye9-l\X:lZ)}ƅ"F֓,nc~VZ0-8BKUM\?A V%7aǷ-> zĪ}l\,F_I2s,3+T 포l ><ƿ6 ߂ ғװ$?'3}c3+ѬV]t(RTn';4 Y0l@w Kk) ]Z%#'Fjʜ ֐hޏ1봅I)T_6/qGϯ.I:89v$Bq?8!7vhC,9ph =,8:ī[CT;LYZ:3<;P܂Ox^Ci0ܜNgab 8|ԩ!>ohDcWJ[ݼë2TߣjQ4KE !D4l[7/ds9n2CIX/k5@d|!6؄qmojF)MWDHt7MMNs;bi{{ITD8PGZAMCSMCMQCPQCUQCASCPGZIHCNHCHICAMCSMCMQCPQCUQCASCZSZSMRNAPuBFCFRLdAPRGMFNSNPTSTL FNIN BB*%MQRN QS RISC ASC ASCPQC PQCSMC SMCAMC AMCHIC HICIHC IHCMQC MQCPGZ PGZZSZ ZSZUQC UQCNHC NHCTT  ASCPQCSMCAMCHICIHCMQCPGZZSZUQCNHC{s1,Kx+rF 6/ N>ssv66rt222442160206Tfpsv62 ut2HZ[*3.Ŵ><  @7h1gKa7$J57M#PҌ&;*﮼;\3Z7lفTjvA+0RL{oNm6Kn Ui<c80c#T c`EC&cd#X&kF׈[n`̀? c`i"6I*ASCc`AAPQC r]fGSMCcrؔPєGAMCcrؔPaHICcfԲIHCcePBMQCc`ECPGZ!/OLcC0߇qwZSZ bhmUQCc`Aʍ?NHCc <gEOFOcK##fileformat=VCFv4.1 19 252806 791255 G 70.90 . TOOL=LUMPY;SVTYPE=DEL;SVLEN=-389,-4611;END=253195;STR=+-:4;IMPRECISE;CIPOS=-2,137;CIEND=0,0;EVENT=791255;SUP=4;PESUP=4;SRSUP=0;EV=PE;PRIN;CSQ=intergenic_variant|||||||||| 19 260365 791256 C 33.71 . TOOL=LUMPY;SVTYPE=DEL;SVLEN=-680;END=261045;STR=+-:4;IMPRECISE;CIPOS=-1,257;CIEND=0,0;EVENT=791256;SUP=4;PESUP=4;SRSUP=0;EV=PE;PRIN;CSQ=upstream_gene_variant|||ENSG00000271846|CTD-3113P16.9|ENST00000607399|||||processed_pseudogene 19 265134 791257 A 20.25 . TOOL=LUMPY;SVTYPE=DEL;SVLEN=-558;END=265692;STR=+-:4;IMPRECISE;CIPOS=-1,196;CIEND=0,0;EVENT=791257;SUP=4;PESUP=4;SRSUP=0;EV=PE;PRIN;CSQ=intergenic_variant|||||||||| 19 265986 791258 A 22.15 . TOOL=LUMPY;SVTYPE=DEL;SVLEN=-401;END=266387;STR=+-:6;IMPRECISE;CIPOS=-2,87;CIEND=0,0;EVENT=791258;SUP=6;PESUP=6;SRSUP=0;EV=PE;PRIN;CSQ=intergenic_variant|||||||||| # This is line 0 of a file with a large header. # This is line 1 of a file with a large header. # This is line 2 of a file with a large header. # This is line 3 of a file with a large header. # This is line 4 of a file with a large header. # This is line 5 of a file with a large header. # This is line 6 of a file with a large header. # This is line 7 of a file with a large header. # This is line 8 of a file with a large header. # This is line 9 of a file with a large header. # This is line 10 of a file with a large header. # This is line 11 of a file with a large header. # This is line 12 of a file with a large header. # This is line 13 of a file with a large header. # This is line 14 of a file with a large header. # This is line 15 of a file with a large header. # This is line 16 of a file with a large header. # This is line 17 of a file with a large header. # This is line 18 of a file with a large header. # This is line 19 of a file with a large header. # This is line 20 of a file with a large header. # This is line 21 of a file with a large header. # This is line 22 of a file with a large header. # This is line 23 of a file with a large header. # This is line 24 of a file with a large header. # This is line 25 of a file with a large header. # This is line 26 of a file with a large header. # This is line 27 of a file with a large header. # This is line 28 of a file with a large header. # This is line 29 of a file with a large header. # This is line 30 of a file with a large header. # This is line 31 of a file with a large header. # This is line 32 of a file with a large header. # This is line 33 of a file with a large header. # This is line 34 of a file with a large header. # This is line 35 of a file with a large header. # This is line 36 of a file with a large header. # This is line 37 of a file with a large header. # This is line 38 of a file with a large header. # 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This is line 562 of a file with a large header. # This is line 563 of a file with a large header. # This is line 564 of a file with a large header. # This is line 565 of a file with a large header. # This is line 566 of a file with a large header. # This is line 567 of a file with a large header. # This is line 568 of a file with a large header. # This is line 569 of a file with a large header. # This is line 570 of a file with a large header. # This is line 571 of a file with a large header. # This is line 572 of a file with a large header. # This is line 573 of a file with a large header. # This is line 574 of a file with a large header. # This is line 575 of a file with a large header. # This is line 576 of a file with a large header. # This is line 577 of a file with a large header. # This is line 578 of a file with a large header. # This is line 579 of a file with a large header. # This is line 580 of a file with a large header. # This is line 581 of a file with a large header. # This is line 582 of a file with a large header. # This is line 583 of a file with a large header. # This is line 584 of a file with a large header. # This is line 585 of a file with a large header. # This is line 586 of a file with a large header. # This is line 587 of a file with a large header. # This is line 588 of a file with a large header. # This is line 589 of a file with a large header. # This is line 590 of a file with a large header. # This is line 591 of a file with a large header. # This is line 592 of a file with a large header. # This is line 593 of a file with a large header. # This is line 594 of a file with a large header. # This is line 595 of a file with a large header. # This is line 596 of a file with a large header. # This is line 597 of a file with a large header. # This is line 598 of a file with a large header. # This is line 599 of a file with a large header. # This is line 600 of a file with a large header. # This is line 601 of a file with a large header. # This is line 602 of a file with a large header. # This is line 603 of a file with a large header. # This is line 604 of a file with a large header. # This is line 605 of a file with a large header. # This is line 606 of a file with a large header. # This is line 607 of a file with a large header. # This is line 608 of a file with a large header. # This is line 609 of a file with a large header. # This is line 610 of a file with a large header. # This is line 611 of a file with a large header. # This is line 612 of a file with a large header. # This is line 613 of a file with a large header. # This is line 614 of a file with a large header. # This is line 615 of a file with a large header. # This is line 616 of a file with a large header. # This is line 617 of a file with a large header. # This is line 618 of a file with a large header. # This is line 619 of a file with a large header. # This is line 620 of a file with a large header. # This is line 621 of a file with a large header. # This is line 622 of a file with a large header. # This is line 623 of a file with a large header. # This is line 624 of a file with a large header. # This is line 625 of a file with a large header. # This is line 626 of a file with a large header. # This is line 627 of a file with a large header. # This is line 628 of a file with a large header. # This is line 629 of a file with a large header. # This is line 630 of a file with a large header. # This is line 631 of a file with a large header. # This is line 632 of a file with a large header. # This is line 633 of a file with a large header. # This is line 634 of a file with a large header. # This is line 635 of a file with a large header. # This is line 636 of a file with a large header. # This is line 637 of a file with a large header. # This is line 638 of a file with a large header. # This is line 639 of a file with a large header. # This is line 640 of a file with a large header. # This is line 641 of a file with a large header. # This is line 642 of a file with a large header. # This is line 643 of a file with a large header. # This is line 644 of a file with a large header. # This is line 645 of a file with a large header. # This is line 646 of a file with a large header. # This is line 647 of a file with a large header. # This is line 648 of a file with a large header. # This is line 649 of a file with a large header. # This is line 650 of a file with a large header. # This is line 651 of a file with a large header. # This is line 652 of a file with a large header. # This is line 653 of a file with a large header. # This is line 654 of a file with a large header. # This is line 655 of a file with a large header. # This is line 656 of a file with a large header. # This is line 657 of a file with a large header. # This is line 658 of a file with a large header. # This is line 659 of a file with a large header. # This is line 660 of a file with a large header. # This is line 661 of a file with a large header. # This is line 662 of a file with a large header. # This is line 663 of a file with a large header. # This is line 664 of a file with a large header. # This is line 665 of a file with a large header. # This is line 666 of a file with a large header. # This is line 667 of a file with a large header. # This is line 668 of a file with a large header. # This is line 669 of a file with a large header. # This is line 670 of a file with a large header. # This is line 671 of a file with a large header. # This is line 672 of a file with a large header. # This is line 673 of a file with a large header. # This is line 674 of a file with a large header. # This is line 675 of a file with a large header. # This is line 676 of a file with a large header. # This is line 677 of a file with a large header. # This is line 678 of a file with a large header. # This is line 679 of a file with a large header. # This is line 680 of a file with a large header. # This is line 681 of a file with a large header. # This is line 682 of a file with a large header. # This is line 683 of a file with a large header. # This is line 684 of a file with a large header. # This is line 685 of a file with a large header. # This is line 686 of a file with a large header. # This is line 687 of a file with a large header. # This is line 688 of a file with a large header. # This is line 689 of a file with a large header. # This is line 690 of a file with a large header. # This is line 691 of a file with a large header. # This is line 692 of a file with a large header. # This is line 693 of a file with a large header. # This is line 694 of a file with a large header. # This is line 695 of a file with a large header. # This is line 696 of a file with a large header. # This is line 697 of a file with a large header. # This is line 698 of a file with a large header. # This is line 699 of a file with a large header. # This is line 700 of a file with a large header. # This is line 701 of a file with a large header. # This is line 702 of a file with a large header. # This is line 703 of a file with a large header. # This is line 704 of a file with a large header. # This is line 705 of a file with a large header. # This is line 706 of a file with a large header. # This is line 707 of a file with a large header. # This is line 708 of a file with a large header. # This is line 709 of a file with a large header. # This is line 710 of a file with a large header. # This is line 711 of a file with a large header. # This is line 712 of a file with a large header. # This is line 713 of a file with a large header. # This is line 714 of a file with a large header. # This is line 715 of a file with a large header. # This is line 716 of a file with a large header. # This is line 717 of a file with a large header. # This is line 718 of a file with a large header. # This is line 719 of a file with a large header. # This is line 720 of a file with a large header. # This is line 721 of a file with a large header. # This is line 722 of a file with a large header. # This is line 723 of a file with a large header. # This is line 724 of a file with a large header. # This is line 725 of a file with a large header. # This is line 726 of a file with a large header. # This is line 727 of a file with a large header. # This is line 728 of a file with a large header. # This is line 729 of a file with a large header. # This is line 730 of a file with a large header. # This is line 731 of a file with a large header. # This is line 732 of a file with a large header. # This is line 733 of a file with a large header. # This is line 734 of a file with a large header. # This is line 735 of a file with a large header. # This is line 736 of a file with a large header. # This is line 737 of a file with a large header. # This is line 738 of a file with a large header. # This is line 739 of a file with a large header. # This is line 740 of a file with a large header. # This is line 741 of a file with a large header. # This is line 742 of a file with a large header. # This is line 743 of a file with a large header. # This is line 744 of a file with a large header. # This is line 745 of a file with a large header. # This is line 746 of a file with a large header. # This is line 747 of a file with a large header. # This is line 748 of a file with a large header. # This is line 749 of a file with a large header. # This is line 750 of a file with a large header. # This is line 751 of a file with a large header. # This is line 752 of a file with a large header. # This is line 753 of a file with a large header. # This is line 754 of a file with a large header. # This is line 755 of a file with a large header. # This is line 756 of a file with a large header. # This is line 757 of a file with a large header. # This is line 758 of a file with a large header. # This is line 759 of a file with a large header. # This is line 760 of a file with a large header. # This is line 761 of a file with a large header. # This is line 762 of a file with a large header. # This is line 763 of a file with a large header. # This is line 764 of a file with a large header. # This is line 765 of a file with a large header. # This is line 766 of a file with a large header. # This is line 767 of a file with a large header. # This is line 768 of a file with a large header. # This is line 769 of a file with a large header. # This is line 770 of a file with a large header. # This is line 771 of a file with a large header. # This is line 772 of a file with a large header. # This is line 773 of a file with a large header. # This is line 774 of a file with a large header. # This is line 775 of a file with a large header. # This is line 776 of a file with a large header. # This is line 777 of a file with a large header. # This is line 778 of a file with a large header. # This is line 779 of a file with a large header. # This is line 780 of a file with a large header. # This is line 781 of a file with a large header. # This is line 782 of a file with a large header. # This is line 783 of a file with a large header. # This is line 784 of a file with a large header. # This is line 785 of a file with a large header. # This is line 786 of a file with a large header. # This is line 787 of a file with a large header. # This is line 788 of a file with a large header. # This is line 789 of a file with a large header. # This is line 790 of a file with a large header. # This is line 791 of a file with a large header. # This is line 792 of a file with a large header. # This is line 793 of a file with a large header. # This is line 794 of a file with a large header. # This is line 795 of a file with a large header. # This is line 796 of a file with a large header. # This is line 797 of a file with a large header. # This is line 798 of a file with a large header. # This is line 799 of a file with a large header. # This is line 800 of a file with a large header. # This is line 801 of a file with a large header. # This is line 802 of a file with a large header. # This is line 803 of a file with a large header. # This is line 804 of a file with a large header. # This is line 805 of a file with a large header. # This is line 806 of a file with a large header. # This is line 807 of a file with a large header. # This is line 808 of a file with a large header. # This is line 809 of a file with a large header. # This is line 810 of a file with a large header. # This is line 811 of a file with a large header. # This is line 812 of a file with a large header. # This is line 813 of a file with a large header. # This is line 814 of a file with a large header. # This is line 815 of a file with a large header. # This is line 816 of a file with a large header. # This is line 817 of a file with a large header. # This is line 818 of a file with a large header. # This is line 819 of a file with a large header. # This is line 820 of a file with a large header. # This is line 821 of a file with a large header. # This is line 822 of a file with a large header. # This is line 823 of a file with a large header. # This is line 824 of a file with a large header. # This is line 825 of a file with a large header. # This is line 826 of a file with a large header. # This is line 827 of a file with a large header. # This is line 828 of a file with a large header. # This is line 829 of a file with a large header. # This is line 830 of a file with a large header. # This is line 831 of a file with a large header. # This is line 832 of a file with a large header. # This is line 833 of a file with a large header. # This is line 834 of a file with a large header. # This is line 835 of a file with a large header. # This is line 836 of a file with a large header. # This is line 837 of a file with a large header. # This is line 838 of a file with a large header. # This is line 839 of a file with a large header. # This is line 840 of a file with a large header. # This is line 841 of a file with a large header. # This is line 842 of a file with a large header. # This is line 843 of a file with a large header. # This is line 844 of a file with a large header. # This is line 845 of a file with a large header. # This is line 846 of a file with a large header. # This is line 847 of a file with a large header. # This is line 848 of a file with a large header. # This is line 849 of a file with a large header. # This is line 850 of a file with a large header. # This is line 851 of a file with a large header. # This is line 852 of a file with a large header. # This is line 853 of a file with a large header. # This is line 854 of a file with a large header. # This is line 855 of a file with a large header. # This is line 856 of a file with a large header. # This is line 857 of a file with a large header. # This is line 858 of a file with a large header. # This is line 859 of a file with a large header. # This is line 860 of a file with a large header. # This is line 861 of a file with a large header. # This is line 862 of a file with a large header. # This is line 863 of a file with a large header. # This is line 864 of a file with a large header. # This is line 865 of a file with a large header. # This is line 866 of a file with a large header. # This is line 867 of a file with a large header. # This is line 868 of a file with a large header. # This is line 869 of a file with a large header. # This is line 870 of a file with a large header. # This is line 871 of a file with a large header. # This is line 872 of a file with a large header. # This is line 873 of a file with a large header. # This is line 874 of a file with a large header. # This is line 875 of a file with a large header. # This is line 876 of a file with a large header. # This is line 877 of a file with a large header. # This is line 878 of a file with a large header. # This is line 879 of a file with a large header. # This is line 880 of a file with a large header. # This is line 881 of a file with a large header. # This is line 882 of a file with a large header. # This is line 883 of a file with a large header. # This is line 884 of a file with a large header. # This is line 885 of a file with a large header. # This is line 886 of a file with a large header. # This is line 887 of a file with a large header. # This is line 888 of a file with a large header. # This is line 889 of a file with a large header. # This is line 890 of a file with a large header. # This is line 891 of a file with a large header. # This is line 892 of a file with a large header. # This is line 893 of a file with a large header. # This is line 894 of a file with a large header. # This is line 895 of a file with a large header. # This is line 896 of a file with a large header. # This is line 897 of a file with a large header. # This is line 898 of a file with a large header. # This is line 899 of a file with a large header. # This is line 900 of a file with a large header. # This is line 901 of a file with a large header. # This is line 902 of a file with a large header. # This is line 903 of a file with a large header. # This is line 904 of a file with a large header. # This is line 905 of a file with a large header. # This is line 906 of a file with a large header. # This is line 907 of a file with a large header. # This is line 908 of a file with a large header. # This is line 909 of a file with a large header. # This is line 910 of a file with a large header. # This is line 911 of a file with a large header. # This is line 912 of a file with a large header. # This is line 913 of a file with a large header. # This is line 914 of a file with a large header. # This is line 915 of a file with a large header. # This is line 916 of a file with a large header. # This is line 917 of a file with a large header. # This is line 918 of a file with a large header. # This is line 919 of a file with a large header. # This is line 920 of a file with a large header. # This is line 921 of a file with a large header. # This is line 922 of a file with a large header. # This is line 923 of a file with a large header. # This is line 924 of a file with a large header. # This is line 925 of a file with a large header. # This is line 926 of a file with a large header. # This is line 927 of a file with a large header. # This is line 928 of a file with a large header. # This is line 929 of a file with a large header. # This is line 930 of a file with a large header. # This is line 931 of a file with a large header. # This is line 932 of a file with a large header. # This is line 933 of a file with a large header. # This is line 934 of a file with a large header. # This is line 935 of a file with a large header. # This is line 936 of a file with a large header. # This is line 937 of a file with a large header. # This is line 938 of a file with a large header. # This is line 939 of a file with a large header. # This is line 940 of a file with a large header. # This is line 941 of a file with a large header. # This is line 942 of a file with a large header. # This is line 943 of a file with a large header. # This is line 944 of a file with a large header. # This is line 945 of a file with a large header. # This is line 946 of a file with a large header. # This is line 947 of a file with a large header. # This is line 948 of a file with a large header. # This is line 949 of a file with a large header. # This is line 950 of a file with a large header. # This is line 951 of a file with a large header. # This is line 952 of a file with a large header. # This is line 953 of a file with a large header. # This is line 954 of a file with a large header. # This is line 955 of a file with a large header. # This is line 956 of a file with a large header. # This is line 957 of a file with a large header. # This is line 958 of a file with a large header. # This is line 959 of a file with a large header. # This is line 960 of a file with a large header. # This is line 961 of a file with a large header. # This is line 962 of a file with a large header. # This is line 963 of a file with a large header. # This is line 964 of a file with a large header. # This is line 965 of a file with a large header. # This is line 966 of a file with a large header. # This is line 967 of a file with a large header. # This is line 968 of a file with a large header. # This is line 969 of a file with a large header. # This is line 970 of a file with a large header. # This is line 971 of a file with a large header. # This is line 972 of a file with a large header. # This is line 973 of a file with a large header. # This is line 974 of a file with a large header. # This is line 975 of a file with a large header. # This is line 976 of a file with a large header. # This is line 977 of a file with a large header. # This is line 978 of a file with a large header. # This is line 979 of a file with a large header. # This is line 980 of a file with a large header. # This is line 981 of a file with a large header. # This is line 982 of a file with a large header. # This is line 983 of a file with a large header. # This is line 984 of a file with a large header. # This is line 985 of a file with a large header. # This is line 986 of a file with a large header. # This is line 987 of a file with a large header. # This is line 988 of a file with a large header. # This is line 989 of a file with a large header. # This is line 990 of a file with a large header. # This is line 991 of a file with a large header. # This is line 992 of a file with a large header. # This is line 993 of a file with a large header. # This is line 994 of a file with a large header. # This is line 995 of a file with a large header. # This is line 996 of a file with a large header. # This is line 997 of a file with a large header. # This is line 998 of a file with a large header. # This is line 999 of a file with a large header. # This is line 1000 of a file with a large header. # This is line 1001 of a file with a large header. # This is line 1002 of a file with a large header. # This is line 1003 of a file with a large header. # This is line 1004 of a file with a large header. # This is line 1005 of a file with a large header. # This is line 1006 of a file with a large header. # This is line 1007 of a file with a large header. # This is line 1008 of a file with a large header. # This is line 1009 of a file with a large header. # This is line 1010 of a file with a large header. # This is line 1011 of a file with a large header. # This is line 1012 of a file with a large header. # This is line 1013 of a file with a large header. # This is line 1014 of a file with a large header. # This is line 1015 of a file with a large header. # This is line 1016 of a file with a large header. # This is line 1017 of a file with a large header. # This is line 1018 of a file with a large header. # This is line 1019 of a file with a large header. # This is line 1020 of a file with a large header. # This is line 1021 of a file with a large header. # This is line 1022 of a file with a large header. # This is line 1023 of a file with a large header. # This is line 1024 of a file with a large header. # This is line 1025 of a file with a large header. # This is line 1026 of a file with a large header. # This is line 1027 of a file with a large header. # This is line 1028 of a file with a large header. # This is line 1029 of a file with a large header. # This is line 1030 of a file with a large header. # This is line 1031 of a file with a large header. # This is line 1032 of a file with a large header. # This is line 1033 of a file with a large header. # This is line 1034 of a file with a large header. # This is line 1035 of a file with a large header. # This is line 1036 of a file with a large header. # This is line 1037 of a file with a large header. # This is line 1038 of a file with a large header. # This is line 1039 of a file with a large header. # This is line 1040 of a file with a large header. # This is line 1041 of a file with a large header. # This is line 1042 of a file with a large header. # This is line 1043 of a file with a large header. # This is line 1044 of a file with a large header. # This is line 1045 of a file with a large header. # This is line 1046 of a file with a large header. # This is line 1047 of a file with a large header. # This is line 1048 of a file with a large header. # This is line 1049 of a file with a large header. # This is line 1050 of a file with a large header. # This is line 1051 of a file with a large header. # This is line 1052 of a file with a large header. # This is line 1053 of a file with a large header. # This is line 1054 of a file with a large header. # This is line 1055 of a file with a large header. # This is line 1056 of a file with a large header. # This is line 1057 of a file with a large header. # This is line 1058 of a file with a large header. # This is line 1059 of a file with a large header. # This is line 1060 of a file with a large header. # This is line 1061 of a file with a large header. # This is line 1062 of a file with a large header. # This is line 1063 of a file with a large header. # This is line 1064 of a file with a large header. # This is line 1065 of a file with a large header. # This is line 1066 of a file with a large header. # This is line 1067 of a file with a large header. # This is line 1068 of a file with a large header. # This is line 1069 of a file with a large header. # This is line 1070 of a file with a large header. # This is line 1071 of a file with a large header. # This is line 1072 of a file with a large header. # This is line 1073 of a file with a large header. # This is line 1074 of a file with a large header. # This is line 1075 of a file with a large header. # This is line 1076 of a file with a large header. # This is line 1077 of a file with a large header. # This is line 1078 of a file with a large header. # This is line 1079 of a file with a large header. # This is line 1080 of a file with a large header. # This is line 1081 of a file with a large header. # This is line 1082 of a file with a large header. # This is line 1083 of a file with a large header. # This is line 1084 of a file with a large header. # This is line 1085 of a file with a large header. # This is line 1086 of a file with a large header. # This is line 1087 of a file with a large header. # This is line 1088 of a file with a large header. # This is line 1089 of a file with a large header. # This is line 1090 of a file with a large header. # This is line 1091 of a file with a large header. # This is line 1092 of a file with a large header. # This is line 1093 of a file with a large header. # This is line 1094 of a file with a large header. # This is line 1095 of a file with a large header. # This is line 1096 of a file with a large header. # This is line 1097 of a file with a large header. # This is line 1098 of a file with a large header. # This is line 1099 of a file with a large header. # This is line 1100 of a file with a large header. # This is line 1101 of a file with a large header. # This is line 1102 of a file with a large header. # This is line 1103 of a file with a large header. # This is line 1104 of a file with a large header. # This is line 1105 of a file with a large header. # This is line 1106 of a file with a large header. # This is line 1107 of a file with a large header. # This is line 1108 of a file with a large header. # This is line 1109 of a file with a large header. # This is line 1110 of a file with a large header. # This is line 1111 of a file with a large header. # This is line 1112 of a file with a large header. # This is line 1113 of a file with a large header. # This is line 1114 of a file with a large header. # This is line 1115 of a file with a large header. # This is line 1116 of a file with a large header. # This is line 1117 of a file with a large header. # This is line 1118 of a file with a large header. # This is line 1119 of a file with a large header. # This is line 1120 of a file with a large header. # This is line 1121 of a file with a large header. # This is line 1122 of a file with a large header. # This is line 1123 of a file with a large header. # This is line 1124 of a file with a large header. # This is line 1125 of a file with a large header. # This is line 1126 of a file with a large header. # This is line 1127 of a file with a large header. # This is line 1128 of a file with a large header. # This is line 1129 of a file with a large header. # This is line 1130 of a file with a large header. # This is line 1131 of a file with a large header. # This is line 1132 of a file with a large header. # This is line 1133 of a file with a large header. # This is line 1134 of a file with a large header. # This is line 1135 of a file with a large header. # This is line 1136 of a file with a large header. # This is line 1137 of a file with a large header. # This is line 1138 of a file with a large header. # This is line 1139 of a file with a large header. # This is line 1140 of a file with a large header. # This is line 1141 of a file with a large header. # This is line 1142 of a file with a large header. # This is line 1143 of a file with a large header. # This is line 1144 of a file with a large header. # This is line 1145 of a file with a large header. # This is line 1146 of a file with a large header. # This is line 1147 of a file with a large header. # This is line 1148 of a file with a large header. # This is line 1149 of a file with a large header. # This is line 1150 of a file with a large header. # This is line 1151 of a file with a large header. # This is line 1152 of a file with a large header. # This is line 1153 of a file with a large header. # This is line 1154 of a file with a large header. # This is line 1155 of a file with a large header. # This is line 1156 of a file with a large header. # This is line 1157 of a file with a large header. # This is line 1158 of a file with a large header. # This is line 1159 of a file with a large header. # This is line 1160 of a file with a large header. # This is line 1161 of a file with a large header. # This is line 1162 of a file with a large header. # This is line 1163 of a file with a large header. # This is line 1164 of a file with a large header. # This is line 1165 of a file with a large header. # This is line 1166 of a file with a large header. # This is line 1167 of a file with a large header. # This is line 1168 of a file with a large header. # This is line 1169 of a file with a large header. # This is line 1170 of a file with a large header. # This is line 1171 of a file with a large header. # This is line 1172 of a file with a large header. # This is line 1173 of a file with a large header. # This is line 1174 of a file with a large header. # This is line 1175 of a file with a large header. # This is line 1176 of a file with a large header. # This is line 1177 of a file with a large header. # This is line 1178 of a file with a large header. # This is line 1179 of a file with a large header. # This is line 1180 of a file with a large header. # This is line 1181 of a file with a large header. # This is line 1182 of a file with a large header. # This is line 1183 of a file with a large header. # This is line 1184 of a file with a large header. # This is line 1185 of a file with a large header. # This is line 1186 of a file with a large header. # This is line 1187 of a file with a large header. # This is line 1188 of a file with a large header. # This is line 1189 of a file with a large header. # This is line 1190 of a file with a large header. # This is line 1191 of a file with a large header. # This is line 1192 of a file with a large header. # This is line 1193 of a file with a large header. # This is line 1194 of a file with a large header. # This is line 1195 of a file with a large header. # This is line 1196 of a file with a large header. # This is line 1197 of a file with a large header. # This is line 1198 of a file with a large header. # This is line 1199 of a file with a large header. # This is line 1200 of a file with a large header. # This is line 1201 of a file with a large header. # This is line 1202 of a file with a large header. # This is line 1203 of a file with a large header. # This is line 1204 of a file with a large header. # This is line 1205 of a file with a large header. # This is line 1206 of a file with a large header. # This is line 1207 of a file with a large header. # This is line 1208 of a file with a large header. # This is line 1209 of a file with a large header. # This is line 1210 of a file with a large header. # This is line 1211 of a file with a large header. # This is line 1212 of a file with a large header. # This is line 1213 of a file with a large header. # This is line 1214 of a file with a large header. # This is line 1215 of a file with a large header. # This is line 1216 of a file with a large header. # This is line 1217 of a file with a large header. # This is line 1218 of a file with a large header. # This is line 1219 of a file with a large header. # This is line 1220 of a file with a large header. # This is line 1221 of a file with a large header. # This is line 1222 of a file with a large header. # This is line 1223 of a file with a large header. # This is line 1224 of a file with a large header. # This is line 1225 of a file with a large header. # This is line 1226 of a file with a large header. # This is line 1227 of a file with a large header. # This is line 1228 of a file with a large header. # This is line 1229 of a file with a large header. # This is line 1230 of a file with a large header. # This is line 1231 of a file with a large header. # This is line 1232 of a file with a large header. # This is line 1233 of a file with a large header. # This is line 1234 of a file with a large header. # This is line 1235 of a file with a large header. # This is line 1236 of a file with a large header. # This is line 1237 of a file with a large header. # This is line 1238 of a file with a large header. # This is line 1239 of a file with a large header. # This is line 1240 of a file with a large header. # This is line 1241 of a file with a large header. # This is line 1242 of a file with a large header. # This is line 1243 of a file with a large header. # This is line 1244 of a file with a large header. # This is line 1245 of a file with a large header. # This is line 1246 of a file with a large header. # This is line 1247 of a file with a large header. # This is line 1248 of a file with a large header. # This is line 1249 of a file with a large header. # This is line 1250 of a file with a large header. # This is line 1251 of a file with a large header. # This is line 1252 of a file with a large header. # This is line 1253 of a file with a large header. # This is line 1254 of a file with a large header. # This is line 1255 of a file with a large header. # This is line 1256 of a file with a large header. # This is line 1257 of a file with a large header. # This is line 1258 of a file with a large header. # This is line 1259 of a file with a large header. # This is line 1260 of a file with a large header. # This is line 1261 of a file with a large header. # This is line 1262 of a file with a large header. # This is line 1263 of a file with a large header. # This is line 1264 of a file with a large header. # This is line 1265 of a file with a large header. # This is line 1266 of a file with a large header. # This is line 1267 of a file with a large header. # This is line 1268 of a file with a large header. # This is line 1269 of a file with a large header. # This is line 1270 of a file with a large header. # This is line 1271 of a file with a large header. # This is line 1272 of a file with a large header. # This is line 1273 of a file with a large header. # This is line 1274 of a file with a large header. # This is line 1275 of a file with a large header. # This is line 1276 of a file with a large header. # This is line 1277 of a file with a large header. # This is line 1278 of a file with a large header. # This is line 1279 of a file with a large header. # This is line 1280 of a file with a large header. # This is line 1281 of a file with a large header. # This is line 1282 of a file with a large header. # This is line 1283 of a file with a large header. # This is line 1284 of a file with a large header. # This is line 1285 of a file with a large header. # This is line 1286 of a file with a large header. # This is line 1287 of a file with a large header. # This is line 1288 of a file with a large header. # This is line 1289 of a file with a large header. # This is line 1290 of a file with a large header. # This is line 1291 of a file with a large header. # This is line 1292 of a file with a large header. # This is line 1293 of a file with a large header. # This is line 1294 of a file with a large header. # This is line 1295 of a file with a large header. # This is line 1296 of a file with a large header. # This is line 1297 of a file with a large header. # This is line 1298 of a file with a large header. # This is line 1299 of a file with a large header. # This is line 1300 of a file with a large header. # This is line 1301 of a file with a large header. # This is line 1302 of a file with a large header. # This is line 1303 of a file with a large header. # This is line 1304 of a file with a large header. # This is line 1305 of a file with a large header. # This is line 1306 of a file with a large header. # This is line 1307 of a file with a large header. # This is line 1308 of a file with a large header. # This is line 1309 of a file with a large header. # This is line 1310 of a file with a large header. # This is line 1311 of a file with a large header. # This is line 1312 of a file with a large header. # This is line 1313 of a file with a large header. # This is line 1314 of a file with a large header. # This is line 1315 of a file with a large header. # This is line 1316 of a file with a large header. # This is line 1317 of a file with a large header. # This is line 1318 of a file with a large header. # This is line 1319 of a file with a large header. # This is line 1320 of a file with a large header. # This is line 1321 of a file with a large header. # This is line 1322 of a file with a large header. # This is line 1323 of a file with a large header. # This is line 1324 of a file with a large header. # This is line 1325 of a file with a large header. # This is line 1326 of a file with a large header. # This is line 1327 of a file with a large header. # This is line 1328 of a file with a large header. # This is line 1329 of a file with a large header. # This is line 1330 of a file with a large header. # This is line 1331 of a file with a large header. # This is line 1332 of a file with a large header. # This is line 1333 of a file with a large header. # This is line 1334 of a file with a large header. # This is line 1335 of a file with a large header. # This is line 1336 of a file with a large header. # This is line 1337 of a file with a large header. # This is line 1338 of a file with a large header. # This is line 1339 of a file with a large header. # This is line 1340 of a file with a large header. # This is line 1341 of a file with a large header. # This is line 1342 of a file with a large header. # This is line 1343 of a file with a large header. # This is line 1344 of a file with a large header. # This is line 1345 of a file with a large header. # This is line 1346 of a file with a large header. # This is line 1347 of a file with a large header. # This is line 1348 of a file with a large header. # This is line 1349 of a file with a large header. # This is line 1350 of a file with a large header. # This is line 1351 of a file with a large header. # This is line 1352 of a file with a large header. # This is line 1353 of a file with a large header. # This is line 1354 of a file with a large header. # This is line 1355 of a file with a large header. # This is line 1356 of a file with a large header. # This is line 1357 of a file with a large header. # This is line 1358 of a file with a large header. # This is line 1359 of a file with a large header. # This is line 1360 of a file with a large header. # This is line 1361 of a file with a large header. # This is line 1362 of a file with a large header. # This is line 1363 of a file with a large header. # This is line 1364 of a file with a large header. # This is line 1365 of a file with a large header. # This is line 1366 of a file with a large header. # This is line 1367 of a file with a large header. # This is line 1368 of a file with a large header. # This is line 1369 of a file with a large header. # This is line 1370 of a file with a large header. # This is line 1371 of a file with a large header. # This is line 1372 of a file with a large header. # This is line 1373 of a file with a large header. # This is line 1374 of a file with a large header. # This is line 1375 of a file with a large header. # This is line 1376 of a file with a large header. # This is line 1377 of a file with a large header. # This is line 1378 of a file with a large header. # This is line 1379 of a file with a large header. # This is line 1380 of a file with a large header. # This is line 1381 of a file with a large header. # This is line 1382 of a file with a large header. # This is line 1383 of a file with a large header. # This is line 1384 of a file with a large header. # This is line 1385 of a file with a large header. # This is line 1386 of a file with a large header. # This is line 1387 of a file with a large header. # This is line 1388 of a file with a large header. # This is line 1389 of a file with a large header. # This is line 1390 of a file with a large header. # This is line 1391 of a file with a large header. # This is line 1392 of a file with a large header. # This is line 1393 of a file with a large header. # This is line 1394 of a file with a large header. # This is line 1395 of a file with a large header. # This is line 1396 of a file with a large header. # This is line 1397 of a file with a large header. # This is line 1398 of a file with a large header. # This is line 1399 of a file with a large header. # This is line 1400 of a file with a large header. # This is line 1401 of a file with a large header. # This is line 1402 of a file with a large header. # This is line 1403 of a file with a large header. # This is line 1404 of a file with a large header. # This is line 1405 of a file with a large header. # This is line 1406 of a file with a large header. # This is line 1407 of a file with a large header. # This is line 1408 of a file with a large header. # This is line 1409 of a file with a large header. # This is line 1410 of a file with a large header. # This is line 1411 of a file with a large header. # This is line 1412 of a file with a large header. # This is line 1413 of a file with a large header. # This is line 1414 of a file with a large header. # This is line 1415 of a file with a large header. # This is line 1416 of a file with a large header. # This is line 1417 of a file with a large header. # This is line 1418 of a file with a large header. # This is line 1419 of a file with a large header. # This is line 1420 of a file with a large header. # This is line 1421 of a file with a large header. # This is line 1422 of a file with a large header. # This is line 1423 of a file with a large header. # This is line 1424 of a file with a large header. # This is line 1425 of a file with a large header. # This is line 1426 of a file with a large header. # This is line 1427 of a file with a large header. # This is line 1428 of a file with a large header. # This is line 1429 of a file with a large header. # This is line 1430 of a file with a large header. # This is line 1431 of a file with a large header. # This is line 1432 of a file with a large header. # This is line 1433 of a file with a large header. # This is line 1434 of a file with a large header. # This is line 1435 of a file with a large header. # This is line 1436 of a file with a large header. # This is line 1437 of a file with a large header. # This is line 1438 of a file with a large header. # This is line 1439 of a file with a large header. # This is line 1440 of a file with a large header. # This is line 1441 of a file with a large header. # This is line 1442 of a file with a large header. # This is line 1443 of a file with a large header. # This is line 1444 of a file with a large header. # This is line 1445 of a file with a large header. # This is line 1446 of a file with a large header. # This is line 1447 of a file with a large header. # This is line 1448 of a file with a large header. # This is line 1449 of a file with a large header. # This is line 1450 of a file with a large header. # This is line 1451 of a file with a large header. # This is line 1452 of a file with a large header. # This is line 1453 of a file with a large header. # This is line 1454 of a file with a large header. # This is line 1455 of a file with a large header. # This is line 1456 of a file with a large header. # This is line 1457 of a file with a large header. # This is line 1458 of a file with a large header. # This is line 1459 of a file with a large header. # This is line 1460 of a file with a large header. # This is line 1461 of a file with a large header. # This is line 1462 of a file with a large header. # This is line 1463 of a file with a large header. # This is line 1464 of a file with a large header. # This is line 1465 of a file with a large header. # This is line 1466 of a file with a large header. # This is line 1467 of a file with a large header. # This is line 1468 of a file with a large header. # This is line 1469 of a file with a large header. # This is line 1470 of a file with a large header. # This is line 1471 of a file with a large header. # This is line 1472 of a file with a large header. # This is line 1473 of a file with a large header. # This is line 1474 of a file with a large header. # This is line 1475 of a file with a large header. # This is line 1476 of a file with a large header. # This is line 1477 of a file with a large header. # This is line 1478 of a file with a large header. # This is line 1479 of a file with a large header. # This is line 1480 of a file with a large header. # This is line 1481 of a file with a large header. # This is line 1482 of a file with a large header. # This is line 1483 of a file with a large header. # This is line 1484 of a file with a large header. # This is line 1485 of a file with a large header. # This is line 1486 of a file with a large header. # This is line 1487 of a file with a large header. # This is line 1488 of a file with a large header. # This is line 1489 of a file with a large header. # This is line 1490 of a file with a large header. # This is line 1491 of a file with a large header. # This is line 1492 of a file with a large header. # This is line 1493 of a file with a large header. # This is line 1494 of a file with a large header. # This is line 1495 of a file with a large header. # This is line 1496 of a file with a large header. # This is line 1497 of a file with a large header. # This is line 1498 of a file with a large header. # This is line 1499 of a file with a large header. # This is line 1500 of a file with a large header. # This is line 1501 of a file with a large header. # This is line 1502 of a file with a large header. # This is line 1503 of a file with a large header. # This is line 1504 of a file with a large header. # This is line 1505 of a file with a large header. # This is line 1506 of a file with a large header. # This is line 1507 of a file with a large header. # This is line 1508 of a file with a large header. # This is line 1509 of a file with a large header. # This is line 1510 of a file with a large header. # This is line 1511 of a file with a large header. # This is line 1512 of a file with a large header. # This is line 1513 of a file with a large header. # This is line 1514 of a file with a large header. # This is line 1515 of a file with a large header. # This is line 1516 of a file with a large header. # This is line 1517 of a file with a large header. # This is line 1518 of a file with a large header. # This is line 1519 of a file with a large header. # This is line 1520 of a file with a large header. # This is line 1521 of a file with a large header. # This is line 1522 of a file with a large header. # This is line 1523 of a file with a large header. # This is line 1524 of a file with a large header. # This is line 1525 of a file with a large header. # This is line 1526 of a file with a large header. # This is line 1527 of a file with a large header. # This is line 1528 of a file with a large header. # This is line 1529 of a file with a large header. # This is line 1530 of a file with a large header. # This is line 1531 of a file with a large header. # This is line 1532 of a file with a large header. # This is line 1533 of a file with a large header. # This is line 1534 of a file with a large header. # This is line 1535 of a file with a large header. # This is line 1536 of a file with a large header. # This is line 1537 of a file with a large header. # This is line 1538 of a file with a large header. # This is line 1539 of a file with a large header. # This is line 1540 of a file with a large header. # This is line 1541 of a file with a large header. # This is line 1542 of a file with a large header. # This is line 1543 of a file with a large header. # This is line 1544 of a file with a large header. # This is line 1545 of a file with a large header. # This is line 1546 of a file with a large header. # This is line 1547 of a file with a large header. # This is line 1548 of a file with a large header. # This is line 1549 of a file with a large header. # This is line 1550 of a file with a large header. # This is line 1551 of a file with a large header. # This is line 1552 of a file with a large header. # This is line 1553 of a file with a large header. # This is line 1554 of a file with a large header. # This is line 1555 of a file with a large header. # This is line 1556 of a file with a large header. # This is line 1557 of a file with a large header. # This is line 1558 of a file with a large header. # This is line 1559 of a file with a large header. # This is line 1560 of a file with a large header. # This is line 1561 of a file with a large header. # This is line 1562 of a file with a large header. # This is line 1563 of a file with a large header. # This is line 1564 of a file with a large header. # This is line 1565 of a file with a large header. # This is line 1566 of a file with a large header. # This is line 1567 of a file with a large header. # This is line 1568 of a file with a large header. # This is line 1569 of a file with a large header. # This is line 1570 of a file with a large header. # This is line 1571 of a file with a large header. # This is line 1572 of a file with a large header. # This is line 1573 of a file with a large header. # This is line 1574 of a file with a large header. # This is line 1575 of a file with a large header. # This is line 1576 of a file with a large header. # This is line 1577 of a file with a large header. # This is line 1578 of a file with a large header. # This is line 1579 of a file with a large header. # This is line 1580 of a file with a large header. # This is line 1581 of a file with a large header. # This is line 1582 of a file with a large header. # This is line 1583 of a file with a large header. # This is line 1584 of a file with a large header. # This is line 1585 of a file with a large header. # This is line 1586 of a file with a large header. # This is line 1587 of a file with a large header. # This is line 1588 of a file with a large header. # This is line 1589 of a file with a large header. # This is line 1590 of a file with a large header. # This is line 1591 of a file with a large header. # This is line 1592 of a file with a large header. # This is line 1593 of a file with a large header. # This is line 1594 of a file with a large header. # This is line 1595 of a file with a large header. # This is line 1596 of a file with a large header. # This is line 1597 of a file with a large header. # This is line 1598 of a file with a large header. # This is line 1599 of a file with a large header. # This is line 1600 of a file with a large header. # This is line 1601 of a file with a large header. # This is line 1602 of a file with a large header. # This is line 1603 of a file with a large header. # This is line 1604 of a file with a large header. # This is line 1605 of a file with a large header. # This is line 1606 of a file with a large header. # This is line 1607 of a file with a large header. # This is line 1608 of a file with a large header. # This is line 1609 of a file with a large header. # This is line 1610 of a file with a large header. # This is line 1611 of a file with a large header. # This is line 1612 of a file with a large header. # This is line 1613 of a file with a large header. # This is line 1614 of a file with a large header. # This is line 1615 of a file with a large header. # This is line 1616 of a file with a large header. # This is line 1617 of a file with a large header. # This is line 1618 of a file with a large header. # This is line 1619 of a file with a large header. # This is line 1620 of a file with a large header. # This is line 1621 of a file with a large header. # This is line 1622 of a file with a large header. # This is line 1623 of a file with a large header. # This is line 1624 of a file with a large header. # This is line 1625 of a file with a large header. # This is line 1626 of a file with a large header. # This is line 1627 of a file with a large header. # This is line 1628 of a file with a large header. # This is line 1629 of a file with a large header. # This is line 1630 of a file with a large header. # This is line 1631 of a file with a large header. # This is line 1632 of a file with a large header. # This is line 1633 of a file with a large header. # This is line 1634 of a file with a large header. # This is line 1635 of a file with a large header. # This is line 1636 of a file with a large header. # This is line 1637 of a file with a large header. # This is line 1638 of a file with a large header. # This is line 1639 of a file with a large header. # This is line 1640 of a file with a large header. # This is line 1641 of a file with a large header. # This is line 1642 of a file with a large header. # This is line 1643 of a file with a large header. # This is line 1644 of a file with a large header. # This is line 1645 of a file with a large header. # This is line 1646 of a file with a large header. # This is line 1647 of a file with a large header. # This is line 1648 of a file with a large header. # This is line 1649 of a file with a large header. # This is line 1650 of a file with a large header. # This is line 1651 of a file with a large header. # This is line 1652 of a file with a large header. # This is line 1653 of a file with a large header. # This is line 1654 of a file with a large header. # This is line 1655 of a file with a large header. # This is line 1656 of a file with a large header. # This is line 1657 of a file with a large header. # This is line 1658 of a file with a large header. # This is line 1659 of a file with a large header. # This is line 1660 of a file with a large header. # This is line 1661 of a file with a large header. # This is line 1662 of a file with a large header. # This is line 1663 of a file with a large header. # This is line 1664 of a file with a large header. # This is line 1665 of a file with a large header. # This is line 1666 of a file with a large header. # This is line 1667 of a file with a large header. # This is line 1668 of a file with a large header. # This is line 1669 of a file with a large header. # This is line 1670 of a file with a large header. # This is line 1671 of a file with a large header. # This is line 1672 of a file with a large header. # This is line 1673 of a file with a large header. # This is line 1674 of a file with a large header. # This is line 1675 of a file with a large header. # This is line 1676 of a file with a large header. # This is line 1677 of a file with a large header. # This is line 1678 of a file with a large header. # This is line 1679 of a file with a large header. # This is line 1680 of a file with a large header. # This is line 1681 of a file with a large header. # This is line 1682 of a file with a large header. # This is line 1683 of a file with a large header. # This is line 1684 of a file with a large header. # This is line 1685 of a file with a large header. # This is line 1686 of a file with a large header. # This is line 1687 of a file with a large header. # This is line 1688 of a file with a large header. # This is line 1689 of a file with a large header. # This is line 1690 of a file with a large header. # This is line 1691 of a file with a large header. # This is line 1692 of a file with a large header. # This is line 1693 of a file with a large header. # This is line 1694 of a file with a large header. # This is line 1695 of a file with a large header. # This is line 1696 of a file with a large header. # This is line 1697 of a file with a large header. # This is line 1698 of a file with a large header. # This is line 1699 of a file with a large header. # This is line 1700 of a file with a large header. # This is line 1701 of a file with a large header. # This is line 1702 of a file with a large header. # This is line 1703 of a file with a large header. # This is line 1704 of a file with a large header. # This is line 1705 of a file with a large header. # This is line 1706 of a file with a large header. # This is line 1707 of a file with a large header. # This is line 1708 of a file with a large header. # This is line 1709 of a file with a large header. # This is line 1710 of a file with a large header. # This is line 1711 of a file with a large header. # This is line 1712 of a file with a large header. # This is line 1713 of a file with a large header. # This is line 1714 of a file with a large header. # This is line 1715 of a file with a large header. # This is line 1716 of a file with a large header. # This is line 1717 of a file with a large header. # This is line 1718 of a file with a large header. # This is line 1719 of a file with a large header. # This is line 1720 of a file with a large header. # This is line 1721 of a file with a large header. # This is line 1722 of a file with a large header. # This is line 1723 of a file with a large header. # This is line 1724 of a file with a large header. # This is line 1725 of a file with a large header. # This is line 1726 of a file with a large header. # This is line 1727 of a file with a large header. # This is line 1728 of a file with a large header. # This is line 1729 of a file with a large header. # This is line 1730 of a file with a large header. # This is line 1731 of a file with a large header. # This is line 1732 of a file with a large header. # This is line 1733 of a file with a large header. # This is line 1734 of a file with a large header. # This is line 1735 of a file with a large header. # This is line 1736 of a file with a large header. # This is line 1737 of a file with a large header. # This is line 1738 of a file with a large header. # This is line 1739 of a file with a large header. # This is line 1740 of a file with a large header. # This is line 1741 of a file with a large header. # This is line 1742 of a file with a large header. # This is line 1743 of a file with a large header. # This is line 1744 of a file with a large header. # This is line 1745 of a file with a large header. # This is line 1746 of a file with a large header. # This is line 1747 of a file with a large header. # This is line 1748 of a file with a large header. # This is line 1749 of a file with a large header. # This is line 1750 of a file with a large header. # This is line 1751 of a file with a large header. # This is line 1752 of a file with a large header. # This is line 1753 of a file with a large header. # This is line 1754 of a file with a large header. # This is line 1755 of a file with a large header. # This is line 1756 of a file with a large header. # This is line 1757 of a file with a large header. # This is line 1758 of a file with a large header. # This is line 1759 of a file with a large header. # This is line 1760 of a file with a large header. # This is line 1761 of a file with a large header. # This is line 1762 of a file with a large header. # This is line 1763 of a file with a large header. # This is line 1764 of a file with a large header. # This is line 1765 of a file with a large header. # This is line 1766 of a file with a large header. # This is line 1767 of a file with a large header. # This is line 1768 of a file with a large header. # This is line 1769 of a file with a large header. # This is line 1770 of a file with a large header. # This is line 1771 of a file with a large header. # This is line 1772 of a file with a large header. # This is line 1773 of a file with a large header. # This is line 1774 of a file with a large header. # This is line 1775 of a file with a large header. # This is line 1776 of a file with a large header. # This is line 1777 of a file with a large header. # This is line 1778 of a file with a large header. # This is line 1779 of a file with a large header. # This is line 1780 of a file with a large header. # This is line 1781 of a file with a large header. # This is line 1782 of a file with a large header. # This is line 1783 of a file with a large header. # This is line 1784 of a file with a large header. # This is line 1785 of a file with a large header. # This is line 1786 of a file with a large header. # This is line 1787 of a file with a large header. # This is line 1788 of a file with a large header. # This is line 1789 of a file with a large header. # This is line 1790 of a file with a large header. # This is line 1791 of a file with a large header. # This is line 1792 of a file with a large header. # This is line 1793 of a file with a large header. # This is line 1794 of a file with a large header. # This is line 1795 of a file with a large header. # This is line 1796 of a file with a large header. # This is line 1797 of a file with a large header. # This is line 1798 of a file with a large header. # This is line 1799 of a file with a large header. # This is line 1800 of a file with a large header. # This is line 1801 of a file with a large header. # This is line 1802 of a file with a large header. # This is line 1803 of a file with a large header. # This is line 1804 of a file with a large header. # This is line 1805 of a file with a large header. # This is line 1806 of a file with a large header. # This is line 1807 of a file with a large header. # This is line 1808 of a file with a large header. # This is line 1809 of a file with a large header. # This is line 1810 of a file with a large header. # This is line 1811 of a file with a large header. # This is line 1812 of a file with a large header. # This is line 1813 of a file with a large header. # This is line 1814 of a file with a large header. # This is line 1815 of a file with a large header. # This is line 1816 of a file with a large header. # This is line 1817 of a file with a large header. # This is line 1818 of a file with a large header. # This is line 1819 of a file with a large header. # This is line 1820 of a file with a large header. # This is line 1821 of a file with a large header. # This is line 1822 of a file with a large header. # This is line 1823 of a file with a large header. # This is line 1824 of a file with a large header. # This is line 1825 of a file with a large header. # This is line 1826 of a file with a large header. # This is line 1827 of a file with a large header. # This is line 1828 of a file with a large header. # This is line 1829 of a file with a large header. # This is line 1830 of a file with a large header. # This is line 1831 of a file with a large header. # This is line 1832 of a file with a large header. # This is line 1833 of a file with a large header. # This is line 1834 of a file with a large header. # This is line 1835 of a file with a large header. # This is line 1836 of a file with a large header. # This is line 1837 of a file with a large header. # This is line 1838 of a file with a large header. # This is line 1839 of a file with a large header. # This is line 1840 of a file with a large header. # This is line 1841 of a file with a large header. # This is line 1842 of a file with a large header. # This is line 1843 of a file with a large header. # This is line 1844 of a file with a large header. # This is line 1845 of a file with a large header. # This is line 1846 of a file with a large header. # This is line 1847 of a file with a large header. # This is line 1848 of a file with a large header. # This is line 1849 of a file with a large header. # This is line 1850 of a file with a large header. # This is line 1851 of a file with a large header. # This is line 1852 of a file with a large header. # This is line 1853 of a file with a large header. # This is line 1854 of a file with a large header. # This is line 1855 of a file with a large header. # This is line 1856 of a file with a large header. # This is line 1857 of a file with a large header. # This is line 1858 of a file with a large header. # This is line 1859 of a file with a large header. # This is line 1860 of a file with a large header. # This is line 1861 of a file with a large header. # This is line 1862 of a file with a large header. # This is line 1863 of a file with a large header. # This is line 1864 of a file with a large header. # This is line 1865 of a file with a large header. # This is line 1866 of a file with a large header. # This is line 1867 of a file with a large header. # This is line 1868 of a file with a large header. # This is line 1869 of a file with a large header. # This is line 1870 of a file with a large header. # This is line 1871 of a file with a large header. # This is line 1872 of a file with a large header. # This is line 1873 of a file with a large header. # This is line 1874 of a file with a large header. # This is line 1875 of a file with a large header. # This is line 1876 of a file with a large header. # This is line 1877 of a file with a large header. # This is line 1878 of a file with a large header. # This is line 1879 of a file with a large header. # This is line 1880 of a file with a large header. # This is line 1881 of a file with a large header. # This is line 1882 of a file with a large header. # This is line 1883 of a file with a large header. # This is line 1884 of a file with a large header. # This is line 1885 of a file with a large header. # This is line 1886 of a file with a large header. # This is line 1887 of a file with a large header. # This is line 1888 of a file with a large header. # This is line 1889 of a file with a large header. # This is line 1890 of a file with a large header. # This is line 1891 of a file with a large header. # This is line 1892 of a file with a large header. # This is line 1893 of a file with a large header. # This is line 1894 of a file with a large header. # This is line 1895 of a file with a large header. # This is line 1896 of a file with a large header. # This is line 1897 of a file with a large header. # This is line 1898 of a file with a large header. # This is line 1899 of a file with a large header. # This is line 1900 of a file with a large header. # This is line 1901 of a file with a large header. # This is line 1902 of a file with a large header. # This is line 1903 of a file with a large header. # This is line 1904 of a file with a large header. # This is line 1905 of a file with a large header. # This is line 1906 of a file with a large header. # This is line 1907 of a file with a large header. # This is line 1908 of a file with a large header. # This is line 1909 of a file with a large header. # This is line 1910 of a file with a large header. # This is line 1911 of a file with a large header. # This is line 1912 of a file with a large header. # This is line 1913 of a file with a large header. # This is line 1914 of a file with a large header. # This is line 1915 of a file with a large header. # This is line 1916 of a file with a large header. # This is line 1917 of a file with a large header. # This is line 1918 of a file with a large header. # This is line 1919 of a file with a large header. # This is line 1920 of a file with a large header. # This is line 1921 of a file with a large header. # This is line 1922 of a file with a large header. # This is line 1923 of a file with a large header. # This is line 1924 of a file with a large header. # This is line 1925 of a file with a large header. # This is line 1926 of a file with a large header. # This is line 1927 of a file with a large header. # This is line 1928 of a file with a large header. # This is line 1929 of a file with a large header. # This is line 1930 of a file with a large header. # This is line 1931 of a file with a large header. # This is line 1932 of a file with a large header. # This is line 1933 of a file with a large header. # This is line 1934 of a file with a large header. # This is line 1935 of a file with a large header. # This is line 1936 of a file with a large header. # This is line 1937 of a file with a large header. # This is line 1938 of a file with a large header. # This is line 1939 of a file with a large header. # This is line 1940 of a file with a large header. # This is line 1941 of a file with a large header. # This is line 1942 of a file with a large header. # This is line 1943 of a file with a large header. # This is line 1944 of a file with a large header. # This is line 1945 of a file with a large header. # This is line 1946 of a file with a large header. # This is line 1947 of a file with a large header. # This is line 1948 of a file with a large header. # This is line 1949 of a file with a large header. # This is line 1950 of a file with a large header. # This is line 1951 of a file with a large header. # This is line 1952 of a file with a large header. # This is line 1953 of a file with a large header. # This is line 1954 of a file with a large header. # This is line 1955 of a file with a large header. # This is line 1956 of a file with a large header. # This is line 1957 of a file with a large header. # This is line 1958 of a file with a large header. # This is line 1959 of a file with a large header. # This is line 1960 of a file with a large header. # This is line 1961 of a file with a large header. # This is line 1962 of a file with a large header. # This is line 1963 of a file with a large header. # This is line 1964 of a file with a large header. # This is line 1965 of a file with a large header. # This is line 1966 of a file with a large header. # This is line 1967 of a file with a large header. # This is line 1968 of a file with a large header. # This is line 1969 of a file with a large header. # This is line 1970 of a file with a large header. # This is line 1971 of a file with a large header. # This is line 1972 of a file with a large header. # This is line 1973 of a file with a large header. # This is line 1974 of a file with a large header. # This is line 1975 of a file with a large header. # This is line 1976 of a file with a large header. # This is line 1977 of a file with a large header. # This is line 1978 of a file with a large header. # This is line 1979 of a file with a large header. # This is line 1980 of a file with a large header. # This is line 1981 of a file with a large header. # This is line 1982 of a file with a large header. # This is line 1983 of a file with a large header. # This is line 1984 of a file with a large header. # This is line 1985 of a file with a large header. # This is line 1986 of a file with a large header. # This is line 1987 of a file with a large header. # This is line 1988 of a file with a large header. # This is line 1989 of a file with a large header. # This is line 1990 of a file with a large header. # This is line 1991 of a file with a large header. # This is line 1992 of a file with a large header. # This is line 1993 of a file with a large header. # This is line 1994 of a file with a large header. # This is line 1995 of a file with a large header. # This is line 1996 of a file with a large header. # This is line 1997 of a file with a large header. # This is line 1998 of a file with a large header. # This is line 1999 of a file with a large header. # This is line 2000 of a file with a large header. # This is line 2001 of a file with a large header. # This is line 2002 of a file with a large header. # This is line 2003 of a file with a large header. # This is line 2004 of a file with a large header. # This is line 2005 of a file with a large header. # This is line 2006 of a file with a large header. # This is line 2007 of a file with a large header. # This is line 2008 of a file with a large header. # This is line 2009 of a file with a large header. # This is line 2010 of a file with a large header. # This is line 2011 of a file with a large header. # This is line 2012 of a file with a large header. # This is line 2013 of a file with a large header. # This is line 2014 of a file with a large header. # This is line 2015 of a file with a large header. # This is line 2016 of a file with a large header. # This is line 2017 of a file with a large header. # This is line 2018 of a file with a large header. # This is line 2019 of a file with a large header. # This is line 2020 of a file with a large header. # This is line 2021 of a file with a large header. # This is line 2022 of a file with a large header. # This is line 2023 of a file with a large header. # This is line 2024 of a file with a large header. # This is line 2025 of a file with a large header. # This is line 2026 of a file with a large header. # This is line 2027 of a file with a large header. # This is line 2028 of a file with a large header. # This is line 2029 of a file with a large header. # This is line 2030 of a file with a large header. # This is line 2031 of a file with a large header. # This is line 2032 of a file with a large header. # This is line 2033 of a file with a large header. # This is line 2034 of a file with a large header. # This is line 2035 of a file with a large header. # This is line 2036 of a file with a large header. # This is line 2037 of a file with a large header. # This is line 2038 of a file with a large header. # This is line 2039 of a file with a large header. # This is line 2040 of a file with a large header. # This is line 2041 of a file with a large header. # This is line 2042 of a file with a large header. # This is line 2043 of a file with a large header. # This is line 2044 of a file with a large header. # This is line 2045 of a file with a large header. # This is line 2046 of a file with a large header. # This is line 2047 of a file with a large header. # This is line 2048 of a file with a large header. # This is line 2049 of a file with a large header. # This is line 2050 of a file with a large header. # This is line 2051 of a file with a large header. # This is line 2052 of a file with a large header. # This is line 2053 of a file with a large header. # This is line 2054 of a file with a large header. # This is line 2055 of a file with a large header. # This is line 2056 of a file with a large header. # This is line 2057 of a file with a large header. # This is line 2058 of a file with a large header. # This is line 2059 of a file with a large header. # This is line 2060 of a file with a large header. # This is line 2061 of a file with a large header. # This is line 2062 of a file with a large header. # This is line 2063 of a file with a large header. # This is line 2064 of a file with a large header. # This is line 2065 of a file with a large header. # This is line 2066 of a file with a large header. # This is line 2067 of a file with a large header. # This is line 2068 of a file with a large header. # This is line 2069 of a file with a large header. # This is line 2070 of a file with a large header. # This is line 2071 of a file with a large header. # This is line 2072 of a file with a large header. # This is line 2073 of a file with a large header. # This is line 2074 of a file with a large header. # This is line 2075 of a file with a large header. # This is line 2076 of a file with a large header. # This is line 2077 of a file with a large header. # This is line 2078 of a file with a large header. # This is line 2079 of a file with a large header. # This is line 2080 of a file with a large header. # This is line 2081 of a file with a large header. # This is line 2082 of a file with a large header. # This is line 2083 of a file with a large header. # This is line 2084 of a file with a large header. # This is line 2085 of a file with a large header. # This is line 2086 of a file with a large header. # This is line 2087 of a file with a large header. # This is line 2088 of a file with a large header. # This is line 2089 of a file with a large header. # This is line 2090 of a file with a large header. # This is line 2091 of a file with a large header. # This is line 2092 of a file with a large header. # This is line 2093 of a file with a large header. # This is line 2094 of a file with a large header. # This is line 2095 of a file with a large header. # This is line 2096 of a file with a large header. # This is line 2097 of a file with a large header. # This is line 2098 of a file with a large header. # This is line 2099 of a file with a large header. # This is line 2100 of a file with a large header. # This is line 2101 of a file with a large header. # This is line 2102 of a file with a large header. # This is line 2103 of a file with a large header. # This is line 2104 of a file with a large header. # This is line 2105 of a file with a large header. # This is line 2106 of a file with a large header. # This is line 2107 of a file with a large header. # This is line 2108 of a file with a large header. # This is line 2109 of a file with a large header. # This is line 2110 of a file with a large header. # This is line 2111 of a file with a large header. # This is line 2112 of a file with a large header. # This is line 2113 of a file with a large header. # This is line 2114 of a file with a large header. # This is line 2115 of a file with a large header. # This is line 2116 of a file with a large header. # This is line 2117 of a file with a large header. # This is line 2118 of a file with a large header. # This is line 2119 of a file with a large header. # This is line 2120 of a file with a large header. # This is line 2121 of a file with a large header. # This is line 2122 of a file with a large header. # This is line 2123 of a file with a large header. # This is line 2124 of a file with a large header. # This is line 2125 of a file with a large header. # This is line 2126 of a file with a large header. # This is line 2127 of a file with a large header. # This is line 2128 of a file with a large header. # This is line 2129 of a file with a large header. # This is line 2130 of a file with a large header. # This is line 2131 of a file with a large header. # This is line 2132 of a file with a large header. # This is line 2133 of a file with a large header. # This is line 2134 of a file with a large header. # This is line 2135 of a file with a large header. # This is line 2136 of a file with a large header. # This is line 2137 of a file with a large header. # This is line 2138 of a file with a large header. # This is line 2139 of a file with a large header. # This is line 2140 of a file with a large header. # This is line 2141 of a file with a large header. # This is line 2142 of a file with a large header. # This is line 2143 of a file with a large header. # This is line 2144 of a file with a large header. # This is line 2145 of a file with a large header. # This is line 2146 of a file with a large header. # This is line 2147 of a file with a large header. # This is line 2148 of a file with a large header. # This is line 2149 of a file with a large header. # This is line 2150 of a file with a large header. # This is line 2151 of a file with a large header. # This is line 2152 of a file with a large header. # This is line 2153 of a file with a large header. # This is line 2154 of a file with a large header. # This is line 2155 of a file with a large header. # This is line 2156 of a file with a large header. # This is line 2157 of a file with a large header. # This is line 2158 of a file with a large header. # This is line 2159 of a file with a large header. # This is line 2160 of a file with a large header. # This is line 2161 of a file with a large header. # This is line 2162 of a file with a large header. # This is line 2163 of a file with a large header. # This is line 2164 of a file with a large header. # This is line 2165 of a file with a large header. # This is line 2166 of a file with a large header. # This is line 2167 of a file with a large header. # This is line 2168 of a file with a large header. # This is line 2169 of a file with a large header. # This is line 2170 of a file with a large header. # This is line 2171 of a file with a large header. # This is line 2172 of a file with a large header. # This is line 2173 of a file with a large header. # This is line 2174 of a file with a large header. # This is line 2175 of a file with a large header. # This is line 2176 of a file with a large header. # This is line 2177 of a file with a large header. # This is line 2178 of a file with a large header. # This is line 2179 of a file with a large header. # This is line 2180 of a file with a large header. # This is line 2181 of a file with a large header. # This is line 2182 of a file with a large header. # This is line 2183 of a file with a large header. # This is line 2184 of a file with a large header. # This is line 2185 of a file with a large header. # This is line 2186 of a file with a large header. # This is line 2187 of a file with a large header. # This is line 2188 of a file with a large header. # This is line 2189 of a file with a large header. # This is line 2190 of a file with a large header. # This is line 2191 of a file with a large header. # This is line 2192 of a file with a large header. # This is line 2193 of a file with a large header. # This is line 2194 of a file with a large header. # This is line 2195 of a file with a large header. # This is line 2196 of a file with a large header. # This is line 2197 of a file with a large header. # This is line 2198 of a file with a large header. # This is line 2199 of a file with a large header. # This is line 2200 of a file with a large header. # This is line 2201 of a file with a large header. # This is line 2202 of a file with a large header. # This is line 2203 of a file with a large header. # This is line 2204 of a file with a large header. # This is line 2205 of a file with a large header. # This is line 2206 of a file with a large header. # This is line 2207 of a file with a large header. # This is line 2208 of a file with a large header. # This is line 2209 of a file with a large header. # This is line 2210 of a file with a large header. # This is line 2211 of a file with a large header. # This is line 2212 of a file with a large header. # This is line 2213 of a file with a large header. # This is line 2214 of a file with a large header. # This is line 2215 of a file with a large header. # This is line 2216 of a file with a large header. # This is line 2217 of a file with a large header. # This is line 2218 of a file with a large header. # This is line 2219 of a file with a large header. # This is line 2220 of a file with a large header. # This is line 2221 of a file with a large header. # This is line 2222 of a file with a large header. # This is line 2223 of a file with a large header. # This is line 2224 of a file with a large header. # This is line 2225 of a file with a large header. # This is line 2226 of a file with a large header. # This is line 2227 of a file with a large header. # This is line 2228 of a file with a large header. # This is line 2229 of a file with a large header. # This is line 2230 of a file with a large header. # This is line 2231 of a file with a large header. # This is line 2232 of a file with a large header. # This is line 2233 of a file with a large header. # This is line 2234 of a file with a large header. # This is line 2235 of a file with a large header. # This is line 2236 of a file with a large header. # This is line 2237 of a file with a large header. # This is line 2238 of a file with a large header. # This is line 2239 of a file with a large header. # This is line 2240 of a file with a large header. # This is line 2241 of a file with a large header. # This is line 2242 of a file with a large header. # This is line 2243 of a file with a large header. # This is line 2244 of a file with a large header. # This is line 2245 of a file with a large header. # This is line 2246 of a file with a large header. # This is line 2247 of a file with a large header. # This is line 2248 of a file with a large header. # This is line 2249 of a file with a large header. # This is line 2250 of a file with a large header. # This is line 2251 of a file with a large header. # This is line 2252 of a file with a large header. # This is line 2253 of a file with a large header. # This is line 2254 of a file with a large header. # This is line 2255 of a file with a large header. # This is line 2256 of a file with a large header. # This is line 2257 of a file with a large header. # This is line 2258 of a file with a large header. # This is line 2259 of a file with a large header. # This is line 2260 of a file with a large header. # This is line 2261 of a file with a large header. # This is line 2262 of a file with a large header. # This is line 2263 of a file with a large header. # This is line 2264 of a file with a large header. # This is line 2265 of a file with a large header. # This is line 2266 of a file with a large header. # This is line 2267 of a file with a large header. # This is line 2268 of a file with a large header. # This is line 2269 of a file with a large header. # This is line 2270 of a file with a large header. # This is line 2271 of a file with a large header. # This is line 2272 of a file with a large header. # This is line 2273 of a file with a large header. # This is line 2274 of a file with a large header. # This is line 2275 of a file with a large header. # This is line 2276 of a file with a large header. # This is line 2277 of a file with a large header. # This is line 2278 of a file with a large header. # This is line 2279 of a file with a large header. # This is line 2280 of a file with a large header. # This is line 2281 of a file with a large header. # This is line 2282 of a file with a large header. # This is line 2283 of a file with a large header. # This is line 2284 of a file with a large header. # This is line 2285 of a file with a large header. # This is line 2286 of a file with a large header. # This is line 2287 of a file with a large header. # This is line 2288 of a file with a large header. # This is line 2289 of a file with a large header. # This is line 2290 of a file with a large header. # This is line 2291 of a file with a large header. # This is line 2292 of a file with a large header. # This is line 2293 of a file with a large header. # This is line 2294 of a file with a large header. # This is line 2295 of a file with a large header. # This is line 2296 of a file with a large header. # This is line 2297 of a file with a large header. # This is line 2298 of a file with a large header. # This is line 2299 of a file with a large header. # This is line 2300 of a file with a large header. # This is line 2301 of a file with a large header. # This is line 2302 of a file with a large header. # This is line 2303 of a file with a large header. # This is line 2304 of a file with a large header. # This is line 2305 of a file with a large header. # This is line 2306 of a file with a large header. # This is line 2307 of a file with a large header. # This is line 2308 of a file with a large header. # This is line 2309 of a file with a large header. # This is line 2310 of a file with a large header. # This is line 2311 of a file with a large header. # This is line 2312 of a file with a large header. # This is line 2313 of a file with a large header. # This is line 2314 of a file with a large header. # This is line 2315 of a file with a large header. # This is line 2316 of a file with a large header. # This is line 2317 of a file with a large header. # This is line 2318 of a file with a large header. # This is line 2319 of a file with a large header. # This is line 2320 of a file with a large header. # This is line 2321 of a file with a large header. # This is line 2322 of a file with a large header. # This is line 2323 of a file with a large header. # This is line 2324 of a file with a large header. # This is line 2325 of a file with a large header. # This is line 2326 of a file with a large header. # This is line 2327 of a file with a large header. # This is line 2328 of a file with a large header. # This is line 2329 of a file with a large header. # This is line 2330 of a file with a large header. # This is line 2331 of a file with a large header. # This is line 2332 of a file with a large header. # This is line 2333 of a file with a large header. # This is line 2334 of a file with a large header. # This is line 2335 of a file with a large header. # This is line 2336 of a file with a large header. # This is line 2337 of a file with a large header. # This is line 2338 of a file with a large header. # This is line 2339 of a file with a large header. # This is line 2340 of a file with a large header. # This is line 2341 of a file with a large header. # This is line 2342 of a file with a large header. # This is line 2343 of a file with a large header. # This is line 2344 of a file with a large header. # This is line 2345 of a file with a large header. # This is line 2346 of a file with a large header. # This is line 2347 of a file with a large header. # This is line 2348 of a file with a large header. # This is line 2349 of a file with a large header. # This is line 2350 of a file with a large header. # This is line 2351 of a file with a large header. # This is line 2352 of a file with a large header. # This is line 2353 of a file with a large header. # This is line 2354 of a file with a large header. # This is line 2355 of a file with a large header. # This is line 2356 of a file with a large header. # This is line 2357 of a file with a large header. # This is line 2358 of a file with a large header. # This is line 2359 of a file with a large header. # This is line 2360 of a file with a large header. # This is line 2361 of a file with a large header. # This is line 2362 of a file with a large header. # This is line 2363 of a file with a large header. # This is line 2364 of a file with a large header. # This is line 2365 of a file with a large header. # This is line 2366 of a file with a large header. # This is line 2367 of a file with a large header. # This is line 2368 of a file with a large header. # This is line 2369 of a file with a large header. # This is line 2370 of a file with a large header. # This is line 2371 of a file with a large header. # This is line 2372 of a file with a large header. # This is line 2373 of a file with a large header. # This is line 2374 of a file with a large header. # This is line 2375 of a file with a large header. # This is line 2376 of a file with a large header. # This is line 2377 of a file with a large header. # This is line 2378 of a file with a large header. # This is line 2379 of a file with a large header. # This is line 2380 of a file with a large header. # This is line 2381 of a file with a large header. # This is line 2382 of a file with a large header. # This is line 2383 of a file with a large header. # This is line 2384 of a file with a large header. # This is line 2385 of a file with a large header. # This is line 2386 of a file with a large header. # This is line 2387 of a file with a large header. # This is line 2388 of a file with a large header. # This is line 2389 of a file with a large header. # This is line 2390 of a file with a large header. # This is line 2391 of a file with a large header. # This is line 2392 of a file with a large header. # This is line 2393 of a file with a large header. # This is line 2394 of a file with a large header. # This is line 2395 of a file with a large header. # This is line 2396 of a file with a large header. # This is line 2397 of a file with a large header. # This is line 2398 of a file with a large header. # This is line 2399 of a file with a large header. # This is line 2400 of a file with a large header. # This is line 2401 of a file with a large header. # This is line 2402 of a file with a large header. # This is line 2403 of a file with a large header. # This is line 2404 of a file with a large header. # This is line 2405 of a file with a large header. # This is line 2406 of a file with a large header. # This is line 2407 of a file with a large header. # This is line 2408 of a file with a large header. # This is line 2409 of a file with a large header. # This is line 2410 of a file with a large header. # This is line 2411 of a file with a large header. # This is line 2412 of a file with a large header. # This is line 2413 of a file with a large header. # This is line 2414 of a file with a large header. # This is line 2415 of a file with a large header. # This is line 2416 of a file with a large header. # This is line 2417 of a file with a large header. # This is line 2418 of a file with a large header. # This is line 2419 of a file with a large header. # This is line 2420 of a file with a large header. # This is line 2421 of a file with a large header. # This is line 2422 of a file with a large header. # This is line 2423 of a file with a large header. # This is line 2424 of a file with a large header. # This is line 2425 of a file with a large header. # This is line 2426 of a file with a large header. # This is line 2427 of a file with a large header. # This is line 2428 of a file with a large header. # This is line 2429 of a file with a large header. # This is line 2430 of a file with a large header. # This is line 2431 of a file with a large header. # This is line 2432 of a file with a large header. # This is line 2433 of a file with a large header. # This is line 2434 of a file with a large header. # This is line 2435 of a file with a large header. # This is line 2436 of a file with a large header. # This is line 2437 of a file with a large header. # This is line 2438 of a file with a large header. # This is line 2439 of a file with a large header. # This is line 2440 of a file with a large header. # This is line 2441 of a file with a large header. # This is line 2442 of a file with a large header. # This is line 2443 of a file with a large header. # This is line 2444 of a file with a large header. # This is line 2445 of a file with a large header. # This is line 2446 of a file with a large header. # This is line 2447 of a file with a large header. # This is line 2448 of a file with a large header. # This is line 2449 of a file with a large header. # This is line 2450 of a file with a large header. # This is line 2451 of a file with a large header. # This is line 2452 of a file with a large header. # This is line 2453 of a file with a large header. # This is line 2454 of a file with a large header. # This is line 2455 of a file with a large header. # This is line 2456 of a file with a large header. # This is line 2457 of a file with a large header. # This is line 2458 of a file with a large header. # This is line 2459 of a file with a large header. # This is line 2460 of a file with a large header. # This is line 2461 of a file with a large header. # This is line 2462 of a file with a large header. # This is line 2463 of a file with a large header. # This is line 2464 of a file with a large header. # This is line 2465 of a file with a large header. # This is line 2466 of a file with a large header. # This is line 2467 of a file with a large header. # This is line 2468 of a file with a large header. # This is line 2469 of a file with a large header. # This is line 2470 of a file with a large header. # This is line 2471 of a file with a large header. # This is line 2472 of a file with a large header. # This is line 2473 of a file with a large header. # This is line 2474 of a file with a large header. # This is line 2475 of a file with a large header. # This is line 2476 of a file with a large header. # This is line 2477 of a file with a large header. # This is line 2478 of a file with a large header. # This is line 2479 of a file with a large header. # This is line 2480 of a file with a large header. # This is line 2481 of a file with a large header. # This is line 2482 of a file with a large header. # This is line 2483 of a file with a large header. # This is line 2484 of a file with a large header. # This is line 2485 of a file with a large header. # This is line 2486 of a file with a large header. # This is line 2487 of a file with a large header. # This is line 2488 of a file with a large header. # This is line 2489 of a file with a large header. # This is line 2490 of a file with a large header. # This is line 2491 of a file with a large header. # This is line 2492 of a file with a large header. # This is line 2493 of a file with a large header. # This is line 2494 of a file with a large header. # This is line 2495 of a file with a large header. # This is line 2496 of a file with a large header. # This is line 2497 of a file with a large header. # This is line 2498 of a file with a large header. # This is line 2499 of a file with a large header. # This is line 2500 of a file with a large header. # This is line 2501 of a file with a large header. # This is line 2502 of a file with a large header. # This is line 2503 of a file with a large header. # This is line 2504 of a file with a large header. # This is line 2505 of a file with a large header. # This is line 2506 of a file with a large header. # This is line 2507 of a file with a large header. # This is line 2508 of a file with a large header. # This is line 2509 of a file with a large header. # This is line 2510 of a file with a large header. # This is line 2511 of a file with a large header. # This is line 2512 of a file with a large header. # This is line 2513 of a file with a large header. # This is line 2514 of a file with a large header. # This is line 2515 of a file with a large header. # This is line 2516 of a file with a large header. # This is line 2517 of a file with a large header. # This is line 2518 of a file with a large header. # This is line 2519 of a file with a large header. # This is line 2520 of a file with a large header. # This is line 2521 of a file with a large header. # This is line 2522 of a file with a large header. # This is line 2523 of a file with a large header. # This is line 2524 of a file with a large header. # This is line 2525 of a file with a large header. # This is line 2526 of a file with a large header. # This is line 2527 of a file with a large header. # This is line 2528 of a file with a large header. # This is line 2529 of a file with a large header. # This is line 2530 of a file with a large header. # This is line 2531 of a file with a large header. # This is line 2532 of a file with a large header. # This is line 2533 of a file with a large header. # This is line 2534 of a file with a large header. # This is line 2535 of a file with a large header. # This is line 2536 of a file with a large header. # This is line 2537 of a file with a large header. # This is line 2538 of a file with a large header. # This is line 2539 of a file with a large header. # This is line 2540 of a file with a large header. # This is line 2541 of a file with a large header. # This is line 2542 of a file with a large header. # This is line 2543 of a file with a large header. # This is line 2544 of a file with a large header. # This is line 2545 of a file with a large header. # This is line 2546 of a file with a large header. # This is line 2547 of a file with a large header. # This is line 2548 of a file with a large header. # This is line 2549 of a file with a large header. # This is line 2550 of a file with a large header. # This is line 2551 of a file with a large header. # This is line 2552 of a file with a large header. # This is line 2553 of a file with a large header. # This is line 2554 of a file with a large header. # This is line 2555 of a file with a large header. # This is line 2556 of a file with a large header. # This is line 2557 of a file with a large header. # This is line 2558 of a file with a large header. # This is line 2559 of a file with a large header. # This is line 2560 of a file with a large header. # This is line 2561 of a file with a large header. # This is line 2562 of a file with a large header. # This is line 2563 of a file with a large header. # This is line 2564 of a file with a large header. # This is line 2565 of a file with a large header. # This is line 2566 of a file with a large header. # This is line 2567 of a file with a large header. # This is line 2568 of a file with a large header. # This is line 2569 of a file with a large header. # This is line 2570 of a file with a large header. # This is line 2571 of a file with a large header. # This is line 2572 of a file with a large header. # This is line 2573 of a file with a large header. # This is line 2574 of a file with a large header. # This is line 2575 of a file with a large header. # This is line 2576 of a file with a large header. # This is line 2577 of a file with a large header. # This is line 2578 of a file with a large header. # This is line 2579 of a file with a large header. # This is line 2580 of a file with a large header. # This is line 2581 of a file with a large header. # This is line 2582 of a file with a large header. # This is line 2583 of a file with a large header. # This is line 2584 of a file with a large header. # This is line 2585 of a file with a large header. # This is line 2586 of a file with a large header. # This is line 2587 of a file with a large header. # This is line 2588 of a file with a large header. # This is line 2589 of a file with a large header. # This is line 2590 of a file with a large header. # This is line 2591 of a file with a large header. # This is line 2592 of a file with a large header. # This is line 2593 of a file with a large header. # This is line 2594 of a file with a large header. # This is line 2595 of a file with a large header. # This is line 2596 of a file with a large header. # This is line 2597 of a file with a large header. # This is line 2598 of a file with a large header. # This is line 2599 of a file with a large header. # This is line 2600 of a file with a large header. # This is line 2601 of a file with a large header. # This is line 2602 of a file with a large header. # This is line 2603 of a file with a large header. # This is line 2604 of a file with a large header. # This is line 2605 of a file with a large header. # This is line 2606 of a file with a large header. # This is line 2607 of a file with a large header. # This is line 2608 of a file with a large header. # This is line 2609 of a file with a large header. # This is line 2610 of a file with a large header. # This is line 2611 of a file with a large header. # This is line 2612 of a file with a large header. # This is line 2613 of a file with a large header. # This is line 2614 of a file with a large header. # This is line 2615 of a file with a large header. # This is line 2616 of a file with a large header. # This is line 2617 of a file with a large header. # This is line 2618 of a file with a large header. # This is line 2619 of a file with a large header. # This is line 2620 of a file with a large header. # This is line 2621 of a file with a large header. # This is line 2622 of a file with a large header. # This is line 2623 of a file with a large header. # This is line 2624 of a file with a large header. # This is line 2625 of a file with a large header. # This is line 2626 of a file with a large header. # This is line 2627 of a file with a large header. # This is line 2628 of a file with a large header. # This is line 2629 of a file with a large header. # This is line 2630 of a file with a large header. # This is line 2631 of a file with a large header. # This is line 2632 of a file with a large header. # This is line 2633 of a file with a large header. # This is line 2634 of a file with a large header. # This is line 2635 of a file with a large header. # This is line 2636 of a file with a large header. # This is line 2637 of a file with a large header. # This is line 2638 of a file with a large header. # This is line 2639 of a file with a large header. # This is line 2640 of a file with a large header. # This is line 2641 of a file with a large header. # This is line 2642 of a file with a large header. # This is line 2643 of a file with a large header. # This is line 2644 of a file with a large header. # This is line 2645 of a file with a large header. # This is line 2646 of a file with a large header. # This is line 2647 of a file with a large header. # This is line 2648 of a file with a large header. # This is line 2649 of a file with a large header. # This is line 2650 of a file with a large header. # This is line 2651 of a file with a large header. # This is line 2652 of a file with a large header. # This is line 2653 of a file with a large header. # This is line 2654 of a file with a large header. # This is line 2655 of a file with a large header. # This is line 2656 of a file with a large header. # This is line 2657 of a file with a large header. # This is line 2658 of a file with a large header. # This is line 2659 of a file with a large header. # This is line 2660 of a file with a large header. # This is line 2661 of a file with a large header. # This is line 2662 of a file with a large header. # This is line 2663 of a file with a large header. # This is line 2664 of a file with a large header. # This is line 2665 of a file with a large header. # This is line 2666 of a file with a large header. # This is line 2667 of a file with a large header. # This is line 2668 of a file with a large header. # This is line 2669 of a file with a large header. # This is line 2670 of a file with a large header. # This is line 2671 of a file with a large header. # This is line 2672 of a file with a large header. # This is line 2673 of a file with a large header. # This is line 2674 of a file with a large header. # This is line 2675 of a file with a large header. # This is line 2676 of a file with a large header. # This is line 2677 of a file with a large header. # This is line 2678 of a file with a large header. # This is line 2679 of a file with a large header. # This is line 2680 of a file with a large header. # This is line 2681 of a file with a large header. # This is line 2682 of a file with a large header. # This is line 2683 of a file with a large header. # This is line 2684 of a file with a large header. # This is line 2685 of a file with a large header. # This is line 2686 of a file with a large header. # This is line 2687 of a file with a large header. # This is line 2688 of a file with a large header. # This is line 2689 of a file with a large header. # This is line 2690 of a file with a large header. # This is line 2691 of a file with a large header. # This is line 2692 of a file with a large header. # This is line 2693 of a file with a large header. # This is line 2694 of a file with a large header. # This is line 2695 of a file with a large header. # This is line 2696 of a file with a large header. # This is line 2697 of a file with a large header. # This is line 2698 of a file with a large header. # This is line 2699 of a file with a large header. # This is line 2700 of a file with a large header. # This is line 2701 of a file with a large header. # This is line 2702 of a file with a large header. # This is line 2703 of a file with a large header. # This is line 2704 of a file with a large header. # This is line 2705 of a file with a large header. # This is line 2706 of a file with a large header. # This is line 2707 of a file with a large header. # This is line 2708 of a file with a large header. # This is line 2709 of a file with a large header. # This is line 2710 of a file with a large header. # This is line 2711 of a file with a large header. # This is line 2712 of a file with a large header. # This is line 2713 of a file with a large header. # This is line 2714 of a file with a large header. # This is line 2715 of a file with a large header. # This is line 2716 of a file with a large header. # This is line 2717 of a file with a large header. # This is line 2718 of a file with a large header. # This is line 2719 of a file with a large header. # This is line 2720 of a file with a large header. # This is line 2721 of a file with a large header. # This is line 2722 of a file with a large header. # This is line 2723 of a file with a large header. # This is line 2724 of a file with a large header. # This is line 2725 of a file with a large header. # This is line 2726 of a file with a large header. # This is line 2727 of a file with a large header. # This is line 2728 of a file with a large header. # This is line 2729 of a file with a large header. # This is line 2730 of a file with a large header. # This is line 2731 of a file with a large header. # This is line 2732 of a file with a large header. # This is line 2733 of a file with a large header. # This is line 2734 of a file with a large header. # This is line 2735 of a file with a large header. # This is line 2736 of a file with a large header. # This is line 2737 of a file with a large header. # This is line 2738 of a file with a large header. # This is line 2739 of a file with a large header. # This is line 2740 of a file with a large header. # This is line 2741 of a file with a large header. # This is line 2742 of a file with a large header. # This is line 2743 of a file with a large header. # This is line 2744 of a file with a large header. # This is line 2745 of a file with a large header. # This is line 2746 of a file with a large header. # This is line 2747 of a file with a large header. # This is line 2748 of a file with a large header. # This is line 2749 of a file with a large header. # This is line 2750 of a file with a large header. # This is line 2751 of a file with a large header. # This is line 2752 of a file with a large header. # This is line 2753 of a file with a large header. # This is line 2754 of a file with a large header. # This is line 2755 of a file with a large header. # This is line 2756 of a file with a large header. # This is line 2757 of a file with a large header. # This is line 2758 of a file with a large header. # This is line 2759 of a file with a large header. # This is line 2760 of a file with a large header. # This is line 2761 of a file with a large header. # This is line 2762 of a file with a large header. # This is line 2763 of a file with a large header. # This is line 2764 of a file with a large header. # This is line 2765 of a file with a large header. # This is line 2766 of a file with a large header. # This is line 2767 of a file with a large header. # This is line 2768 of a file with a large header. # This is line 2769 of a file with a large header. # This is line 2770 of a file with a large header. # This is line 2771 of a file with a large header. # This is line 2772 of a file with a large header. # This is line 2773 of a file with a large header. # This is line 2774 of a file with a large header. # This is line 2775 of a file with a large header. # This is line 2776 of a file with a large header. # This is line 2777 of a file with a large header. # This is line 2778 of a file with a large header. # This is line 2779 of a file with a large header. # This is line 2780 of a file with a large header. # This is line 2781 of a file with a large header. # This is line 2782 of a file with a large header. # This is line 2783 of a file with a large header. # This is line 2784 of a file with a large header. # This is line 2785 of a file with a large header. # This is line 2786 of a file with a large header. # This is line 2787 of a file with a large header. # This is line 2788 of a file with a large header. # This is line 2789 of a file with a large header. # This is line 2790 of a file with a large header. # This is line 2791 of a file with a large header. # This is line 2792 of a file with a large header. # This is line 2793 of a file with a large header. # This is line 2794 of a file with a large header. # This is line 2795 of a file with a large header. # This is line 2796 of a file with a large header. # This is line 2797 of a file with a large header. # This is line 2798 of a file with a large header. # This is line 2799 of a file with a large header. # This is line 2800 of a file with a large header. # This is line 2801 of a file with a large header. # This is line 2802 of a file with a large header. # This is line 2803 of a file with a large header. # This is line 2804 of a file with a large header. # This is line 2805 of a file with a large header. # This is line 2806 of a file with a large header. # This is line 2807 of a file with a large header. # This is line 2808 of a file with a large header. # This is line 2809 of a file with a large header. # This is line 2810 of a file with a large header. # This is line 2811 of a file with a large header. # This is line 2812 of a file with a large header. # This is line 2813 of a file with a large header. # This is line 2814 of a file with a large header. # This is line 2815 of a file with a large header. # This is line 2816 of a file with a large header. # This is line 2817 of a file with a large header. # This is line 2818 of a file with a large header. # This is line 2819 of a file with a large header. # This is line 2820 of a file with a large header. # This is line 2821 of a file with a large header. # This is line 2822 of a file with a large header. # This is line 2823 of a file with a large header. # This is line 2824 of a file with a large header. # This is line 2825 of a file with a large header. # This is line 2826 of a file with a large header. # This is line 2827 of a file with a large header. # This is line 2828 of a file with a large header. # This is line 2829 of a file with a large header. # This is line 2830 of a file with a large header. # This is line 2831 of a file with a large header. # This is line 2832 of a file with a large header. # This is line 2833 of a file with a large header. # This is line 2834 of a file with a large header. # This is line 2835 of a file with a large header. # This is line 2836 of a file with a large header. # This is line 2837 of a file with a large header. # This is line 2838 of a file with a large header. # This is line 2839 of a file with a large header. # This is line 2840 of a file with a large header. # This is line 2841 of a file with a large header. # This is line 2842 of a file with a large header. # This is line 2843 of a file with a large header. # This is line 2844 of a file with a large header. # This is line 2845 of a file with a large header. # This is line 2846 of a file with a large header. # This is line 2847 of a file with a large header. # This is line 2848 of a file with a large header. # This is line 2849 of a file with a large header. # This is line 2850 of a file with a large header. # This is line 2851 of a file with a large header. # This is line 2852 of a file with a large header. # This is line 2853 of a file with a large header. # This is line 2854 of a file with a large header. # This is line 2855 of a file with a large header. # This is line 2856 of a file with a large header. # This is line 2857 of a file with a large header. # This is line 2858 of a file with a large header. # This is line 2859 of a file with a large header. # This is line 2860 of a file with a large header. # This is line 2861 of a file with a large header. # This is line 2862 of a file with a large header. # This is line 2863 of a file with a large header. # This is line 2864 of a file with a large header. # This is line 2865 of a file with a large header. # This is line 2866 of a file with a large header. # This is line 2867 of a file with a large header. # This is line 2868 of a file with a large header. # This is line 2869 of a file with a large header. # This is line 2870 of a file with a large header. # This is line 2871 of a file with a large header. # This is line 2872 of a file with a large header. # This is line 2873 of a file with a large header. # This is line 2874 of a file with a large header. # This is line 2875 of a file with a large header. # This is line 2876 of a file with a large header. # This is line 2877 of a file with a large header. # This is line 2878 of a file with a large header. # This is line 2879 of a file with a large header. # This is line 2880 of a file with a large header. # This is line 2881 of a file with a large header. # This is line 2882 of a file with a large header. # This is line 2883 of a file with a large header. # This is line 2884 of a file with a large header. # This is line 2885 of a file with a large header. # This is line 2886 of a file with a large header. # This is line 2887 of a file with a large header. # This is line 2888 of a file with a large header. # This is line 2889 of a file with a large header. # This is line 2890 of a file with a large header. # This is line 2891 of a file with a large header. # This is line 2892 of a file with a large header. # This is line 2893 of a file with a large header. # This is line 2894 of a file with a large header. # This is line 2895 of a file with a large header. # This is line 2896 of a file with a large header. # This is line 2897 of a file with a large header. # This is line 2898 of a file with a large header. # This is line 2899 of a file with a large header. # This is line 2900 of a file with a large header. # This is line 2901 of a file with a large header. # This is line 2902 of a file with a large header. # This is line 2903 of a file with a large header. # This is line 2904 of a file with a large header. # This is line 2905 of a file with a large header. # This is line 2906 of a file with a large header. # This is line 2907 of a file with a large header. # This is line 2908 of a file with a large header. # This is line 2909 of a file with a large header. # This is line 2910 of a file with a large header. # This is line 2911 of a file with a large header. # This is line 2912 of a file with a large header. # This is line 2913 of a file with a large header. # This is line 2914 of a file with a large header. # This is line 2915 of a file with a large header. # This is line 2916 of a file with a large header. # This is line 2917 of a file with a large header. # This is line 2918 of a file with a large header. # This is line 2919 of a file with a large header. # This is line 2920 of a file with a large header. # This is line 2921 of a file with a large header. # This is line 2922 of a file with a large header. # This is line 2923 of a file with a large header. # This is line 2924 of a file with a large header. # This is line 2925 of a file with a large header. # This is line 2926 of a file with a large header. # This is line 2927 of a file with a large header. # This is line 2928 of a file with a large header. # This is line 2929 of a file with a large header. # This is line 2930 of a file with a large header. # This is line 2931 of a file with a large header. # This is line 2932 of a file with a large header. # This is line 2933 of a file with a large header. # This is line 2934 of a file with a large header. # This is line 2935 of a file with a large header. # This is line 2936 of a file with a large header. # This is line 2937 of a file with a large header. # This is line 2938 of a file with a large header. # This is line 2939 of a file with a large header. # This is line 2940 of a file with a large header. # This is line 2941 of a file with a large header. # This is line 2942 of a file with a large header. # This is line 2943 of a file with a large header. # This is line 2944 of a file with a large header. # This is line 2945 of a file with a large header. # This is line 2946 of a file with a large header. # This is line 2947 of a file with a large header. # This is line 2948 of a file with a large header. # This is line 2949 of a file with a large header. # This is line 2950 of a file with a large header. # This is line 2951 of a file with a large header. # This is line 2952 of a file with a large header. # This is line 2953 of a file with a large header. # This is line 2954 of a file with a large header. # This is line 2955 of a file with a large header. # This is line 2956 of a file with a large header. # This is line 2957 of a file with a large header. # This is line 2958 of a file with a large header. # This is line 2959 of a file with a large header. # This is line 2960 of a file with a large header. # This is line 2961 of a file with a large header. # This is line 2962 of a file with a large header. # This is line 2963 of a file with a large header. # This is line 2964 of a file with a large header. # This is line 2965 of a file with a large header. # This is line 2966 of a file with a large header. # This is line 2967 of a file with a large header. # This is line 2968 of a file with a large header. # This is line 2969 of a file with a large header. # This is line 2970 of a file with a large header. # This is line 2971 of a file with a large header. # This is line 2972 of a file with a large header. # This is line 2973 of a file with a large header. # This is line 2974 of a file with a large header. # This is line 2975 of a file with a large header. # This is line 2976 of a file with a large header. # This is line 2977 of a file with a large header. # This is line 2978 of a file with a large header. # This is line 2979 of a file with a large header. # This is line 2980 of a file with a large header. # This is line 2981 of a file with a large header. # This is line 2982 of a file with a large header. # This is line 2983 of a file with a large header. # This is line 2984 of a file with a large header. # This is line 2985 of a file with a large header. # This is line 2986 of a file with a large header. # This is line 2987 of a file with a large header. # This is line 2988 of a file with a large header. # This is line 2989 of a file with a large header. # This is line 2990 of a file with a large header. # This is line 2991 of a file with a large header. # This is line 2992 of a file with a large header. # This is line 2993 of a file with a large header. # This is line 2994 of a file with a large header. # This is line 2995 of a file with a large header. # This is line 2996 of a file with a large header. # This is line 2997 of a file with a large header. # This is line 2998 of a file with a large header. # This is line 2999 of a file with a large header. # This is line 3000 of a file with a large header. # This is line 3001 of a file with a large header. # This is line 3002 of a file with a large header. # This is line 3003 of a file with a large header. # This is line 3004 of a file with a large header. # This is line 3005 of a file with a large header. # This is line 3006 of a file with a large header. # This is line 3007 of a file with a large header. # This is line 3008 of a file with a large header. # This is line 3009 of a file with a large header. # This is line 3010 of a file with a large header. # This is line 3011 of a file with a large header. # This is line 3012 of a file with a large header. # This is line 3013 of a file with a large header. # This is line 3014 of a file with a large header. # This is line 3015 of a file with a large header. # This is line 3016 of a file with a large header. # This is line 3017 of a file with a large header. # This is line 3018 of a file with a large header. # This is line 3019 of a file with a large header. # This is line 3020 of a file with a large header. # This is line 3021 of a file with a large header. # This is line 3022 of a file with a large header. # This is line 3023 of a file with a large header. # This is line 3024 of a file with a large header. # This is line 3025 of a file with a large header. # This is line 3026 of a file with a large header. # This is line 3027 of a file with a large header. # This is line 3028 of a file with a large header. # This is line 3029 of a file with a large header. # This is line 3030 of a file with a large header. # This is line 3031 of a file with a large header. # This is line 3032 of a file with a large header. # This is line 3033 of a file with a large header. # This is line 3034 of a file with a large header. # This is line 3035 of a file with a large header. # This is line 3036 of a file with a large header. # This is line 3037 of a file with a large header. # This is line 3038 of a file with a large header. # This is line 3039 of a file with a large header. # This is line 3040 of a file with a large header. # This is line 3041 of a file with a large header. # This is line 3042 of a file with a large header. # This is line 3043 of a file with a large header. # This is line 3044 of a file with a large header. # This is line 3045 of a file with a large header. # This is line 3046 of a file with a large header. # This is line 3047 of a file with a large header. # This is line 3048 of a file with a large header. # This is line 3049 of a file with a large header. # This is line 3050 of a file with a large header. # This is line 3051 of a file with a large header. # This is line 3052 of a file with a large header. # This is line 3053 of a file with a large header. # This is line 3054 of a file with a large header. # This is line 3055 of a file with a large header. # This is line 3056 of a file with a large header. # This is line 3057 of a file with a large header. # This is line 3058 of a file with a large header. # This is line 3059 of a file with a large header. # This is line 3060 of a file with a large header. # This is line 3061 of a file with a large header. # This is line 3062 of a file with a large header. # This is line 3063 of a file with a large header. # This is line 3064 of a file with a large header. # This is line 3065 of a file with a large header. # This is line 3066 of a file with a large header. # This is line 3067 of a file with a large header. # This is line 3068 of a file with a large header. # This is line 3069 of a file with a large header. # This is line 3070 of a file with a large header. # This is line 3071 of a file with a large header. # This is line 3072 of a file with a large header. # This is line 3073 of a file with a large header. # This is line 3074 of a file with a large header. # This is line 3075 of a file with a large header. # This is line 3076 of a file with a large header. # This is line 3077 of a file with a large header. # This is line 3078 of a file with a large header. # This is line 3079 of a file with a large header. # This is line 3080 of a file with a large header. # This is line 3081 of a file with a large header. # This is line 3082 of a file with a large header. # This is line 3083 of a file with a large header. # This is line 3084 of a file with a large header. # This is line 3085 of a file with a large header. # This is line 3086 of a file with a large header. # This is line 3087 of a file with a large header. # This is line 3088 of a file with a large header. # This is line 3089 of a file with a large header. # This is line 3090 of a file with a large header. # This is line 3091 of a file with a large header. # This is line 3092 of a file with a large header. # This is line 3093 of a file with a large header. # This is line 3094 of a file with a large header. # This is line 3095 of a file with a large header. # This is line 3096 of a file with a large header. # This is line 3097 of a file with a large header. # This is line 3098 of a file with a large header. # This is line 3099 of a file with a large header. # This is line 3100 of a file with a large header. # This is line 3101 of a file with a large header. # This is line 3102 of a file with a large header. # This is line 3103 of a file with a large header. # This is line 3104 of a file with a large header. # This is line 3105 of a file with a large header. # This is line 3106 of a file with a large header. # This is line 3107 of a file with a large header. # This is line 3108 of a file with a large header. # This is line 3109 of a file with a large header. # This is line 3110 of a file with a large header. # This is line 3111 of a file with a large header. # This is line 3112 of a file with a large header. # This is line 3113 of a file with a large header. # This is line 3114 of a file with a large header. # This is line 3115 of a file with a large header. # This is line 3116 of a file with a large header. # This is line 3117 of a file with a large header. # This is line 3118 of a file with a large header. # This is line 3119 of a file with a large header. # This is line 3120 of a file with a large header. # This is line 3121 of a file with a large header. # This is line 3122 of a file with a large header. # This is line 3123 of a file with a large header. # This is line 3124 of a file with a large header. # This is line 3125 of a file with a large header. # This is line 3126 of a file with a large header. # This is line 3127 of a file with a large header. # This is line 3128 of a file with a large header. # This is line 3129 of a file with a large header. # This is line 3130 of a file with a large header. # This is line 3131 of a file with a large header. # This is line 3132 of a file with a large header. # This is line 3133 of a file with a large header. # This is line 3134 of a file with a large header. # This is line 3135 of a file with a large header. # This is line 3136 of a file with a large header. # This is line 3137 of a file with a large header. # This is line 3138 of a file with a large header. # This is line 3139 of a file with a large header. # This is line 3140 of a file with a large header. # This is line 3141 of a file with a large header. # This is line 3142 of a file with a large header. # This is line 3143 of a file with a large header. # This is line 3144 of a file with a large header. # This is line 3145 of a file with a large header. # This is line 3146 of a file with a large header. # This is line 3147 of a file with a large header. # This is line 3148 of a file with a large header. # This is line 3149 of a file with a large header. # This is line 3150 of a file with a large header. # This is line 3151 of a file with a large header. # This is line 3152 of a file with a large header. # This is line 3153 of a file with a large header. # This is line 3154 of a file with a large header. # This is line 3155 of a file with a large header. # This is line 3156 of a file with a large header. # This is line 3157 of a file with a large header. # This is line 3158 of a file with a large header. # This is line 3159 of a file with a large header. # This is line 3160 of a file with a large header. # This is line 3161 of a file with a large header. # This is line 3162 of a file with a large header. # This is line 3163 of a file with a large header. # This is line 3164 of a file with a large header. # This is line 3165 of a file with a large header. # This is line 3166 of a file with a large header. # This is line 3167 of a file with a large header. # This is line 3168 of a file with a large header. # This is line 3169 of a file with a large header. # This is line 3170 of a file with a large header. # This is line 3171 of a file with a large header. # This is line 3172 of a file with a large header. # This is line 3173 of a file with a large header. # This is line 3174 of a file with a large header. # This is line 3175 of a file with a large header. # This is line 3176 of a file with a large header. # This is line 3177 of a file with a large header. # This is line 3178 of a file with a large header. # This is line 3179 of a file with a large header. # This is line 3180 of a file with a large header. # This is line 3181 of a file with a large header. # This is line 3182 of a file with a large header. # This is line 3183 of a file with a large header. # This is line 3184 of a file with a large header. # This is line 3185 of a file with a large header. # This is line 3186 of a file with a large header. # This is line 3187 of a file with a large header. # This is line 3188 of a file with a large header. # This is line 3189 of a file with a large header. # This is line 3190 of a file with a large header. # This is line 3191 of a file with a large header. # This is line 3192 of a file with a large header. # This is line 3193 of a file with a large header. # This is line 3194 of a file with a large header. # This is line 3195 of a file with a large header. # This is line 3196 of a file with a large header. # This is line 3197 of a file with a large header. # This is line 3198 of a file with a large header. # This is line 3199 of a file with a large header. # This is line 3200 of a file with a large header. # This is line 3201 of a file with a large header. # This is line 3202 of a file with a large header. # This is line 3203 of a file with a large header. # This is line 3204 of a file with a large header. # This is line 3205 of a file with a large header. # This is line 3206 of a file with a large header. # This is line 3207 of a file with a large header. # This is line 3208 of a file with a large header. # This is line 3209 of a file with a large header. # This is line 3210 of a file with a large header. # This is line 3211 of a file with a large header. # This is line 3212 of a file with a large header. # This is line 3213 of a file with a large header. # This is line 3214 of a file with a large header. # This is line 3215 of a file with a large header. # This is line 3216 of a file with a large header. # This is line 3217 of a file with a large header. # This is line 3218 of a file with a large header. # This is line 3219 of a file with a large header. # This is line 3220 of a file with a large header. # This is line 3221 of a file with a large header. # This is line 3222 of a file with a large header. # This is line 3223 of a file with a large header. # This is line 3224 of a file with a large header. # This is line 3225 of a file with a large header. # This is line 3226 of a file with a large header. # This is line 3227 of a file with a large header. # This is line 3228 of a file with a large header. # This is line 3229 of a file with a large header. # This is line 3230 of a file with a large header. # This is line 3231 of a file with a large header. # This is line 3232 of a file with a large header. # This is line 3233 of a file with a large header. # This is line 3234 of a file with a large header. # This is line 3235 of a file with a large header. # This is line 3236 of a file with a large header. # This is line 3237 of a file with a large header. # This is line 3238 of a file with a large header. # This is line 3239 of a file with a large header. # This is line 3240 of a file with a large header. # This is line 3241 of a file with a large header. # This is line 3242 of a file with a large header. # This is line 3243 of a file with a large header. # This is line 3244 of a file with a large header. # This is line 3245 of a file with a large header. # This is line 3246 of a file with a large header. # This is line 3247 of a file with a large header. # This is line 3248 of a file with a large header. # This is line 3249 of a file with a large header. # This is line 3250 of a file with a large header. # This is line 3251 of a file with a large header. # This is line 3252 of a file with a large header. # This is line 3253 of a file with a large header. # This is line 3254 of a file with a large header. # This is line 3255 of a file with a large header. # This is line 3256 of a file with a large header. # This is line 3257 of a file with a large header. # This is line 3258 of a file with a large header. # This is line 3259 of a file with a large header. # This is line 3260 of a file with a large header. # This is line 3261 of a file with a large header. # This is line 3262 of a file with a large header. # This is line 3263 of a file with a large header. # This is line 3264 of a file with a large header. # This is line 3265 of a file with a large header. # This is line 3266 of a file with a large header. # This is line 3267 of a file with a large header. # This is line 3268 of a file with a large header. # This is line 3269 of a file with a large header. # This is line 3270 of a file with a large header. # This is line 3271 of a file with a large header. # This is line 3272 of a file with a large header. # This is line 3273 of a file with a large header. # This is line 3274 of a file with a large header. # This is line 3275 of a file with a large header. # This is line 3276 of a file with a large header. # This is line 3277 of a file with a large header. # This is line 3278 of a file with a large header. # This is line 3279 of a file with a large header. # This is line 3280 of a file with a large header. # This is line 3281 of a file with a large header. # This is line 3282 of a file with a large header. # This is line 3283 of a file with a large header. # This is line 3284 of a file with a large header. # This is line 3285 of a file with a large header. # This is line 3286 of a file with a large header. # This is line 3287 of a file with a large header. # This is line 3288 of a file with a large header. # This is line 3289 of a file with a large header. # This is line 3290 of a file with a large header. # This is line 3291 of a file with a large header. # This is line 3292 of a file with a large header. # This is line 3293 of a file with a large header. # This is line 3294 of a file with a large header. # This is line 3295 of a file with a large header. # This is line 3296 of a file with a large header. # This is line 3297 of a file with a large header. # This is line 3298 of a file with a large header. # This is line 3299 of a file with a large header. # This is line 3300 of a file with a large header. # This is line 3301 of a file with a large header. # This is line 3302 of a file with a large header. # This is line 3303 of a file with a large header. # This is line 3304 of a file with a large header. # This is line 3305 of a file with a large header. # This is line 3306 of a file with a large header. # This is line 3307 of a file with a large header. # This is line 3308 of a file with a large header. # This is line 3309 of a file with a large header. # This is line 3310 of a file with a large header. # This is line 3311 of a file with a large header. # This is line 3312 of a file with a large header. # This is line 3313 of a file with a large header. # This is line 3314 of a file with a large header. # This is line 3315 of a file with a large header. # This is line 3316 of a file with a large header. # This is line 3317 of a file with a large header. # This is line 3318 of a file with a large header. # This is line 3319 of a file with a large header. # This is line 3320 of a file with a large header. # This is line 3321 of a file with a large header. # This is line 3322 of a file with a large header. # This is line 3323 of a file with a large header. # This is line 3324 of a file with a large header. # This is line 3325 of a file with a large header. # This is line 3326 of a file with a large header. # This is line 3327 of a file with a large header. # This is line 3328 of a file with a large header. # This is line 3329 of a file with a large header. # This is line 3330 of a file with a large header. # This is line 3331 of a file with a large header. # This is line 3332 of a file with a large header. # This is line 3333 of a file with a large header. # This is line 3334 of a file with a large header. # This is line 3335 of a file with a large header. # This is line 3336 of a file with a large header. # This is line 3337 of a file with a large header. # This is line 3338 of a file with a large header. # This is line 3339 of a file with a large header. # This is line 3340 of a file with a large header. # This is line 3341 of a file with a large header. # This is line 3342 of a file with a large header. # This is line 3343 of a file with a large header. # This is line 3344 of a file with a large header. # This is line 3345 of a file with a large header. # This is line 3346 of a file with a large header. # This is line 3347 of a file with a large header. # This is line 3348 of a file with a large header. # This is line 3349 of a file with a large header. # This is line 3350 of a file with a large header. # This is line 3351 of a file with a large header. # This is line 3352 of a file with a large header. # This is line 3353 of a file with a large header. # This is line 3354 of a file with a large header. # This is line 3355 of a file with a large header. # This is line 3356 of a file with a large header. # This is line 3357 of a file with a large header. # This is line 3358 of a file with a large header. # This is line 3359 of a file with a large header. # This is line 3360 of a file with a large header. # This is line 3361 of a file with a large header. # This is line 3362 of a file with a large header. # This is line 3363 of a file with a large header. # This is line 3364 of a file with a large header. # This is line 3365 of a file with a large header. # This is line 3366 of a file with a large header. # This is line 3367 of a file with a large header. # This is line 3368 of a file with a large header. # This is line 3369 of a file with a large header. # This is line 3370 of a file with a large header. # This is line 3371 of a file with a large header. # This is line 3372 of a file with a large header. # This is line 3373 of a file with a large header. # This is line 3374 of a file with a large header. # This is line 3375 of a file with a large header. # This is line 3376 of a file with a large header. # This is line 3377 of a file with a large header. # This is line 3378 of a file with a large header. # This is line 3379 of a file with a large header. # This is line 3380 of a file with a large header. # This is line 3381 of a file with a large header. # This is line 3382 of a file with a large header. # This is line 3383 of a file with a large header. # This is line 3384 of a file with a large header. # This is line 3385 of a file with a large header. # This is line 3386 of a file with a large header. # This is line 3387 of a file with a large header. # This is line 3388 of a file with a large header. # This is line 3389 of a file with a large header. # This is line 3390 of a file with a large header. # This is line 3391 of a file with a large header. # This is line 3392 of a file with a large header. # This is line 3393 of a file with a large header. # This is line 3394 of a file with a large header. # This is line 3395 of a file with a large header. # This is line 3396 of a file with a large header. # This is line 3397 of a file with a large header. # This is line 3398 of a file with a large header. # This is line 3399 of a file with a large header. # This is line 3400 of a file with a large header. # This is line 3401 of a file with a large header. # This is line 3402 of a file with a large header. # This is line 3403 of a file with a large header. # This is line 3404 of a file with a large header. # This is line 3405 of a file with a large header. # This is line 3406 of a file with a large header. # This is line 3407 of a file with a large header. # This is line 3408 of a file with a large header. # This is line 3409 of a file with a large header. # This is line 3410 of a file with a large header. # This is line 3411 of a file with a large header. # This is line 3412 of a file with a large header. # This is line 3413 of a file with a large header. # This is line 3414 of a file with a large header. # This is line 3415 of a file with a large header. # This is line 3416 of a file with a large header. # This is line 3417 of a file with a large header. # This is line 3418 of a file with a large header. # This is line 3419 of a file with a large header. # This is line 3420 of a file with a large header. # This is line 3421 of a file with a large header. # This is line 3422 of a file with a large header. # This is line 3423 of a file with a large header. # This is line 3424 of a file with a large header. # This is line 3425 of a file with a large header. # This is line 3426 of a file with a large header. # This is line 3427 of a file with a large header. # This is line 3428 of a file with a large header. # This is line 3429 of a file with a large header. # This is line 3430 of a file with a large header. # This is line 3431 of a file with a large header. # This is line 3432 of a file with a large header. # This is line 3433 of a file with a large header. # This is line 3434 of a file with a large header. # This is line 3435 of a file with a large header. # This is line 3436 of a file with a large header. # This is line 3437 of a file with a large header. # This is line 3438 of a file with a large header. # This is line 3439 of a file with a large header. # This is line 3440 of a file with a large header. # This is line 3441 of a file with a large header. # This is line 3442 of a file with a large header. # This is line 3443 of a file with a large header. # This is line 3444 of a file with a large header. # This is line 3445 of a file with a large header. # This is line 3446 of a file with a large header. # This is line 3447 of a file with a large header. # This is line 3448 of a file with a large header. # This is line 3449 of a file with a large header. # This is line 3450 of a file with a large header. # This is line 3451 of a file with a large header. # This is line 3452 of a file with a large header. # This is line 3453 of a file with a large header. # This is line 3454 of a file with a large header. # This is line 3455 of a file with a large header. # This is line 3456 of a file with a large header. # This is line 3457 of a file with a large header. # This is line 3458 of a file with a large header. # This is line 3459 of a file with a large header. # This is line 3460 of a file with a large header. # This is line 3461 of a file with a large header. # This is line 3462 of a file with a large header. # This is line 3463 of a file with a large header. # This is line 3464 of a file with a large header. # This is line 3465 of a file with a large header. # This is line 3466 of a file with a large header. # This is line 3467 of a file with a large header. # This is line 3468 of a file with a large header. # This is line 3469 of a file with a large header. # This is line 3470 of a file with a large header. # This is line 3471 of a file with a large header. # This is line 3472 of a file with a large header. # This is line 3473 of a file with a large header. # This is line 3474 of a file with a large header. # This is line 3475 of a file with a large header. # This is line 3476 of a file with a large header. # This is line 3477 of a file with a large header. # This is line 3478 of a file with a large header. # This is line 3479 of a file with a large header. # This is line 3480 of a file with a large header. # This is line 3481 of a file with a large header. # This is line 3482 of a file with a large header. # This is line 3483 of a file with a large header. # This is line 3484 of a file with a large header. # This is line 3485 of a file with a large header. # This is line 3486 of a file with a large header. # This is line 3487 of a file with a large header. # This is line 3488 of a file with a large header. # This is line 3489 of a file with a large header. # This is line 3490 of a file with a large header. # This is line 3491 of a file with a large header. # This is line 3492 of a file with a large header. # This is line 3493 of a file with a large header. # This is line 3494 of a file with a large header. # This is line 3495 of a file with a large header. # This is line 3496 of a file with a large header. # This is line 3497 of a file with a large header. # This is line 3498 of a file with a large header. # This is line 3499 of a file with a large header. # This is line 3500 of a file with a large header. # This is line 3501 of a file with a large header. # This is line 3502 of a file with a large header. # This is line 3503 of a file with a large header. # This is line 3504 of a file with a large header. # This is line 3505 of a file with a large header. # This is line 3506 of a file with a large header. # This is line 3507 of a file with a large header. # This is line 3508 of a file with a large header. # This is line 3509 of a file with a large header. # This is line 3510 of a file with a large header. # This is line 3511 of a file with a large header. # This is line 3512 of a file with a large header. # This is line 3513 of a file with a large header. # This is line 3514 of a file with a large header. # This is line 3515 of a file with a large header. # This is line 3516 of a file with a large header. # This is line 3517 of a file with a large header. # This is line 3518 of a file with a large header. # This is line 3519 of a file with a large header. # This is line 3520 of a file with a large header. # This is line 3521 of a file with a large header. # This is line 3522 of a file with a large header. # This is line 3523 of a file with a large header. # This is line 3524 of a file with a large header. # This is line 3525 of a file with a large header. # This is line 3526 of a file with a large header. # This is line 3527 of a file with a large header. # This is line 3528 of a file with a large header. # This is line 3529 of a file with a large header. # This is line 3530 of a file with a large header. # This is line 3531 of a file with a large header. # This is line 3532 of a file with a large header. # This is line 3533 of a file with a large header. # This is line 3534 of a file with a large header. # This is line 3535 of a file with a large header. # This is line 3536 of a file with a large header. # This is line 3537 of a file with a large header. # This is line 3538 of a file with a large header. # This is line 3539 of a file with a large header. # This is line 3540 of a file with a large header. # This is line 3541 of a file with a large header. # This is line 3542 of a file with a large header. # This is line 3543 of a file with a large header. # This is line 3544 of a file with a large header. # This is line 3545 of a file with a large header. # This is line 3546 of a file with a large header. # This is line 3547 of a file with a large header. # This is line 3548 of a file with a large header. # This is line 3549 of a file with a large header. # This is line 3550 of a file with a large header. # This is line 3551 of a file with a large header. # This is line 3552 of a file with a large header. # This is line 3553 of a file with a large header. # This is line 3554 of a file with a large header. # This is line 3555 of a file with a large header. # This is line 3556 of a file with a large header. # This is line 3557 of a file with a large header. # This is line 3558 of a file with a large header. # This is line 3559 of a file with a large header. # This is line 3560 of a file with a large header. # This is line 3561 of a file with a large header. # This is line 3562 of a file with a large header. # This is line 3563 of a file with a large header. # This is line 3564 of a file with a large header. # This is line 3565 of a file with a large header. # This is line 3566 of a file with a large header. # This is line 3567 of a file with a large header. # This is line 3568 of a file with a large header. # This is line 3569 of a file with a large header. # This is line 3570 of a file with a large header. # This is line 3571 of a file with a large header. # This is line 3572 of a file with a large header. # This is line 3573 of a file with a large header. # This is line 3574 of a file with a large header. # This is line 3575 of a file with a large header. # This is line 3576 of a file with a large header. # This is line 3577 of a file with a large header. # This is line 3578 of a file with a large header. # This is line 3579 of a file with a large header. # This is line 3580 of a file with a large header. # This is line 3581 of a file with a large header. # This is line 3582 of a file with a large header. # This is line 3583 of a file with a large header. # This is line 3584 of a file with a large header. # This is line 3585 of a file with a large header. # This is line 3586 of a file with a large header. # This is line 3587 of a file with a large header. # This is line 3588 of a file with a large header. # This is line 3589 of a file with a large header. # This is line 3590 of a file with a large header. # This is line 3591 of a file with a large header. # This is line 3592 of a file with a large header. # This is line 3593 of a file with a large header. # This is line 3594 of a file with a large header. # This is line 3595 of a file with a large header. # This is line 3596 of a file with a large header. # This is line 3597 of a file with a large header. # This is line 3598 of a file with a large header. # This is line 3599 of a file with a large header. # This is line 3600 of a file with a large header. # This is line 3601 of a file with a large header. # This is line 3602 of a file with a large header. # This is line 3603 of a file with a large header. # This is line 3604 of a file with a large header. # This is line 3605 of a file with a large header. # This is line 3606 of a file with a large header. # This is line 3607 of a file with a large header. # This is line 3608 of a file with a large header. # This is line 3609 of a file with a large header. # This is line 3610 of a file with a large header. # This is line 3611 of a file with a large header. # This is line 3612 of a file with a large header. # This is line 3613 of a file with a large header. # This is line 3614 of a file with a large header. # This is line 3615 of a file with a large header. # This is line 3616 of a file with a large header. # This is line 3617 of a file with a large header. # This is line 3618 of a file with a large header. # This is line 3619 of a file with a large header. # This is line 3620 of a file with a large header. # This is line 3621 of a file with a large header. # This is line 3622 of a file with a large header. # This is line 3623 of a file with a large header. # This is line 3624 of a file with a large header. # This is line 3625 of a file with a large header. # This is line 3626 of a file with a large header. # This is line 3627 of a file with a large header. # This is line 3628 of a file with a large header. # This is line 3629 of a file with a large header. # This is line 3630 of a file with a large header. # This is line 3631 of a file with a large header. # This is line 3632 of a file with a large header. # This is line 3633 of a file with a large header. # This is line 3634 of a file with a large header. # This is line 3635 of a file with a large header. # This is line 3636 of a file with a large header. # This is line 3637 of a file with a large header. # This is line 3638 of a file with a large header. # This is line 3639 of a file with a large header. # This is line 3640 of a file with a large header. # This is line 3641 of a file with a large header. # This is line 3642 of a file with a large header. # This is line 3643 of a file with a large header. # This is line 3644 of a file with a large header. # This is line 3645 of a file with a large header. # This is line 3646 of a file with a large header. # This is line 3647 of a file with a large header. # This is line 3648 of a file with a large header. # This is line 3649 of a file with a large header. # This is line 3650 of a file with a large header. # This is line 3651 of a file with a large header. # This is line 3652 of a file with a large header. # This is line 3653 of a file with a large header. # This is line 3654 of a file with a large header. # This is line 3655 of a file with a large header. # This is line 3656 of a file with a large header. # This is line 3657 of a file with a large header. # This is line 3658 of a file with a large header. # This is line 3659 of a file with a large header. # This is line 3660 of a file with a large header. # This is line 3661 of a file with a large header. # This is line 3662 of a file with a large header. # This is line 3663 of a file with a large header. # This is line 3664 of a file with a large header. # This is line 3665 of a file with a large header. # This is line 3666 of a file with a large header. # This is line 3667 of a file with a large header. # This is line 3668 of a file with a large header. # This is line 3669 of a file with a large header. # This is line 3670 of a file with a large header. # This is line 3671 of a file with a large header. # This is line 3672 of a file with a large header. # This is line 3673 of a file with a large header. # This is line 3674 of a file with a large header. # This is line 3675 of a file with a large header. # This is line 3676 of a file with a large header. # This is line 3677 of a file with a large header. # This is line 3678 of a file with a large header. # This is line 3679 of a file with a large header. # This is line 3680 of a file with a large header. # This is line 3681 of a file with a large header. # This is line 3682 of a file with a large header. # This is line 3683 of a file with a large header. # This is line 3684 of a file with a large header. # This is line 3685 of a file with a large header. # This is line 3686 of a file with a large header. # This is line 3687 of a file with a large header. # This is line 3688 of a file with a large header. # This is line 3689 of a file with a large header. # This is line 3690 of a file with a large header. # This is line 3691 of a file with a large header. # This is line 3692 of a file with a large header. # This is line 3693 of a file with a large header. # This is line 3694 of a file with a large header. # This is line 3695 of a file with a large header. # This is line 3696 of a file with a large header. # This is line 3697 of a file with a large header. # This is line 3698 of a file with a large header. # This is line 3699 of a file with a large header. # This is line 3700 of a file with a large header. # This is line 3701 of a file with a large header. # This is line 3702 of a file with a large header. # This is line 3703 of a file with a large header. # This is line 3704 of a file with a large header. # This is line 3705 of a file with a large header. # This is line 3706 of a file with a large header. # This is line 3707 of a file with a large header. # This is line 3708 of a file with a large header. # This is line 3709 of a file with a large header. # This is line 3710 of a file with a large header. # This is line 3711 of a file with a large header. # This is line 3712 of a file with a large header. # This is line 3713 of a file with a large header. # This is line 3714 of a file with a large header. # This is line 3715 of a file with a large header. # This is line 3716 of a file with a large header. # This is line 3717 of a file with a large header. # This is line 3718 of a file with a large header. # This is line 3719 of a file with a large header. # This is line 3720 of a file with a large header. # This is line 3721 of a file with a large header. # This is line 3722 of a file with a large header. # This is line 3723 of a file with a large header. # This is line 3724 of a file with a large header. # This is line 3725 of a file with a large header. # This is line 3726 of a file with a large header. # This is line 3727 of a file with a large header. # This is line 3728 of a file with a large header. # This is line 3729 of a file with a large header. # This is line 3730 of a file with a large header. # This is line 3731 of a file with a large header. # This is line 3732 of a file with a large header. # This is line 3733 of a file with a large header. # This is line 3734 of a file with a large header. # This is line 3735 of a file with a large header. # This is line 3736 of a file with a large header. # This is line 3737 of a file with a large header. # This is line 3738 of a file with a large header. # This is line 3739 of a file with a large header. # This is line 3740 of a file with a large header. # This is line 3741 of a file with a large header. # This is line 3742 of a file with a large header. # This is line 3743 of a file with a large header. # This is line 3744 of a file with a large header. # This is line 3745 of a file with a large header. # This is line 3746 of a file with a large header. # This is line 3747 of a file with a large header. # This is line 3748 of a file with a large header. # This is line 3749 of a file with a large header. # This is line 3750 of a file with a large header. # This is line 3751 of a file with a large header. # This is line 3752 of a file with a large header. # This is line 3753 of a file with a large header. # This is line 3754 of a file with a large header. # This is line 3755 of a file with a large header. # This is line 3756 of a file with a large header. # This is line 3757 of a file with a large header. # This is line 3758 of a file with a large header. # This is line 3759 of a file with a large header. # This is line 3760 of a file with a large header. # This is line 3761 of a file with a large header. # This is line 3762 of a file with a large header. # This is line 3763 of a file with a large header. # This is line 3764 of a file with a large header. # This is line 3765 of a file with a large header. # This is line 3766 of a file with a large header. # This is line 3767 of a file with a large header. # This is line 3768 of a file with a large header. # This is line 3769 of a file with a large header. # This is line 3770 of a file with a large header. # This is line 3771 of a file with a large header. # This is line 3772 of a file with a large header. # This is line 3773 of a file with a large header. # This is line 3774 of a file with a large header. # This is line 3775 of a file with a large header. # This is line 3776 of a file with a large header. # This is line 3777 of a file with a large header. # This is line 3778 of a file with a large header. # This is line 3779 of a file with a large header. # This is line 3780 of a file with a large header. # This is line 3781 of a file with a large header. # This is line 3782 of a file with a large header. # This is line 3783 of a file with a large header. # This is line 3784 of a file with a large header. # This is line 3785 of a file with a large header. # This is line 3786 of a file with a large header. # This is line 3787 of a file with a large header. # This is line 3788 of a file with a large header. # This is line 3789 of a file with a large header. # This is line 3790 of a file with a large header. # This is line 3791 of a file with a large header. # This is line 3792 of a file with a large header. # This is line 3793 of a file with a large header. # This is line 3794 of a file with a large header. # This is line 3795 of a file with a large header. # This is line 3796 of a file with a large header. # This is line 3797 of a file with a large header. # This is line 3798 of a file with a large header. # This is line 3799 of a file with a large header. # This is line 3800 of a file with a large header. # This is line 3801 of a file with a large header. # This is line 3802 of a file with a large header. # This is line 3803 of a file with a large header. # This is line 3804 of a file with a large header. # This is line 3805 of a file with a large header. # This is line 3806 of a file with a large header. # This is line 3807 of a file with a large header. # This is line 3808 of a file with a large header. # This is line 3809 of a file with a large header. # This is line 3810 of a file with a large header. # This is line 3811 of a file with a large header. # This is line 3812 of a file with a large header. # This is line 3813 of a file with a large header. # This is line 3814 of a file with a large header. # This is line 3815 of a file with a large header. # This is line 3816 of a file with a large header. # This is line 3817 of a file with a large header. # This is line 3818 of a file with a large header. # This is line 3819 of a file with a large header. # This is line 3820 of a file with a large header. # This is line 3821 of a file with a large header. # This is line 3822 of a file with a large header. # This is line 3823 of a file with a large header. # This is line 3824 of a file with a large header. # This is line 3825 of a file with a large header. # This is line 3826 of a file with a large header. # This is line 3827 of a file with a large header. # This is line 3828 of a file with a large header. # This is line 3829 of a file with a large header. # This is line 3830 of a file with a large header. # This is line 3831 of a file with a large header. # This is line 3832 of a file with a large header. # This is line 3833 of a file with a large header. # This is line 3834 of a file with a large header. # This is line 3835 of a file with a large header. # This is line 3836 of a file with a large header. # This is line 3837 of a file with a large header. # This is line 3838 of a file with a large header. # This is line 3839 of a file with a large header. # This is line 3840 of a file with a large header. # This is line 3841 of a file with a large header. # This is line 3842 of a file with a large header. # This is line 3843 of a file with a large header. # This is line 3844 of a file with a large header. # This is line 3845 of a file with a large header. # This is line 3846 of a file with a large header. # This is line 3847 of a file with a large header. # This is line 3848 of a file with a large header. # This is line 3849 of a file with a large header. # This is line 3850 of a file with a large header. # This is line 3851 of a file with a large header. # This is line 3852 of a file with a large header. # This is line 3853 of a file with a large header. # This is line 3854 of a file with a large header. # This is line 3855 of a file with a large header. # This is line 3856 of a file with a large header. # This is line 3857 of a file with a large header. # This is line 3858 of a file with a large header. # This is line 3859 of a file with a large header. # This is line 3860 of a file with a large header. # This is line 3861 of a file with a large header. # This is line 3862 of a file with a large header. # This is line 3863 of a file with a large header. # This is line 3864 of a file with a large header. # This is line 3865 of a file with a large header. # This is line 3866 of a file with a large header. # This is line 3867 of a file with a large header. # This is line 3868 of a file with a large header. # This is line 3869 of a file with a large header. # This is line 3870 of a file with a large header. # This is line 3871 of a file with a large header. # This is line 3872 of a file with a large header. # This is line 3873 of a file with a large header. # This is line 3874 of a file with a large header. # This is line 3875 of a file with a large header. # This is line 3876 of a file with a large header. # This is line 3877 of a file with a large header. # This is line 3878 of a file with a large header. # This is line 3879 of a file with a large header. # This is line 3880 of a file with a large header. # This is line 3881 of a file with a large header. # This is line 3882 of a file with a large header. # This is line 3883 of a file with a large header. # This is line 3884 of a file with a large header. # This is line 3885 of a file with a large header. # This is line 3886 of a file with a large header. # This is line 3887 of a file with a large header. # This is line 3888 of a file with a large header. # This is line 3889 of a file with a large header. # This is line 3890 of a file with a large header. # This is line 3891 of a file with a large header. # This is line 3892 of a file with a large header. # This is line 3893 of a file with a large header. # This is line 3894 of a file with a large header. # This is line 3895 of a file with a large header. # This is line 3896 of a file with a large header. # This is line 3897 of a file with a large header. # This is line 3898 of a file with a large header. # This is line 3899 of a file with a large header. # This is line 3900 of a file with a large header. # This is line 3901 of a file with a large header. # This is line 3902 of a file with a large header. # This is line 3903 of a file with a large header. # This is line 3904 of a file with a large header. # This is line 3905 of a file with a large header. # This is line 3906 of a file with a large header. # This is line 3907 of a file with a large header. # This is line 3908 of a file with a large header. # This is line 3909 of a file with a large header. # This is line 3910 of a file with a large header. # This is line 3911 of a file with a large header. # This is line 3912 of a file with a large header. # This is line 3913 of a file with a large header. # This is line 3914 of a file with a large header. # This is line 3915 of a file with a large header. # This is line 3916 of a file with a large header. # This is line 3917 of a file with a large header. # This is line 3918 of a file with a large header. # This is line 3919 of a file with a large header. # This is line 3920 of a file with a large header. # This is line 3921 of a file with a large header. # This is line 3922 of a file with a large header. # This is line 3923 of a file with a large header. # This is line 3924 of a file with a large header. # This is line 3925 of a file with a large header. # This is line 3926 of a file with a large header. # This is line 3927 of a file with a large header. # This is line 3928 of a file with a large header. # This is line 3929 of a file with a large header. # This is line 3930 of a file with a large header. # This is line 3931 of a file with a large header. # This is line 3932 of a file with a large header. # This is line 3933 of a file with a large header. # This is line 3934 of a file with a large header. # This is line 3935 of a file with a large header. # This is line 3936 of a file with a large header. # This is line 3937 of a file with a large header. # This is line 3938 of a file with a large header. # This is line 3939 of a file with a large header. # This is line 3940 of a file with a large header. # This is line 3941 of a file with a large header. # This is line 3942 of a file with a large header. # This is line 3943 of a file with a large header. # This is line 3944 of a file with a large header. # This is line 3945 of a file with a large header. # This is line 3946 of a file with a large header. # This is line 3947 of a file with a large header. # This is line 3948 of a file with a large header. # This is line 3949 of a file with a large header. # This is line 3950 of a file with a large header. # This is line 3951 of a file with a large header. # This is line 3952 of a file with a large header. # This is line 3953 of a file with a large header. # This is line 3954 of a file with a large header. # This is line 3955 of a file with a large header. # This is line 3956 of a file with a large header. # This is line 3957 of a file with a large header. # This is line 3958 of a file with a large header. # This is line 3959 of a file with a large header. # This is line 3960 of a file with a large header. # This is line 3961 of a file with a large header. # This is line 3962 of a file with a large header. # This is line 3963 of a file with a large header. # This is line 3964 of a file with a large header. # This is line 3965 of a file with a large header. # This is line 3966 of a file with a large header. # This is line 3967 of a file with a large header. # This is line 3968 of a file with a large header. # This is line 3969 of a file with a large header. # This is line 3970 of a file with a large header. # This is line 3971 of a file with a large header. # This is line 3972 of a file with a large header. # This is line 3973 of a file with a large header. # This is line 3974 of a file with a large header. # This is line 3975 of a file with a large header. # This is line 3976 of a file with a large header. # This is line 3977 of a file with a large header. # This is line 3978 of a file with a large header. # This is line 3979 of a file with a large header. # This is line 3980 of a file with a large header. # This is line 3981 of a file with a large header. # This is line 3982 of a file with a large header. # This is line 3983 of a file with a large header. # This is line 3984 of a file with a large header. # This is line 3985 of a file with a large header. # This is line 3986 of a file with a large header. # This is line 3987 of a file with a large header. # This is line 3988 of a file with a large header. # This is line 3989 of a file with a large header. # This is line 3990 of a file with a large header. # This is line 3991 of a file with a large header. # This is line 3992 of a file with a large header. # This is line 3993 of a file with a large header. # This is line 3994 of a file with a large header. # This is line 3995 of a file with a large header. # This is line 3996 of a file with a large header. # This is line 3997 of a file with a large header. # This is line 3998 of a file with a large header. # This is line 3999 of a file with a large header. chr1 10 20 a1 1 + chr1 100 200 a2 2 - chr1 98650 98750 a1 100 + chr1 1 100 A 0 + 1 100 0 2 10,10 0,90 BCY]lW>I"V/(ܿ+ٵkj64!2ޝqv֎SR%T*"*MjJEy#x" ̝;3LwpΙ{{oN܃YTYJkmns\3lg{*gVg1&Fvvֶ]Dk @8'm`64Tb[E@aS'-$B" ئS;RTG%aDĞh! cZT'Iba lIllt=He %} PΨ 䏁Al  ¨th"qZ#YaYj'"`,T$< ,G6\8bCĠԡ#Wɰe0s༬86&~0 qеG}&%Z R^pƋ!: vgmgUl.6l^ zbn 51\;aG-Έ־f'2>2^y*kᠳBa/oB' 8DsL*#l'Nmx!S'V։,+'v 7 -Ju`8RZK2^G1^'BK袆hub!!^9TGz^6"zm=revdOCyɒ_4Q•#ǦVgHah( ['=%fw[Hzl6//&D )^^erŒ)>~wsx+#Z.  N=cHHJ-7r)c[N7,ή_w]Qxcwt Ʀ3,ZKjZj?ݚWꙵs#7%0pfT;^,a5}íg_lU]o<&^F 9)uFx0PuEAbú 4l+nqA-FphYS\( {ڨ [nsum;rn;ֶ]>lݶW__biu"Y&KAecQ`+^l_O'nI > ׻J`p_>=I`AoዕX`'bÝ_85G?HhU :$ 9…ɊfpdΨpI8M2y|e)ժy*uz%ժ))\<}ӏD^˸PsJf;">ER a$ܨ&9ĘDΨ3wI\Cޘl*}#wƳ(*1&ܘ } dckLIdޚSSϹ)pOj͍;ykR$n~x _̫1jO>V{ &_6 _/P5w^ͫ2}XFp]p KL/)y-{*6l؂O6|jl^y@5_=W&5V ^~@m¯Pto-Ps~9Y"xj S5/)Z' &L?]`jv|s6E"BCo6ǵ XELI)~nڧI&Ca 涞%K[GgƐa;/' ٟ7ǽv&5mՏ9̾2~Ͳ~67.Wf4Ջr<1 {{1sneR̗%NXSSUUFVT@>Bq8ku/woӻۗi[߬Vog?ܾ&<[cR6pS<2;TʴDaGyzQ$P@t*uctDLqT9xT^4zb3zNCbLY|R+JBGa1rp!ũB\B=yMN@[IRGiUSc)!! &;z|2grF$X%D F];>& &B Ǻz.OAnXn.rJcQօ!wm*kɽڝx*R?i B8)QdQ#` 9>9?:;;), %=aj pRyA\C>qQO;rR"ӋZY([(dar.kgc~1<K`BCBCX[h\El*m ""H![HZ4UI mI6llPTTkP+x'JVEEZ9$gd2?{=n l]DtcޑZgOSã{p݄i‘ =:3185ZǺ>2٘zS)Lq쎐XݫqAgp֘ aDPb#QűS@aB4g1EiwpVQ,fN=3 /{䍘0hțѲ0߬T*1'" 6D0T-Y&!::ɤT%DTkCCH&cI/o2B1R jxw֔Ұ(sCH3caFjsGPS)q IYpSP,Fʂd ¬9f"|OAR(% M$ ,#L%$ŹGh/O !tPSP8| JAja-!aHA\`Y4YBh ch ]|-d:16śڴ8\f;$bTAfwskcs;W̞bD^\Mh>'ƐOq0{3Z|O夅8u#׍YBa/7X(6 _RL™c~{,D". vJǔExrselhOWFj'Y҅eK/*ha݆ õ0ʭ\k:| \~kQKk1x}wг%%/YZ|jX=! 58-.Rݠ᡹t zvZ|so$pree{12D {?VwrɞᶖS\(z*Z'S!fX^?J# e+FZR 1Wrî+\gWWKn־~3nxD;Ǎ^Upu͖Vxf&XI] 7g6ήOެf> cn^˕~0u)ف;b\ww&To%'Xõgr\&lPphiQgZ% d}pܪd8Z)o&3C=f91 hc031+xacp\lO>ҪL`3KB3/=fWT9o0ם_o"a϶Y{"njL3O=f>ogxcm^Λ˞o3 ? =k(sc,,a1߷5~;9an]o%n^-?f~[no/@2lTBCchr1 9 9 m3 chr1 50 150 m1 chr1 10 20  {Ra_withLargeHeader_gzipped.bed͊/YVqU(go*hZ78p$OA?9?~|_~ǿˏ?_׿?^x o~^X M|G+|GKYҡCK-Z:thҩҩSKN-Z:WK_-}h-}WK_-}OK?-_ƴOK?-tiҥKK.[K.-]Ztkҭ[KnKKn-=ZzhңGKkZK^-ZzjҫWK^l'?O~d>~' O&p7w0s1s2s3s4s5s6c7; g0xvXa?; h06ÈvX3aG; i%0ØvXsaO; jE06èvXaW; ke0øvXa_; l06vX3ag; m0vXsao; n06vXaw; o0vXa; p06wX3a v` v` v` v` v` v` v` v` v` v?p7{&6ocF6v` v` v` v` v` v` v` v` v` v` v` v` v` v` v` v` v` v` v` v` v` v` v` v` v` v` v` v` v` v` v` v` v` v` v` vdKvdKvdKvdKvdKvdKvdKvdKvdKvdKvdKvdKvdKvdKvdK)gJC+JR-eKvdKvdKvdKvdKvdKvdKvdKvdKvdKvdKvdKvdKvdKvdKvdKvdKvdKvdKvdKvdKvdKvdKvdKvdKvdKvdKvdKvdKvdKvdp]vw.;ep]vw.;ep]vw.;ep]vw.;ep]vw.;wK-o?7nozWeop]vw.;ep]vw.;ep]vw.;ep]vw.;ep]vw.;ep]vw.;ep=v;c{p=v;c{p=v;c{p=v;c{p=v;c{p=v;c{p=v. ~'// p=v;c{p=v;c{p=v;c{p=v;c{p=v;c{pWpWpWpWpWpWpWpWpWpWpWpWpWpWpWpWpWpWpWpWpWpWpWpWpWpWpWpWpWpW~'Q~NC~WpWpWpWpWpWpWpWpWpWpWpWpWpWpWppppppppppppppppppppppppppppppppppppppppppppppppppp7p7p7p7p7p7p7p7p7p7p7p7p7p7p7p7p7p7p7p7p7p7p7p7p7p7p7p7p7p7p7p7p7p7p7p7p7p7p7p7p7p7p7p7p7p7p7p7p7p7pppppppppppppppppppppppppppppppppppppppppppppppppppw~2}M47D-M47D$M>7r3}4M>7s3}DM>#7t3}TM>c7u3}dM>7v3}tM>7w3}τM>#7x3}ϔM>c7y3}ϤM>7z3}ϴM>7{3}M>#7|3}Mq;n}ǭw[q;n}ǭw[q;n}ǭw[q;n}ǭw[q;n}ǭw[q;n}ǭw[q;n}ǭw[q;n}ǭw[q;n}ǭw[q;n}ǭw[q;n}ǭw[q;n}ǭw[q;n}ǭ[_[_[_[_[_[_[_[_[_[_[_[_[_[_[_[_[_[_[_[_[_[_[_[_[_[_[_[_[_[_[_[_[_[_[_[_[_[_[_[_[_[_[_[_[_[_[_[_[_[_[_[_[_[_[_[_[_[_[_[_[_[_[_[_[_[_[_[_[_[_[_[_[_[_[_[_[_[_[_[_[_[_[_[_[_[_[_[_[_[_[_[_[_[_[_[_[_[_[_[_]w[un}׭]w[un}׭]w[un}׭]w[un}׭]w[un}׭]w[un}׭]w[un}׭]w[un}׭]w[un}׭]w[un}׭]w[un}׭]w[un}׭]w[s{n}ϭ=[s{n}ϭ=[s{n}ϭ=[s{n}ϭ=[s{n}ϭ=[s{n}ϭ=[s{n}ϭ=[s{n}ϭ=[s{n}ϭ=[s{n}ϭ=[s{n}ϭ=[s{n}ϭ=[s{n}ϭ[_[_[_[_[_[_[_[_[_[_[_[_[_[_[_[_[_[_[_[_[_[_[_[_[_[_[_[_[_[_[_[_[_[_[_[_[_[_[_[_[_[_[_[_[_[_[_[_[_[_[_[_[_[_[_[_[_[_[_[_[_[_[_[_[_[_[_[_[_[_[_[_[_[_[_[_[_[_[_[_[_[_[_[_[_[_[_[_[_[_[_[_[_[_[_[_[_[_[_[_[߸[߸[߸[߸[߸[߸[߸[߸[߸[߸[߸[߸[߸[߸[߸[߸[߸[߸[߸[߸[߸[߸[߸[߸[߸[߸[߸[߸[߸[߸[߸[߸[߸[߸[߸[߸[߸[߸[߸[߸[߸[߸[߸[߸[߸[߸[߸[߸[߸[߸[ߺ[ߺ[ߺ[ߺ[ߺ[ߺ[ߺ[ߺ[ߺ[ߺ[ߺ[ߺ[ߺ[ߺ[ߺ[ߺ[ߺ[ߺ[ߺ[ߺ[ߺ[ߺ[ߺ[ߺ[ߺ[ߺ[ߺ[ߺ[ߺ[ߺ[ߺ[ߺ[ߺ[ߺ[ߺ[ߺ[ߺ[ߺ[ߺ[ߺ[ߺ[ߺ[ߺ[ߺ[ߺ[ߺ[ߺ[ߺ[ߺ[߲Oo&Zho&Zhog&^x}og&^x}og&^x}og&^x}og&^x}og&^x}og&^x}og&^x}og&^x}og&^x}og&^x}o 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CACATGCTAGCGCGTCGGGGTGGAGGCGTGGCGCAGGCGCAGAGAGGCGCGCCGCGCCGG CGCAGGCGCAGAGACACATGCTACCGCGTCCAGGGGTGGAGGCGTGGCGCAGGCGCAGAG AGGCGCACCGCGCCGGCGCAGGCGCAGAGACACATGCTAGCGCGTCCAGGGGTGGAGGCG TGGCGCAGGCGCAGAGACGCAAGCCTACGGGCGGGGGTTGGGGGGGCGTGTGTTGCAGGA GCAAAGTCGCACGGCGCCGGGCTGGGGCGGGGGGAGGGTGGCGCCGTGCACGCGCAGAAA CTCACGTCACGGTGGCGCGGCGCAGAGACGGGTAGAACCTCAGTAATCCGAAAAGCCGGG ATCGACCGCCCCTTGCTTGCAGCCGGGCACTACAGGACCCGCTTGCTCACGGTGCTGTGC CAGGGCGCCCCCTGCTGGCGACTAGGGCAACTGCAGGGCTCTCTTGCTTAGAGTGGTGGC CAGCGCCCCCTGCTGGCGCCGGGGCACTGCAGGGCCCTCTTGCTTACTGTATAGTGGTGG CACGCCGCCTGCTGGCAGCTAGGGACATTGCAGGGTCCTCTTGCTCAAGGTGTAGTGGCA GCACGCCCACCTGCTGGCAGCTGGGGACACTGCCGGGCCCTCTTGCTCCAACAGTACTGG CGGATTATAGGGAAACACCCGGAGCATATGCTGTTTGGTCTCAGTAGACTCCTAAATATG GGATTCCTGGGTTTAAAAGTAAAAAATAAATATGTTTAATTTGTGAACTGATTACCATCA GAATTGTACTGTTCTGTATCCCACCAGCAATGTCTAGGAATGCCTGTTTCTCCACAAAGT GTTTACTTTTGGATTTTTGCCAGTCTAACAGGTGAAGCCCTGGAGATTCTTATTAGTGAT TTGGGCTGGGGCCTGGCCATGTGTATTTTTTTAAATTTCCACTGATGATTTTGCTGCATG GCCGGTGTTGAGAATGACTGCGCAAATTTGCCGGATTTCCTTTGCTGTTCCTGCATGTAG TTTAAACGAGATTGCCAGCACCGGGTATCATTCACCATTTTTCTTTTCGTTAACTTGCCG TCAGCCTTTTCTTTGACCTCTTCTTTCTGTTCATGTGTATTTGCTGTCTCTTAGCCCAGA CTTCCCGTGTCCTTTCCACCGGGCCTTTGAGAGGTCACAGGGTCTTGATGCTGTGGTCTT CATCTGCAGGTGTCTGACTTCCAGCAACTGCTGGCCTGTGCCAGGGTGCAAGCTGAGCAC TGGAGTGGAGTTTTCCTGTGGAGAGGAGCCATGCCTAGAGTGGGATGGGCCATTGTTCAT CTTCTGGCCCCTGTTGTCTGCATGTAACTTAATACCACAACCAGGCATAGGGGAAAGATT GGAGGAAAGATGAGTGAGAGCATCAACTTCTCTCACAACCTAGGCCAGTAAGTAGTGCTT GTGCTCATCTCCTTGGCTGTGATACGTGGCCGGCCCTCGCTCCAGCAGCTGGACCCCTAC CTGCCGTCTGCTGCCATCGGAGCCCAAAGCCGGGCTGTGACTGCTCAGACCAGCCGGCTG GAGGGAGGGGCTCAGCAGGTCTGGCTTTGGCCCTGGGAGAGCAGGTGGAAGATCAGGCAG GCCATCGCTGCCACAGAACCCAGTGGATTGGCCTAGGTGGGATCTCTGAGCTCAACAAGC CCTCTCTGGGTGGTAGGTGCAGAGACGGGAGGGGCAGAGCCGCAGGCACAGCCAAGAGGG CTGAAGAAATGGTAGAACGGAGCAGCTGGTGATGTGTGGGCCCACCGGCCCCAGGCTCCT GTCTCCCCCCAGGTGTGTGGTGATGCCAGGCATGCCCTTCCCCAGCATCAGGTCTCCAGA GCTGCAGAAGACGACGGCCGACTTGGATCACACTCTTGTGAGTGTCCCCAGTGTTGCAGA GGTGAGAGGAGAGTAGACAGTGAGTGGGAGTGGCGTCGCCCCTAGGGCTCTACGGGGCCG GCGTCTCCTGTCTCCTGGAGAGGCTTCGATGCCCCTCCACACCCTCTTGATCTTCCCTGT GATGTCATCTGGAGCCCTGCTGCTTGCGGTGGCCTATAAAGCCTCCTAGTCTGGCTCCAA GGCCTGGCAGAGTCTTTCCCAGGGAAAGCTACAAGCAGCAAACAGTCTGCATGGGTCATC CCCTTCACTCCCAGCTCAGAGCCCAGGCCAGGGGCCCCCAAGAAAGGCTCTGGTGGAGAA CCTGTGCATGAAGGCTGTCAACCAGTCCATAGGCAAGCCTGGCTGCCTCCAGCTGGGTCG ACAGACAGGGGCTGGAGAAGGGGAGAAGAGGAAAGTGAGGTTGCCTGCCCTGTCTCCTAC CTGAGGCTGAGGAAGGAGAAGGGGATGCACTGTTGGGGAGGCAGCTGTAACTCAAAGCCT TAGCCTCTGTTCCCACGAAGGCAGGGCCATCAGGCACCAAAGGGATTCTGCCAGCATAGT GCTCCTGGACCAGTGATACACCCGGCACCCTGTCCTGGACACGCTGTTGGCCTGGATCTG AGCCCTGGTGGAGGTCAAAGCCACCTTTGGTTCTGCCATTGCTGCTGTGTGGAAGTTCAC TCCTGCCTTTTCCTTTCCCTAGAGCCTCCACCACCCCGAGATCACATTTCTCACTGCCTT TTGTCTGCCCAGTTTCACCAGAAGTAGGCCTCTTCCTGACAGGCAGCTGCACCACTGCCT GGCGCTGTGCCCTTCCTTTGCTCTGCCCGCTGGAGACGGTGTTTGTCATGGGCCTGGTCT GCAGGGATCCTGCTACAAAGGTGAAACCCAGGAGAGTGTGGAGTCCAGAGTGTTGCCAGG ACCCAGGCACAGGCATTAGTGCCCGTTGGAGAAAACAGGGGAATCCCGAAGAAATGGTGG GTCCTGGCCATCCGTGAGATCTTCCCAGGGCAGCTCCCCTCTGTGGAATCCAATCTGTCT TCCATCCTGCGTGGCCGAGGGCCAGGCTTCTCACTGGGCCTCTGCAGGAGGCTGCCATTT GTCCTGCCCACCTTCTTAGAAGCGAGACGGAGCAGACCCATCTGCTACTGCCCTTTCTAT AATAACTAAAGTTAGCTGCCCTGGACTATTCACCCCCTAGTCTCAATTTAAGAAGATCCC CATGGCCACAGGGCCCCTGCCTGGGGGCTTGTCACCTCCCCCACCTTCTTCCTGAGTCAT TCCTGCAGCCTTGCTCCCTAACCTGCCCCACAGCCTTGCCTGGATTTCTATCTCCCTGGC TTGGTGCCAGTTCCTCCAAGTCGATGGCACCTCCCTCCCTCTCAACCACTTGAGCAAACT CCAAGACATCTTCTACCCCAACACCAGCAATTGTGCCAAGGGCCATTAGGCTCTCAGCAT GACTATTTTTAGAGACCCCGTGTCTGTCACTGAAACCTTTTTTGTGGGAGACTATTCCTC CCATCTGCAACAGCTGCCCCTGCTGACTGCCCTTCTCTCCTCCCTCTCATCCCAGAGAAA CAGGTCAGCTGGGAGCTTCTGCCCCCACTGCCTAGGGACCAACAGGGGCAGGAGGCAGTC ACTGACCCCGAGACGTTTGCATCCTGCACAGCTAGAGATCCTTTATTAAAAGCACACTGT TGGTTTCTGCTCAGTTCTTTATTGATTGGTGTGCCGTTTTCTCTGGAAGCCTCTTAAGAA CACAGTGGCGCAGGCTGGGTGGAGCCGTCCCCCCATGGAGCACAGGCAGACAGAAGTCCC CGCCCCAGCTGTGTGGCCTCAAGCCAGCCTTCCGCTCCTTGAAGCTGGTCTCCACACAGT GCTGGTTCCGTCACCCCCTCCCAAGGAAGTAGGTCTGAGCAGCTTGTCCTGGCTGTGTCC ATGTCAGAGCAACGGCCCAAGTCTGGGTCTGGGGGGGAAGGTGTCATGGAGCCCCCTACG ATTCCCAGTCGTCCTCGTCCTCCTCTGCCTGTGGCTGCTGCGGTGGCGGCAGAGGAGGGA TGGAGTCTGACACGCGGGCAAAGGCTCCTCCGGGCCCCTCACCAGCCCCAGGTCCTTTCC CAGAGATGCCTGGAGGGAAAAGGCTGAGTGAGGGTGGTTGGTGGGAAACCCTGGTTCCCC CAGCCCCCGGAGACTTAAATACAGGAAGAAAAAGGCAGGACAGAATTACAAGGTGCTGGC CCAGGGCGGGCAGCGGCCCTGCCTCCTACCCTTGCGCCTCATGACCAGCTTGTTGAAGAG ATCCGACATCAAGTGCCCACCTTGGCTCGTGGCTCTCACTGCAACGGGAAAGCCACAGAC TGGGGTGAAGAGTTCAGTCACATGCGACCGGTGACTCCCTGTCCCCACCCCCATGACACT CCCCAGCCCTCCAAGGCCACTGTGTTTCCCAGTTAGCTCAGAGCCTCAGTCGATCCCTGA CCCAGCACCGGGCACTGATGAGACAGCGGCTGTTTGAGGAGCCACCTCCCAGCCACCTCG GGGCCAGGGCCAGGGTGTGCAGCACCACTGTACAATGGGGAAACTGGCCCAGAGAGGTGA GGCAGCTTGCCTGGGGTCACAGAGCAAGGCAAAAGCAGCGCTGGGTACAAGCTCAAAACC ATAGTGCCCAGGGCACTGCCGCTGCAGGCGCAGGCATCGCATCACACCAGTGTCTGCGTT CACAGCAGGCATCATCAGTAGCCTCCAGAGGCCTCAGGTCCAGTCTCTAAAAATATCTCA GGAGGCTGCAGTGGCTGACCATTGCCTTGGACCGCTCTTGGCAGTCGAAGAAGATTCTCC TGTCAGTTTGAGCTGGGTGAGCTTAGAGAGGAAAGCTCCACTATGGCTCCCAAACCAGGA AGGAGCCATAGCCCAGGCAGGAGGGCTGAGGACCTCTGGTGGCGGCCCAGGGCTTCCAGC ATGTGCCCTAGGGGAAGCAGGGGCCAGCTGGCAAGAGCAGGGGGTGGGCAGAAAGCACCC GGTGGACTCAGGGCTGGAGGGGAGGAGGCGATCTTGCCCAAGGCCCTCCGACTGCAAGCT CCAGGGCCCGCTCACCTTGCTCCTGCTCCTTCTGCTGCTGCTTCTCCAGCTTTCGCTCCT TCATGCTGCGCAGCTTGGCCTTGCCGATGCCCCCAGCTTGGCGGATGGACTCTAGCAGAG TGGCCAGCCACCGGAGGGGTCAACCACTTCCCTGGGAGCTCCCTGGACTGGAGCCGGGAG GTGGGGAACAGGGCAAGGAGGAAAGGCTGCTCAGGCAGGGCTGGGGAAGCTTACTGTGTC CAAGAGCCTGCTGGGAGGGAAGTCACCTCCCCTCAAACGAGGAGCCCTGCGCTGGGGAGG CCGGACCTTTGGAGACTGTGTGTGGGGGCCTGGGCACTGACTTCTGCAACCACCTGAGCG CGGGCATCCTGTGTGCAGATACTCCCTGCTTCCTCTCTAGCCCCCACCCTGCAGAGCTGG ACCCCTGAGCTAGCCATGCTCTGACAGTCTCAGTTGCACACACGAGCCAGCAGAGGGGTT TTGTGCCACTTCTGGATGCTAGGGTTACACTGGGAGACACAGCAGTGAAGCTGAAATGAA AAATGTGTTGCTGTAGTTTGTTATTAGACCCCTTCTTTCCATTGGTTTAATTAGGAATGG GGAACCCAGAGCCTCACTTGTTCAGGCTCCCTCTGCCCTAGAAGTGAGAAGTCCAGAGCT CTACAGTTTGAAAACCACTATTTTATGAACCAAGTAGAACAAGATATTTGAAATGGAAAC TATTCAAAAAATTGAGAATTTCTGACCACTTAACAAACCCACAGAAAATCCACCCGAGTG CACTGAGCACGCCAGAAATCAGGTGGCCTCAAAGAGCTGCTCCCACCTGAAGGAGACGCG CTGCTGCTGCTGTCGTCCTGCCTGGCGCCTTGGCCTACAGGGGCCGCGGTTGAGGGTGGG AGTGGGGGTGCACTGGCCAGCACCTCAGGAGCTGGGGGTGGTGGTGGGGGCGGTGGGGGT GGTGTTAGTACCCCATCTTGTAGGTCTGAAACACAAAGTGTGGGGTGTCTAGGGAAGAAG GTGTGTGACCAGGGAGGTCCCCGGCCCAGCTCCCATCCCAGAACCCAGCTCACCTACCTT GAGAGGCTCGGCTACCTCAGTGTGGAAGGTGGGCAGTTCTGGAATGGTGCCAGGGGCAGA GGGGGCAATGCCGGGGCCCAGGTCGGCAATGTACATGAGGTCGTTGGCAATGCCGGGCAG GTCAGGCAGGTAGGATGGAACATCAATCTCAGGCACCTGGCCCAGGTCTGGCACATAGAA GTAGTTCTCTGGGACCTGCAAGATTAGGCAGGGACATGTGAGAGGTGACAGGGACCTGCA GGGGCAGCCAACAAGACCTTGTGTGCACCTCCCATGGGTGGAATAAGGGGCCCAACAGCC TTGACTGGAGAGGAGCTCTGGCAAGGCCCTGGGCCACTGCACCTGTCTCCACCTCTGTCC CACCCCTCCCACCTGCTGTTCCAGCTGCTCTCTCTTGCTGATGGACAAGGGGGCATCAAA CAGCTTCTCCTCTGTCTCTGCCCCCAGCATCACATGGGTCTTTGTTACAGCACCAGCCAG GGGGTCCAGGAAGACATACTTCTTCTACCTACAGAGGCGACATGGGGGTCAGGCAAGCTG ACACCCGCTGTCCTGAGCCCATGTTCCTCTCCCACATCATCAGGGGCACAGCGTGCACTG TGGGGTCCCAGGCCTCCCGAGCCGAGCCACCCGTCACCCCCTGGCTCCTGGCCTATGTGC TGTACCTGTGTCTGATGCCCTGGGTCCCCACTAAGCCAGGCCGGGCCTCCCGCCCACACC CCTCGGCCCTGCCCTCTGGCCATACAGGTTCTCGGTGGTGTTGAAGAGCAGCAAGGAGCT GACAGAGCTGATGTTGCTGGGAAGACCCCCAAGTCCCTCTTCTGCATCGTCCTCGGGCTC CGGCTTGGTGCTCACGCACACAGGAAAGTCCTTCAGCTTCTCCTGAGAGGGCCAGGATGG CCAAGGGATGGTGAATATTTGGTGCTGGGCCTAATCAGCTGCCATCCCATCCCAGTCAGC CTCCTCTGGGGGACAGAACCCTATGGTGGCCCCGGCTCCTCCCCAGTATCCAGTCCTCCT GGTGTGTGACAGGCTATATGCGCGGCCAGCAGACCTGCAGGGCCCGCTCGTCCAGGGGGC GGTGCTTGCTCTGGATCCTGTGGCGGGGGCGTCTCTGCAGGCCAGGGTCCTGGGCGCCCG TGAAGATGGAGCCATATTCCTGCAGGCGCCCTGGAGCAGGGTACTTGGCACTGGAGAACA CCTGTGGACACAGGGACAAGTCTGAGGGGGCCCCAAGAGGCTCAGAGGGCTAGGATTGCT TGGCAGGAGAGGGTGGAGTTGGAAGCCTGGGCGAGAAGAAAGCTCAAGGTACAGGTGGGC AGCAGGGCAGAGACTGGGCAGCCTCAGAGGCACGGGGAAATGGAGGGACTGCCCAGTAGC CTCAGGACACAGGGGTATGGGGACTACCTTGATGGCCTTCTTGCTGCCCTTGATCTTCTC AATCTTGGCCTGGGCCAAGGAGACCTTCTCTCCAATGGCCTGCACCTGGCTCCGGCTCTG CTCTACCTGCTGGGAGATCCTGCCATGGAGAAGATCACAGAGGCTGGGCTGCTCCCCACC CTCTGCACACCTCCTGCTTCTAACAGCAGAGCTGCCAGGCCAGGCCCTCAGGCAAGGGCT CTGAAGTCAGGGTCACCTACTTGCCAGGGCCGATCTTGGTGCCATCCAGGGGGCCTCTAC AAGGATAATCTGACCTGCAGGGTCGAGGAGTTGACGGTGCTGAGTTCCCTGCACTCTCAG TAGGGACAGGCCCTATGCTGCCACCTGTACATGCTATCTGAAGGACAGCCTCCAGGGCAC ACAGAGGATGGTATTTACACATGCACACATGGCTACTGATGGGGCAAGCACTTCACAACC CCTCATGATCACGTGCAGCAGACAATGTGGCCTCTGCAGAGGGGGAACGGAGACCGGAGG CTGAGACTGGCAAGGCTGGACCTGAGTGTCGTCACCTAAATTCAGACGGGGAACTGCCCC TGCACATACTGAACGGCTCACTGAGCAAACCCCGAGTCCCGACCACCGCCTCAGTGTGGT CTAGCTCCTCACCTGCTTCCATCCTCCCTGGTGCGGGGTGGGCCCAGTGATATCAGCTGC CTGCTGTTCCCCAGATGTGCCAAGTGCATTCTTGTGTGCTTGCATCTCATGGAACGCCAT TTCCCCAGACATCCCTGTGGCTGGCTCCTGATGCCCGAGGCCCAAGTGTCTGATGCTTTA AGGCACATCACCCCACTCATGCTTTTCCATGTTCTTTGGCCGCAGCAAGGCCGCTCTCAC TGCAAAGTTAACTCTGATGCGTGTGTAACACAACATCCTCCTCCCAGTCGCCCCTGTAGC TCCCCTACCTCCAAGAGCCCAGCCCTTGCCCACAGGGCCACACTCCACGTGCAGAGCAGC CTCAGCACTCACCGGGCACGAGCGAGCCTGTGTGGTGCGCAGGGATGAGAAGGCAGAGGC GCGACTGGGGTTCATGAGGAAGGGCAGGAGGAGGGTGTGGGATGGTGGAGGGGTTTGAGA AGGCAGAGGCGCGACTGGGGTTCATGAGGAAAGGGAGGGGGAGGATGTGGGATGGTGGAG GGGCTGCAGACTCTGGGCTAGGGAAAGCTGGGATGTCTCTAAAGGTTGGAATGAATGGCC TAGAATCCGACCCAATAAGCCAAAGCCACTTCCACCAACGTTAGAAGGCCTTGGCCCCCA GAGAGCCAATTTCACAATCCAGAAGTCCCCGTGCCCTAAAGGGTCTGCCCTGATTACTCC TGGCTCCTTGTGTGCAGGGGGCTCAGGCATGGCAGGGCTGGGAGTACCAGCAGGCACTCA AGCGGCTTAAGTGTTCCATGACAGACTGGTATGAAGGTGGCCACAATTCAGAAAGAAAAA AGAAGAGCACCATCTCCTTCCAGTGAGGAAGCGGGACCACCACCCAGCGTGTGCTCCATC TTTTCTGGCTGGGGAGAGGCCTTCATCTGCTGTAAAGGGTCCTCCAGCACAAGCTGTCTT AATTGACCCTAGTTCCCAGGGCAGCCTCGTTCTGCCTTGGGTGCTGACACGACCTTCGGT AGGTGCATAAGCTCTGCATTCGAGGTCCACAGGGGCAGTGGGAGGGAACTGAGACTGGGG AGGGACAAAGGCTGCTCTGTCCTGGTGCTCCCACAAAGGAGAAGGGCTGATCACTCAAAG TTGCGAACACCAAGCTCAACAATGAGCCCTGGAAAATTTCTGGAATGGATTATTAAACAG AGAGTCTGTAAGCACTTAGAAAAGGCCGCGGTGAGTCCCAGGGGCCAGCACTGCTCGAAA TGTACAGCATTTCTCTTTGTAACAGGATTATTAGCCTGCTGTGCCCGGGGAAAACATGCA GCACAGTGCATCTCGAGTCAGCAGGATTTTGACGGCTTCTAACAAAATCTTGTAGACAAG ATGGAGCTATGGGGGTTGGAGGAGAGAACATATAGGAAAAATCAGAGCCAAATGAACCAC AGCCCCAAAGGGCACAGTTGAACAATGGACTGATTCCAGCCTTGCACGGAGGGATCTGGC AGAGTCCATCCAGTTCATTCAACACCTGGTTAGAAAACTGGGGCCAGCACACAGGGGAAG GGTAAGCTGGTTTCATGATCGAATCAAGGCTCAGACAATTTTTAAAGGCCAGAGGGTAGA CTGCAATCACCAAGATGAAATTTACAAGGAACAAATGTGAAGCCCAACATTTAGGTTTTA AAAATCAAGCGTATAAATACAGAAGGTGGAGGGAACTTGCTTTAGACACAGTTCAGGTGA AGAAAGACCTGGAAACTTCTGTTAACTATAAGCTCAGTAGGGGCTAAAAGCATGTTAATC GGCATAAAAAGGCAATGAGATCTTAGGGCACACAGCTCCCCGCCCCTCTTCTGCCCTTCA TCCTTCTTTCAATCAGCAGGGACCGTGCACTCTCTTGGAGCCACCACAGAAAACAGAGGT GCATCCAGCACCACAGAAAACAGAGCCACCACAGAAAACAGAGGGTGACTGTCATCCCCT CCAGTCTCTGCACACTCCCAGCTGCAGCAGAGCAGGAGGAGAGAGCACAGCCTGCAATGC TAATTTGCCAGGAGCTCACCTGCCTGCGTCACTGGGCACAGACGCCAGTGAGGCCAGAGG CCGGGCTGTGCTGGGGCCTGAGCCGGGTGGTGGGGAGAGAGTCTCTCCCCTGCCCCTGTC TCTTCCGTGCAGGAGGAGCATGTTTAAGGGGACGGGTTCAAAGCTGGTCACATCCCCACC GAAAAAGCCCATGGACAACGAAAAGCCCACTAGCTTGTCCAGTGCCACAGGAGGGGCAAG TGGAGGAGGAGAGGTGGCGGTGCTCCCCACTCCACTGCCAGTCGTCACTGGCTCTCCCTT CCCTTCATCCTCGTTCCCTATCTGTCACCATTTCCTGTCGTCGTTTCCTCTGAATGTCTC ACCCTGCCCTCCCTGCTTGCAAGTCCCCTGTCTGTAGCCTCACCCCTGTCGTATCCTGAC TACAATAACAGCTTCTGGGTGTCCCTGGCATCCACTCTCTCTCCCTTCTTGTCCCTTCCG TGACGGATGCCTGAGGAACCTTCCCCAAACTCTTCTGTCCCATCCCTGCCCTGCTCAAAA TCCAATCACAGCTCCCTAACACGCCTGAATCAACTTGAAGTCCTGTCTTGAGTAATCCGT GGGCCCTAACTCACTCATCCCAACTCTTCACTCACTGCCCTGCCCCACACCCTGCCAGGG AGCCTCCCGTGGCACCGTGGGGACACAAAGGAACCAGGGCAAAGCTCCCTCAGCCCCATT CAAAGAGGCCTGGCCCACAGGCTCACGGAAAGTCAGCCTCTCATGCCCCGAGAGCTGAGT GCAAGGGAGAGGCAGCGCTGTCTGTGCTTCCCATGCAGAAGCACCCCCCTCCCACCCCTG TGCAGGCCGGCCTTCGCGGCAGACCACCATACACCACGTTCCAAGCCACACTGAGGCCTC CCTCCAAGCCTGCAGCCCCCATTTCCAGACCCTGCCAGGGCAACCTGCATATCCACCTCC CTACCCTGCCCCCCTCTTCCAGGAGTCTGCCCTATGTGGAGTAAGCACGTGGTTTTCCTC TTCAGCAACTATTTCCTTTTTACTCAAGCAATGGCCCCATTTCCCTTGGGGAATCCATCT CTCTCGCAGGCTTAGTCCCAGAGCTTCAGGTGGGGCTGCCCACAGAGCTCCTCAGTCTAA GCCAAGTGGTGTGTCATAGTCCCCTGGCCCCATTAATGGATTCTGGGATAGACATGAGGA CCAAGCCAGGTGGGATGAGTGAGTGTGGCTTCTGGAGGAAGTGGGGACACAGGACAGCAT TCTTTCCTGCTGGACCTGACCCTGTGTCATGTCACCTTGCTACCACGAGAGCATGGCCTG TCTGGGAATGCAGCCAGACCCAAAGAAGCAAACTGACATGGAAGGAAAGCAAAACCAGGC CCTGAGGACATCATTTTAGCCCTTACTCCGAAGGCTGCTCTACTGATTGGTTAATTTTTG CTTAGCTTGGTCTGGGGAGTTCTGACAGGCGTGCCACCAATTCTTACCGATTTCTCTCCA CTCTAGACCCTGAGAAGCCCACGCGGTTCATGCTAGCAATTAACAATCAATCTCGCCCTA TGTGTTCCCATTCCAGCCTCTAGGACACAGTGGCAGCCACATAATTGGTATCTCTTAAGG TCCAGCACGAGGTGGAGCACATGGTGGAGAGACAGATGCAGTGACCTGGAACCCAGGAGT GAGGGAGCCAGGACTCAGGCCCAAGGCTCCTGAGAGGCATCTGGCCCTCCCTGCGCTGTG CCAGCAGCTTGGAGAACCCACACTCAATGAACGCAGCACTCCACTACCCAGGAAATGCCT TCCTGCCCTCTCCTCATCCCATCCCTGGGCAGGGGACATGCAACTGTCTACAAGGTGCCA AGTACCAGGACAGGAAAGGAAAGACGCCAAAAATCCAGCGCTGCCCTCAGAGAAGGGCAA CCACGCAGTCCCCATCTTGGCAAGGAAACACAATTTCCGAGGGAATGGTTTTGGCCTCCA TTCTAAGTGCTGGACATGGGGTGGCCATAATCTGGAGCTGATGGCTCTTAAAGACCTGCA TCCTCTTCCCTAGGTGTCCCTCGGGCACATTTAGCACAAAGATAAGCACAAAAGGTGCAT CCAGCACTTTGTTACTATTGGTGGCAGGTTTATGAATGGCAACCAAAGGCAGTGTACGGG TCAAGATTATCAACAGGGAAGAGATAGCATTTCCTGAAGGCTTCCTAGGTGCCAGGCACT GTTCCATTCCTTTGCATGTTTTGATTAATTTAATATTTAAAATAATTCTACCAGGAAGCT ACCATTATTACCACAACTTCACAAATGAGAACACCGAGGCTTAGAGGGGTTGGGTTGCCC AAGGTTACAGAGGAAGAAAACAGGGGAGCTGGATCTGAGCCAAGGCATCAACTCCAAGGT AACCCCTCAGTCACTTCACTGTGTGTCCCCTGGTTACTGGGACATTCTTGACAAACTCGG GGCAAGCCGGTGAGTCAGTGGGGGAGGACTTTCAGGAAGAGGTGGGTTCCCAGTTGGTGA CAGAAGAGGAGGCTGCAAAGTGAAGGAGCAGGGGCTCCAGGTCTGGCGACAACCAGGGAA GGGACAGGGCAGGGATGGCTTGGACCACGAGAGGCACCTGAGTCAGGCAGTCACATACTT CCCACTGGGGTCTACCATGTGAGGCATGGTGTGGGATCCTGGGAAGGAGACCAAGCCTCA TTTCAGTTTGCTTATGGCCAAAGACAGGACCTGTGTACCCGACAACCCCTGGGACCTTTA CCAAAAAAAGAGCAAACACCATTCACTCACTCATGTTAGATAAACACTGAGTGAAGTCAC TGGAGCCCAAGGACTGTGCGAGGTCAGCACTGCCAATACAAGAAGCTGCAGCCCTCCAGC TCGCCTCCCTCAATGGCCACTCCGTGCTCCAGCCATGCTGGCTTCCTTTTAGGTCCTCCA CCTCCAGGCTGTAGTTCATGTGCTTCTTTCTGGAATGTTCTTCCCAACCTACCCACTCAA CCCTCAGACTTTACCATAAATGTCATTTCCTCACGTCTGCCTTCCCTGACCTGAGACCAA GCCAGGCTTCCCATGACGAGCCTCACAGTACCCCATCTCCCCTGAACAGATGCAGTAATA ACCTACATAACCCGGGGCCATGATCTATGGCTTTGAATCCTGGCTCTGTCACTAGGCCAG GTCTCTCAGCCCTTCTGTGCCTCAGTTTCCTCATCTATAAAATGAGATGACGGCAGTGCC TGCTCATGAAGTGTGAGTTAATGCACTCAAATCAATGGTTGTGCACGGTTTATATGAATA TTAGTGATTACAAAATATTATCAATAGACCTTGTCACAACTGTTATTGAAGAACTAATCA TCTATTGCTTATTTAGGTCTTTCTCTCCTGCCAGAATGTGCGCTCCAGGTGGAGAGGTAT GTTGCCTTATCCGTGGCTGGATATATAGAGATTCCCACACTGCCTTGCACACGAGCACTG CTGGGTAAATATTTGTTGGCTGCAGGAAAACGTGAAGGAATAGGCCCTCCAATGGGAGGA AAAGCATGAGTTGTGAGAGCAGAGCCACCACAGGAAACCAGGAGGCTAAGTGGGGTGGAA GGGAGTGAGCTCTCGGACTCCCAGGAGTAAAAGCTTCCAAGTTGGGCTCTCACTTCAGCC CCTCCCACACAGGGAAGCCAGATGGGTTCCCCAGGACCGGGATTCCCCAAGGGGGCTGCT CCCAGAGGGTGTGTTGCTGGGATTGCCCAGGACAGGGATGGCCCTCTCATCAGGTGGGGG TGAGTGGCAGCACCCACCTGCTGAAGATGTCTCCAGAGACCTTCTGCAGGTACTGCAGGG CATCCGCCATCTGCTGGACGGCCTCCTCTCGCCGCAGGTCTGGCTGGATGAAGGGCACGG CATAGGTCTGACCTGCCAGGGAGTGCTGCATCCTCACAGGAGTCATGGTGCCTGTGGGTC GGAGCCGGAGCGTCAGAGCCACCCACGACCACCGGCACGCCCCCACCACAGGGCAGCGTG GTGTTGAGACAACACAGCCCTCATCCCAACTATGCACATAGCTTCAGCCTGCACAGATAG GGGAGTAGGGGACAGAGCATTTGCTGAGAGGCCAGGAGCGCATAGATGGGACTCTGCTGA TGCCTGCTGAGTGAATGAGGGAAAGGGCAGGGCCCGGGACTGGGGAATCTGTAGGGTCAA TGGAGGAGTTCAGAGAAGGTGCAACATTTCTGACCCCCTACAAGGTGCTTGCTACCTGCC AGGCACCCTTTCCATACCTTGTCTCAGTTCAGCTCCCCACCTTGGATAAACAAGAAACCT TGGTTGCAGAGGAAAAAAGAGGCTGGAAACAAAGGGGTAGAAATGGGGTAGCAGGGGAGA TTGCCTGATCAACTGCCAAATGGTACACAGTTCTGGAAAAGCACAAAAAATGTGCACACA CGGGTTCTTCCCACTTTAACCCCTGAGGAATCTGAGGCCTGCTCCTGAAACAGACTGGGC AGTGGCTAGTGACTCTAGGTATAGGAGTATCCAGCCCTGCTCACCCAGGCTAGAGCTTAG GGGGACAAGAGGAAAGAGGTGCCTGTGGGGGTGGAGGACAGGAAGGAAAAACACTCCTGG AATTGCAAAGTGAGGGCAGAGTCTATTTATATTGGGTTTAATTAACTCCTCTCCCTGGTG CCACTAAAGCAGCAATCACACTGCAGACAGCACTGATTTGATTGGCAAGAGATGCACCAG GCAGAATATTAAGGGACCAGGCCCCTATAAATAGGCCTAATCACAGCCCCTCACTGGAAA ATGGTAAGGAAGACATTAATCAGGCCTGGCACTGTGCCCTAGACCTGCTCCCCTAGGCAC TACAGTGGGGCCCTTGGTTGCAACACAAGTAGGTAGGGATGGATGAGTGTGGCATGAAGG GCCTAGGAGATTTCACTTGGGTTTAAAATGCTGTGACCTTGAGTAAGTTGCCGTCTCTGA ATCTGATCCTTTCGATTTCCCATTCTCCAAACTGAGAACTAGCACTGCTGAGACGTGGTT ATTTCCAATAATAATTTGTATATTTTACATAACGCACCACACCAACATCTTCACCCAGTT GGAGCCTACTCCTTTGCTCCCGCTGCTGGCTTCCCCAGCCCTCCCTTCTGCCCTCCTCAG GCCAGCACTTTTCAGTGAGTTCCTCCTTTGCATACAGGCTTTCCAGATCTGTACTTGCCT TGAATACTCATCAGAGCCCAGGAGTTACTCCTCACCTCCCACTTATTTTTCCTCCCATCA AATAACTAAAGCATGGCCAGCTGATGCCCAGCCAACTGAGAAACCCAACCCTCTGAGACC AGCACACCCCTTTCAAGCATGTTCCTCCCTCCCCTTCTTTGTATTTATACTGATGCAAGT TTGCTGGCTGTCCTAACTTATTTCTGTGCCTCAGTTCTCCCATATGTAAGATCACAAAGG GGGTAAAGATGCAAGATATTTCCTGTGCACATCTTCAGATGAATTTCTTGTTAGTGTGTG TGTGTTTGCTCACACATATGCGTGAAAGAAGAGTACATACACAGATCTCCTCAAAAAGGA GGCAGCAAGCCCGTTCAAGAATGGGACTGAATACACCTGATGAGTGGTTTACTTTCTGTC TGCAAACATCTACTGATCATCTGTTAGGTGCAGGCCATGATCACAACAAAGACGAATAAG ACACTACACTAGCCAGGGAGAGTCTCAAAAACAACTAAACTCAAATTAAATTCATTCTAC TCCAGTCATGGGTACAAAGCTAAGGAGTGACAAATCCCTCTTGGAGTTAGGGGAGTCAGG AAAAAGCTCTTAGCAGAATGTGTGCCTCTCGGCCGGGCGCAGCGGCTCACGCCTGTAATC CCAGCACTTTGGGAGGCGAAGGCAGGCAGATCACCTGAGGTCGGGAGTTCGAGACCAGTC TGACCAACATGGTGAAACTCCATCTCTACTAAAAATACAAAATTAGCCAGGCGTGGTGGT GCATGCCTGTAATCCCCGCTACTCGGGAGGCTGAGGAAGGAGAATCACTTGAACCAGGAA GGTGGAGGTTGCAGTGTGCCAAGATCGCGCCATGGCACTCCAGCCTAGGCAACGAGGGTG AACCAGGTCCAGGAAGAAGGTGCAAAGACAGCATTCCAGGTAAAAGAAACAGCTTGAACA AAAAGTGTGTAGGGGAACCGCAAGCGGTCTTGAGTGCTGAGGGTACAATCATCCTTGGGG AAGTACTAGAAGAAAGAATGATAAACAGAGGCCAGTTTGTTAAAAACACTCAAAATTAAA GCTAGGAGTTTGGACTTGTGGCAGGAATGAAATCCTTAGACCTGTGCTGTCCAATATGGT AGCCACCAGGCACATGCAGCCACTGAGCACTTGAAATGTGGATAGTCTGAATTGAGATGT GCCATAAGTGTAAAATATGCACCAAATTTCAAAGGCTAGAAAAAAAGAATGTAAAATATC TTATTATTTTATATTGATTACGTGCTAAAATAACCATATTTGGGATATACTGGATTTTAA AAATATATCACTAATTTCATCTGTTTCTTTTTACTTTTAGAAATCACATATGTGACTTAA ATATTTCTTTTCTTTTTCTTTCCTCTCACTCAGCGTCCTGTGATTCCAAAGAAATGAGTC TCTGCTGTTTTTGGGCAGCAGATATCCTAGAATGGACTCTGACCTAAGCATCAAAATTAA TCATCATAACGTTATCATTTTATGGCCCCTTCTTCCTATATCTGGTAGCTTTTAAATGAT GACCATGTAGATAATCTTTATTGTCCCTCTTTCAGCAGACGGTATTTTCTTATGCTACAG TATGACTGCTAATAATACCTACACATGTTAGAACCATTCTGACTCCTCAAGAATCTCATT TAACTCTTATTATCAGTGAATTTATCATCATCCCCTATTTTACATAAGGAAATGGGGTTA GAAAGACCAAATAACATTTTTTCAACATCAAAACACTAGCTTGAGATCAAGCCCAGACTT GGATCTGTCGTCTGAATTCCAAGCTTTTTGTTATTTATTGATATGTTTTGTTGTTTTCAT GCAATAATGCAAATCTTAGCCCAAACATTTTGTTAGTAGTACCAACTGTAAGTCACCTTA TCTTCATACTTTGTCTTTATGTAAACCTAAATTAGATCTGTTTTTGATACTGAGGGAAAA ACAAGGGAATCTAACACTAACCAGCCCGTAGTGTGTGGTCAACACTTTCGTTACTTTAGT ATACATCACCCCAATTGTTTGTCTTCACCACACACTTTGGAGTTAGGTAGTAGTATCTAT TTTTACAAATAAGAAAACCCAGGCACAAAGGGGTTGATTAGCAATTATCTTTTGAAAAGC CTGTAGTTGCTCATCTGAAGAAGTGACGGACCACCTCTTATTTAGTGGACAGACAGTAAC TAGTTGAGAAGACAGGGGATTTTGTTGGCGGAAAAAAAAATTTATCAAAAGTCGTCTTCT ATCAGGGAGTTTTATGAGAAACCCTAGCTCCTCAGTTCCACAGTGGGTAACTGTAATTCA TTCTAGGTCTGCGATATTTCCTGCCTATCCATTTTGTTAACTCTTCAATGCATTCCACAA ATACCTAAGTATTCTTTAATAATGGTGGTTTTTTTTTTTTTTTGCATCTATGAAGTTTTT TCAAATTCTTTTTAAGTGACAAAACTTGTACATGTGTATCGCTCAATATTTCTAGTCGAC AGCACTGCTTTCGAGAATGTAAACCGTGCACTCCCAGGAAAATGCAGACACAGCACGCCT CTTTGGGACCGCGGTTTATACTTTCGAAGTGCTCGGAGCCCTTCCTCCAGACCGTTCTCC CACACCCCGCTCCAGGGTCTCTCCCGGAGTTACAAGCCTCGCTGTAGGCCCCGGGAACCC AACGCGGTGTCAGAGAAGTGGGGTCCCCTACGAGGGACCAGGAGCTCCGGGCGGGCAGCA GCTGCGGAAGAGCCGCGCGAGGCTTCCCAGAACCCGGCAGGGGCGGGAAGACGCAGGAGT GGGGAGGCGGAACCGGGACCCCGCAGAGCCCGGGTCCCTGCGCCCCACAAGCCTTGGCTT CCCTGCTAGGGCCGGGCAAGGCCGGGTGCAGGGCGCGGCTCCAGGGAGGAAGCTCCGGGG CGAGCCCAAGACGCCTCCCGGGCGGTCGGGGCCCAGCGGCGGCGTTCGCAGTGGAGCCGG GCACCGGGCAGCGGCCGCGGAACACCAGCTTGGCGCAGGCTTCTCGGTCAGGAACGGTCC CGGGCCTCCCGCCCGCCTCCCTCCAGCCCCTCCGGGTCCCCTACTTCGCCCCGCCAGGCC CCCACGACCCTACTTCCCGCGGCCCCGGACGCCTCCTCACCTGCGAGCCGCCCTCCCGGA AGCTCCCGCCGCCGCTTCCGCTCTGCCGGAGCCGCTGGGTCCTAGCCCCGCCGCCCCCAG TCCGCCCGCGCCTCCGGGTCCTAACGCCGCCGCTCGCCCTCCACTGCGCCCTCCCCGAGC GCGGCTCCAGGACCCCGTCGACCCGGAGCGCTGTCCTGTCGGGCCGAGTCGCGGGCCTGG GCACGGAACTCACGCTCACTCCGAGCTCCCGACGTGCACACGGCTCCCATGCGTTGTCTT CCGAGCGTCAGGCCGCCCCTACCCGTGCTTTCTGCTCTGCAGACCCTCTTCCTAGACCTC CGTCCTTTGTCCCATCGCTGCCTTCCCCTCAAGCTCAGGGCCAAGCTGTCCGCCAACCTC GGCTCCTCCGGGCAGCCCTCGCCCGGGGTGCGCCCCGGGGCAGGACCCCCAGCCCACGCC CAGGGCCCGCCCCTGCCCTCCAGCCCTACGCCTTGACCCGCTTTCCTGCGTCTCTCAGCC TACCTGACCTTGTCTTTACCTCTGTGGGCAGCTCCCTTGTGATCTGCTTAGTTCCCACCC CCCTTTAAGAATTCAATAGAGAAGCCAGACGCAAAACTACAGATATCGTATGAGTCCAGT TTTGTGAAGTGCCTAGAATAGTCAAAATTCACAGAGACAGAAGCAGTGGTCGCCAGGAAT GGGGAAGCAAGGCGGAGTTGGGCAGCTCGTGTTCAATGGGTAGAGTTTCAGGCTGGGGTG ATGGAAGGGTGCTGGAAATGAGTGGTAGTGATGGCGGCACAACAGTGTGAATCTACTTAA TCCCACTGAACTGTATGCTGAAAAATGGTTTAGACGGTGAATTTTAGGTTATGTATGTTT TACCACAATTTTTAAAAAGCTAGTGAAAAGCTGGTAAAAAGAAAGAAAAGAGGCTTTTTT AAAAAGTTAAATATATAAAAAGAGCATCATCAGTCCAAAGTCCAGCAGTTGTCCCTCCTG GAATCCGTTGGCTTGCCTCCGGCATTTTTGGCCCTTGCCTTTTAGGGTTGCCAGATTAAA AGACAGGATGCCCAGCTAGTTTGAATTTTAGATAAACAACGAATAATTTCGTAGCATAAA TATGTCCCAAGCTTAGTTTGGGACATACTTATGCTAAAAAACATTATTGGTTGTTTATCT GAGATTCAGAATTAAGCATTTTATATTTTATTTGCTGCCTCTGGCCACCCTACTCTCTTC CTAACACTCTCTCCCTCTCCCAGTTTTGTCCGCCTTCCCTGCCTCCTCTTCTGGGGGAGT TAGATCGAGTTGTAACAAGAACATGCCACTGTCTCGCTGGCTGCAGCGTGTGGTCCCCTT ACCAGAGGTAAAGAAGAGATGGATCTCCACTCATGTTGTAGACAGAATGTTTATGTCCTC TCCAAATGCTTATGTTGAAACCCTAACCCCTAATGTGATGGTATGTGGAGATGGGCCTTT GGTAGGTAATTACGGTTAGATGAGGTCATGGGGTGGGGCCCTCATTATAGATCTGGTAAG AAAAGAGAGCATTGTCTCTGTGTCTCCCTCTCTCTCTCTCTCTCTCTCTCTCATTTCTCT CTATCTCATTTCTCTCTCTCTCGCTATCTCATTTTTCTCTCTCTCTCTTTCTCTCCTCTG TCTTTTCCCACCAAGTGAGGATGCGAAGAGAAGGTGGCTGTCTGCAAACCAGGAAGAGAG CCCTCACCGGGAACCCGTCCAGCTGCCACCTTGAACTTGGACTTCCAAGCCTCCAGAACT GTGAGGGATAAATGTATGATTTTAAAGTCGCCCAGTGTGTGGTATTTTGTTTTGACTAAT ACAACCTGAAAACATTTTCCCCTCACTCCACCTGAGCAATATCTGAGTGGCTTAAGGTAC TCAGGACACAACAAAGGAGAAATGTCCCATGCACAAGGTGCACCCATGCCTGGGTAAAGC AGCCTGGCACAGAGGGAAGCACACAGGCTCAGGGATCTGCTATTCATTCTTTGTGTGACC CTGGGCAAGCCATGAATGGAGCTTCAGTCACCCCATTTGTAATGGGATTTAATTGTGCTT GCCCTGCCTCCTTTTGAGGGCTGTAGAGAAAAGATGTCAAAGTATTTTGTAATCTGGCTG GGCGTGGTGGCTCATGCCTGTAATCCTAGCACTTTGGTAGGCTGACGCGAGAGGACTGCT TGAGCCCAAGAGTTTGAGATCAGCCTGGGCAATATTGTGAGATTCCATCTCTACAAAAAT AAAATAAAATAGCCAGTCATGGTGTCACACACCTGTAGTCCCAGCTACATGGGAGGCTGA GGCGGGAGGATCACTTGAGCTTGGGAGATCGAGGCTGCAGTGAGCTATGATTGTACCACT GCACTCCAGGCTGGGCGACAGAGAGAGACCCTGTCTCAGAAAAAAAAAAAAAAGTACTTT GTAATCTGTAAGGTTTATTTCAACACACACAAAAAAAGTGTATATGCTCCACGATGCCTG TGAATATACACACACACCACATCATATACCAAGCCTGGCTGTGTCTTCTCACAAATGCAC TGCTAGGCACCACCCCCAGTTCTAGAATCACACCAGCCAGTTCACCCTCCAGATGGTTCA CCCTCAACTTCATAAAAGTTCCCTACCTAATCTACTGACAGGCTCATCCCCGACCTAATT TTAAAGATTTCCTAGGAGCTGCAGTGGGAATCCTGGACCTCAGCCTGGACAAAGAACAGC TGCAGGTCATTCTCATGTGTGGACACAGAAGCTCTGCCTGCCTTTGCTGGCCAGCTGGGC TGAGCGGGCCTGGGAATTAAGGCTGCAGGGTTGGTCCCAGGCAGTCTTGCTGAAGCTTGC CACATCCCCCAGCCTCCTGGATTTGCCAGGATCCAAGAGCATGGACTTTAGGAATTCCTG GTGGAGGAGTGAAGAAAATGTGACAGGGTGTCCTAAGCCCCGATCTACAGGAAGAAAACT GGAAATAAGACTGAGGACTTAGTTTAAGATGTTCCTACTCAGCCTCTAGCTTTTGTGCTA CAGTTCTGGGAACAGACTCCTCTCTCCTGAAAACCACTTCCCTCCGCAGCATTAGATTTC ACCAAGATGTCTTGCTTGTGGGAAAGACTTCCAAGGATGCCTGGAGAGAGGAGGATGGAA ATGTCCTGCTCTCTAAACAGATAGACAGATGCAGCCAGACAGAAAATAGTTTATCTTGCT GAGGTTTCTAATGTATTTGAAAGAGGCCTGGGTCTAGAAGTCTACCCAGAGGGCTCTGTG TTGTGCACGCAAAGATAAGAACCTTCCCTGTGGGAGTTCCAGAGCCAGTTTTCATAAACA CCCATCGGTGACTGTGTTCAGAGTGAGTTCACACCATCCTGACCTGCCCTGAGTTAGACC TTACATGGTCTTCCTCCTCTAGGAAGCCTCTGCAGCCCAGGAACCTCCCCTTATCGGAAA TGAACAGCATTTGAAGCTTCACCAGACAGACCAGACAGCTTAGCCCTCGTGTTGTGCCAT GTGGGTTGTTCTCTGAGAGGCAGGAGAGCATAGTGGTTACTAGGAAGGGAAGGACTTTGG GACTAGACTGCCTCGGCTGGAGTCCTCTTTCTGCTTCATAGCCACGTGATCCTAGGCATG TTACCTGTGCCTCAGTTTTCACTCTGTCAATATGTAATAACTGAATCTGTCTTTGTGGTG AGGATTCAGTGAGTTAACATATTTGAAGTGCTTAAAAATGAGGCTTGTGTCCATAGATTA ATGAGTGAATACACAAATGGTGATATGGACATACAGTGGAGTATTAGTCATAAAAAGGAA GGCAGAGCTGATCCATGGCACCATGTGACAGAACCTCAAAAGCATTAGGTTAAGTGGAAG AAGCCAGACACAGGTCACCTATTGTGTAATTCCATTTATAGGAAATATACAGAATATGTA AATCCGTGGAGAAAGAAAGCCGATTTCCAGGGGCTAAGGGGAGGGGAGAATGGGAAGTGG CTGCTTCATGGGTACAAGGTTTCATTTTGAGCTGATGAAAATGTTTTGGAACTACATAGA GATAGTGTTGGCACAACATGGTGAATGTACTGAATGCCACTGATTGTTCAATTTAAAATG GTCAAACTTATATGAATTTCACCTCCATTAAAAAAAAAAAAAAAGGACCAGATGTGGTTG CTCACACCCATAATCCCAACACTTTGGAAAAAGGTGAAAGTTTTTTTTTCTTTTTTTTTT TATATACTTAAGTTCTAGGGTACATGTGCATAATGTGCAGGTTGGATACATAGATATGCG TGTGCCATGTTGGTTTGCTGCACCCATCAACTTGTCATTTACATTAGGTATTTCTTCTAA TGCTATCCCTCCCCCAGCCCCCCACCCACTGACAGGCCCCAGTGTATGATGTTCTCTGCC CCATGTCCAAGCGTTCTCATTGTTCAATTCCCACCTGTGAGTGAGAACATGCAGTGTTTG GTTTTCTGTCTTTGTGATAGTTTGCTCAGAATGATGGTTTCCAGCTTCATCCATGTCCCT GCAAAGGACATGAACTCATCCTTTTTAATGGCTGCATAGTATCCCATGGTATATATGTGC CACATTCTCTTAATCCAGTCTGTCATTGATGGACATTTGGGTTGGTTCAAAGTCTTTGCT ATTGTGAATACTGCCACAATAAACATACATGTGCATGTGTCTTTATAGTAGCACGATTTA TAATCCTTTGGGTATATACCCTAAGACCTGGGACGCATTTAAAGCAGTGTGTAAAGAGAC ATTTATAGCACTAAATGCCCACAAGAGACCTCTGCCTGAGAACGTGGGTTTCAGCCTAAG AGTTGTAATATGTGTGCCCATTCACAGGTGCTGCATCAGAGTCCCAGGTGGGAAGAAGGC AAGCATACACAAAAATGGTAAAAGGCAGAAAGGAGCCCAGTCTCGTTCTTTTTAAGAAGT TTTCCTAAGAATCTCCACCCAGCGACTTGCTCTCACATCTTCTTGGCCAGCACTGGACCA CACAACTCCTTCTAGATACAGAGGAGTCCTAGGATTCTATGAGAAAGAAGGGGAGGGTGG GCAAAGGGCAGCCAGCTGTGCAGCATCTGCTGGAGACACCTAACCCTTGGTGGAGGGGTT GTGGTGCTGGGAGAAGGCTTTCTGGACGGTGTGACAGCAGAGATAAACTTAAAGGCCAAG TAGGAGTTACCCTGGTGAAGCAGGGCAGGGTTACAAGCATTCCAGCAACATGAAGCAGCA GGAGTGTTTTAATTAAAAGAAGGCAGTTGCTGTAACCAACTATAAACAAATAAAGGCTTA AACACAATGGAAGTTTATTTCTCACTAAGGGAACATCCAAATCCATGATACTTTAAGTCA GGGACCCAGGTTCCTCCCATCTATGGTTCTGCCATCACTAATCTGGGTCTTCCACAATTG CCGTGCTCCTTGGAGGTGGGAAGAGCAGGCGGAGGACACGTGGGAGGTTTTAGGGACAAG CCTGGAGGCAGCATGCGTCACTCCCATGCAGAGTCCATTGGCCAATGCTGGCTCCGATGG CCACATCTCACTGCAGGGGCAGCTGGGAAATACAGTCTGGCTGTCTACCCAGGAGGAAGA GCAGCCAGTTTCTGCTGCTGATGATCAGGAGGTGGAGAAAATGTTCAGTCAGGCAGGGAG TGGGAATAGACAAGACCACAAGCAGCTTGGTGCCTCTGAAAGGGAGAGGGGTGGAGGGGA GACTAGAGAGGTGGGTAGGAATACTGGATTCCACTGACCACGTGCTGGATGTCACGCTTA GCCCTCCTGCTCTGTGCCGGGTTAGGCACCTGGTGTTTTACGTACATAATCTCAATTCTG TGAGGGCATCCGACCTGTGGGAAAAGAGCTGTTTGTTTCAAATGCCAGTCCTGCTTCCTA ACAAGTGTTTAGAGCTTAATCGTGTTCAAAATACATATACAATGTTTAATACTTACAAGA ATTTGGTGGGGAAAATATTACCATCTTTCCCTTTTGTGATTGGAGAAAAATGAGGCTTTG AAGGGTTTAAGAACTTGCCCAAGGTCGGCCAGGTGCAGTGGCTCATGTCTATAATCCCAA CACTTTGGGAGGCTGAGGTGGGAGGATCGCTTGAGGCCAGGAGTTCAAGACCAGCCTGAG CAACATAGTGAGACTTTGTCTCTATAAAAAATAAATAAATAAATAAAAACAACTTGTCCA AGGTCAGACAGGCAGCCTCTTAGTAAGCACACATATCCTCTATATTATACTACCTCTCAT GGAGGATCTCCTGTGTTCTACAAATAGTCTGGACTTGAGCCAGAATGTGTTATAATCCTG GGATCACGGCCAGTGGGCTTAGAAGAAGCCATCTCTTTCTCATGCCAAGATGAGGCTCCC CCAGATTTGCTCAGACTTACCTATAGTCAGCAGCATCGGGGGTCAGGAAAGACTTCACGA AGCCATAAATGCATCCTTCTCGGGGCAGCACCTGGCTCTCCCAGGTGAGAGAGGACTCCA TTTTCACAGGCAGGCGTGGGAGCTTCAGCACCCATCTCTGGGCCCAGAATGACCCACTGG AGACCTTACAGCTCTCCTGTCACCCCCAATTCCTGCCCCCTCTGCAGCCTTGGAGGAGAA TGGAGCTGAAGGGCCTGCCCTCTGTAGGGTGAGAAAGGGAGGCTAAAGCCTGGTGCCCAC TGCCCTGGCTGCTCCGCATTGCAGGAGCTGCGCCCTTCCTTTCCTGGCACAGGGTCCACA GCCCCGAAACCCCGTTGTGTGGGAGCTGGGCACAGGGCAGCAGGACTAATCCTTGGAACA GCTCAGGGAGGATTATCCCAGCCACTGTCAGCAGCGGTGCAGCTGGCTCATTCCCATATA GGGGGAGGCCAGAGCCAGGGGCCTGCCACAAGTTGGAAGGCTGGGGAAGGGGAGGCCAGC AGAGGTGTCCTGGCTGTGGGTGGCTCTGAGGGGGCTCTCAGGGGTGGGGCTAAATCTCAG GGGCAGGATTATGTAAATCAAACCAATTCTAGCCACAGATTTAAAGTTTGGAAAAAAAAA AAAACCCAGCCTGGCGGAAAGAATTTAAATTATAAAAACTTAGAAGTATGGAATGTGAAA TCATCCTGTAGGTGCTTATTTAACAACGAAATCATCCCGACACAATGAGCCATATGTGAA AAGTCATCCTTCCCCAACACATCCCCCAACAGGCACTCCTCAAGCCTCTCCCACCCAAGT GCTGGCATCCTCCCTGTCCTGCTTCACCTGAGACACCCCTTGTCTCATTAGACATGCAAC TACGGGAGGGGTGACAGGAAGACAAGACACTATTTCCTCAGGCCCAGTTTGGTGTGGGGA GAAAGCCTCCTGATCCTGAAAGCAAGAATTTGACCAGAGCAGAAGTAATCAGTATGCAGA TTGATTCTGTGGTATGTTAATGTTTATGCATAGATTATGAGGACCAGGTGAAAAGTGGGC CAGGGGAGCCAGATGTGTGTGTGAGTCATGGGTGGCTGAGATGAGGACAGGAGGGAAACT GGTTTGGAGGGTGCTGGCGATGGGGTGGGGGTGCCAGGAGGAAGGGAGGCTAGTTGTTTG AATGTCTGCATGAAAAAGCGGACGACAGCGGGGTCTGGGTGAATTCGGGCAACCATTTGG ACCGTGGAGAAAACTGCCTGCGTGCGGCTGAGGACCTGCACTATTAATTTGTTTTTTAGC TAAGGCAAAGATAAATATAAAAACTGATACTCCACCCAGTTACCAGAAAACATTTAGGTA TGTGTGAGACAACTTGGGTATGTGAACCTACCTTTTCAATGTAAATTCAGTGAAATCTAA GTGCAGATCCCATATTTCCAATAAAAAGGTAACATCCAAACTCAGATGTCCTATGAGTAT AAAATACACAAAGATCTTCTGGACTTAGTATGAAAAGGGATTTTTTTTTTGTCAGGTACC TCACTAGTTATTTTTAAAATAGGATTGCATGTTGAAATGATAATCTTTTGGATATATTGG GTTAAATAAATTTATTATTAAAGTTAATTTCACTTAAAAATGTTTAATGTAGCTACTAGA AATTTTAAAATTAAGCATGTTGCTCACCTTATGTTTCTATTGGACGGCTCTCTCTAGATA CAAAGGCTGCCAAGAGGGACCTCACTCTAGCTTCAGGGAGAAGAGAGGAATTAGCAAGGC CAAGCAGAGGCTCCTGAGGGCAGGGCCAAGGGCGGCTTGGTGGGGTGGGGATGGGATGCA CAGAGATAACTCCAACCCTTAAGAAGGTGTTTCCTAGAGCAGGCTGTGACCTGTCAGTTT ATATACTGAGGCTTAGGAGCCTCTTGGATGCCCCCAGATCTGCACCCCTGAATTGCCCTG TGCCCCTGCCGTCTTTGTTCCTGTGCTGGCATAGTGGTCTCACCTCCGGCAGTATCACCA CCACTGGGCACAAGCTTCTCCAGCACAGCAACTGTGTCTTATTTCTCCTTGTACTCCCAG TGTTCACACCATGCTGCACTCACAGAAGACTCTTCGTTGATATTTTGTGGACAGAGAGAA TGCCTGTGAGAGTGGGCTGAAGTGTGCGTTGGGCTCCAGAGACCTTAAGGAGGGGAGACC AGGTCCTGAGTAAAGTTGAAGGGGAGGGGCTGAGTCCTGCTAGCCAGGAGTCTCATCCCC TGGGGAAGTTCCAGGGACCCCTCAGAAGTGCAAGGGGACGGTGTTAGTGTTAGTCCAGTA ACACAGCCCAGAGCCTGCCTTCCACGTGGGTTTGACAGGAGCCTCCTAACTGCTCTTCTG CTTCCATTTTTGCCCCTTCAGTCTATTCTCAACAGGGAAGCCAGAGGCATCCTTAACCAT GTCAGATCATGTGGCTCCTCAGCTCAAAGCCTCATCTCAGAGGAAAGCTCTGGTCCCTTA GAAATGGCCCAAGTGGTGACAGACAGACTCTAAGGTGAGCAGACTGTTGCTAGATATCTG GGCTCGGAGGACTCGCCACTGCTCAAAGGCAGTGAGGATTTTCGCACTAGAAGCTGGAGG ACAGGGATCCTTGTTAGGTAGGAGCAGAAAGCTTAGAAAAGTGGTCTCCTGCAGTTACGT GGCAAACACATCATGTAAGTGATAAATTGGGTATGCAGTTGAGGAGATTTCCAAGTAAAA TGTTGAGGATGCTGCCTGGTTTCTTCTTACTGCTTATAATATAGTGTGAGAGAAGAGAGA TAAATTGAGAAAGAGACTGGTTTTTAAACTGTTAAAATTGAATCAGGACTTGATGATTTT GAAAATTGTCAGTCTCCCCACATGGAAAAAGATGCTGAAATTAACAAATGGCTTCTGAGC ATGTGGCATAGGGTGTAACTGTACAGTCTTTTGTGATTATGCATAAAGATCAAAGGATGG GAGTAGCAATGAGTCACACAGAGGTCTGTTGCAAGAGATTACAAGGGTGTACCATGCAGA ACCTCTCCACCAAACCTTAGGGCCCTTGGGAAGCTTCAGTGAGTTACCCTGGGGGCCATC TTGGCAGGAGCTGAAGGTAGAAAGGTAGAGTTTATCTCTAAAAGATTCATGGGTATGGCT CTTGACAAATCGACTATGAGCCCCACCGAAACCCACAGAGGACAGGCAAAGGGTTTGGGA AAGCTGTTTCACCCACAGTGCTGGCAGATTGGTCTGTAGGGGACAGAGTGCAAAATGAAA GAAGACTGTCAGAGACCCCAAACTCTGCTGTCAAGAAGAAGGCTGATAAAACTACTTGGC TGCAAACACGTGGATCTTTCGTGAGAAAAGAAGGATGACCCAGAGGCAGAAGCCCAGAAG GCAGAGCCAAGAGACATGGAATCTTCCCACATCTTAAAACCTGTTTAGGGAACACCAGCA TCTGTCCAGCTGGATTTCAGAACCACCATTCCTTCATCCTTCCCCTGCTGCCTCTTTCTG AACAGCAATGTCTCAAGCTTTACCCACCATTGTGTGTTGCATATGTAGGGGGCAGATAGC TTGTATCTTTAGTTTTCCAGATCAGAGGAACATCCAAAGAAATCTGTTCTACACCTAAAC CCGATTTAGATGAGATTCGGGACTGTGAGCATGAAGGGATCTCAAGAGGGGTGAATGTGT TTTGCATGCACAAGGGACAGGAGTCTTGGGGACAGAGGACAGGCTGTGGTGGCAGATACT AAGGTGACCCCCACAACCCCCACCTCTGCCATTCACACCCTTGAATAATCCCCTTCTCTG GTTGTAAGCAGAACCTGTGGCTTGCTTATGAAGGAGGCGGTATATATGTGATTCATGTAC TGATCATATTGTATAAGATCACTGGCTGGATGCAGTGGCTCGTGCCTGTAATCCCAACAC TTTGGGAGGCTGAGGCGGGTGGATCACCTGAGGTCAGGAGTTCGAGACCAGGCTGGCCAA CATGGCAAAACCCCGCCTCTACTAAAAATACAAAAATTAGCCAGGCATAGTGGTGCACGC CTGTAATCACAGCTACTCAAGAGGCTGAAGCAGGAGAATTGCTTGAACTCAGGAGGTGGA GGTGGCAGTGAGCCAAGATCGTGCCACTGCACTCCAGCCTCAGTGACAGAGCGAGACTCT GTCTCAAAAAATAAATAAATAAAATGTTAAGATCATAACCTGTCTTTCTGGGGACTCTCT CTTGACGCCTTTGAAGAAGCAGGCTGCCATGTTGCAAGCTGCCTCATGGAGGGGATCAGC TGCGAGGAGCTAAGAGCCCCCTCCAGTCGATGCTCACCAGGAAGCTGAGGTCTTGTGTCC AGCACCCTGCATAGAACTGAATGCTGCCATGTGAGCTTGGAAGCAGAGCCATCCACACAG CTGAGCCCTAGATGAGAACCCAGTGCTGGCTGACACCCTGATGGCACCTTACAGAGGACC AGTTAGGCTGTGCCAACTCCTGACCTGCAGAAGCTGGGGAACACTGGGTCGTATTTGCAG CTGCTGGATTTGTGGGAATTTGTCACACAGCAATTGGGAGTCACACAGCCTGTGACGCCC CAACAATCCACACCTCCTGCATCTCCCTGCCTTCACTTCCTAGCACACTGCCCTGACTCC CTCTGCCGCAGCCACGCTGGCCCTCTGCTGTTCTTCGAAGCCACCAGGGCTGCATTGGCT CCCAGCCTTTGCTCTCACTGCTTTCTCCTCCTAGAGAGCCCTTCCTGCATGTATATGTTT GACTCACTCCCTTGCCTCCTTCAGACTTGTACTTAAAAATCTCAGTAAGCATTTCCCTGG CTACCCTTTTAAAAATTGCAACCCACTTCCATCCCCATCCCCAACATGCCATATTTCCTT TCTTCTTCTTCCTTCTTCCTTTTTTTTTTTTTTTTTTTGACACAGGTTCTCTGTCACCCA GCCTGGAGTGCAGTGACATGATCTCGGCTCACTGCAACCTCTGCCTCCCCAGGCAAGAAA AGGGGAGGATGCCAATAAAGGATGCATTGATTTGTATTTACTACAGTGGACATCAAGGGC ACATTCTTGCTGTGGCCATCAAGAGACTGTATAAATTCTATGACTTGTAGTTGTCCCACT TAAGAAACAAAGAAGCTGTGCATTTCTTTACTGGTCTAGAGCTGCTCTAGGGCATTTTCT CTACAGCAATTCTAGGTTTCCCCACCTTGTGAGTTTAGCTTTTTCTATATTCAAAGAAAA GTCCTCAGCCAGAGATTCTCAGGAGCTTATAGAACAATCCAAACTCTTGGGAATATTAAG TGGAGAGGGGTACGTGCAAGACACCAACAGCACTAGAAACAGTCCACATCTTTCCATGCG TGGAGGAGTTTATGCTCTATGTGAGTTCACTCCATCATTAATTCTTCAAACACAAGAGTG TTAAAGGAACAAGAGTTAATGGGTCCTGTCATTACACTTGTTCCCAGGATGACATTCTTC ATCTTCCTCTTCTACAACCTGTTCTATATTCCCCTCATGTTTATCCAGTGCTTCTGCTAG TCTAGTTCACTTCCAAAGACCCATGATTACCATGGCCCTGTCAGGCTGTAATTGCTGCAA TTTCCAATTTACAATTGTCATCATCTATGGTTGATAAAGGTATAGCAATATTTCTATTTC CTCATGATAATGAAGGTCAATTACAACTGCCAGTATAATAACTTATTTCTTTGTCTGCCA ACCTACATACACAAGGAAGCCAAAATGACAGGGAGCTACTAAAACTTTATTCTTATTGGA ATGCTTACTATGTACCCAGAAGAAGCATTCTCCCTACTCCAGCAGAGCTTAATGCTGTAG GTCCAGGAAGCTCAAATTCTCCAAGGGAGTTTTAGTGAGAGGAGCCACTCTCACCCTCTG CCCTTGGTTTACAAACCTGTATATTCTAGGACCCAATATCTTACAATGTCCATTGGTTCA AAGTATAACATGTTAAAGCACAGAGCCCCAACTCTGAAAAGTACCATCCCTAAATTGGCA TTTAGTTGCACCTTTATATCCACCTTTAAAAGAAATATCTTTTAATGTTCTATCAGACTG ATAGATTCTGTTTAATATAGTATATTATAGCACCAGTGGATCATTTGGTTGTATGCATAT TATTGTACCTTCTCTGCTACAAAATATATTCCTTTGTCCTAAGGTGTGTTACAAAGAACA TTAGGCATTCTATGCATCTTTGGATAGTTTAATGGCCAAGACATTGATGGCAGGAGAGTC AAAGCCACAGGTGGAAAACACATTTATCCCAGTAAGAACAAATTGCTATTCTTCCACTGT AGAGAGGGTAAACAATGTGCCATTACGTTGCCAATTGAATGCCTCAATCATGTCAAGGGC TGAACATCTATGACTGTTTCTGAAAGGTCAAACATTCAACAGAGGCTGTAGCTAGAACTG CCTTAATGATAAGAGATCATGCTGAATTACCCATGCAAAACCTTAATACTTGACACTTAT CACTACTTTATTCAAGAGCCTATTGTGCAAGCATAAGTGGCTGAGTCAGGTTCTCAACTC TGCTCATTAATACTATGCTTGGAGTATACAGTAAGATAAGAAACATAAATAAGAAGTGTA CATTTGTTTCTTCCTGTTTTCTTCTGGCTATTGGATCAATTACATCCCATCTTAAGCTGA CCCCTGTGTAATTAATCAATATCCGTTTTAAGCAGCAATCCATAGTTGTGCAGAAATTAG AAAACTGACCCACACAGAAAAACTAATTGTGAGAACCAATATTATACTAAATTCATTTGA CAATTCTCAGCAAAGTGCTGGGTTGATCTCTATTTACGCTTTTCTTAAACACACAAAATA CAAAAGTTAACCCATATGGAATGCAATGGAGGAAATCAATGACATATCAGATCTAGAAAC TAATCAATTAGCAATCAGGAAGGAGTTGTGGTAGGAAGTCTGTGCTGTTGAATGTACACT AATCAATGATTCCTTAAATTATTCACAATAAAAAAAAAGATTAGAATAGTTTTTTTAAAA AAAAAGCCCAGAAACTAATCTAAGTTTTGTCTGGTAATAAAGGTATATTTTCAAAAGAGA GGTAAATAGATCCACATACTGTGGAGGGAATAAAATACTTTTTGAAAAACAAACAACAAG TTGGATTTTTAGACACATAGAAATTGAATATGTACATTTATAAATATTTTTGGATTGAAC TATTTCAAAATTATACCATAAAATAACTTGTAAAAATGTAGGCAAAATGTATATAATTAT GGCATGAGGTATGCAACTTTAGGCAAGGAAGCAAAAGCAGAAACCATGAAAAAAGTCTAA ATTTTACCATATTGAATTTAAATTTTCAAAAACAAAAATAAAGACAAAGTGGGAAAAATA TGTATGCTTCATGTGTGACAAGCCACTGATACCTATTAAATATGAAGAATATTATAAATC ATATCAATAACCACAACATTCAAGCTGTCAGTTTGAATAGACAATGTAAATGACAAAACT ACATACTCAACAAGATAACAGCAAACCAGCTTCGACAGCACGTTAAAGGGGTCATACAAC ATAATCGAGTAGAATTTATCTCTGAGATGCAAGAATGGTTCAAAATATGGAAACCAATAA ATGTGATATGCCACACTAACAGAATAAAAAATAAAAATCATATTATCATCTCAATAGATG CAGAAAAAGCATTAACAAAAGTAAACATTCTTTCATAATAAGACATCAGATAAAACAAAT TAGGAATAGAAGGAATGTACCGCAACACAATAAAGGCCATATATAACAAGCCCACAGCTA ACATCATAATAGTAAAATCATCACACTGGTAAAAAAAATGAAAGCTTTTCCTCTAAGGTC AGAAATAATATAAAGGTTCCCACTCTTGCTATTTCTATTCCATATCGTACTAAAAGTCCT AGCCAGGACAATTAGACAAAATAAAAATAAAAACACCCAAATTGGAAAGATAGAAGCAAA CTTTTCTGTTTACAGATAACATAATCTTATATGTAGAAACCCCTTAAAACTTCAGCAAAA AAAAAAAAAAAACTACAGAGCTAGTAAATTCAGTGAAGTTGCAGAATACAAAATCAACAT ACAAAAATCAGTAGTGTCTCTATACACTAATAAGGACTTAACAGAGAAAGAAGTTAAGAA AACAATACCACTAACAATAGAATCCAAAAAATAAAATACTTAGGAATAAATTTTACCAAA CATCTGTACACTAAAAACTATAAAACATTGAAAAAAGAAGTTGAATAAGACACATATAAA TAGAAAGCTATCTCATGTTAATAGATTAGAAAAAGTAATATTGTTAAGATGTCCTCACTA CTTAAAGCAATTTATAGATCTAATGCATTTATTGCAATCTCTTCAAAATCCCAAAGGTAT TTTTGACAGAAATAAAAAAAAAATTCTAAAATATGCATGAAACCACAAAAGACTGTGAAT AGCTAAAGCAATCTTGAGCAAGATGAACAACACTGGAAGCATCACACTACCTTATTTCAA AATCTACTACAAAGCTATAGTGATCAAAGCAACATGATACTGTCATAAAAACACACAGAT AAACCTATGGAATGGAATAAAGAGCACAGAAATAAGTCCACACATTTACATTCAATTGAT TTTCAACAACAATGTCAAGAAGACAATGGGGAAAAGACAATCTCTTCAATAAATGATGCT GGAAAAACTATATATCCACATGCAGAAGAATGCAGTTGAATCCTGATTTCATACCATATG CAAAATTCAACTGGAAATGGATTAAATACAAATTTAAAACATGAAATGGTATAACTATTA GAACAAAACATAGAAAATATTCTTCCTGACATTGGTTTGGGCCATCATTTTTCTGATATG ACTCTAAAAGCACAGGCAAAAAAAGAAAAAATAGACAAATGAGACTATGCCAAATTAAAA AATTTCTAACAACAAAAGAAACGATCAATAGAGTGAAAAAGATAACCTCTTGAATGGGAG AAATATTTGCAAACTACTCATCCAACCGGGGATTGATATCCAGAATATACAAGTAACACA AATATGTCAAAAGTAAAATAAATAAATAAATAAATAAATAAATAAATTAAATAAATTATT TAAAAATCGGCAGAGGACAGGAATAGACATTTCTCAGGAGACAACATACAAAGGGCCACA GATACATCAAAAAATGCTCAACATCACTATTTGTCAGGGAAGTACTAATTAAAACCAAAA TGAGATGTCCCCTCAAACCTGTTAGAATGGCTATTATCAAAAAGATGAAAGATAGCAACT ATCAGAGAGGATGATAGAAAAGGGAACCCTTGCATCATGTACAAATTAAAAATAGAACTA TCACATGATCCAAGAATCCTACTTCTGGGTATATAGCCAAAGGAATTGAAATCAATATGT CAAAGGGATATCTGCACTCCTATGTTATTGCAGCATGTTCACAATGGCCAAGATATAGAA TCAACCTAACTGTTCATAGACAGATGAATGGATAAATGAAATGTGATATGGAAAATTATT CAGCCTTAAAAACAGTAGGAAATTCTGTCATTTGAGACAACGTGGATGAACCTAGAGGAC ATTAAGCTAAGTGAAATAAGCTAGACACAGAAAGACAAATATTGCATGATCTCACTTAGA ATCTAAAAAATCTGAACTCATAGAAGCAGAGAATAGTATGATGGTTACTAGGGTTATCTG GCAGGGAGAGGATGAGGAAATGGGACATTGTTAATAAAAGGAAAAAAATTCAATTAGTAG GATTACATTCAGGGGACCCAATATACGACATGTTGACTGTAATTAATAATGTATTGTATG CTTGAAAATTGCTAATACAGTATATTGTAAATGTTAATATGAGGTAATATATGTGTTAAT TAACTTGATTTATTCATTCAACAACATACACATATATTAAAACATCACACTGTATTCCAC AAATATATATAATTTTTGTCAATTAAAAAATAATTTTTAAAAATGAGAAACAAAAAAGCT GACATTTTCAGATTAAAAAAATTATACAGAAGAATTAATTCATTAAAGTAAAAACAAATG TGGGAAAATGGTTTTTAAATATAATTTAAACCAAATTTAAAATAAGCATATAAAGACTAT GGACAAAACAAGAAATCCAAATAAAAAATAAACATATGAAGAATATTCAAACTCACTTTT TATCAAAGAAATGTAAATTTTAAAATATAGCATTGCTATTGTGTTTTCATAAATAATAAT ATATCATGGATGAGCCTGTGAGGAAACAGACACTCATACTCTGCAAAGCAATGACTAAGA TAATTATGTCAGATCATGAATTACGTTAATTAGCTTGATGGTGGTCACTGTTTCACGATA AATATACATATGTATCAAAACATCACATTACACACCATAAAGATATATAACTTGTTATCA AAAAGAAATATAGCAGTTAAAATTTAAAATTTTTAAAAAACGTCTTTTTGAGGTTCGTAC CTCACTTAAGTCACACTGTTCAAAATATTCATGCACTCATTTCTCTCATTCATGTGTTAA TGTACAGGGTACGGGCCACTATAAATTCCTTCAGCAACTGGAAAGGAAACTTTATGTACT GAGTGCTCAGAGTTGTATTAACTTTTTTTTTTTTTTGAGCAGCAGCAAGATTTATTGTGA AGAGTGAAAGAACAAAGCTTCCACAGTGTGGAAGGGGACCCGAGCGGTTTGCCCAGTTGT ATTAACTTCTAATTCAACACTTTAAGATTCTTAGCATTATTGCAGACAACATCAGCTTCA CAAGTGTGTGTCCTGTGCAGTTGAACAAGATCCCACACTTAAAAGGATCCTACACTTTTT TTAATGCTCTGCTGTTTCTGCCTTGAAATTCTTAACAATTTTTTTAACCAAAGTCCTCAC AAATTCAGTTTACATTAGCCCTGCAATCATGTAGACATCCTGATTCCAGACAATGTGTCT GGAGGCAGGGTTTACAGGACTTCAAGAACCTTACCTTCTCAACTTTCATCTGCATCTTTA CTCCCAACTATATATGAAGATGATGAAGATAGATATGGATGGTGCTTCTACCATACCCTC TTCCTCTGCCAAACTTCCTTGATCTAGGATAAGGTCAGTAAACTTCTTCCGTAAAAGGCC AAAAGTAAATATTATAGGCTCTACAGGCCCTAGAGTGTCTGTCATAACTACTCAACTCTT ATTGTAGCATAAAAACTGTCAACAGACAATACAGAAACAAATGAGTGTGACTGGGTTCCA GTGAAACTTTATTTACAAAAGATTTGTCCCATGAGTCAAATTTACCACCTCCAGATCTAG AGAAACAGTTTTGAGCCCTTTTATTTTGCTCAACAGTTAAGCATGGCTCCATGTCCCTTA TATTTAGTCAGAACTCGGTATGTTTTAAGGAAAGAATGGTTACACGAAGACATACATTCA TTCATTTATACAACACATTTTCAGTGTTGAATGATAAATTTTGGAATAGTTAACAGATGA TAAAAGTGTTGTTTTCAGTCATCCCTATCCAATGAAGTAAAAAAAAAAGTGTTGAATGGG AAGAAATCAAGAATAGTTATACGAATATCACCATTGCATTAAAGCTCTCTTCCTTGTTTC TAAAAGAATATCTTGACACACATTAAGCTCACTGACCCCCACACCATGAATGAGGGCATC TTCAACAATGGTGGATGACGTCTTAGTTTCCCTCAACTCAGTTAATCTAAGTAAGCTCAT GGTATCACTTTCCTGTCCTAGAGGGAACATATTTCCTGCATTTTTCTTTTTTTCCTTACT TTCCATCACCAAGTAACTCTTCTGATATTTTTTCTCTTGAGAAAATTAATATGACTCATA GATCTGGTTCCCAAGAGAAATCAATGGAGGCCTGGTTACAAGGATCTAAGAAGCATCAAT GGGTCACTAACATCTAGTGGTACTAATTAACTCTGTTAATCATTGGGAAGAAAATGTATA TATACTTTTGTCTTGGAGCTGATTCTACTAGAAAGCAGAAATCAAAATGATCAGTTTCCC AGTGTCACTACTGCACACCCTGGAACAGAACAGGTAGGTCAGAAAAACGCTCCCAAAGTT TAGCAATGTCAAGGCAATCTCTCTCTTCTTACATTTCCCTTCAACCTTCTATCTCCTCCA CTTTTCTGTTTTCCTCCTATCTCCAATTATTTCAATCCTCAGAGCATTATTCTTACAATC TTAATCACTAAATTATATTACACCCGTTAAAGGAGAGATTTCTAAATGCATTGACATTTG TACTGTCTCTCTTTGGAGAATTAGTATTATAAGGATCTGTTATCTCTTGTCACCTTCCTT ATGTCATATGATATGTCACATTTCCCACTGCGGAGACCAAACATGTTCACATCGTGTGCG TTCCATTTTCCTAATGGAAAGTGGGGGGAAGTGATTTTCTGTCCTCATATAGAGAATGCT GGGGCCATTCCCTCTGTATGCCATATTTGATAAAGCATTTGATAATCTTAGTCAATGCCT GGGCCAAGAATTAAAGGGGTAATTATCAGAATGAAAATGGTTTAATGAAACTGTGTCTAT CAGTTCTGAAAAGGGCCTCTATCACAATGAACTAAGGTAGTTATGAATAGAGCTAAAACT TAGGCAACACCATCCTGGACATAGGAACGGGCAAAGATTTCATGACAAAGACACGGAAAC CAATCACAACAAAAGCAAAAATTGAGAAGTGGAATCTAATAAAACAATAGCTTCTGCACA GCAAAAGAAGCTACCAACAAAGTAAACAGACAACCTACAGAATGGGAGAAAATATTTGCC AACTGTAAGTCTGACAAAAATCTAATATCTGGCAGCTATAAGGAACTTAAATTTACAAGA CAAAAACAACCCCATTAAAAAGTGGGCAAAGAACATGAATAGACACTCTCAAAAGAAGAT ATACATATGGTTAACAAGCATATGAAAAAAAAGCTCAATATACTGAGCATTAGAGAAATG CAAATCAAAACCATATTGAGATATCATCTCATACCAGGCAGAATGGCTATTATTAAAAAG TCAAAAATAACAGATATCGGTGAGGTTACAGAGAAAAGGGAACACTTATACACTGTTGGT GGGACTGTAAATTATTTCAACCATTGTGGAAAGCAGTATGGGATGGCGATTCCTCAAAAA GCCAAAAACAGAACTATCATTCAACCCAGCAATTCCATTACTGGGTATATACCCAGAAGA ATATAAATCGTTCTACCATAAAGACGCATGCATGAGAATGTTCATTGCAGCACTACTCAC AATAGCAGAGACATGGAATCAACTTAAATGCCCATCAGTAACAGACTGGATAAAGAAAGT GTGGTACAGATACACCGTGGATTACTATGCAGCCATAAAAAAGAACAAGATCATGTCTTT GACAGGAACATGGATGGAGCTGGAGGCTACTATCCTTAGCAAGCTAAGGCAGGAACAGAA ATCCAAATACCGCATGTTCTCACTTATGAGCGTGAGATAAATGATGAGAACTTGTAAACA CAAAGAAGGAAACAACAGGCAGTGGGGTCTACTTGAGGACGACGGGAAGAGGGAGAGGAG CAGAAAAGATAACTACTGACTACCGGGCGCTACCTGGGGGATGAAACAATCTGTACAACG AACCCCCAGGACATGAGTTTACCTATGTAACAAACCTTCACGTGTACCCCCGAACCTAAA ATAAAAGTCAAAAAGAAAAAGAAAAAAAGAAAAATCCATGCATATGATACATCAGTTAAC AAGGCACTGGTGAAATTAATTTTAAGTATTATTGTCTCTTTGTGTTTTTGGTCTCAGAAA AGTTACGATTTCCCTTAGTTCCTTAGGGCAGAGAGAATCTTCAATCACTGAAGTCAGGAG ACACACATTCTATCTGATTTTCTACATTATCTGTTTGAAAAGGTTACCCACTTATTAGTG TTAAAGCCAAGATATCCAGCAAGGATAGCAACCAACTCTTAAGGTACTCTCCCTTAGGAG GATTCCTGATTCTTTAATGTTTTCTAAAAAAGCAAAACAAACAAACAAACAAAACAAAAC ACTAAATGTTTTCTCTTTCAACTTATTTGAATACACTCTTTTCTCACTGCTCTGAGCATG AATTCAATATTTCAGGGCAAACTAACTGAATGTTAGAACCAACTCCTGATAAGTCTTGAA CAAAAGATAGGATCCTCTAT chr2L 10 15 None 255 + 10 15 0,0,0 1 5, 0, chr2L 70 75 None 255 - 70 75 0,0,0 1 5, 0, chr2L 70 75 None 255 - 70 75 0,0,0 1 5, 0, chr2L 140 145 None 255 - 140 145 0,0,0 1 5, 0, chr2L 140 145 None 255 - 140 145 0,0,0 1 5, 0, chr2L 150 155 None 255 - 150 155 0,0,0 1 5, 0, chr2L 210 215 None 255 + 210 215 0,0,0 1 5, 0, chr2L 70 75 None 255 + 70 75 0,0,0 1 5, 0, chr2L 70 75 None 255 + 70 75 0,0,0 1 5, 0, chr2L 140 145 None 255 + 140 145 0,0,0 1 5, 0, chr2L 140 145 None 255 + 140 145 0,0,0 1 5, 0, chr2L 160 165 None 255 + 160 165 0,0,0 1 5, 0, chr7 32599076 33069221 NAq intron chr7 33059336 33060883 NT5C3A intron chr1 100 200 chr1 150 250 chr2 100 200 chr1 200 300 chr1 46626685 46645317 1527 4.01 . 46626685 46645317 128,0,128 102 1,104,89,167,139,135,140,141,107,94,153,178,132,162,163,147,131,133,187,146,201,242,98,156,171,167,163,153,143,143,156,143,155,119,142,139,157,94,201,163,163,160,157,154,129,147,163,158,151,170,133,144,146,151,168,132,319,205,149,132,161,153,146,140,166,130,153,151,100,179,158,156,189,178,141,130,136,168,146,176,157,124,131,166,175,152,201,184,111,123,212,148,169,340,166,260,141,154,156,139,159,1 0,99,223,403,601,794,938,1124,1324,1527,1633,1787,2021,2176,2347,2522,2752,2931,3079,3276,3434,3636,3879,3987,4146,4352,4550,4740,4915,5069,5235,5441,5600,5780,5919,6097,6264,6490,6599,6805,6969,7177,7384,7559,7766,7929,8077,8275,8469,8640,8859,9012,9163,9341,9544,9713,9902,10222,10447,10600,10788,10969,11149,11314,11479,11699,11882,12065,12297,12431,12625,12793,12955,13145,13344,13517,13681,13822,14018,14205,14382,14580,14733,14910,15094,15272,15462,15667,15852,16022,16173,16406,16593,16827,17168,17335,17690,17834,18082,18264,18442,18631 ##fileformat=VCFv4.1 chr1 1 a G 70.90 . TOOL=LUMPY;SVTYPE=DEL;SVLEN=-389,-4611;END=253195;STR=+-:4;IMPRECISE;CIPOS=-2,137;CIEND=0,0;EVENT=791255;SUP=4;PESUP=4;SRSUP=0;EV=PE;PRIN;CSQ=intergenic_variant|||||||||| chr1 4 a G 70.90 . TOOL=LUMPY;SVTYPE=DEL;SVLEN=-4611;END=253195;STR=+-:4;IMPRECISE;CIPOS=-2,137;CIEND=0,0;EVENT=791255;SUP=4;PESUP=4;SRSUP=0;EV=PE;PRIN;CSQ=intergenic_variant|||||||||| asdvs akreg adjhae ckjvsdfjklb l,df ##fileformat=VCFv4.1 19 256900 791255 G T 70.90 . TOOL=LUMPY;SVTYPE=DEL;SVLEN=-389,-4611;END=253195;STR=+-:4;IMPRECISE;CIPOS=-2,137;CIEND=0,0;EVENT=791255;SUP=4;PESUP=4;SRSUP=0;EV=PE;PRIN;CSQ=intergenic_variant|||||||||| 19 260800 791256 C 33.71 . TOOL=LUMPY;SVTYPE=DEL;SVLEN=680;END=261045;STR=+-:4;IMPRECISE;CIPOS=-1,257;CIEND=0,0;EVENT=791256;SUP=4;PESUP=4;SRSUP=0;EV=PE;PRIN;CSQ=upstream_gene_variant|||ENSG00000271846|CTD-3113P16.9|ENST00000607399|||||processed_pseudogene 19 265500 791257 A 20.25 . TOOL=LUMPY;SVTYPE=DEL;SVLEN=-558;END=265692;STR=+-:4;IMPRECISE;CIPOS=-1,196;CIEND=0,0;EVENT=791257;SUP=4;PESUP=4;SRSUP=0;EV=PE;PRIN;CSQ=intergenic_variant|||||||||| 19 266003 791258 A C 22.15 . TOOL=LUMPY;SVTYPE=DEL;SVLEN=-401;END=266387;STR=+-:6;IMPRECISE;CIPOS=-2,87;CIEND=0,0;EVENT=791258;SUP=6;PESUP=6;SRSUP=0;EV=PE;PRIN;CSQ=intergenic_variant|||||||||| chr1 8 12 b1 1 + chr2 8 12 b2 1 + @HD VN:1.0 GO:none SO:coordinate @SQ SN:chr1 LN:249250621 one_blocks 16 chr1 1 40 30M * 0 0 GAAGGCCACCGCCGCGGTTATTTTCCTTCA CCCDDB?=FJIIJIGFJIJHIJJJJJJJJI MD:Z:50 chr1 10 20 345.7 why? 11 foo bar biz 11 bang bop 99 BCX[hU5J[o R[HZ4UI mI6l̍zA(HEV BK|}oX|/[,_Z̜m9oix@ÛJ}:i)>9;1]u=uS熇6mƦC u۾9xY+Vf<35\[Wm#S92;?1R:4Q*= $QƭI9Rrg Qy:Fa'*L 8VFRceܜgS)klsR 3),n2-Rh8δ6Zhb+<8Sɀ/!$ š"j(_TA˪\PB6H,dB:w!~RfIuL:)cQͽGJ`o@P47zG~v2\bYHq`YŲ/ e6A䝂iee٧!Uȁ d aCuKĭAoA/-qL yLup47nEoTi5dgJG'+[1fKk{lo m%4 A^UUٙMQpx58\eߜ0DRVg ts L.9`dҳm빆8B%/;k;q%\ ŭBQ 'tۦ>UM[ +z' eW 87^;Cw[RONje%ZF`sE/QV-{iqEGa ~XQlLC7+B׆]bݗ W ~ֽ~!(xV4^ 7py֦wͰkniƦM#YMu#~_,5Η`Bt>s}6,SmX<QME+_iR\*GlIGppa`#?#zL[5*pBZ5{V#j -#jCffkgj?m{5eD`9%YD-`KD-) ;4ْVxoDm$ǧ575O^Z}Z j k "j V "jENSZ?G5CZ7Qln oGѸwNvp׷Ґ7Sp UiS!BCset -e; BT=${BT-../../bin/bedtools} htsutil=${htsutil-../htsutil} FAILURES=0; check() { if diff $1 $2; then echo ok else FAILURES=$(expr $FAILURES + 1); echo fail fi } ########################################################### # Test a basic self intersection ############################################################ echo -e " intersect.t01...\c" echo \ "chr1 10 20 a1 1 + chr1 100 200 a2 2 -" > exp $BT intersect -a a.bed -b a.bed > obs check obs exp rm obs exp ########################################################### # Test a basic self intersection with -v ############################################################ echo -e " intersect.t02...\c" # expectation is empty set touch exp $BT intersect -a a.bed -b a.bed -v > obs check obs exp rm obs exp ########################################################### # Test -c ############################################################ echo -e " intersect.t03...\c" echo \ "chr1 10 20 a1 1 + 0 chr1 100 200 a2 2 - 2" > exp $BT intersect -a a.bed -b b.bed -c > obs check obs exp rm obs exp ########################################################### # Test -c with -s ############################################################ echo -e " intersect.t04...\c" echo \ "chr1 10 20 a1 1 + 0 chr1 100 200 a2 2 - 1" > exp $BT intersect -a a.bed -b b.bed -c -s > obs check obs exp rm obs exp ########################################################### # Test -c with -s and -f ############################################################ echo -e " intersect.t05...\c" echo \ "chr1 10 20 a1 1 + 0 chr1 100 200 a2 2 - 0" > exp $BT intersect -a a.bed -b b.bed -c -s -f 0.1 > obs check obs exp rm obs exp ########################################################### # Test plain a and b intersect ############################################################ echo -e " intersect.t06...\c" echo \ "chr1 100 101 a2 2 - chr1 100 110 a2 2 -" > exp $BT intersect -a a.bed -b b.bed > obs check obs exp rm obs exp ########################################################### # Test with -wa ############################################################ echo -e " intersect.t07...\c" echo \ "chr1 100 200 a2 2 - chr1 100 200 a2 2 -" > exp $BT intersect -a a.bed -b b.bed -wa > obs check obs exp rm obs exp ########################################################### # Test with -wa and -wb ############################################################ echo -e " intersect.t08...\c" echo \ "chr1 100 200 a2 2 - chr1 90 101 b2 2 - chr1 100 200 a2 2 - chr1 100 110 b3 3 +" > exp $BT intersect -a a.bed -b b.bed -wa -wb > obs check obs exp rm obs exp ########################################################### # Test with -wo (write overlap) ############################################################ echo -e " intersect.t09...\c" echo \ "chr1 100 200 a2 2 - chr1 90 101 b2 2 - 1 chr1 100 200 a2 2 - chr1 100 110 b3 3 + 10" > exp $BT intersect -a a.bed -b b.bed -wo > obs check obs exp rm obs exp ########################################################### # Test with -wao (write all overlap) ############################################################ echo -e " intersect.t10...\c" echo \ "chr1 10 20 a1 1 + . -1 -1 . -1 . 0 chr1 100 200 a2 2 - chr1 90 101 b2 2 - 1 chr1 100 200 a2 2 - chr1 100 110 b3 3 + 10" > exp $BT intersect -a a.bed -b b.bed -wao > obs check obs exp rm obs exp ########################################################### # Test with -wo (write overlap) with -s ############################################################ echo -e " intersect.t11...\c" echo \ "chr1 100 200 a2 2 - chr1 90 101 b2 2 - 1" > exp $BT intersect -a a.bed -b b.bed -wo -s > obs check obs exp rm obs exp ########################################################### # Test with -wao (write all overlap) with -s ############################################################ echo -e " intersect.t12...\c" echo \ "chr1 10 20 a1 1 + . -1 -1 . -1 . 0 chr1 100 200 a2 2 - chr1 90 101 b2 2 - 1" > exp $BT intersect -a a.bed -b b.bed -wao -s > obs check obs exp rm obs exp ########################################################### # Test A as - ############################################################ echo -e " intersect.t13...\c" echo \ "chr1 100 101 a2 2 - chr1 100 110 a2 2 -" > exp cat a.bed | $BT intersect -a - -b b.bed > obs check obs exp rm obs exp ########################################################### # Test A as stdin ############################################################ echo -e " intersect.t14...\c" echo \ "chr1 100 101 a2 2 - chr1 100 110 a2 2 -" > exp cat a.bed | $BT intersect -a stdin -b b.bed > obs check obs exp rm obs exp ########################################################### # Test B as - ############################################################ echo -e " intersect.t15...\c" echo \ "chr1 100 101 a2 2 - chr1 100 110 a2 2 -" > exp cat b.bed | $BT intersect -a a.bed -b - > obs check obs exp rm obs exp ########################################################### # Test A as stdin ############################################################ echo -e " intersect.t16...\c" echo \ "chr1 100 101 a2 2 - chr1 100 110 a2 2 -" > exp cat b.bed | $BT intersect -a a.bed -b stdin > obs check obs exp rm obs exp ########################################################### ########################################################### # -split # ########################################################### ########################################################### $htsutil samtobam one_block.sam one_block.bam $htsutil samtobam two_blocks.sam two_blocks.bam $htsutil samtobam three_blocks.sam three_blocks.bam $htsutil samtobam split.issue750.sam split.issue750.bam ################################################################## # Test three blocks matches BED without -split ################################################################## echo -e " intersect.t17...\c" echo \ "three_blocks 16 chr1 1 40 10M10N10M10N10M * 0 0 GAAGGCCACCGCCGCGGTTATTTTCCTTCA CCCDDB?=FJIIJIGFJIJHIJJJJJJJJI MD:Z:50" > exp $BT intersect -abam three_blocks.bam -b three_blocks_nomatch.bed | $htsutil viewbamrecords > obs check obs exp rm obs exp ################################################################## # Test three blocks does not match BED with -split ################################################################## echo -e " intersect.t18...\c" touch exp $BT intersect -abam three_blocks.bam -b three_blocks_nomatch.bed -split | $htsutil viewbamrecords > obs check obs exp rm obs exp ################################################################## # Test three blocks matches BED with -split ################################################################## echo -e " intersect.t19...\c" echo \ "three_blocks 16 chr1 1 40 10M10N10M10N10M * 0 0 GAAGGCCACCGCCGCGGTTATTTTCCTTCA CCCDDB?=FJIIJIGFJIJHIJJJJJJJJI MD:Z:50" > exp $BT intersect -abam three_blocks.bam -b three_blocks_match.bed -split | $htsutil viewbamrecords > obs check obs exp rm obs exp ################################################################## # Test three blocks does not match BED with -split and -s # BAM os -, BED is + ################################################################## echo -e " intersect.t20...\c" touch exp $BT intersect -abam three_blocks.bam -b three_blocks_match.bed -split -s | $htsutil viewbamrecords > obs check obs exp rm obs exp ################################################################## # Test three blocks match BED that overlap 1bp with -split ################################################################## echo -e " intersect.t21...\c" echo \ "three_blocks 16 chr1 1 40 10M10N10M10N10M * 0 0 GAAGGCCACCGCCGCGGTTATTTTCCTTCA CCCDDB?=FJIIJIGFJIJHIJJJJJJJJI MD:Z:50" > exp $BT intersect -abam three_blocks.bam -b three_blocks_match_1bp.bed -split | $htsutil viewbamrecords > obs check obs exp rm obs exp ################################################################################ # Test three blocks does not match BED that overlap 1bp with -split and -f 0.1 ################################################################################ echo -e " intersect.t22...\c" touch exp $BT intersect -abam three_blocks.bam -b three_blocks_match_1bp.bed -split -f 0.1 | $htsutil viewbamrecords > obs check obs exp rm obs exp ########################################################### # Test three blocks with -split -wo only shows 5 overlap # bases, not ten. ############################################################ echo -e " intersect.t22.a...\c" echo "chr1 0 50 three_blocks_match 0 + 0 0 0 3 10,10,10, 0,20,40, chr1 5 15 5" > exp $BT intersect -a three_blocks_match.bed -b d.bed -split -wo > obs check obs exp rm obs exp ########################################################### # Same test but for BAM file ############################################################ echo -e " intersect.t22.b...\c" echo "chr1 0 50 three_blocks_match 255 + 0 50 0,0,0 3 10,10,10, 0,20,40, chr1 5 15 5" > exp $BT intersect -a three_blocks_match.bam -b d.bed -split -wo -bed > obs check obs exp rm obs exp ########################################################### # Test three blocks with -split -wo, and DB record also has # blocks that somewhat intersect ############################################################ echo -e " intersect.t22.c...\c" echo "chr1 0 50 three_blocks_match 0 + 0 0 0 3 10,10,10, 0,20,40, chr1 0 45 three_blocks_match 0 + 0 0 0 2 5,10, 25,35, 10" > exp $BT intersect -a three_blocks_match.bed -b two_blocks_partial.bed -split -wo > obs check obs exp rm obs exp ########################################################### # Same test but for BAM file ############################################################ echo -e " intersect.t22.d...\c" echo "chr1 0 50 three_blocks_match 255 + 0 50 0,0,0 3 10,10,10, 0,20,40, chr1 0 45 three_blocks_match 0 + 0 0 0 2 5,10, 25,35, 10" > exp $BT intersect -a three_blocks_match.bam -b two_blocks_partial.bed -split -wo -bed > obs check obs exp rm obs exp ########################################################### # Test three blocks with -split -wo, and DB record also has # blocks that do not intersect ############################################################ echo -e " intersect.t22.e...\c" touch exp $BT intersect -a three_blocks_match.bed -b three_blocks_nomatch.bed -split -wo > obs check obs exp rm obs exp ########################################################### # Same test but for BAM file ############################################################ echo -e " intersect.t22.f...\c" touch exp $BT intersect -a three_blocks_match.bam -b three_blocks_nomatch.bed -split -wo -bed > obs check obs exp rm obs exp ########################################################### # Added split test from bug150. See that overlap bases # with -split are correctly affected by overlap fraction ############################################################ echo -e " intersect.t22.g...\c" echo \ "chr2 1000 16385 A 0 - 0 0 0 2 1,1, 0,15384, chr2 1000 16385 A 0 - 0 0 0 2 1,1, 0,15384, 2" > exp $BT intersect -a bug150_a.bed -b bug150_b.bed -s -split -wo > obs check exp obs rm exp obs ########################################################### # Test that -f is based on the cumulative fraction of the # split overlaps for the A interval, not based on _each_ # alignment. See issue #750: # https://github.com/arq5x/bedtools2/issues/750 ############################################################ echo -e " intersect.t22.h...\c" echo \ "chr1 0 30 one_block_one_exon_30bp 40 - 0 30 0,0,0 1 30, 0, chr1 0 100 exon1 1 + 30 chr1 80 110 one_block_one_exon_20bp 40 - 80 110 0,0,0 1 30, 0, chr1 0 100 exon1 1 + 20 chr1 90 220 two_blocks_two_exons 40 - 90 220 0,0,0 2 10,20, 0,110, chr1 0 100 exon1 1 + 10 chr1 90 220 two_blocks_two_exons 40 - 90 220 0,0,0 2 10,20, 0,110, chr1 200 300 exon2 2 - 20" > exp $BT intersect -a split.issue750.bam -b exons.issue750.bed -f 0.5 -bed -split -wo > obs check obs exp rm obs exp ########################################################### # Test that -f is based on the cumulative fraction of the # split overlaps for the A interval, not based on _each_ # alignment. See issue #750: # https://github.com/arq5x/bedtools2/issues/750 # With -u ############################################################ echo -e " intersect.t22.i...\c" echo \ "chr1 0 30 one_block_one_exon_30bp 40 - 0 30 0,0,0 1 30, 0, chr1 80 110 one_block_one_exon_20bp 40 - 80 110 0,0,0 1 30, 0, chr1 90 220 two_blocks_two_exons 40 - 90 220 0,0,0 2 10,20, 0,110," > exp $BT intersect -a split.issue750.bam -b exons.issue750.bed -f 0.5 -bed -split -u > obs check obs exp rm obs exp ########################################################### # Test that -f is based on the cumulative fraction of the # split overlaps for the A interval, not based on _each_ # alignment. See issue #750: # https://github.com/arq5x/bedtools2/issues/750 # Increase fraction of overlap ############################################################ echo -e " intersect.t22.j...\c" echo \ "chr1 0 30 one_block_one_exon_30bp 40 - 0 30 0,0,0 1 30, 0, chr1 0 100 exon1 1 + 30 chr1 90 220 two_blocks_two_exons 40 - 90 220 0,0,0 2 10,20, 0,110, chr1 0 100 exon1 1 + 10 chr1 90 220 two_blocks_two_exons 40 - 90 220 0,0,0 2 10,20, 0,110, chr1 200 300 exon2 2 - 20" > exp $BT intersect -a split.issue750.bam -b exons.issue750.bed -f 0.7 -bed -split -wo > obs check obs exp rm obs exp ########################################################### # Test that -f is based on the cumulative fraction of the # split overlaps for the A interval, not based on _each_ # alignment. See issue #750: # https://github.com/arq5x/bedtools2/issues/750 # Increase fraction of overlap ############################################################ echo -e " intersect.t22.j...\c" echo \ "chr1 0 30 one_block_one_exon_30bp 40 - 0 30 0,0,0 1 30, 0, chr1 0 100 exon1 1 + 30 chr1 80 110 one_block_one_exon_20bp 40 - 80 110 0,0,0 1 30, 0, . -1 -1 . -1 . 0 chr1 90 220 two_blocks_two_exons 40 - 90 220 0,0,0 2 10,20, 0,110, chr1 0 100 exon1 1 + 10 chr1 90 220 two_blocks_two_exons 40 - 90 220 0,0,0 2 10,20, 0,110, chr1 200 300 exon2 2 - 20" > exp $BT intersect -a split.issue750.bam -b exons.issue750.bed -f 0.7 -bed -split -wao > obs check obs exp rm obs exp ########################################################### # Test that -f is based on the cumulative fraction of the # split overlaps for the A interval, not based on _each_ # alignment. See issue #750: # https://github.com/arq5x/bedtools2/issues/750 # Increase fraction of overlap ############################################################ echo -e " intersect.t22.k...\c" echo \ "chr1 0 30 one_block_one_exon_30bp 40 - 0 30 0,0,0 1 30, 0, chr1 90 220 two_blocks_two_exons 40 - 90 220 0,0,0 2 10,20, 0,110," > exp $BT intersect -a split.issue750.bam -b exons.issue750.bed -f 0.7 -bed -split -u > obs check obs exp rm obs exp ########################################################### # Test that -f is based on the cumulative fraction of the # split overlaps for the A interval, not based on _each_ # alignment. See issue #750: # https://github.com/arq5x/bedtools2/issues/750 # With -r ############################################################ echo -e " intersect.t22.l...\c" touch exp $BT intersect -a split.issue750.bam -b exons.issue750.bed -f 0.5 -bed -split -wo -r > obs check obs exp rm obs exp ########################################################### # Test that -f is based on the cumulative fraction of the # split overlaps for the A interval, not based on _each_ # alignment. See issue #750: # https://github.com/arq5x/bedtools2/issues/750 # With -r, lowering -f ############################################################ echo -e " intersect.t22.m...\c" echo \ "chr1 0 30 one_block_one_exon_30bp 40 - 0 30 0,0,0 1 30, 0, chr1 0 100 exon1 1 + 30 chr1 80 110 one_block_one_exon_20bp 40 - 80 110 0,0,0 1 30, 0, chr1 0 100 exon1 1 + 20 chr1 90 220 two_blocks_two_exons 40 - 90 220 0,0,0 2 10,20, 0,110, chr1 0 100 exon1 1 + 10 chr1 90 220 two_blocks_two_exons 40 - 90 220 0,0,0 2 10,20, 0,110, chr1 200 300 exon2 2 - 20" > exp $BT intersect -a split.issue750.bam -b exons.issue750.bed -f 0.1 -bed -split -r -wo > obs check obs exp rm obs exp ########################################################### # Test that -f is based on the cumulative fraction of the # split overlaps for the A interval, not based on _each_ # alignment. See issue #750: # https://github.com/arq5x/bedtools2/issues/750 # With -F ############################################################ echo -e " intersect.t22.n...\c" touch exp $BT intersect -a split.issue750.bam -b exons.issue750.bed -F 0.5 -bed -split -wo > obs check obs exp rm obs exp ########################################################### # Test that -f is based on the cumulative fraction of the # split overlaps for the A interval, not based on _each_ # alignment. See issue #750: # https://github.com/arq5x/bedtools2/issues/750 # With -F, lowering ############################################################ echo -e " intersect.t22.o...\c" touch exp $BT intersect -a split.issue750.bam -b exons.issue750.bed -F 0.31 -bed -split -wo > obs check obs exp rm obs exp ########################################################### # Test that -f is based on the cumulative fraction of the # split overlaps for the A interval, not based on _each_ # alignment. See issue #750: # https://github.com/arq5x/bedtools2/issues/750 # With -F, lowering ############################################################ echo -e " intersect.t22.p...\c" echo \ "chr1 0 30 one_block_one_exon_30bp 40 - 0 30 0,0,0 1 30, 0, chr1 0 100 exon1 1 + 30" > exp $BT intersect -a split.issue750.bam -b exons.issue750.bed -F 0.30 -bed -split -wo > obs check obs exp rm obs exp ########################################################### # Test that -f is based on the cumulative fraction of the # split overlaps for the A interval, not based on _each_ # alignment. See issue #750: # https://github.com/arq5x/bedtools2/issues/750 # With -F, lowering ############################################################ echo -e " intersect.t22.q...\c" echo \ "chr1 0 30 one_block_one_exon_30bp 40 - 0 30 0,0,0 1 30, 0, chr1 0 100 exon1 1 + 30 chr1 80 110 one_block_one_exon_20bp 40 - 80 110 0,0,0 1 30, 0, chr1 0 100 exon1 1 + 20" > exp $BT intersect -a split.issue750.bam -b exons.issue750.bed -F 0.20 -bed -split -wo > obs check obs exp rm obs exp ########################################################### # Test that -f is based on the cumulative fraction of the # split overlaps for the A interval, not based on _each_ # alignment. See issue #750: # https://github.com/arq5x/bedtools2/issues/750 # With -F, lowering ############################################################ echo -e " intersect.t22.r...\c" echo \ "chr1 0 30 one_block_one_exon_30bp 40 - 0 30 0,0,0 1 30, 0, chr1 0 100 exon1 1 + 30 chr1 80 110 one_block_one_exon_20bp 40 - 80 110 0,0,0 1 30, 0, chr1 0 100 exon1 1 + 20 chr1 90 220 two_blocks_two_exons 40 - 90 220 0,0,0 2 10,20, 0,110, chr1 0 100 exon1 1 + 10 chr1 90 220 two_blocks_two_exons 40 - 90 220 0,0,0 2 10,20, 0,110, chr1 200 300 exon2 2 - 20" > exp $BT intersect -a split.issue750.bam -b exons.issue750.bed -F 0.10 -bed -split -wo > obs check obs exp rm obs exp ########################################################### # Test that -f is based on the cumulative fraction of the # split overlaps for the A interval, not based on _each_ # alignment. See issue #750: # https://github.com/arq5x/bedtools2/issues/750 ############################################################ echo -e " intersect.t22.s...\c" echo \ "chr1 90 220 two_blocks_two_exons 40 - 90 220 0,0,0 2 10,20, 0,110, chr1 200 300 exon2 2 - 20" > exp $BT intersect -a split.issue750.bam -b exons.issue750.bed -f 0.5 -bed -split -wo -s > obs check obs exp rm obs exp ########################################################### # Test that -f is based on the cumulative fraction of the # split overlaps for the A interval, not based on _each_ # alignment. See issue #750: # https://github.com/arq5x/bedtools2/issues/750 ############################################################ echo -e " intersect.t22.t...\c" echo \ "chr1 0 30 one_block_one_exon_30bp 40 - 0 30 0,0,0 1 30, 0, chr1 0 100 exon1 1 + 30 chr1 80 110 one_block_one_exon_20bp 40 - 80 110 0,0,0 1 30, 0, chr1 0 100 exon1 1 + 20" > exp $BT intersect -a split.issue750.bam -b exons.issue750.bed -f 0.5 -bed -split -wo -S > obs check obs exp rm obs exp ########################################################### # Test that -f is based on the cumulative fraction of the # split overlaps for the A interval, not based on _each_ # alignment. See issue #773: # https://github.com/arq5x/bedtools2/issues/773 ############################################################ echo -e " intersect.t22.u...\c" echo \ "X 10 30 A2 1 + 0 30 255,0,0 1 20 0 X 0 20 B1 0 + 10 X 10 30 A2 1 + 0 30 255,0,0 1 20 0 X 0 20 B2 0 + 10" > exp $BT intersect -a issue_773_b.bed -b issue_773_y.bed -f 0.5 -split -wo > obs check obs exp rm obs exp ########################################################### # Test that -f is based on the cumulative fraction of the # split overlaps for the A interval, not based on _each_ # alignment. See issue #773: # https://github.com/arq5x/bedtools2/issues/773 ############################################################ echo -e " intersect.t22.v...\c" touch exp $BT intersect -a issue_773_b.bed -b issue_773_y.bed -f 0.6 -split -wo > obs check obs exp rm obs exp ########################################################### # Test that -f is based on the cumulative fraction of the # split overlaps for the A interval, not based on _each_ # alignment. See issue #773: # https://github.com/arq5x/bedtools2/issues/773 ############################################################ echo -e " intersect.t22.w...\c" echo \ "X 10 30 A2 1 + 0 30 255,0,0 1 20 0 . -1 -1 . -1 . 0" > exp $BT intersect -a issue_773_b.bed -b issue_773_y.bed -f 0.6 -split -wao > obs check obs exp rm obs exp ################################################################## # Test that only the mapped read is is found as an intersection ################################################################## echo -e " intersect.t23...\c" echo \ "mapped 16 chr1 1 40 30M * 0 0 GAAGGCCACCGCCGCGGTTATTTTCCTTCA CCCDDB?=FJIIJIGFJIJHIJJJJJJJJI MD:Z:50" > exp $htsutil samtobam mapped_and_unmapped.sam | $BT intersect -abam - -b a.bed | $htsutil viewbamrecords > obs check obs exp rm obs exp ################################################################## # Test that an unmapped read is handled properly with -v ################################################################## echo -e " intersect.t24...\c" echo \ "umapped 4 * 1 40 30M * 0 0 GAAGGCCACCGCCGCGGTTATTTTCCTTCA CCCDDB?=FJIIJIGFJIJHIJJJJJJJJI MD:Z:50" > exp $htsutil samtobam mapped_and_unmapped.sam | $BT intersect -abam - -b a.bed -v | $htsutil viewbamrecords > obs check obs exp rm obs exp ################################################################## # Test -c with BAM input ################################################################## echo -e " intersect.t25...\c" echo \ "chr1 0 30 one_blocks 40 - 0 30 0,0,0 1 30, 0, 1" > exp $BT intersect -abam one_block.bam -b c.bed -c -bed > obs check obs exp rm obs exp ################################################################## # Test -wo with BAM input ################################################################## echo -e " intersect.t26...\c" echo \ "chr1 0 30 one_blocks 40 - 0 30 0,0,0 1 30, 0, chr1 0 100 c1 1 + 30" > exp $BT intersect -abam one_block.bam -b c.bed -wo -bed > obs check obs exp rm obs exp ################################################################## # Test -wao with BAM input ################################################################## echo -e " intersect.t27...\c" echo \ "chr1 0 30 one_blocks 40 - 0 30 0,0,0 1 30, 0, chr1 0 100 c1 1 + 30" > exp $BT intersect -abam one_block.bam -b c.bed -wo -bed > obs check obs exp ################################################################## # Test BED3 with BED3 ################################################################## echo -e " intersect.t28...\c" echo \ "chr1^I10^I20^Ichr1^I10^I20" > exp $BT intersect -a bed3.bed -b bed3.bed -wa -wb | cat -t > obs check obs exp ################################################################## # Test BED4 with BED3 ################################################################## echo -e " intersect.t29...\c" echo \ "chr1^I10^I20^I345.7^Ichr1^I10^I20" > exp $BT intersect -a bed4.bed -b bed3.bed -wa -wb | cat -t > obs check obs exp ################################################################## # Test BED5 with BED3 ################################################################## echo -e " intersect.t30...\c" echo \ "chr1^I10^I20^I345.7^Iwhy?^Ichr1^I10^I20" > exp $BT intersect -a bed5.bed -b bed3.bed -wa -wb | cat -t > obs check obs exp ################################################################## # Test BED6 (without a proper strand) with BED3 ################################################################## echo -e " intersect.t31...\c" echo \ "chr1^I10^I20^I345.7^Iwhy?^I11^Ichr1^I10^I20" > exp $BT intersect -a bed6.bed -b bed3.bed -wa -wb | cat -t > obs check obs exp ################################################################## # Test BED6 (with a strand) with BED3 ################################################################## echo -e " intersect.t32...\c" echo \ "chr1^I10^I20^I345.7^Iwhy?^I-^Ichr1^I10^I20" > exp $BT intersect -a bed6.strand.bed -b bed3.bed -wa -wb | cat -t > obs check obs exp ################################################################## # Test BED PLUS with BED3 ################################################################## echo -e " intersect.t33...\c" echo \ "chr1^I10^I20^I345.7^Iwhy?^I11^Ifoo^Ibar^Ibiz^I11^Ibang^Ibop^I99^Ichr1^I10^I20" > exp $BT intersect -a bedplus.bed -b bed3.bed -wa -wb | cat -t > obs check obs exp ################################################################## # Test for strand matches with BED3 ################################################################## echo -e " intersect.t34...\c" echo \ "chr1^I10^I20^I345.7^Iwhy?^I11^Ichr1^I10^I20^I345.7^Iwhy?^I-" > exp $BT intersect -a bed6.bed -b bed6.strand.bed -wa -wb | cat -t > obs check obs exp ################################################################## # Test for strand matches with BED3 ################################################################## echo -e " intersect.t35...\c" echo \ "chr1^I10^I20^I345.7^Iwhy?^I-^Ichr1^I10^I20^I345.7^Iwhy?^I-" > exp $BT intersect -a bed6.strand.bed -b bed6.strand2.bed -wa -wb -s | cat -t > obs check obs exp ################################################################## # Test for strand matches with BED3 ################################################################## echo -e " intersect.t36...\c" echo \ "chr1^I10^I20^I345.7^Iwhy?^I-^Ichr1^I11^I21^I345.7^Iwhy?^I+" > exp $BT intersect -a bed6.strand.bed -b bed6.strand2.bed -wa -wb -S | cat -t > obs check obs exp rm obs exp ################################################################## # Test that intersect of bed query with BAM DB gives Bed output. ################################################################## echo -e " intersect.t37...\c" echo \ "chr1 10 20 a1 1 + chr1 100 200 a2 2 -" > exp $BT intersect -a a.bed -b a.bam > obs check obs exp rm obs exp ################################################################## # Test that -split works on identical records even if # -f 1 is ued (100% overlap) ################################################################## echo -e " intersect.t38...\c" echo \ "chr1 1 100 A 0 + 1 100 0 2 10,10 0,90 chr1 1 100 B 0 + 1 100 0 2 10,10 0,90 20" > exp $BT intersect -wao -f 1 -split -a splitBug155_a.bed -b splitBug155_b.bed > obs check obs exp rm obs exp ################################################################## # Test that fractional overlap must be greater than 0.0 ################################################################## echo -e " intersect.t39...\c" echo \ "***** ERROR: -f must be in the range (0.0, 1.0]. *****" > exp $BT intersect -a a.bed -b b.bed -f 0.0 2>&1 > /dev/null | cat - | tail -1 > obs check exp obs rm exp obs ################################################################## # Test that fractional overlap must be <= than 1.0 ################################################################## echo -e " intersect.t40...\c" echo \ "***** ERROR: -f must be in the range (0.0, 1.0]. *****" > exp $BT intersect -a a.bed -b b.bed -f 1.00001 2>&1 > /dev/null | cat - | tail -1 > obs check exp obs rm exp obs ################################################################## # bug167_strandSweep.bed ################################################################## echo -e " intersect.t41...\c" echo \ "22" > exp $BT intersect -a bug167_strandSweep.bed -b bug167_strandSweep.bed -sorted -s -wa -wb | wc -l | sed 's/^[ \t]*//' > obs check exp obs rm exp obs ################################################################## # bug167_strandSweep.bed ################################################################## echo -e " intersect.t42...\c" echo \ "20" > exp $BT intersect -a bug167_strandSweep.bed -b bug167_strandSweep.bed -sorted -S -wa -wb | wc -l | sed 's/^[ \t]*//' > obs check exp obs rm exp obs rm one_block.bam two_blocks.bam three_blocks.bam ################################################################## # Bug 187 0 length records ################################################################## echo -e " intersect.t43...\c" echo \ "chr7 33059403 33059403 chr7 33059336 33060883 NT5C3A intron 0 chr7 33059403 33059403 chr7 32599076 33069221 NAq intron 0" > exp $BT intersect -a bug187_a.bed -b bug187_b.bed -wao > obs check exp obs rm exp obs ################################################################## # see that naming conventions are tested with unsorted data. ################################################################## echo -e " intersect.t44...\c" echo \ "***** WARNING: File nonamecheck_a.bed has a record where naming convention (leading zero) is inconsistent with other files: chr1 10 20" > exp $BT intersect -a nonamecheck_a.bed -b nonamecheck_b.bed 2>&1 > /dev/null | cat - | head -2 > obs check exp obs rm exp obs ################################################################## # see that differently named chroms don't work with -sorted ################################################################## echo -e " intersect.t45...\c" echo \ "***** WARNING: File nonamecheck_b.bed has a record where naming convention (leading zero) is inconsistent with other files: chr01 15 25" > exp $BT intersect -a nonamecheck_a.bed -b nonamecheck_b.bed -sorted 2>&1 > /dev/null | cat - | head -2 > obs check exp obs rm exp obs ################################################################## # see that differently named chroms -sorted and -nonamecheck # don't complain with -nonamecheck ################################################################## echo -e " intersect.t46...\c" touch exp $BT intersect -a nonamecheck_a.bed -b nonamecheck_b.bed -sorted -nonamecheck 2>&1 > /dev/null | cat - > obs check exp obs rm exp obs ################################################################## # see that SVLEN in VCF files is treated as zero length # records when the SV type is an insertion ################################################################## echo -e " intersect.t47...\c" echo \ "chr1 1 a G 70.90 chr1 1 a G 70.90 chr1 4 a G 70.90" > exp $BT intersect -a bug223_sv1_a.vcf -b bug223_sv1_b.vcf | cut -f1-6 > obs check exp obs rm exp obs ################################################################## # see that SVLEN in VCF files can handle multiple numbers, # at end of line, followed by NULL. ################################################################## echo -e " intersect.t48...\c" echo \ "chr1 1 a G 70.90 chr1 1 a G 70.90 chr1 4 a G 70.90 chr1 4 a G 70.90" > exp $BT intersect -a bug223_d.vcf -b bug223_d.vcf | cut -f1-6 > obs check exp obs rm exp obs ################################################################## # see that SVLEN in VCF files can handle multiple numbers, # at end of line, followed by a tab ################################################################## echo -e " intersect.t49...\c" echo \ "chr1 1 a G 70.90 chr1 1 a G 70.90 chr1 4 a G 70.90 chr1 4 a G 70.90" > exp $BT intersect -a bug223_e.vcf -b bug223_e.vcf | cut -f1-6 > obs check exp obs rm exp obs ################################################################## # see that SVLEN in VCF files can handle single numbers, # at end of line, followed by null ################################################################## echo -e " intersect.t50...\c" echo \ "chr1 1 a G 70.90 chr1 1 a G 70.90 chr1 4 a G 70.90 chr1 4 a G 70.90" > exp $BT intersect -a bug223_f.vcf -b bug223_f.vcf | cut -f1-6 > obs check exp obs rm exp obs ################################################################## # Bug 44: test that bgzipped vcf file works correctly # with race condition ################################################################## echo -e " intersect.t51...\c" echo \ "MT 2706 . A G 2965 PASS BRF=0.05;FR=1;HP=1;HapScore=1;MGOF=17;MMLQ=30;MQ=62.05;NF=7607;NR=8147;PP=2965;QD=20;SC=AGGCGGGCATAACACAGCAAG;SbPval=0.52;Source=Platypus;TC=15840;TCF=7679;TCR=8161;TR=15754;WE=2749;WS=2693;CSQ=G|ENSG00000198763|ENST00000361453|Transcript|upstream_gene_variant||||||rs2854128|1764|1|MT-ND2|HGNC|7456|protein_coding|YES||ENSP00000355046|NU2M_HUMAN|Q7GXY9_HUMAN&Q5Q3P5_HUMAN&Q14X33_HUMAN&Q14WT3_HUMAN&A6ZH82_HUMAN&A6ZGN8_HUMAN&A6ZGG3_HUMAN|UPI0000000AA2||||||A:0.1656|||||||||||||,G|ENSG00000210151|ENST00000387416|Transcript|downstream_gene_variant||||||rs2854128|4740|-1|MT-TS1|HGNC|7497|Mt_tRNA|YES|||||||||||A:0.1656|||||||||||||,G|ENSG00000210077|ENST00000387342|Transcript|downstream_gene_variant||||||rs2854128|1036|1|MT-TV|HGNC|7500|Mt_tRNA|YES|||||||||||A:0.1656|||||||||||||,G|ENSG00000210144|ENST00000387409|Transcript|downstream_gene_variant||||||rs2854128|3120|-1|MT-TY|HGNC|7502|Mt_tRNA|YES|||||||||||A:0.1656|||||||||||||,G|ENSG00000210117|ENST00000387382|Transcript|upstream_gene_variant||||||rs2854128|2806|1|MT-TW|HGNC|7501|Mt_tRNA|YES|||||||||||A:0.1656|||||||||||||,G|ENSG00000210107|ENST00000387372|Transcript|downstream_gene_variant||||||rs2854128|1623|-1|MT-TQ|HGNC|7495|Mt_tRNA|YES|||||||||||A:0.1656|||||||||||||,G|ENSG00000210140|ENST00000387405|Transcript|downstream_gene_variant||||||rs2854128|3055|-1|MT-TC|HGNC|7477|Mt_tRNA|YES|||||||||||A:0.1656|||||||||||||,G|ENSG00000211459|ENST00000389680|Transcript|downstream_gene_variant||||||rs2854128|1105|1|MT-RNR1|HGNC|7470|Mt_rRNA|YES|||||||||||A:0.1656|||||||||||||,G|ENSG00000210082|ENST00000387347|Transcript|non_coding_transcript_exon_variant&non_coding_transcript_variant|1036|||||rs2854128||1|MT-RNR2|HGNC|7471|Mt_rRNA|YES||||||||1/1|||A:0.1656|||||||||||||,G|ENSG00000210127|ENST00000387392|Transcript|downstream_gene_variant||||||rs2854128|2881|-1|MT-TA|HGNC|7475|Mt_tRNA|YES|||||||||||A:0.1656|||||||||||||,G|ENSG00000198712|ENST00000361739|Transcript|upstream_gene_variant||||||rs2854128|4880|1|MT-CO2|HGNC|7421|protein_coding|YES||ENSP00000354876|COX2_HUMAN|Q7GXZ8_HUMAN&Q4R1L5_HUMAN&Q4R1L3_HUMAN&Q14XT3_HUMAN&K7WVJ5_HUMAN&H9E7W2_HUMAN&H9E7T7_HUMAN&H9E7P8_HUMAN&H9E7F7_HUMAN&E2DTL8_HUMAN&D3WYY9_HUMAN&D2Y6Y2_HUMAN&D2Y6Y1_HUMAN&B2YKU2_HUMAN|UPI0000000AA4||||||A:0.1656|||||||||||||,G|ENSG00000210049|ENST00000387314|Transcript|downstream_gene_variant||||||rs2854128|2059|1|MT-TF|HGNC|7481|Mt_tRNA|YES|||||||||||A:0.1656|||||||||||||,G|ENSG00000198888|ENST00000361390|Transcript|upstream_gene_variant||||||rs2854128|601|1|MT-ND1|HGNC|7455|protein_coding|YES||ENSP00000354687|NU1M_HUMAN|Q85KV6_HUMAN&Q8WCX9_HUMAN&Q5Q757_HUMAN&Q14WI3_HUMAN&G3EBI1_HUMAN&D2Y6X8_HUMAN&D2Y6X6_HUMAN&A6ZHG8_HUMAN|UPI0000000AA1||||||A:0.1656|||||||||||||,G|ENSG00000209082|ENST00000386347|Transcript|upstream_gene_variant||||||rs2854128|524|1|MT-TL1|HGNC|7490|Mt_tRNA|YES|||||||||||A:0.1656|||||||||||||,G|ENSG00000198804|ENST00000361624|Transcript|upstream_gene_variant||||||rs2854128|3198|1|MT-CO1|HGNC|7419|protein_coding|YES||ENSP00000354499|COX1_HUMAN|Q957U9_HUMAN&Q7GXY8_HUMAN&M9Z2G2_HUMAN&Q8HBX8_HUMAN&Q5Q1W2_HUMAN&Q4R1L4_HUMAN&Q14XD3_HUMAN&Q14X83_HUMAN&F8U4W0_HUMAN&D3WYY6_HUMAN&D3WYY5_HUMAN&D3WYY4_HUMAN&D2Y6W4_HUMAN&C8YAE4_HUMAN&C3UPN2_HUMAN&B7TCT8_HUMAN&B2Y9D8_HUMAN&A5YMT3_HUMAN&A1XP63_HUMAN&A0S1I7_HUMAN|UPI0000000AA3||||||A:0.1656|||||||||||||,G|ENSG00000210154|ENST00000387419|Transcript|upstream_gene_variant||||||rs2854128|4812|1|MT-TD|HGNC|7478|Mt_tRNA|YES|||||||||||A:0.1656|||||||||||||,G|ENSG00000210112|ENST00000387377|Transcript|upstream_gene_variant||||||rs2854128|1696|1|MT-TM|HGNC|7492|Mt_tRNA|YES|||||||||||A:0.1656|||||||||||||,G|ENSG00000210135|ENST00000387400|Transcript|downstream_gene_variant||||||rs2854128|2951|-1|MT-TN|HGNC|7493|Mt_tRNA|YES|||||||||||A:0.1656|||||||||||||,G|ENSG00000210100|ENST00000387365|Transcript|upstream_gene_variant||||||rs2854128|1557|1|MT-TI|HGNC|7488|Mt_tRNA|YES|||||||||||A:0.1656|||||||||||||;GR=3.07;PH=0.654;PS=0.002 GT:GL:GOF:GQ:NR:NV 1/1:-300,-298.01,0:3:99:2733:2718 1/1:-300,-298.01,0:17:99:6509:6461 1/1:-300,-298.01,0:2:99:6598:6575 MT 2591 2747 rRNA" > exp $BT intersect -a bug44_a.vcf.gz -b bug44_b.bed -wa -wb > obs check exp obs rm exp obs ################################################################## # Test basic -f functionality ################################################################## echo -e " intersect.t52...\c" echo "chr1 10 12 a1 1 + chr2 10 12 a2 1 -" > exp $BT intersect -a x.bed -b y.bed -f 0.2 > obs check exp obs rm exp obs echo -e " intersect.t53...\c" echo -n "" > exp $BT intersect -a x.bed -b y.bed -f 0.21 > obs check exp obs rm exp obs ################################################################## # Test basic -F functionality ################################################################## echo -e " intersect.t54...\c" echo "chr1 10 20 a1 1 + chr1 8 12 b1 1 + chr2 10 20 a2 1 - chr2 8 12 b2 1 +" > exp $BT intersect -a x.bed -b y.bed -F 0.21 -wa -wb > obs check exp obs rm exp obs ################################################################## # Test basic -f with -F ################################################################## echo -e " intersect.t55...\c" echo -n "" > exp $BT intersect -a x.bed -b y.bed -f 0.21 -F 0.21 -wa -wb > obs check exp obs rm exp obs echo -e " intersect.t56...\c" echo -n "" > exp $BT intersect -a x.bed -b y.bed -f 0.21 -r -wa -wb > obs check exp obs rm exp obs echo -e " intersect.t57...\c" echo "chr1 10 20 a1 1 + chr1 8 12 b1 1 + chr2 10 20 a2 1 - chr2 8 12 b2 1 +" > exp $BT intersect -a x.bed -b y.bed -f 0.19 -r -wa -wb > obs check exp obs rm exp obs echo -e " intersect.t58...\c" echo "chr1 10 20 a1 1 + chr1 8 12 b1 1 + chr2 10 20 a2 1 - chr2 8 12 b2 1 +" > exp $BT intersect -a x.bed -b y.bed -F 0.50 -wa -wb > obs check exp obs rm exp obs echo -e " intersect.t59...\c" echo "chr1 10 20 a1 1 + chr1 8 12 b1 1 + chr2 10 20 a2 1 - chr2 8 12 b2 1 +" > exp $BT intersect -a x.bed -b y.bed -f 0.19 -F 0.21 -wa -wb > obs check exp obs rm exp obs echo -e " intersect.t60...\c" echo "chr1 10 20 a1 1 + chr1 8 12 b1 1 + chr2 10 20 a2 1 - chr2 8 12 b2 1 +" > exp $BT intersect -a x.bed -b y.bed -f 0.19 -F 0.21 -wa -wb > obs check exp obs rm exp obs echo -e " intersect.t61...\c" echo "chr1 10 20 a1 1 + chr1 8 12 b1 1 + chr2 10 20 a2 1 - chr2 8 12 b2 1 +" > exp $BT intersect -a x.bed -b y.bed -f 0.19 -F 0.50 -wa -wb > obs check exp obs rm exp obs echo -e " intersect.t62...\c" echo -n "" > exp $BT intersect -a x.bed -b y.bed -f 0.19 -F 0.51 -wa -wb > obs check exp obs rm exp obs ################################################################## # Test basic -f with -F with BAM ################################################################## echo -e " intersect.t63...\c" echo -n "" > exp $BT intersect -a x.bam -b y.bed -f 0.21 -F 0.21 -wa | $htsutil viewbamrecords > obs check exp obs rm exp obs echo -e " intersect.t64...\c" echo "a1 0 chr1 11 255 10M * 0 0 * * a2 16 chr2 11 255 10M * 0 0 * *" > exp $BT intersect -a x.bam -b y.bed -f 0.19 -F 0.21 -wa | $htsutil viewbamrecords > obs check exp obs rm exp obs echo -e " intersect.t65...\c" echo "a1 0 chr1 11 255 10M * 0 0 * * a2 16 chr2 11 255 10M * 0 0 * *" > exp $BT intersect -a x.bam -b y.bed -f 0.19 -F 0.21 -wa | $htsutil viewbamrecords > obs check exp obs rm exp obs echo -e " intersect.t66...\c" echo "a1 0 chr1 11 255 10M * 0 0 * * a2 16 chr2 11 255 10M * 0 0 * *" > exp $BT intersect -a x.bam -b y.bed -f 0.19 -F 0.50 -wa | $htsutil viewbamrecords > obs check exp obs rm exp obs echo -e " intersect.t67...\c" echo -n "" > exp $BT intersect -a x.bam -b y.bed -f 0.19 -F 0.51 -wa | $htsutil viewbamrecords > obs check exp obs rm exp obs ################################################################## # Test basic -f with -F and -e ################################################################## echo -e " intersect.t68...\c" echo "chr1 10 20 a1 1 + chr1 8 12 b1 1 + chr2 10 20 a2 1 - chr2 8 12 b2 1 +" > exp $BT intersect -a x.bed -b y.bed -f 0.21 -F 0.21 -wa -wb -e > obs check exp obs rm exp obs ################################################################## # Test basic -split with BED12 w/ and w/o trailing commas for blocks # Issue 366 ################################################################## echo -e " intersect.t69...\c" echo "chr1 0 45 oneblock_comma 0 + 0 0 0 1 45, 0, chr1 0 45 oneblock_comma 0 + 0 0 0 1 45, 0, chr1 0 45 oneblock_comma 0 + 0 0 0 1 45, 0, chr1 0 45 oneblock_comma 0 + 0 0 0 1 45, 0, chr1 0 45 oneblock_nocomma 0 + 0 0 0 1 45 0 chr1 0 45 oneblock_nocomma 0 + 0 0 0 1 45 0 chr1 0 45 oneblock_nocomma 0 + 0 0 0 1 45 0 chr1 0 45 oneblock_nocomma 0 + 0 0 0 1 45 0 chr1 0 45 three_blocks_comma 0 + 0 0 0 3 10,10,10, 0,20,40, chr1 0 45 three_blocks_comma 0 + 0 0 0 3 10,10,10, 0,20,40, chr1 0 50 three_blocks_comma 0 + 0 0 0 3 10,10,10, 0,20,40, chr1 0 50 three_blocks_comma 0 + 0 0 0 3 10,10,10, 0,20,40, chr1 0 45 three_blocks_nocomma 0 + 0 0 0 3 10,10,10 0,20,40 chr1 0 45 three_blocks_nocomma 0 + 0 0 0 3 10,10,10 0,20,40 chr1 0 50 three_blocks_nocomma 0 + 0 0 0 3 10,10,10 0,20,40 chr1 0 50 three_blocks_nocomma 0 + 0 0 0 3 10,10,10 0,20,40" > exp $BT intersect -a blocks.bed12 -b blocks.bed12 -split > obs check exp obs rm exp obs ################################################################## # Issue 311 ################################################################## echo -e " intersect.t70...\c" echo "1 31 32 1 32 . A T 0 PASS DP=22" > exp $BT intersect -a a.issue311.bed -b b.issue311.vcf -wb > obs check exp obs rm exp obs echo -e " intersect.t71...\c" echo "1 31 32 1 pseudogene exon 32 32 . - . gene_id \"ENSG00000224777\"; transcript_id \"ENST00000424047\"; exon_number \"1\"; gene_name \"OR4F2P\"; transcript_name \"OR4F2P-001\";" > exp $BT intersect -a a.issue311.bed -b b.issue311.gff -wb > obs check exp obs rm exp obs # GFF ---------- # BED ----------- echo -e " intersect.t72...\c" echo "1 . . 16 20 . - . ." > exp $BT intersect -a <(echo -e "1\t.\t.\t10\t20\t.\t-\t.\t.") -b <(echo -e "1\t15\t25") > obs check exp obs rm exp obs # BED ---------- # GFF ----------- echo -e " intersect.t73...\c" echo "1 15 20" > exp $BT intersect -a <(echo -e "1\t15\t25") -b <(echo -e "1\t.\t.\t10\t20\t.\t-\t.\t.") > obs check exp obs rm exp obs # GFF ---------- # BED ----------- echo -e " intersect.t74...\c" echo "1 . . 15 20 . - . ." > exp $BT intersect -a <(echo -e "1\t.\t.\t15\t25\t.\t-\t.\t.") -b <(echo -e "1\t10\t20") > obs check exp obs rm exp obs # BED ---------- # GFF ----------- echo -e " intersect.t75...\c" echo "1 15 20" > exp $BT intersect -a <(echo -e "1\t15\t25") -b <(echo -e "1\t.\t.\t10\t20\t.\t-\t.\t.") > obs check exp obs rm exp obs # GFF ---------- # BED ------------------- echo -e " intersect.t76...\c" echo "1 . . 15 20 . - . ." > exp $BT intersect -a <(echo -e "1\t.\t.\t15\t20\t.\t-\t.\t.") -b <(echo -e "1\t10\t25") > obs check exp obs rm exp obs # BED ---------- # GFF -------------------- echo -e " intersect.t77...\c" echo "1 15 20" > exp $BT intersect -a <(echo -e "1\t15\t20") -b <(echo -e "1\t.\t.\t10\t25\t.\t-\t.\t.") > obs check exp obs rm exp obs # GFF ---------- # BED ------------------- echo -e " intersect.t78...\c" echo "1 . . 16 20 . - . ." > exp $BT intersect -a <(echo -e "1\t.\t.\t10\t25\t.\t-\t.\t.") -b <(echo -e "1\t15\t20") > obs check exp obs rm exp obs # BED ---------- # GFF -------------------- echo -e " intersect.t79...\c" echo "1 14 20" > exp $BT intersect -a <(echo -e "1\t10\t25") -b <(echo -e "1\t.\t.\t15\t20\t.\t-\t.\t.") > obs check exp obs rm exp obs # Make sure 1bp of overlap is reported for a VCF SNP and 1-bp overlapping BED. echo -e " intersect.t80...\c" echo "chr1 1 . G C . . RS=797045043 chr1 0 1 1" > exp $BT intersect -a jim.vcf -b jim.bed -wo > obs check exp obs rm exp obs ################################################################## # Issue 316. SVLEN and END ################################################################## echo -e " intersect.t81...\c" echo "##fileformat=VCF4.1 #CHROM POS ID REF ALT QUAL FILTER INFO 1 32 . A 0 PASS DP=22;END=52" > a echo "##fileformat=VCF4.1 #CHROM POS ID REF ALT QUAL FILTER INFO 1 52 . A T 0 PASS DP=22;SVLEN=100" > b echo "1 32 . A 0 PASS DP=22;END=52" > exp $BT intersect -a a -b b > obs check exp obs rm exp obs a b echo -e " intersect.t82...\c" echo "##fileformat=VCF4.1 #CHROM POS ID REF ALT QUAL FILTER INFO 1 32 . A 0 PASS DP=22;END=51" > a echo "##fileformat=VCF4.1 #CHROM POS ID REF ALT QUAL FILTER INFO 1 52 . A T 0 PASS DP=22;SVLEN=100" > b echo -n "" > exp $BT intersect -a a -b b > obs check exp obs rm exp obs a b echo -e " intersect.t83...\c" $BT intersect -wa -a issue-919.bed -b issue-919.region.bed > obs echo -e "chr1 46626685 46645317 1527 4.01 . 46626685 46645317 128,0,128 102 1,104,89,167,139,135,140,141,107,94,153,178,132,162,163,147,131,133,187,146,201,242,98,156,171,167,163,153,143,143,156,143,155,119,142,139,157,94,201,163,163,160,157,154,129,147,163,158,151,170,133,144,146,151,168,132,319,205,149,132,161,153,146,140,166,130,153,151,100,179,158,156,189,178,141,130,136,168,146,176,157,124,131,166,175,152,201,184,111,123,212,148,169,340,166,260,141,154,156,139,159,1 0,99,223,403,601,794,938,1124,1324,1527,1633,1787,2021,2176,2347,2522,2752,2931,3079,3276,3434,3636,3879,3987,4146,4352,4550,4740,4915,5069,5235,5441,5600,5780,5919,6097,6264,6490,6599,6805,6969,7177,7384,7559,7766,7929,8077,8275,8469,8640,8859,9012,9163,9341,9544,9713,9902,10222,10447,10600,10788,10969,11149,11314,11479,11699,11882,12065,12297,12431,12625,12793,12955,13145,13344,13517,13681,13822,14018,14205,14382,14580,14733,14910,15094,15272,15462,15667,15852,16022,16173,16406,16593,16827,17168,17335,17690,17834,18082,18264,18442,18631" > exp check exp obs rm exp obs STARTWD=$(pwd); for ADDITIONAL_TEST in \ new_test-intersect.sh \ multi_intersect/test-multi_intersect.sh \ sortAndNaming/test-sort-and-naming.sh \ ; do # In case the cd operation fails, combine it with the script execution cd $(dirname "${STARTWD}/${ADDITIONAL_TEST}") \ && bash $(basename "${STARTWD}/${ADDITIONAL_TEST}") \ || FAILURES=$(expr $FAILURES + 1); done [[ $FAILURES -eq 0 ]] || exit 1; chr2 1000 16385 A 0 - 0 0 0 2 1,1, 0,15384, chr1 43250001 47250000 ?uRa_gzipped.bedK(24442L28!" !.,&chr1 0 1 chr1 10 20 345.7 ##fileformat=VCF4.1 #CHROM POS ID REF ALT QUAL FILTER INFO 1 32 . A T 0 PASS DP=22 chr1 20 30 chr1 40 50 chr1 15 60 chr1 70 80 1 1 1000 aaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaa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chr1 10 20 a1 1 + chr2 10 20 a2 1 - 9 141151174 141151213 Low_complexity 9 141151355 141151475 LINE 9 141151514 141151815 SINE 9 141151817 141151937 SINE 9 141152314 141152378 Simple_repeat 9 141152592 141152787 SINE 9 141152832 141153431 LTR MT 2591 2747 rRNA MT 3230 3308 tRNA MT 4329 4401 tRNA MT 7448 7515 tRNA X 67103806 67109934 LINE X 134217438 134217916 LTR X 8388422 8388715 SINE X 16777024 16777338 SINE X 25165534 25165834 LINE X 41942860 41943542 LINE X 50331587 50331685 SINE X 75496377 75497894 LINE chr1 10 60 three_blocks_nomatch 0 + 0 0 0 3 11,10,10, 0,20,40, @HD VN:1.0 GO:none SO:coordinate @SQ SN:chr1 LN:249250621 one_block_one_exon_30bp 16 chr1 1 40 30M * 0 0 GAAGGCCACCGCCGCGGTTATTTTCCTTCA CCCDDB?=FJIIJIGFJIJHIJJJJJJJJI MD:Z:50 one_block_one_exon_20bp 16 chr1 81 40 30M * 0 0 GAAGGCCACCGCCGCGGTTATTTTCCTTCA CCCDDB?=FJIIJIGFJIJHIJJJJJJJJI MD:Z:50 two_blocks_two_exons 16 chr1 91 40 10M100N20M * 0 0 GAAGGCCACCGCCGCGGTTATTTTCCTTCA CCCDDB?=FJIIJIGFJIJHIJJJJJJJJI MD:Z:50 chr1 0 45 oneblock_comma 0 + 0 0 0 1 45, 0, chr1 0 45 oneblock_nocomma 0 + 0 0 0 1 45 0 chr1 0 50 three_blocks_comma 0 + 0 0 0 3 10,10,10, 0,20,40, chr1 0 50 three_blocks_nocomma 0 + 0 0 0 3 10,10,10 0,20,401 500 600 c4 cq# This is line 0 of a file with a large header. # This is line 1 of a file with a large header. # This is line 2 of a file with a large header. # This is line 3 of a file with a large header. # This is line 4 of a file with a large header. # This is line 5 of a file with a large header. # This is line 6 of a file with a large header. # This is line 7 of a file with a large header. # This is line 8 of a file with a large header. # This is line 9 of a file with a large header. # This is line 10 of a file with a large header. # This is line 11 of a file with a large header. # This is line 12 of a file with a large header. # This is line 13 of a file with a large header. # This is line 14 of a file with a large header. # This is line 15 of a file with a large header. # This is line 16 of a file with a large header. # This is line 17 of a file with a large header. # This is line 18 of a file with a large header. # This is line 19 of a file with a large header. # This is line 20 of a file with a large header. # This is line 21 of a file with a large header. # This is line 22 of a file with a large header. # This is line 23 of a file with a large header. # This is line 24 of a file with a large header. # This is line 25 of a file with a large header. # This is line 26 of a file with a large header. # This is line 27 of a file with a large header. # This is line 28 of a file with a large header. # This is line 29 of a file with a large header. # This is line 30 of a file with a large header. # This is line 31 of a file with a large header. # This is line 32 of a file with a large header. # This is line 33 of a file with a large header. # This is line 34 of a file with a large header. # This is line 35 of a file with a large header. # This is line 36 of a file with a large header. # This is line 37 of a file with a large header. # This is line 38 of a file with a large header. # This is line 39 of a file with a large header. # This is line 40 of a file with a large header. # This is line 41 of a file with a large header. # This is line 42 of a file with a large header. # This is line 43 of a file with a large header. # This is line 44 of a file with a large header. # This is line 45 of a file with a large header. # This is line 46 of a file with a large header. # This is line 47 of a file with a large header. # This is line 48 of a file with a large header. # This is line 49 of a file with a large header. # This is line 50 of a file with a large header. # This is line 51 of a file with a large header. # This is line 52 of a file with a large header. # This is line 53 of a file with a large header. # This is line 54 of a file with a large header. # This is line 55 of a file with a large header. # This is line 56 of a file with a large header. # This is line 57 of a file with a large header. # This is line 58 of a file with a large header. # This is line 59 of a file with a large header. # This is line 60 of a file with a large header. # This is line 61 of a file with a large header. # This is line 62 of a file with a large header. # This is line 63 of a file with a large header. # This is line 64 of a file with a large header. # This is line 65 of a file with a large header. # This is line 66 of a file with a large header. # This is line 67 of a file with a large header. # This is line 68 of a file with a large header. # This is line 69 of a file with a large header. # This is line 70 of a file with a large header. # This is line 71 of a file with a large header. # This is line 72 of a file with a large header. # This is line 73 of a file with a large header. # This is line 74 of a file with a large header. # This is line 75 of a file with a large header. # This is line 76 of a file with a large header. # This is line 77 of a file with a large header. # This is line 78 of a file with a large header. # This is line 79 of a file with a large header. # This is line 80 of a file with a large header. # This is line 81 of a file with a large header. # This is line 82 of a file with a large header. # This is line 83 of a file with a large header. # This is line 84 of a file with a large header. # This is line 85 of a file with a large header. # This is line 86 of a file with a large header. # This is line 87 of a file with a large header. # This is line 88 of a file with a large header. # This is line 89 of a file with a large header. # This is line 90 of a file with a large header. # This is line 91 of a file with a large header. # This is line 92 of a file with a large header. # This is line 93 of a file with a large header. # This is line 94 of a file with a large header. # This is line 95 of a file with a large header. # This is line 96 of a file with a large header. # This is line 97 of a file with a large header. # This is line 98 of a file with a large header. # This is line 99 of a file with a large header. # This is line 100 of a file with a large header. # This is line 101 of a file with a large header. # This is line 102 of a file with a large header. # This is line 103 of a file with a large header. # This is line 104 of a file with a large header. # This is line 105 of a file with a large header. # This is line 106 of a file with a large header. # This is line 107 of a file with a large header. # This is line 108 of a file with a large header. # This is line 109 of a file with a large header. # This is line 110 of a file with a large header. # This is line 111 of a file with a large header. # This is line 112 of a file with a large header. # This is line 113 of a file with a large header. # This is line 114 of a file with a large header. # This is line 115 of a file with a large header. # This is line 116 of a file with a large header. # This is line 117 of a file with a large header. # This is line 118 of a file with a large header. # This is line 119 of a file with a large header. # This is line 120 of a file with a large header. # This is line 121 of a file with a large header. # This is line 122 of a file with a large header. # This is line 123 of a file with a large header. # This is line 124 of a file with a large header. # This is line 125 of a file with a large header. # This is line 126 of a file with a large header. # This is line 127 of a file with a large header. # This is line 128 of a file with a large header. # This is line 129 of a file with a large header. # This is line 130 of a file with a large header. # This is line 131 of a file with a large header. # This is line 132 of a file with a large header. # This is line 133 of a file with a large header. # This is line 134 of a file with a large header. # This is line 135 of a file with a large header. # This is line 136 of a file with a large header. # This is line 137 of a file with a large header. # This is line 138 of a file with a large header. # This is line 139 of a file with a large header. # This is line 140 of a file with a large header. # This is line 141 of a file with a large header. # This is line 142 of a file with a large header. # This is line 143 of a file with a large header. # This is line 144 of a file with a large header. # This is line 145 of a file with a large header. # This is line 146 of a file with a large header. # This is line 147 of a file with a large header. # This is line 148 of a file with a large header. # This is line 149 of a file with a large header. # This is line 150 of a file with a large header. # This is line 151 of a file with a large header. # This is line 152 of a file with a large header. # This is line 153 of a file with a large header. # This is line 154 of a file with a large header. # This is line 155 of a file with a large header. # This is line 156 of a file with a large header. # This is line 157 of a file with a large header. # This is line 158 of a file with a large header. # This is line 159 of a file with a large header. # This is line 160 of a file with a large header. # This is line 161 of a file with a large header. # This is line 162 of a file with a large header. # This is line 163 of a file with a large header. # This is line 164 of a file with a large header. # This is line 165 of a file with a large header. # This is line 166 of a file with a large header. # This is line 167 of a file with a large header. # This is line 168 of a file with a large header. # This is line 169 of a file with a large header. # This is line 170 of a file with a large header. # This is line 171 of a file with a large header. # This is line 172 of a file with a large header. # This is line 173 of a file with a large header. # This is line 174 of a file with a large header. # This is line 175 of a file with a large header. # This is line 176 of a file with a large header. # This is line 177 of a file with a large header. # This is line 178 of a file with a large header. # This is line 179 of a file with a large header. # This is line 180 of a file with a large header. # This is line 181 of a file with a large header. # This is line 182 of a file with a large header. # This is line 183 of a file with a large header. # This is line 184 of a file with a large header. # This is line 185 of a file with a large header. # This is line 186 of a file with a large header. # This is line 187 of a file with a large header. # This is line 188 of a file with a large header. # This is line 189 of a file with a large header. # This is line 190 of a file with a large header. # This is line 191 of a file with a large header. # This is line 192 of a file with a large header. # This is line 193 of a file with a large header. # This is line 194 of a file with a large header. # This is line 195 of a file with a large header. # This is line 196 of a file with a large header. # This is line 197 of a file with a large header. # This is line 198 of a file with a large header. # This is line 199 of a file with a large header. # This is line 200 of a file with a large header. # This is line 201 of a file with a large header. # This is line 202 of a file with a large header. # This is line 203 of a file with a large header. # This is line 204 of a file with a large header. # This is line 205 of a file with a large header. # This is line 206 of a file with a large header. # This is line 207 of a file with a large header. # This is line 208 of a file with a large header. # This is line 209 of a file with a large header. # This is line 210 of a file with a large header. # This is line 211 of a file with a large header. # This is line 212 of a file with a large header. # This is line 213 of a file with a large header. # This is line 214 of a file with a large header. # This is line 215 of a file with a large header. # This is line 216 of a file with a large header. # This is line 217 of a file with a large header. # This is line 218 of a file with a large header. # This is line 219 of a file with a large header. # This is line 220 of a file with a large header. # This is line 221 of a file with a large header. # This is line 222 of a file with a large header. # This is line 223 of a file with a large header. # This is line 224 of a file with a large header. # This is line 225 of a file with a large header. # This is line 226 of a file with a large header. # This is line 227 of a file with a large header. # This is line 228 of a file with a large header. # This is line 229 of a file with a large header. # This is line 230 of a file with a large header. # This is line 231 of a file with a large header. # This is line 232 of a file with a large header. # This is line 233 of a file with a large header. # This is line 234 of a file with a large header. # This is line 235 of a file with a large header. # This is line 236 of a file with a large header. # This is line 237 of a file with a large header. # This is line 238 of a file with a large header. # This is line 239 of a file with a large header. # This is line 240 of a file with a large header. # This is line 241 of a file with a large header. # This is line 242 of a file with a large header. # This is line 243 of a file with a large header. # This is line 244 of a file with a large header. # This is line 245 of a file with a large header. # This is line 246 of a file with a large header. # This is line 247 of a file with a large header. # This is line 248 of a file with a large header. # This is line 249 of a file with a large header. # This is line 250 of a file with a large header. # This is line 251 of a file with a large header. # This is line 252 of a file with a large header. # This is line 253 of a file with a large header. # This is line 254 of a file with a large header. # This is line 255 of a file with a large header. # This is line 256 of a file with a large header. # This is line 257 of a file with a large header. # This is line 258 of a file with a large header. # This is line 259 of a file with a large header. # This is line 260 of a file with a large header. # This is line 261 of a file with a large header. # This is line 262 of a file with a large header. # This is line 263 of a file with a large header. # This is line 264 of a file with a large header. # This is line 265 of a file with a large header. # This is line 266 of a file with a large header. # This is line 267 of a file with a large header. # This is line 268 of a file with a large header. # This is line 269 of a file with a large header. # This is line 270 of a file with a large header. # This is line 271 of a file with a large header. # This is line 272 of a file with a large header. # This is line 273 of a file with a large header. # This is line 274 of a file with a large header. # This is line 275 of a file with a large header. # This is line 276 of a file with a large header. # This is line 277 of a file with a large header. # This is line 278 of a file with a large header. # This is line 279 of a file with a large header. # This is line 280 of a file with a large header. # This is line 281 of a file with a large header. # This is line 282 of a file with a large header. # This is line 283 of a file with a large header. # This is line 284 of a file with a large header. # This is line 285 of a file with a large header. # This is line 286 of a file with a large header. # This is line 287 of a file with a large header. # This is line 288 of a file with a large header. # This is line 289 of a file with a large header. # This is line 290 of a file with a large header. # This is line 291 of a file with a large header. # This is line 292 of a file with a large header. # This is line 293 of a file with a large header. # This is line 294 of a file with a large header. # This is line 295 of a file with a large header. # This is line 296 of a file with a large header. # This is line 297 of a file with a large header. # This is line 298 of a file with a large header. # This is line 299 of a file with a large header. # This is line 300 of a file with a large header. # This is line 301 of a file with a large header. # This is line 302 of a file with a large header. # This is line 303 of a file with a large header. # This is line 304 of a file with a large header. # This is line 305 of a file with a large header. # This is line 306 of a file with a large header. # This is line 307 of a file with a large header. # This is line 308 of a file with a large header. # This is line 309 of a file with a large header. # This is line 310 of a file with a large header. # This is line 311 of a file with a large header. # This is line 312 of a file with a large header. # This is line 313 of a file with a large header. # This is line 314 of a file with a large header. # This is line 315 of a file with a large header. # This is line 316 of a file with a large header. # This is line 317 of a file with a large header. # This is line 318 of a file with a large header. # This is line 319 of a file with a large header. # This is line 320 of a file with a large header. # This is line 321 of a file with a large header. # This is line 322 of a file with a large header. # This is line 323 of a file with a large header. # This is line 324 of a file with a large header. # This is line 325 of a file with a large header. # This is line 326 of a file with a large header. # This is line 327 of a file with a large header. # This is line 328 of a file with a large header. # This is line 329 of a file with a large header. # This is line 330 of a file with a large header. # This is line 331 of a file with a large header. # This is line 332 of a file with a large header. # This is line 333 of a file with a large header. # This is line 334 of a file with a large header. # This is line 335 of a file with a large header. # This is line 336 of a file with a large header. # This is line 337 of a file with a large header. # This is line 338 of a file with a large header. # This is line 339 of a file with a large header. # This is line 340 of a file with a large header. # This is line 341 of a file with a large header. # This is line 342 of a file with a large header. # This is line 343 of a file with a large header. # This is line 344 of a file with a large header. # This is line 345 of a file with a large header. # This is line 346 of a file with a large header. # This is line 347 of a file with a large header. # This is line 348 of a file with a large header. # This is line 349 of a file with a large header. # This is line 350 of a file with a large header. # This is line 351 of a file with a large header. # This is line 352 of a file with a large header. # This is line 353 of a file with a large header. # This is line 354 of a file with a large header. # This is line 355 of a file with a large header. # This is line 356 of a file with a large header. # This is line 357 of a file with a large header. # This is line 358 of a file with a large header. # This is line 359 of a file with a large header. # This is line 360 of a file with a large header. # This is line 361 of a file with a large header. # This is line 362 of a file with a large header. # This is line 363 of a file with a large header. # This is line 364 of a file with a large header. # This is line 365 of a file with a large header. # This is line 366 of a file with a large header. # This is line 367 of a file with a large header. # This is line 368 of a file with a large header. # This is line 369 of a file with a large header. # This is line 370 of a file with a large header. # This is line 371 of a file with a large header. # This is line 372 of a file with a large header. # This is line 373 of a file with a large header. # This is line 374 of a file with a large header. # This is line 375 of a file with a large header. # This is line 376 of a file with a large header. # This is line 377 of a file with a large header. # This is line 378 of a file with a large header. # This is line 379 of a file with a large header. # This is line 380 of a file with a large header. # This is line 381 of a file with a large header. # This is line 382 of a file with a large header. # This is line 383 of a file with a large header. # This is line 384 of a file with a large header. # This is line 385 of a file with a large header. # This is line 386 of a file with a large header. # This is line 387 of a file with a large header. # This is line 388 of a file with a large header. # This is line 389 of a file with a large header. # This is line 390 of a file with a large header. # This is line 391 of a file with a large header. # This is line 392 of a file with a large header. # This is line 393 of a file with a large header. # This is line 394 of a file with a large header. # This is line 395 of a file with a large header. # This is line 396 of a file with a large header. # This is line 397 of a file with a large header. # This is line 398 of a file with a large header. # This is line 399 of a file with a large header. # This is line 400 of a file with a large header. # This is line 401 of a file with a large header. # This is line 402 of a file with a large header. # This is line 403 of a file with a large header. # This is line 404 of a file with a large header. # This is line 405 of a file with a large header. # This is line 406 of a file with a large header. # This is line 407 of a file with a large header. # This is line 408 of a file with a large header. # This is line 409 of a file with a large header. # This is line 410 of a file with a large header. # This is line 411 of a file with a large header. # This is line 412 of a file with a large header. # This is line 413 of a file with a large header. # This is line 414 of a file with a large header. # This is line 415 of a file with a large header. # This is line 416 of a file with a large header. # This is line 417 of a file with a large header. # This is line 418 of a file with a large header. # This is line 419 of a file with a large header. # This is line 420 of a file with a large header. # This is line 421 of a file with a large header. # This is line 422 of a file with a large header. # This is line 423 of a file with a large header. # This is line 424 of a file with a large header. # This is line 425 of a file with a large header. # This is line 426 of a file with a large header. # This is line 427 of a file with a large header. # This is line 428 of a file with a large header. # This is line 429 of a file with a large header. # This is line 430 of a file with a large header. # This is line 431 of a file with a large header. # This is line 432 of a file with a large header. # This is line 433 of a file with a large header. # This is line 434 of a file with a large header. # This is line 435 of a file with a large header. # This is line 436 of a file with a large header. # This is line 437 of a file with a large header. # This is line 438 of a file with a large header. # This is line 439 of a file with a large header. # This is line 440 of a file with a large header. # This is line 441 of a file with a large header. # This is line 442 of a file with a large header. # This is line 443 of a file with a large header. # This is line 444 of a file with a large header. # This is line 445 of a file with a large header. # This is line 446 of a file with a large header. # This is line 447 of a file with a large header. # This is line 448 of a file with a large header. # This is line 449 of a file with a large header. # This is line 450 of a file with a large header. # This is line 451 of a file with a large header. # This is line 452 of a file with a large header. # This is line 453 of a file with a large header. # This is line 454 of a file with a large header. # This is line 455 of a file with a large header. # This is line 456 of a file with a large header. # This is line 457 of a file with a large header. # This is line 458 of a file with a large header. # This is line 459 of a file with a large header. # This is line 460 of a file with a large header. # This is line 461 of a file with a large header. # This is line 462 of a file with a large header. # This is line 463 of a file with a large header. # This is line 464 of a file with a large header. # This is line 465 of a file with a large header. # This is line 466 of a file with a large header. # This is line 467 of a file with a large header. # This is line 468 of a file with a large header. # This is line 469 of a file with a large header. # This is line 470 of a file with a large header. # This is line 471 of a file with a large header. # This is line 472 of a file with a large header. # This is line 473 of a file with a large header. # This is line 474 of a file with a large header. # This is line 475 of a file with a large header. # This is line 476 of a file with a large header. # This is line 477 of a file with a large header. # This is line 478 of a file with a large header. # This is line 479 of a file with a large header. # This is line 480 of a file with a large header. # This is line 481 of a file with a large header. # This is line 482 of a file with a large header. # This is line 483 of a file with a large header. # This is line 484 of a file with a large header. # This is line 485 of a file with a large header. # This is line 486 of a file with a large header. # This is line 487 of a file with a large header. # This is line 488 of a file with a large header. # This is line 489 of a file with a large header. # This is line 490 of a file with a large header. # This is line 491 of a file with a large header. # This is line 492 of a file with a large header. # This is line 493 of a file with a large header. # This is line 494 of a file with a large header. # This is line 495 of a file with a large header. # This is line 496 of a file with a large header. # This is line 497 of a file with a large header. # This is line 498 of a file with a large header. # This is line 499 of a file with a large header. # This is line 500 of a file with a large header. # This is line 501 of a file with a large header. # This is line 502 of a file with a large header. # This is line 503 of a file with a large header. # This is line 504 of a file with a large header. # This is line 505 of a file with a large header. # This is line 506 of a file with a large header. # This is line 507 of a file with a large header. # This is line 508 of a file with a large header. # This is line 509 of a file with a large header. # This is line 510 of a file with a large header. # This is line 511 of a file with a large header. # This is line 512 of a file with a large header. # This is line 513 of a file with a large header. # This is line 514 of a file with a large header. # This is line 515 of a file with a large header. # This is line 516 of a file with a large header. # This is line 517 of a file with a large header. # This is line 518 of a file with a large header. # This is line 519 of a file with a large header. # This is line 520 of a file with a large header. # This is line 521 of a file with a large header. # This is line 522 of a file with a large header. # This is line 523 of a file with a large header. # This is line 524 of a file with a large header. # This is line 525 of a file with a large header. # This is line 526 of a file with a large header. # This is line 527 of a file with a large header. # This is line 528 of a file with a large header. # This is line 529 of a file with a large header. # This is line 530 of a file with a large header. # This is line 531 of a file with a large header. # This is line 532 of a file with a large header. # This is line 533 of a file with a large header. # This is line 534 of a file with a large header. # This is line 535 of a file with a large header. # This is line 536 of a file with a large header. # This is line 537 of a file with a large header. # This is line 538 of a file with a large header. # This is line 539 of a file with a large header. # This is line 540 of a file with a large header. # This is line 541 of a file with a large header. # This is line 542 of a file with a large header. # This is line 543 of a file with a large header. # This is line 544 of a file with a large header. # This is line 545 of a file with a large header. # This is line 546 of a file with a large header. # This is line 547 of a file with a large header. # This is line 548 of a file with a large header. # This is line 549 of a file with a large header. # This is line 550 of a file with a large header. # This is line 551 of a file with a large header. # This is line 552 of a file with a large header. # This is line 553 of a file with a large header. # This is line 554 of a file with a large header. # This is line 555 of a file with a large header. # This is line 556 of a file with a large header. # This is line 557 of a file with a large header. # This is line 558 of a file with a large header. # This is line 559 of a file with a large header. # This is line 560 of a file with a large header. # This is line 561 of a file with a large header. # This is line 562 of a file with a large header. # This is line 563 of a file with a large header. # This is line 564 of a file with a large header. # This is line 565 of a file with a large header. # This is line 566 of a file with a large header. # This is line 567 of a file with a large header. # This is line 568 of a file with a large header. # This is line 569 of a file with a large header. # This is line 570 of a file with a large header. # This is line 571 of a file with a large header. # This is line 572 of a file with a large header. # This is line 573 of a file with a large header. # This is line 574 of a file with a large header. # This is line 575 of a file with a large header. # This is line 576 of a file with a large header. # This is line 577 of a file with a large header. # This is line 578 of a file with a large header. # This is line 579 of a file with a large header. # This is line 580 of a file with a large header. # This is line 581 of a file with a large header. # This is line 582 of a file with a large header. # This is line 583 of a file with a large header. # This is line 584 of a file with a large header. # This is line 585 of a file with a large header. # This is line 586 of a file with a large header. # This is line 587 of a file with a large header. # This is line 588 of a file with a large header. # This is line 589 of a file with a large header. # This is line 590 of a file with a large header. # This is line 591 of a file with a large header. # This is line 592 of a file with a large header. # This is line 593 of a file with a large header. # This is line 594 of a file with a large header. # This is line 595 of a file with a large header. # This is line 596 of a file with a large header. # This is line 597 of a file with a large header. # This is line 598 of a file with a large header. # This is line 599 of a file with a large header. # This is line 600 of a file with a large header. # This is line 601 of a file with a large header. # This is line 602 of a file with a large header. # This is line 603 of a file with a large header. # This is line 604 of a file with a large header. # This is line 605 of a file with a large header. # This is line 606 of a file with a large header. # This is line 607 of a file with a large header. # This is line 608 of a file with a large header. # This is line 609 of a file with a large header. # This is line 610 of a file with a large header. # This is line 611 of a file with a large header. # This is line 612 of a file with a large header. # This is line 613 of a file with a large header. # This is line 614 of a file with a large header. # This is line 615 of a file with a large header. # This is line 616 of a file with a large header. # This is line 617 of a file with a large header. # This is line 618 of a file with a large header. # This is line 619 of a file with a large header. # This is line 620 of a file with a large header. # This is line 621 of a file with a large header. # This is line 622 of a file with a large header. # This is line 623 of a file with a large header. # This is line 624 of a file with a large header. # This is line 625 of a file with a large header. # This is line 626 of a file with a large header. # This is line 627 of a file with a large header. # This is line 628 of a file with a large header. # This is line 629 of a file with a large header. # This is line 630 of a file with a large header. # This is line 631 of a file with a large header. # This is line 632 of a file with a large header. # This is line 633 of a file with a large header. # This is line 634 of a file with a large header. # This is line 635 of a file with a large header. # This is line 636 of a file with a large header. # This is line 637 of a file with a large header. # This is line 638 of a file with a large header. # This is line 639 of a file with a large header. # This is line 640 of a file with a large header. # This is line 641 of a file with a large header. # This is line 642 of a file with a large header. # This is line 643 of a file with a large header. # This is line 644 of a file with a large header. # This is line 645 of a file with a large header. # This is line 646 of a file with a large header. # This is line 647 of a file with a large header. # This is line 648 of a file with a large header. # This is line 649 of a file with a large header. # This is line 650 of a file with a large header. # This is line 651 of a file with a large header. # This is line 652 of a file with a large header. # This is line 653 of a file with a large header. # This is line 654 of a file with a large header. # This is line 655 of a file with a large header. # This is line 656 of a file with a large header. # This is line 657 of a file with a large header. # This is line 658 of a file with a large header. # This is line 659 of a file with a large header. # This is line 660 of a file with a large header. # This is line 661 of a file with a large header. # This is line 662 of a file with a large header. # This is line 663 of a file with a large header. # This is line 664 of a file with a large header. # This is line 665 of a file with a large header. # This is line 666 of a file with a large header. # This is line 667 of a file with a large header. # This is line 668 of a file with a large header. # This is line 669 of a file with a large header. # This is line 670 of a file with a large header. # This is line 671 of a file with a large header. # This is line 672 of a file with a large header. # This is line 673 of a file with a large header. # This is line 674 of a file with a large header. # This is line 675 of a file with a large header. # This is line 676 of a file with a large header. # This is line 677 of a file with a large header. # This is line 678 of a file with a large header. # This is line 679 of a file with a large header. # This is line 680 of a file with a large header. # This is line 681 of a file with a large header. # This is line 682 of a file with a large header. # This is line 683 of a file with a large header. # This is line 684 of a file with a large header. # This is line 685 of a file with a large header. # This is line 686 of a file with a large header. # This is line 687 of a file with a large header. # This is line 688 of a file with a large header. # This is line 689 of a file with a large header. # This is line 690 of a file with a large header. # This is line 691 of a file with a large header. # This is line 692 of a file with a large header. # This is line 693 of a file with a large header. # This is line 694 of a file with a large header. # This is line 695 of a file with a large header. # This is line 696 of a file with a large header. # This is line 697 of a file with a large header. # This is line 698 of a file with a large header. # This is line 699 of a file with a large header. # This is line 700 of a file with a large header. # This is line 701 of a file with a large header. # This is line 702 of a file with a large header. # This is line 703 of a file with a large header. # This is line 704 of a file with a large header. # This is line 705 of a file with a large header. # This is line 706 of a file with a large header. # This is line 707 of a file with a large header. # This is line 708 of a file with a large header. # This is line 709 of a file with a large header. # This is line 710 of a file with a large header. # This is line 711 of a file with a large header. # This is line 712 of a file with a large header. # This is line 713 of a file with a large header. # This is line 714 of a file with a large header. # This is line 715 of a file with a large header. # This is line 716 of a file with a large header. # This is line 717 of a file with a large header. # This is line 718 of a file with a large header. # This is line 719 of a file with a large header. # This is line 720 of a file with a large header. # This is line 721 of a file with a large header. # This is line 722 of a file with a large header. # This is line 723 of a file with a large header. # This is line 724 of a file with a large header. # This is line 725 of a file with a large header. # This is line 726 of a file with a large header. # This is line 727 of a file with a large header. # This is line 728 of a file with a large header. # This is line 729 of a file with a large header. # This is line 730 of a file with a large header. # This is line 731 of a file with a large header. # This is line 732 of a file with a large header. # This is line 733 of a file with a large header. # This is line 734 of a file with a large header. # This is line 735 of a file with a large header. # This is line 736 of a file with a large header. # This is line 737 of a file with a large header. # This is line 738 of a file with a large header. # This is line 739 of a file with a large header. # This is line 740 of a file with a large header. # This is line 741 of a file with a large header. # This is line 742 of a file with a large header. # This is line 743 of a file with a large header. # This is line 744 of a file with a large header. # This is line 745 of a file with a large header. # This is line 746 of a file with a large header. # This is line 747 of a file with a large header. # This is line 748 of a file with a large header. # This is line 749 of a file with a large header. # This is line 750 of a file with a large header. # This is line 751 of a file with a large header. # This is line 752 of a file with a large header. # This is line 753 of a file with a large header. # This is line 754 of a file with a large header. # This is line 755 of a file with a large header. # This is line 756 of a file with a large header. # This is line 757 of a file with a large header. # This is line 758 of a file with a large header. # This is line 759 of a file with a large header. # This is line 760 of a file with a large header. # This is line 761 of a file with a large header. # This is line 762 of a file with a large header. # This is line 763 of a file with a large header. # This is line 764 of a file with a large header. # This is line 765 of a file with a large header. # This is line 766 of a file with a large header. # This is line 767 of a file with a large header. # This is line 768 of a file with a large header. # This is line 769 of a file with a large header. # This is line 770 of a file with a large header. # This is line 771 of a file with a large header. # This is line 772 of a file with a large header. # This is line 773 of a file with a large header. # This is line 774 of a file with a large header. # This is line 775 of a file with a large header. # This is line 776 of a file with a large header. # This is line 777 of a file with a large header. # This is line 778 of a file with a large header. # This is line 779 of a file with a large header. # This is line 780 of a file with a large header. # This is line 781 of a file with a large header. # This is line 782 of a file with a large header. # This is line 783 of a file with a large header. # This is line 784 of a file with a large header. # This is line 785 of a file with a large header. # This is line 786 of a file with a large header. # This is line 787 of a file with a large header. # This is line 788 of a file with a large header. # This is line 789 of a file with a large header. # This is line 790 of a file with a large header. # This is line 791 of a file with a large header. # This is line 792 of a file with a large header. # This is line 793 of a file with a large header. # This is line 794 of a file with a large header. # This is line 795 of a file with a large header. # This is line 796 of a file with a large header. # This is line 797 of a file with a large header. # This is line 798 of a file with a large header. # This is line 799 of a file with a large header. # This is line 800 of a file with a large header. # This is line 801 of a file with a large header. # This is line 802 of a file with a large header. # This is line 803 of a file with a large header. # This is line 804 of a file with a large header. # This is line 805 of a file with a large header. # This is line 806 of a file with a large header. # This is line 807 of a file with a large header. # This is line 808 of a file with a large header. # This is line 809 of a file with a large header. # This is line 810 of a file with a large header. # This is line 811 of a file with a large header. # This is line 812 of a file with a large header. # This is line 813 of a file with a large header. # This is line 814 of a file with a large header. # This is line 815 of a file with a large header. # This is line 816 of a file with a large header. # This is line 817 of a file with a large header. # This is line 818 of a file with a large header. # This is line 819 of a file with a large header. # This is line 820 of a file with a large header. # This is line 821 of a file with a large header. # This is line 822 of a file with a large header. # This is line 823 of a file with a large header. # This is line 824 of a file with a large header. # This is line 825 of a file with a large header. # This is line 826 of a file with a large header. # This is line 827 of a file with a large header. # This is line 828 of a file with a large header. # This is line 829 of a file with a large header. # This is line 830 of a file with a large header. # This is line 831 of a file with a large header. # This is line 832 of a file with a large header. # This is line 833 of a file with a large header. # This is line 834 of a file with a large header. # This is line 835 of a file with a large header. # This is line 836 of a file with a large header. # This is line 837 of a file with a large header. # This is line 838 of a file with a large header. # This is line 839 of a file with a large header. # This is line 840 of a file with a large header. # This is line 841 of a file with a large header. # This is line 842 of a file with a large header. # This is line 843 of a file with a large header. # This is line 844 of a file with a large header. # This is line 845 of a file with a large header. # This is line 846 of a file with a large header. # This is line 847 of a file with a large header. # This is line 848 of a file with a large header. # This is line 849 of a file with a large header. # This is line 850 of a file with a large header. # This is line 851 of a file with a large header. # This is line 852 of a file with a large header. # This is line 853 of a file with a large header. # This is line 854 of a file with a large header. # This is line 855 of a file with a large header. # This is line 856 of a file with a large header. # This is line 857 of a file with a large header. # This is line 858 of a file with a large header. # This is line 859 of a file with a large header. # This is line 860 of a file with a large header. # This is line 861 of a file with a large header. # This is line 862 of a file with a large header. # This is line 863 of a file with a large header. # This is line 864 of a file with a large header. # This is line 865 of a file with a large header. # This is line 866 of a file with a large header. # This is line 867 of a file with a large header. # This is line 868 of a file with a large header. # This is line 869 of a file with a large header. # This is line 870 of a file with a large header. # This is line 871 of a file with a large header. # This is line 872 of a file with a large header. # This is line 873 of a file with a large header. # This is line 874 of a file with a large header. # This is line 875 of a file with a large header. # This is line 876 of a file with a large header. # This is line 877 of a file with a large header. # This is line 878 of a file with a large header. # This is line 879 of a file with a large header. # This is line 880 of a file with a large header. # This is line 881 of a file with a large header. # This is line 882 of a file with a large header. # This is line 883 of a file with a large header. # This is line 884 of a file with a large header. # This is line 885 of a file with a large header. # This is line 886 of a file with a large header. # This is line 887 of a file with a large header. # This is line 888 of a file with a large header. # This is line 889 of a file with a large header. # This is line 890 of a file with a large header. # This is line 891 of a file with a large header. # This is line 892 of a file with a large header. # This is line 893 of a file with a large header. # This is line 894 of a file with a large header. # This is line 895 of a file with a large header. # This is line 896 of a file with a large header. # This is line 897 of a file with a large header. # This is line 898 of a file with a large header. # This is line 899 of a file with a large header. # This is line 900 of a file with a large header. # This is line 901 of a file with a large header. # This is line 902 of a file with a large header. # This is line 903 of a file with a large header. # This is line 904 of a file with a large header. # This is line 905 of a file with a large header. # This is line 906 of a file with a large header. # This is line 907 of a file with a large header. # This is line 908 of a file with a large header. # This is line 909 of a file with a large header. # This is line 910 of a file with a large header. # This is line 911 of a file with a large header. # This is line 912 of a file with a large header. # This is line 913 of a file with a large header. # This is line 914 of a file with a large header. # This is line 915 of a file with a large header. # This is line 916 of a file with a large header. # This is line 917 of a file with a large header. # This is line 918 of a file with a large header. # This is line 919 of a file with a large header. # This is line 920 of a file with a large header. # This is line 921 of a file with a large header. # This is line 922 of a file with a large header. # This is line 923 of a file with a large header. # This is line 924 of a file with a large header. # This is line 925 of a file with a large header. # This is line 926 of a file with a large header. # This is line 927 of a file with a large header. # This is line 928 of a file with a large header. # This is line 929 of a file with a large header. # This is line 930 of a file with a large header. # This is line 931 of a file with a large header. # This is line 932 of a file with a large header. # This is line 933 of a file with a large header. # This is line 934 of a file with a large header. # This is line 935 of a file with a large header. # This is line 936 of a file with a large header. # This is line 937 of a file with a large header. # This is line 938 of a file with a large header. # This is line 939 of a file with a large header. # This is line 940 of a file with a large header. # This is line 941 of a file with a large header. # This is line 942 of a file with a large header. # This is line 943 of a file with a large header. # This is line 944 of a file with a large header. # This is line 945 of a file with a large header. # This is line 946 of a file with a large header. # This is line 947 of a file with a large header. # This is line 948 of a file with a large header. # This is line 949 of a file with a large header. # This is line 950 of a file with a large header. # This is line 951 of a file with a large header. # This is line 952 of a file with a large header. # This is line 953 of a file with a large header. # This is line 954 of a file with a large header. # This is line 955 of a file with a large header. # This is line 956 of a file with a large header. # This is line 957 of a file with a large header. # This is line 958 of a file with a large header. # This is line 959 of a file with a large header. # This is line 960 of a file with a large header. # This is line 961 of a file with a large header. # This is line 962 of a file with a large header. # This is line 963 of a file with a large header. # This is line 964 of a file with a large header. # This is line 965 of a file with a large header. # This is line 966 of a file with a large header. # This is line 967 of a file with a large header. # This is line 968 of a file with a large header. # This is line 969 of a file with a large header. # This is line 970 of a file with a large header. # This is line 971 of a file with a large header. # This is line 972 of a file with a large header. # This is line 973 of a file with a large header. # This is line 974 of a file with a large header. # This is line 975 of a file with a large header. # This is line 976 of a file with a large header. # This is line 977 of a file with a large header. # This is line 978 of a file with a large header. # This is line 979 of a file with a large header. # This is line 980 of a file with a large header. # This is line 981 of a file with a large header. # This is line 982 of a file with a large header. # This is line 983 of a file with a large header. # This is line 984 of a file with a large header. # This is line 985 of a file with a large header. # This is line 986 of a file with a large header. # This is line 987 of a file with a large header. # This is line 988 of a file with a large header. # This is line 989 of a file with a large header. # This is line 990 of a file with a large header. # This is line 991 of a file with a large header. # This is line 992 of a file with a large header. # This is line 993 of a file with a large header. # This is line 994 of a file with a large header. # This is line 995 of a file with a large header. # This is line 996 of a file with a large header. # This is line 997 of a file with a large header. # This is line 998 of a file with a large header. # This is line 999 of a file with a large header. # This is line 1000 of a file with a large header. # This is line 1001 of a file with a large header. # This is line 1002 of a file with a large header. # This is line 1003 of a file with a large header. # This is line 1004 of a file with a large header. # This is line 1005 of a file with a large header. # This is line 1006 of a file with a large header. # This is line 1007 of a file with a large header. # This is line 1008 of a file with a large header. # This is line 1009 of a file with a large header. # This is line 1010 of a file with a large header. # This is line 1011 of a file with a large header. # This is line 1012 of a file with a large header. # This is line 1013 of a file with a large header. # This is line 1014 of a file with a large header. # This is line 1015 of a file with a large header. # This is line 1016 of a file with a large header. # This is line 1017 of a file with a large header. # This is line 1018 of a file with a large header. # This is line 1019 of a file with a large header. # This is line 1020 of a file with a large header. # This is line 1021 of a file with a large header. # This is line 1022 of a file with a large header. # This is line 1023 of a file with a large header. # This is line 1024 of a file with a large header. # This is line 1025 of a file with a large header. # This is line 1026 of a file with a large header. # This is line 1027 of a file with a large header. # This is line 1028 of a file with a large header. # This is line 1029 of a file with a large header. # This is line 1030 of a file with a large header. # This is line 1031 of a file with a large header. # This is line 1032 of a file with a large header. # This is line 1033 of a file with a large header. # This is line 1034 of a file with a large header. # This is line 1035 of a file with a large header. # This is line 1036 of a file with a large header. # This is line 1037 of a file with a large header. # This is line 1038 of a file with a large header. # This is line 1039 of a file with a large header. # This is line 1040 of a file with a large header. # This is line 1041 of a file with a large header. # This is line 1042 of a file with a large header. # This is line 1043 of a file with a large header. # This is line 1044 of a file with a large header. # This is line 1045 of a file with a large header. # This is line 1046 of a file with a large header. # This is line 1047 of a file with a large header. # This is line 1048 of a file with a large header. # This is line 1049 of a file with a large header. # This is line 1050 of a file with a large header. # This is line 1051 of a file with a large header. # This is line 1052 of a file with a large header. # This is line 1053 of a file with a large header. # This is line 1054 of a file with a large header. # This is line 1055 of a file with a large header. # This is line 1056 of a file with a large header. # This is line 1057 of a file with a large header. # This is line 1058 of a file with a large header. # This is line 1059 of a file with a large header. # This is line 1060 of a file with a large header. # This is line 1061 of a file with a large header. # This is line 1062 of a file with a large header. # This is line 1063 of a file with a large header. # This is line 1064 of a file with a large header. # This is line 1065 of a file with a large header. # This is line 1066 of a file with a large header. # This is line 1067 of a file with a large header. # This is line 1068 of a file with a large header. # This is line 1069 of a file with a large header. # This is line 1070 of a file with a large header. # This is line 1071 of a file with a large header. # This is line 1072 of a file with a large header. # This is line 1073 of a file with a large header. # This is line 1074 of a file with a large header. # This is line 1075 of a file with a large header. # This is line 1076 of a file with a large header. # This is line 1077 of a file with a large header. # This is line 1078 of a file with a large header. # This is line 1079 of a file with a large header. # This is line 1080 of a file with a large header. # This is line 1081 of a file with a large header. # This is line 1082 of a file with a large header. # This is line 1083 of a file with a large header. # This is line 1084 of a file with a large header. # This is line 1085 of a file with a large header. # This is line 1086 of a file with a large header. # This is line 1087 of a file with a large header. # This is line 1088 of a file with a large header. # This is line 1089 of a file with a large header. # This is line 1090 of a file with a large header. # This is line 1091 of a file with a large header. # This is line 1092 of a file with a large header. # This is line 1093 of a file with a large header. # This is line 1094 of a file with a large header. # This is line 1095 of a file with a large header. # This is line 1096 of a file with a large header. # This is line 1097 of a file with a large header. # This is line 1098 of a file with a large header. # This is line 1099 of a file with a large header. # This is line 1100 of a file with a large header. # This is line 1101 of a file with a large header. # This is line 1102 of a file with a large header. # This is line 1103 of a file with a large header. # This is line 1104 of a file with a large header. # This is line 1105 of a file with a large header. # This is line 1106 of a file with a large header. # This is line 1107 of a file with a large header. # This is line 1108 of a file with a large header. # This is line 1109 of a file with a large header. # This is line 1110 of a file with a large header. # This is line 1111 of a file with a large header. # This is line 1112 of a file with a large header. # This is line 1113 of a file with a large header. # This is line 1114 of a file with a large header. # This is line 1115 of a file with a large header. # This is line 1116 of a file with a large header. # This is line 1117 of a file with a large header. # This is line 1118 of a file with a large header. # This is line 1119 of a file with a large header. # This is line 1120 of a file with a large header. # This is line 1121 of a file with a large header. # This is line 1122 of a file with a large header. # This is line 1123 of a file with a large header. # This is line 1124 of a file with a large header. # This is line 1125 of a file with a large header. # This is line 1126 of a file with a large header. # This is line 1127 of a file with a large header. # This is line 1128 of a file with a large header. # This is line 1129 of a file with a large header. # This is line 1130 of a file with a large header. # This is line 1131 of a file with a large header. # This is line 1132 of a file with a large header. # This is line 1133 of a file with a large header. # This is line 1134 of a file with a large header. # This is line 1135 of a file with a large header. # This is line 1136 of a file with a large header. # This is line 1137 of a file with a large header. # This is line 1138 of a file with a large header. # This is line 1139 of a file with a large header. # This is line 1140 of a file with a large header. # This is line 1141 of a file with a large header. # This is line 1142 of a file with a large header. # This is line 1143 of a file with a large header. # This is line 1144 of a file with a large header. # This is line 1145 of a file with a large header. # This is line 1146 of a file with a large header. # This is line 1147 of a file with a large header. # This is line 1148 of a file with a large header. # This is line 1149 of a file with a large header. # This is line 1150 of a file with a large header. # This is line 1151 of a file with a large header. # This is line 1152 of a file with a large header. # This is line 1153 of a file with a large header. # This is line 1154 of a file with a large header. # This is line 1155 of a file with a large header. # This is line 1156 of a file with a large header. # This is line 1157 of a file with a large header. # This is line 1158 of a file with a large header. # This is line 1159 of a file with a large header. # This is line 1160 of a file with a large header. # This is line 1161 of a file with a large header. # This is line 1162 of a file with a large header. # This is line 1163 of a file with a large header. # This is line 1164 of a file with a large header. # This is line 1165 of a file with a large header. # This is line 1166 of a file with a large header. # This is line 1167 of a file with a large header. # This is line 1168 of a file with a large header. # This is line 1169 of a file with a large header. # This is line 1170 of a file with a large header. # This is line 1171 of a file with a large header. # This is line 1172 of a file with a large header. # This is line 1173 of a file with a large header. # This is line 1174 of a file with a large header. # This is line 1175 of a file with a large header. # This is line 1176 of a file with a large header. # This is line 1177 of a file with a large header. # This is line 1178 of a file with a large header. # This is line 1179 of a file with a large header. # This is line 1180 of a file with a large header. # This is line 1181 of a file with a large header. # This is line 1182 of a file with a large header. # This is line 1183 of a file with a large header. # This is line 1184 of a file with a large header. # This is line 1185 of a file with a large header. # This is line 1186 of a file with a large header. # This is line 1187 of a file with a large header. # This is line 1188 of a file with a large header. # This is line 1189 of a file with a large header. # This is line 1190 of a file with a large header. # This is line 1191 of a file with a large header. # This is line 1192 of a file with a large header. # This is line 1193 of a file with a large header. # This is line 1194 of a file with a large header. # This is line 1195 of a file with a large header. # This is line 1196 of a file with a large header. # This is line 1197 of a file with a large header. # This is line 1198 of a file with a large header. # This is line 1199 of a file with a large header. # This is line 1200 of a file with a large header. # This is line 1201 of a file with a large header. # This is line 1202 of a file with a large header. # This is line 1203 of a file with a large header. # This is line 1204 of a file with a large header. # This is line 1205 of a file with a large header. # This is line 1206 of a file with a large header. # This is line 1207 of a file with a large header. # This is line 1208 of a file with a large header. # This is line 1209 of a file with a large header. # This is line 1210 of a file with a large header. # This is line 1211 of a file with a large header. # This is line 1212 of a file with a large header. # This is line 1213 of a file with a large header. # This is line 1214 of a file with a large header. # This is line 1215 of a file with a large header. # This is line 1216 of a file with a large header. # This is line 1217 of a file with a large header. # This is line 1218 of a file with a large header. # This is line 1219 of a file with a large header. # This is line 1220 of a file with a large header. # This is line 1221 of a file with a large header. # This is line 1222 of a file with a large header. # This is line 1223 of a file with a large header. # This is line 1224 of a file with a large header. # This is line 1225 of a file with a large header. # This is line 1226 of a file with a large header. # This is line 1227 of a file with a large header. # This is line 1228 of a file with a large header. # This is line 1229 of a file with a large header. # This is line 1230 of a file with a large header. # This is line 1231 of a file with a large header. # This is line 1232 of a file with a large header. # This is line 1233 of a file with a large header. # This is line 1234 of a file with a large header. # This is line 1235 of a file with a large header. # This is line 1236 of a file with a large header. # This is line 1237 of a file with a large header. # This is line 1238 of a file with a large header. # This is line 1239 of a file with a large header. # This is line 1240 of a file with a large header. # This is line 1241 of a file with a large header. # This is line 1242 of a file with a large header. # This is line 1243 of a file with a large header. # This is line 1244 of a file with a large header. # This is line 1245 of a file with a large header. # This is line 1246 of a file with a large header. # This is line 1247 of a file with a large header. # This is line 1248 of a file with a large header. # This is line 1249 of a file with a large header. # This is line 1250 of a file with a large header. # This is line 1251 of a file with a large header. # This is line 1252 of a file with a large header. # This is line 1253 of a file with a large header. # This is line 1254 of a file with a large header. # This is line 1255 of a file with a large header. # This is line 1256 of a file with a large header. # This is line 1257 of a file with a large header. # This is line 1258 of a file with a large header. # This is line 1259 of a file with a large header. # This is line 1260 of a file with a large header. # This is line 1261 of a file with a large header. # This is line 1262 of a file with a large header. # This is line 1263 of a file with a large header. # This is line 1264 of a file with a large header. # This is line 1265 of a file with a large header. # This is line 1266 of a file with a large header. # This is line 1267 of a file with a large header. # This is line 1268 of a file with a large header. # This is line 1269 of a file with a large header. # This is line 1270 of a file with a large header. # This is line 1271 of a file with a large header. # This is line 1272 of a file with a large header. # This is line 1273 of a file with a large header. # This is line 1274 of a file with a large header. # This is line 1275 of a file with a large header. # This is line 1276 of a file with a large header. # This is line 1277 of a file with a large header. # This is line 1278 of a file with a large header. # This is line 1279 of a file with a large header. # This is line 1280 of a file with a large header. # This is line 1281 of a file with a large header. # This is line 1282 of a file with a large header. # This is line 1283 of a file with a large header. # This is line 1284 of a file with a large header. # This is line 1285 of a file with a large header. # This is line 1286 of a file with a large header. # This is line 1287 of a file with a large header. # This is line 1288 of a file with a large header. # This is line 1289 of a file with a large header. # This is line 1290 of a file with a large header. # This is line 1291 of a file with a large header. # This is line 1292 of a file with a large header. # This is line 1293 of a file with a large header. # This is line 1294 of a file with a large header. # This is line 1295 of a file with a large header. # This is line 1296 of a file with a large header. # This is line 1297 of a file with a large header. # This is line 1298 of a file with a large header. # This is line 1299 of a file with a large header. # This is line 1300 of a file with a large header. # This is line 1301 of a file with a large header. # This is line 1302 of a file with a large header. # This is line 1303 of a file with a large header. # This is line 1304 of a file with a large header. # This is line 1305 of a file with a large header. # This is line 1306 of a file with a large header. # This is line 1307 of a file with a large header. # This is line 1308 of a file with a large header. # This is line 1309 of a file with a large header. # This is line 1310 of a file with a large header. # This is line 1311 of a file with a large header. # This is line 1312 of a file with a large header. # This is line 1313 of a file with a large header. # This is line 1314 of a file with a large header. # This is line 1315 of a file with a large header. # This is line 1316 of a file with a large header. # This is line 1317 of a file with a large header. # This is line 1318 of a file with a large header. # This is line 1319 of a file with a large header. # This is line 1320 of a file with a large header. # This is line 1321 of a file with a large header. # This is line 1322 of a file with a large header. # This is line 1323 of a file with a large header. # This is line 1324 of a file with a large header. # This is line 1325 of a file with a large header. # This is line 1326 of a file with a large header. # This is line 1327 of a file with a large header. # This is line 1328 of a file with a large header. # This is line 1329 of a file with a large header. # This is line 1330 of a file with a large header. # This is line 1331 of a file with a large header. # This is line 1332 of a file with a large header. # This is line 1333 of a file with a large header. # This is line 1334 of a file with a large header. # This is line 1335 of a file with a large header. # This is line 1336 of a file with a large header. # This is line 1337 of a file with a large header. # This is line 1338 of a file with a large header. # This is line 1339 of a file with a large header. # This is line 1340 of a file with a large header. # This is line 1341 of a file with a large header. # This is line 1342 of a file with a large header. # This is line 1343 of a file with a large header. # This is line 1344 of a file with a large header. # This is line 1345 of a file with a large header. # This is line 1346 of a file with a large header. # This is line 1347 of a file with a large header. # This is line 1348 of a file with a large header. # This is line 1349 of a file with a large header. # This is line 1350 of a file with a large header. # This is line 1351 of a file with a large header. # This is line 1352 of a file with a large header. # This is line 1353 of a file with a large header. # This is line 1354 of a file with a large header. # This is line 1355 of a file with a large header. # This is line 1356 of a file with a large header. # This is line 1357 of a file with a large header. # This is line 1358 of a file with a large header. # This is line 1359 of a file with a large header. # This is line 1360 of a file with a large header. # This is line 1361 of a file with a large header. # This is line 1362 of a file with a large header. # This is line 1363 of a file with a large header. # This is line 1364 of a file with a large header. # This is line 1365 of a file with a large header. # This is line 1366 of a file with a large header. # This is line 1367 of a file with a large header. # This is line 1368 of a file with a large header. # This is line 1369 of a file with a large header. # This is line 1370 of a file with a large header. # This is line 1371 of a file with a large header. # This is line 1372 of a file with a large header. # This is line 1373 of a file with a large header. # This is line 1374 of a file with a large header. # This is line 1375 of a file with a large header. # This is line 1376 of a file with a large header. # This is line 1377 of a file with a large header. # This is line 1378 of a file with a large header. # This is line 1379 of a file with a large header. # This is line 1380 of a file with a large header. # This is line 1381 of a file with a large header. # This is line 1382 of a file with a large header. # This is line 1383 of a file with a large header. # This is line 1384 of a file with a large header. # This is line 1385 of a file with a large header. # This is line 1386 of a file with a large header. # This is line 1387 of a file with a large header. # This is line 1388 of a file with a large header. # This is line 1389 of a file with a large header. # This is line 1390 of a file with a large header. # This is line 1391 of a file with a large header. # This is line 1392 of a file with a large header. # This is line 1393 of a file with a large header. # This is line 1394 of a file with a large header. # This is line 1395 of a file with a large header. # This is line 1396 of a file with a large header. # This is line 1397 of a file with a large header. # This is line 1398 of a file with a large header. # This is line 1399 of a file with a large header. # This is line 1400 of a file with a large header. # This is line 1401 of a file with a large header. # This is line 1402 of a file with a large header. # This is line 1403 of a file with a large header. # This is line 1404 of a file with a large header. # This is line 1405 of a file with a large header. # This is line 1406 of a file with a large header. # This is line 1407 of a file with a large header. # This is line 1408 of a file with a large header. # This is line 1409 of a file with a large header. # This is line 1410 of a file with a large header. # This is line 1411 of a file with a large header. # This is line 1412 of a file with a large header. # This is line 1413 of a file with a large header. # This is line 1414 of a file with a large header. # This is line 1415 of a file with a large header. # This is line 1416 of a file with a large header. # This is line 1417 of a file with a large header. # This is line 1418 of a file with a large header. # This is line 1419 of a file with a large header. # This is line 1420 of a file with a large header. # This is line 1421 of a file with a large header. # This is line 1422 of a file with a large header. # This is line 1423 of a file with a large header. # This is line 1424 of a file with a large header. # This is line 1425 of a file with a large header. # This is line 1426 of a file with a large header. # This is line 1427 of a file with a large header. # This is line 1428 of a file with a large header. # This is line 1429 of a file with a large header. # This is line 1430 of a file with a large header. # This is line 1431 of a file with a large header. # This is line 1432 of a file with a large header. # This is line 1433 of a file with a large header. # This is line 1434 of a file with a large header. # This is line 1435 of a file with a large header. # This is line 1436 of a file with a large header. # This is line 1437 of a file with a large header. # This is line 1438 of a file with a large header. # This is line 1439 of a file with a large header. # This is line 1440 of a file with a large header. # This is line 1441 of a file with a large header. # This is line 1442 of a file with a large header. # This is line 1443 of a file with a large header. # This is line 1444 of a file with a large header. # This is line 1445 of a file with a large header. # This is line 1446 of a file with a large header. # This is line 1447 of a file with a large header. # This is line 1448 of a file with a large header. # This is line 1449 of a file with a large header. # This is line 1450 of a file with a large header. # This is line 1451 of a file with a large header. # This is line 1452 of a file with a large header. # This is line 1453 of a file with a large header. # This is line 1454 of a file with a large header. # This is line 1455 of a file with a large header. # This is line 1456 of a file with a large header. # This is line 1457 of a file with a large header. # This is line 1458 of a file with a large header. # This is line 1459 of a file with a large header. # This is line 1460 of a file with a large header. # This is line 1461 of a file with a large header. # This is line 1462 of a file with a large header. # This is line 1463 of a file with a large header. # This is line 1464 of a file with a large header. # This is line 1465 of a file with a large header. # This is line 1466 of a file with a large header. # This is line 1467 of a file with a large header. # This is line 1468 of a file with a large header. # This is line 1469 of a file with a large header. # This is line 1470 of a file with a large header. # This is line 1471 of a file with a large header. # This is line 1472 of a file with a large header. # This is line 1473 of a file with a large header. # This is line 1474 of a file with a large header. # This is line 1475 of a file with a large header. # This is line 1476 of a file with a large header. # This is line 1477 of a file with a large header. # This is line 1478 of a file with a large header. # This is line 1479 of a file with a large header. # This is line 1480 of a file with a large header. # This is line 1481 of a file with a large header. # This is line 1482 of a file with a large header. # This is line 1483 of a file with a large header. # This is line 1484 of a file with a large header. # This is line 1485 of a file with a large header. # This is line 1486 of a file with a large header. # This is line 1487 of a file with a large header. # This is line 1488 of a file with a large header. # This is line 1489 of a file with a large header. # This is line 1490 of a file with a large header. # This is line 1491 of a file with a large header. # This is line 1492 of a file with a large header. # This is line 1493 of a file with a large header. # This is line 1494 of a file with a large header. # This is line 1495 of a file with a large header. # This is line 1496 of a file with a large header. # This is line 1497 of a file with a large header. # This is line 1498 of a file with a large header. # This is line 1499 of a file with a large header. # This is line 1500 of a file with a large header. # This is line 1501 of a file with a large header. # This is line 1502 of a file with a large header. # This is line 1503 of a file with a large header. # This is line 1504 of a file with a large header. # This is line 1505 of a file with a large header. # This is line 1506 of a file with a large header. # This is line 1507 of a file with a large header. # This is line 1508 of a file with a large header. # This is line 1509 of a file with a large header. # This is line 1510 of a file with a large header. # This is line 1511 of a file with a large header. # This is line 1512 of a file with a large header. # This is line 1513 of a file with a large header. # This is line 1514 of a file with a large header. # This is line 1515 of a file with a large header. # This is line 1516 of a file with a large header. # This is line 1517 of a file with a large header. # This is line 1518 of a file with a large header. # This is line 1519 of a file with a large header. # This is line 1520 of a file with a large header. # This is line 1521 of a file with a large header. # This is line 1522 of a file with a large header. # This is line 1523 of a file with a large header. # This is line 1524 of a file with a large header. # This is line 1525 of a file with a large header. # This is line 1526 of a file with a large header. # This is line 1527 of a file with a large header. # This is line 1528 of a file with a large header. # This is line 1529 of a file with a large header. # This is line 1530 of a file with a large header. # This is line 1531 of a file with a large header. # This is line 1532 of a file with a large header. # This is line 1533 of a file with a large header. # This is line 1534 of a file with a large header. # This is line 1535 of a file with a large header. # This is line 1536 of a file with a large header. # This is line 1537 of a file with a large header. # This is line 1538 of a file with a large header. # This is line 1539 of a file with a large header. # This is line 1540 of a file with a large header. # This is line 1541 of a file with a large header. # This is line 1542 of a file with a large header. # This is line 1543 of a file with a large header. # This is line 1544 of a file with a large header. # This is line 1545 of a file with a large header. # This is line 1546 of a file with a large header. # This is line 1547 of a file with a large header. # This is line 1548 of a file with a large header. # This is line 1549 of a file with a large header. # This is line 1550 of a file with a large header. # This is line 1551 of a file with a large header. # This is line 1552 of a file with a large header. # This is line 1553 of a file with a large header. # This is line 1554 of a file with a large header. # This is line 1555 of a file with a large header. # This is line 1556 of a file with a large header. # This is line 1557 of a file with a large header. # This is line 1558 of a file with a large header. # This is line 1559 of a file with a large header. # This is line 1560 of a file with a large header. # This is line 1561 of a file with a large header. # This is line 1562 of a file with a large header. # This is line 1563 of a file with a large header. # This is line 1564 of a file with a large header. # This is line 1565 of a file with a large header. # This is line 1566 of a file with a large header. # This is line 1567 of a file with a large header. # This is line 1568 of a file with a large header. # This is line 1569 of a file with a large header. # This is line 1570 of a file with a large header. # This is line 1571 of a file with a large header. # This is line 1572 of a file with a large header. # This is line 1573 of a file with a large header. # This is line 1574 of a file with a large header. # This is line 1575 of a file with a large header. # This is line 1576 of a file with a large header. # This is line 1577 of a file with a large header. # This is line 1578 of a file with a large header. # This is line 1579 of a file with a large header. # This is line 1580 of a file with a large header. # This is line 1581 of a file with a large header. # This is line 1582 of a file with a large header. # This is line 1583 of a file with a large header. # This is line 1584 of a file with a large header. # This is line 1585 of a file with a large header. # This is line 1586 of a file with a large header. # This is line 1587 of a file with a large header. # This is line 1588 of a file with a large header. # This is line 1589 of a file with a large header. # This is line 1590 of a file with a large header. # This is line 1591 of a file with a large header. # This is line 1592 of a file with a large header. # This is line 1593 of a file with a large header. # This is line 1594 of a file with a large header. # This is line 1595 of a file with a large header. # This is line 1596 of a file with a large header. # This is line 1597 of a file with a large header. # This is line 1598 of a file with a large header. # This is line 1599 of a file with a large header. # This is line 1600 of a file with a large header. # This is line 1601 of a file with a large header. # This is line 1602 of a file with a large header. # This is line 1603 of a file with a large header. # This is line 1604 of a file with a large header. # This is line 1605 of a file with a large header. # This is line 1606 of a file with a large header. # This is line 1607 of a file with a large header. # This is line 1608 of a file with a large header. # This is line 1609 of a file with a large header. # This is line 1610 of a file with a large header. # This is line 1611 of a file with a large header. # This is line 1612 of a file with a large header. # This is line 1613 of a file with a large header. # This is line 1614 of a file with a large header. # This is line 1615 of a file with a large header. # This is line 1616 of a file with a large header. # This is line 1617 of a file with a large header. # This is line 1618 of a file with a large header. # This is line 1619 of a file with a large header. # This is line 1620 of a file with a large header. # This is line 1621 of a file with a large header. # This is line 1622 of a file with a large header. # This is line 1623 of a file with a large header. # This is line 1624 of a file with a large header. # This is line 1625 of a file with a large header. # This is line 1626 of a file with a large header. # This is line 1627 of a file with a large header. # This is line 1628 of a file with a large header. # This is line 1629 of a file with a large header. # This is line 1630 of a file with a large header. # This is line 1631 of a file with a large header. # This is line 1632 of a file with a large header. # This is line 1633 of a file with a large header. # This is line 1634 of a file with a large header. # This is line 1635 of a file with a large header. # This is line 1636 of a file with a large header. # This is line 1637 of a file with a large header. # This is line 1638 of a file with a large header. # This is line 1639 of a file with a large header. # This is line 1640 of a file with a large header. # This is line 1641 of a file with a large header. # This is line 1642 of a file with a large header. # This is line 1643 of a file with a large header. # This is line 1644 of a file with a large header. # This is line 1645 of a file with a large header. # This is line 1646 of a file with a large header. # This is line 1647 of a file with a large header. # This is line 1648 of a file with a large header. # This is line 1649 of a file with a large header. # This is line 1650 of a file with a large header. # This is line 1651 of a file with a large header. # This is line 1652 of a file with a large header. # This is line 1653 of a file with a large header. # This is line 1654 of a file with a large header. # This is line 1655 of a file with a large header. # This is line 1656 of a file with a large header. # This is line 1657 of a file with a large header. # This is line 1658 of a file with a large header. # This is line 1659 of a file with a large header. # This is line 1660 of a file with a large header. # This is line 1661 of a file with a large header. # This is line 1662 of a file with a large header. # This is line 1663 of a file with a large header. # This is line 1664 of a file with a large header. # This is line 1665 of a file with a large header. # This is line 1666 of a file with a large header. # This is line 1667 of a file with a large header. # This is line 1668 of a file with a large header. # This is line 1669 of a file with a large header. # This is line 1670 of a file with a large header. # This is line 1671 of a file with a large header. # This is line 1672 of a file with a large header. # This is line 1673 of a file with a large header. # This is line 1674 of a file with a large header. # This is line 1675 of a file with a large header. # This is line 1676 of a file with a large header. # This is line 1677 of a file with a large header. # This is line 1678 of a file with a large header. # This is line 1679 of a file with a large header. # This is line 1680 of a file with a large header. # This is line 1681 of a file with a large header. # This is line 1682 of a file with a large header. # This is line 1683 of a file with a large header. # This is line 1684 of a file with a large header. # This is line 1685 of a file with a large header. # This is line 1686 of a file with a large header. # This is line 1687 of a file with a large header. # This is line 1688 of a file with a large header. # This is line 1689 of a file with a large header. # This is line 1690 of a file with a large header. # This is line 1691 of a file with a large header. # This is line 1692 of a file with a large header. # This is line 1693 of a file with a large header. # This is line 1694 of a file with a large header. # This is line 1695 of a file with a large header. # This is line 1696 of a file with a large header. # This is line 1697 of a file with a large header. # This is line 1698 of a file with a large header. # This is line 1699 of a file with a large header. # This is line 1700 of a file with a large header. # This is line 1701 of a file with a large header. # This is line 1702 of a file with a large header. # This is line 1703 of a file with a large header. # This is line 1704 of a file with a large header. # This is line 1705 of a file with a large header. # This is line 1706 of a file with a large header. # This is line 1707 of a file with a large header. # This is line 1708 of a file with a large header. # This is line 1709 of a file with a large header. # This is line 1710 of a file with a large header. # This is line 1711 of a file with a large header. # This is line 1712 of a file with a large header. # This is line 1713 of a file with a large header. # This is line 1714 of a file with a large header. # This is line 1715 of a file with a large header. # This is line 1716 of a file with a large header. # This is line 1717 of a file with a large header. # This is line 1718 of a file with a large header. # This is line 1719 of a file with a large header. # This is line 1720 of a file with a large header. # This is line 1721 of a file with a large header. # This is line 1722 of a file with a large header. # This is line 1723 of a file with a large header. # This is line 1724 of a file with a large header. # This is line 1725 of a file with a large header. # This is line 1726 of a file with a large header. # This is line 1727 of a file with a large header. # This is line 1728 of a file with a large header. # This is line 1729 of a file with a large header. # This is line 1730 of a file with a large header. # This is line 1731 of a file with a large header. # This is line 1732 of a file with a large header. # This is line 1733 of a file with a large header. # This is line 1734 of a file with a large header. # This is line 1735 of a file with a large header. # This is line 1736 of a file with a large header. # This is line 1737 of a file with a large header. # This is line 1738 of a file with a large header. # This is line 1739 of a file with a large header. # This is line 1740 of a file with a large header. # This is line 1741 of a file with a large header. # This is line 1742 of a file with a large header. # This is line 1743 of a file with a large header. # This is line 1744 of a file with a large header. # This is line 1745 of a file with a large header. # This is line 1746 of a file with a large header. # This is line 1747 of a file with a large header. # This is line 1748 of a file with a large header. # This is line 1749 of a file with a large header. # This is line 1750 of a file with a large header. # This is line 1751 of a file with a large header. # This is line 1752 of a file with a large header. # This is line 1753 of a file with a large header. # This is line 1754 of a file with a large header. # This is line 1755 of a file with a large header. # This is line 1756 of a file with a large header. # This is line 1757 of a file with a large header. # This is line 1758 of a file with a large header. # This is line 1759 of a file with a large header. # This is line 1760 of a file with a large header. # This is line 1761 of a file with a large header. # This is line 1762 of a file with a large header. # This is line 1763 of a file with a large header. # This is line 1764 of a file with a large header. # This is line 1765 of a file with a large header. # This is line 1766 of a file with a large header. # This is line 1767 of a file with a large header. # This is line 1768 of a file with a large header. # This is line 1769 of a file with a large header. # This is line 1770 of a file with a large header. # This is line 1771 of a file with a large header. # This is line 1772 of a file with a large header. # This is line 1773 of a file with a large header. # This is line 1774 of a file with a large header. # This is line 1775 of a file with a large header. # This is line 1776 of a file with a large header. # This is line 1777 of a file with a large header. # This is line 1778 of a file with a large header. # This is line 1779 of a file with a large header. # This is line 1780 of a file with a large header. # This is line 1781 of a file with a large header. # This is line 1782 of a file with a large header. # This is line 1783 of a file with a large header. # This is line 1784 of a file with a large header. # This is line 1785 of a file with a large header. # This is line 1786 of a file with a large header. # This is line 1787 of a file with a large header. # This is line 1788 of a file with a large header. # This is line 1789 of a file with a large header. # This is line 1790 of a file with a large header. # This is line 1791 of a file with a large header. # This is line 1792 of a file with a large header. # This is line 1793 of a file with a large header. # This is line 1794 of a file with a large header. # This is line 1795 of a file with a large header. # This is line 1796 of a file with a large header. # This is line 1797 of a file with a large header. # This is line 1798 of a file with a large header. # This is line 1799 of a file with a large header. # This is line 1800 of a file with a large header. # This is line 1801 of a file with a large header. # This is line 1802 of a file with a large header. # This is line 1803 of a file with a large header. # This is line 1804 of a file with a large header. # This is line 1805 of a file with a large header. # This is line 1806 of a file with a large header. # This is line 1807 of a file with a large header. # This is line 1808 of a file with a large header. # This is line 1809 of a file with a large header. # This is line 1810 of a file with a large header. # This is line 1811 of a file with a large header. # This is line 1812 of a file with a large header. # This is line 1813 of a file with a large header. # This is line 1814 of a file with a large header. # This is line 1815 of a file with a large header. # This is line 1816 of a file with a large header. # This is line 1817 of a file with a large header. # This is line 1818 of a file with a large header. # This is line 1819 of a file with a large header. # This is line 1820 of a file with a large header. # This is line 1821 of a file with a large header. # This is line 1822 of a file with a large header. # This is line 1823 of a file with a large header. # This is line 1824 of a file with a large header. # This is line 1825 of a file with a large header. # This is line 1826 of a file with a large header. # This is line 1827 of a file with a large header. # This is line 1828 of a file with a large header. # This is line 1829 of a file with a large header. # This is line 1830 of a file with a large header. # This is line 1831 of a file with a large header. # This is line 1832 of a file with a large header. # This is line 1833 of a file with a large header. # This is line 1834 of a file with a large header. # This is line 1835 of a file with a large header. # This is line 1836 of a file with a large header. # This is line 1837 of a file with a large header. # This is line 1838 of a file with a large header. # This is line 1839 of a file with a large header. # This is line 1840 of a file with a large header. # This is line 1841 of a file with a large header. # This is line 1842 of a file with a large header. # This is line 1843 of a file with a large header. # This is line 1844 of a file with a large header. # This is line 1845 of a file with a large header. # This is line 1846 of a file with a large header. # This is line 1847 of a file with a large header. # This is line 1848 of a file with a large header. # This is line 1849 of a file with a large header. # This is line 1850 of a file with a large header. # This is line 1851 of a file with a large header. # This is line 1852 of a file with a large header. # This is line 1853 of a file with a large header. # This is line 1854 of a file with a large header. # This is line 1855 of a file with a large header. # This is line 1856 of a file with a large header. # This is line 1857 of a file with a large header. # This is line 1858 of a file with a large header. # This is line 1859 of a file with a large header. # This is line 1860 of a file with a large header. # This is line 1861 of a file with a large header. # This is line 1862 of a file with a large header. # This is line 1863 of a file with a large header. # This is line 1864 of a file with a large header. # This is line 1865 of a file with a large header. # This is line 1866 of a file with a large header. # This is line 1867 of a file with a large header. # This is line 1868 of a file with a large header. # This is line 1869 of a file with a large header. # This is line 1870 of a file with a large header. # This is line 1871 of a file with a large header. # This is line 1872 of a file with a large header. # This is line 1873 of a file with a large header. # This is line 1874 of a file with a large header. # This is line 1875 of a file with a large header. # This is line 1876 of a file with a large header. # This is line 1877 of a file with a large header. # This is line 1878 of a file with a large header. # This is line 1879 of a file with a large header. # This is line 1880 of a file with a large header. # This is line 1881 of a file with a large header. # This is line 1882 of a file with a large header. # This is line 1883 of a file with a large header. # This is line 1884 of a file with a large header. # This is line 1885 of a file with a large header. # This is line 1886 of a file with a large header. # This is line 1887 of a file with a large header. # This is line 1888 of a file with a large header. # This is line 1889 of a file with a large header. # This is line 1890 of a file with a large header. # This is line 1891 of a file with a large header. # This is line 1892 of a file with a large header. # This is line 1893 of a file with a large header. # This is line 1894 of a file with a large header. # This is line 1895 of a file with a large header. # This is line 1896 of a file with a large header. # This is line 1897 of a file with a large header. # This is line 1898 of a file with a large header. # This is line 1899 of a file with a large header. # This is line 1900 of a file with a large header. # This is line 1901 of a file with a large header. # This is line 1902 of a file with a large header. # This is line 1903 of a file with a large header. # This is line 1904 of a file with a large header. # This is line 1905 of a file with a large header. # This is line 1906 of a file with a large header. # This is line 1907 of a file with a large header. # This is line 1908 of a file with a large header. # This is line 1909 of a file with a large header. # This is line 1910 of a file with a large header. # This is line 1911 of a file with a large header. # This is line 1912 of a file with a large header. # This is line 1913 of a file with a large header. # This is line 1914 of a file with a large header. # This is line 1915 of a file with a large header. # This is line 1916 of a file with a large header. # This is line 1917 of a file with a large header. # This is line 1918 of a file with a large header. # This is line 1919 of a file with a large header. # This is line 1920 of a file with a large header. # This is line 1921 of a file with a large header. # This is line 1922 of a file with a large header. # This is line 1923 of a file with a large header. # This is line 1924 of a file with a large header. # This is line 1925 of a file with a large header. # This is line 1926 of a file with a large header. # This is line 1927 of a file with a large header. # This is line 1928 of a file with a large header. # This is line 1929 of a file with a large header. # This is line 1930 of a file with a large header. # This is line 1931 of a file with a large header. # This is line 1932 of a file with a large header. # This is line 1933 of a file with a large header. # This is line 1934 of a file with a large header. # This is line 1935 of a file with a large header. # This is line 1936 of a file with a large header. # This is line 1937 of a file with a large header. # This is line 1938 of a file with a large header. # This is line 1939 of a file with a large header. # This is line 1940 of a file with a large header. # This is line 1941 of a file with a large header. # This is line 1942 of a file with a large header. # This is line 1943 of a file with a large header. # This is line 1944 of a file with a large header. # This is line 1945 of a file with a large header. # This is line 1946 of a file with a large header. # This is line 1947 of a file with a large header. # This is line 1948 of a file with a large header. # This is line 1949 of a file with a large header. # This is line 1950 of a file with a large header. # This is line 1951 of a file with a large header. # This is line 1952 of a file with a large header. # This is line 1953 of a file with a large header. # This is line 1954 of a file with a large header. # This is line 1955 of a file with a large header. # This is line 1956 of a file with a large header. # This is line 1957 of a file with a large header. # This is line 1958 of a file with a large header. # This is line 1959 of a file with a large header. # This is line 1960 of a file with a large header. # This is line 1961 of a file with a large header. # This is line 1962 of a file with a large header. # This is line 1963 of a file with a large header. # This is line 1964 of a file with a large header. # This is line 1965 of a file with a large header. # This is line 1966 of a file with a large header. # This is line 1967 of a file with a large header. # This is line 1968 of a file with a large header. # This is line 1969 of a file with a large header. # This is line 1970 of a file with a large header. # This is line 1971 of a file with a large header. # This is line 1972 of a file with a large header. # This is line 1973 of a file with a large header. # This is line 1974 of a file with a large header. # This is line 1975 of a file with a large header. # This is line 1976 of a file with a large header. # This is line 1977 of a file with a large header. # This is line 1978 of a file with a large header. # This is line 1979 of a file with a large header. # This is line 1980 of a file with a large header. # This is line 1981 of a file with a large header. # This is line 1982 of a file with a large header. # This is line 1983 of a file with a large header. # This is line 1984 of a file with a large header. # This is line 1985 of a file with a large header. # This is line 1986 of a file with a large header. # This is line 1987 of a file with a large header. # This is line 1988 of a file with a large header. # This is line 1989 of a file with a large header. # This is line 1990 of a file with a large header. # This is line 1991 of a file with a large header. # This is line 1992 of a file with a large header. # This is line 1993 of a file with a large header. # This is line 1994 of a file with a large header. # This is line 1995 of a file with a large header. # This is line 1996 of a file with a large header. # This is line 1997 of a file with a large header. # This is line 1998 of a file with a large header. # This is line 1999 of a file with a large header. # This is line 2000 of a file with a large header. # This is line 2001 of a file with a large header. # This is line 2002 of a file with a large header. # This is line 2003 of a file with a large header. # This is line 2004 of a file with a large header. # This is line 2005 of a file with a large header. # This is line 2006 of a file with a large header. # This is line 2007 of a file with a large header. # This is line 2008 of a file with a large header. # This is line 2009 of a file with a large header. # This is line 2010 of a file with a large header. # This is line 2011 of a file with a large header. # This is line 2012 of a file with a large header. # This is line 2013 of a file with a large header. # This is line 2014 of a file with a large header. # This is line 2015 of a file with a large header. # This is line 2016 of a file with a large header. # This is line 2017 of a file with a large header. # This is line 2018 of a file with a large header. # This is line 2019 of a file with a large header. # This is line 2020 of a file with a large header. # This is line 2021 of a file with a large header. # This is line 2022 of a file with a large header. # This is line 2023 of a file with a large header. # This is line 2024 of a file with a large header. # This is line 2025 of a file with a large header. # This is line 2026 of a file with a large header. # This is line 2027 of a file with a large header. # This is line 2028 of a file with a large header. # This is line 2029 of a file with a large header. # This is line 2030 of a file with a large header. # This is line 2031 of a file with a large header. # This is line 2032 of a file with a large header. # This is line 2033 of a file with a large header. # This is line 2034 of a file with a large header. # This is line 2035 of a file with a large header. # This is line 2036 of a file with a large header. # This is line 2037 of a file with a large header. # This is line 2038 of a file with a large header. # This is line 2039 of a file with a large header. # This is line 2040 of a file with a large header. # This is line 2041 of a file with a large header. # This is line 2042 of a file with a large header. # This is line 2043 of a file with a large header. # This is line 2044 of a file with a large header. # This is line 2045 of a file with a large header. # This is line 2046 of a file with a large header. # This is line 2047 of a file with a large header. # This is line 2048 of a file with a large header. # This is line 2049 of a file with a large header. # This is line 2050 of a file with a large header. # This is line 2051 of a file with a large header. # This is line 2052 of a file with a large header. # This is line 2053 of a file with a large header. # This is line 2054 of a file with a large header. # This is line 2055 of a file with a large header. # This is line 2056 of a file with a large header. # This is line 2057 of a file with a large header. # This is line 2058 of a file with a large header. # This is line 2059 of a file with a large header. # This is line 2060 of a file with a large header. # This is line 2061 of a file with a large header. # This is line 2062 of a file with a large header. # This is line 2063 of a file with a large header. # This is line 2064 of a file with a large header. # This is line 2065 of a file with a large header. # This is line 2066 of a file with a large header. # This is line 2067 of a file with a large header. # This is line 2068 of a file with a large header. # This is line 2069 of a file with a large header. # This is line 2070 of a file with a large header. # This is line 2071 of a file with a large header. # This is line 2072 of a file with a large header. # This is line 2073 of a file with a large header. # This is line 2074 of a file with a large header. # This is line 2075 of a file with a large header. # This is line 2076 of a file with a large header. # This is line 2077 of a file with a large header. # This is line 2078 of a file with a large header. # This is line 2079 of a file with a large header. # This is line 2080 of a file with a large header. # This is line 2081 of a file with a large header. # This is line 2082 of a file with a large header. # This is line 2083 of a file with a large header. # This is line 2084 of a file with a large header. # This is line 2085 of a file with a large header. # This is line 2086 of a file with a large header. # This is line 2087 of a file with a large header. # This is line 2088 of a file with a large header. # This is line 2089 of a file with a large header. # This is line 2090 of a file with a large header. # This is line 2091 of a file with a large header. # This is line 2092 of a file with a large header. # This is line 2093 of a file with a large header. # This is line 2094 of a file with a large header. # This is line 2095 of a file with a large header. # This is line 2096 of a file with a large header. # This is line 2097 of a file with a large header. # This is line 2098 of a file with a large header. # This is line 2099 of a file with a large header. # This is line 2100 of a file with a large header. # This is line 2101 of a file with a large header. # This is line 2102 of a file with a large header. # This is line 2103 of a file with a large header. # This is line 2104 of a file with a large header. # This is line 2105 of a file with a large header. # This is line 2106 of a file with a large header. # This is line 2107 of a file with a large header. # This is line 2108 of a file with a large header. # This is line 2109 of a file with a large header. # This is line 2110 of a file with a large header. # This is line 2111 of a file with a large header. # This is line 2112 of a file with a large header. # This is line 2113 of a file with a large header. # This is line 2114 of a file with a large header. # This is line 2115 of a file with a large header. # This is line 2116 of a file with a large header. # This is line 2117 of a file with a large header. # This is line 2118 of a file with a large header. # This is line 2119 of a file with a large header. # This is line 2120 of a file with a large header. # This is line 2121 of a file with a large header. # This is line 2122 of a file with a large header. # This is line 2123 of a file with a large header. # This is line 2124 of a file with a large header. # This is line 2125 of a file with a large header. # This is line 2126 of a file with a large header. # This is line 2127 of a file with a large header. # This is line 2128 of a file with a large header. # This is line 2129 of a file with a large header. # This is line 2130 of a file with a large header. # This is line 2131 of a file with a large header. # This is line 2132 of a file with a large header. # This is line 2133 of a file with a large header. # This is line 2134 of a file with a large header. # This is line 2135 of a file with a large header. # This is line 2136 of a file with a large header. # This is line 2137 of a file with a large header. # This is line 2138 of a file with a large header. # This is line 2139 of a file with a large header. # This is line 2140 of a file with a large header. # This is line 2141 of a file with a large header. # This is line 2142 of a file with a large header. # This is line 2143 of a file with a large header. # This is line 2144 of a file with a large header. # This is line 2145 of a file with a large header. # This is line 2146 of a file with a large header. # This is line 2147 of a file with a large header. # This is line 2148 of a file with a large header. # This is line 2149 of a file with a large header. # This is line 2150 of a file with a large header. # This is line 2151 of a file with a large header. # This is line 2152 of a file with a large header. # This is line 2153 of a file with a large header. # This is line 2154 of a file with a large header. # This is line 2155 of a file with a large header. # This is line 2156 of a file with a large header. # This is line 2157 of a file with a large header. # This is line 2158 of a file with a large header. # This is line 2159 of a file with a large header. # This is line 2160 of a file with a large header. # This is line 2161 of a file with a large header. # This is line 2162 of a file with a large header. # This is line 2163 of a file with a large header. # This is line 2164 of a file with a large header. # This is line 2165 of a file with a large header. # This is line 2166 of a file with a large header. # This is line 2167 of a file with a large header. # This is line 2168 of a file with a large header. # This is line 2169 of a file with a large header. # This is line 2170 of a file with a large header. # This is line 2171 of a file with a large header. # This is line 2172 of a file with a large header. # This is line 2173 of a file with a large header. # This is line 2174 of a file with a large header. # This is line 2175 of a file with a large header. # This is line 2176 of a file with a large header. # This is line 2177 of a file with a large header. # This is line 2178 of a file with a large header. # This is line 2179 of a file with a large header. # This is line 2180 of a file with a large header. # This is line 2181 of a file with a large header. # This is line 2182 of a file with a large header. # This is line 2183 of a file with a large header. # This is line 2184 of a file with a large header. # This is line 2185 of a file with a large header. # This is line 2186 of a file with a large header. # This is line 2187 of a file with a large header. # This is line 2188 of a file with a large header. # This is line 2189 of a file with a large header. # This is line 2190 of a file with a large header. # This is line 2191 of a file with a large header. # This is line 2192 of a file with a large header. # This is line 2193 of a file with a large header. # This is line 2194 of a file with a large header. # This is line 2195 of a file with a large header. # This is line 2196 of a file with a large header. # This is line 2197 of a file with a large header. # This is line 2198 of a file with a large header. # This is line 2199 of a file with a large header. # This is line 2200 of a file with a large header. # This is line 2201 of a file with a large header. # This is line 2202 of a file with a large header. # This is line 2203 of a file with a large header. # This is line 2204 of a file with a large header. # This is line 2205 of a file with a large header. # This is line 2206 of a file with a large header. # This is line 2207 of a file with a large header. # This is line 2208 of a file with a large header. # This is line 2209 of a file with a large header. # This is line 2210 of a file with a large header. # This is line 2211 of a file with a large header. # This is line 2212 of a file with a large header. # This is line 2213 of a file with a large header. # This is line 2214 of a file with a large header. # This is line 2215 of a file with a large header. # This is line 2216 of a file with a large header. # This is line 2217 of a file with a large header. # This is line 2218 of a file with a large header. # This is line 2219 of a file with a large header. # This is line 2220 of a file with a large header. # This is line 2221 of a file with a large header. # This is line 2222 of a file with a large header. # This is line 2223 of a file with a large header. # This is line 2224 of a file with a large header. # This is line 2225 of a file with a large header. # This is line 2226 of a file with a large header. # This is line 2227 of a file with a large header. # This is line 2228 of a file with a large header. # This is line 2229 of a file with a large header. # This is line 2230 of a file with a large header. # This is line 2231 of a file with a large header. # This is line 2232 of a file with a large header. # This is line 2233 of a file with a large header. # This is line 2234 of a file with a large header. # This is line 2235 of a file with a large header. # This is line 2236 of a file with a large header. # This is line 2237 of a file with a large header. # This is line 2238 of a file with a large header. # This is line 2239 of a file with a large header. # This is line 2240 of a file with a large header. # This is line 2241 of a file with a large header. # This is line 2242 of a file with a large header. # This is line 2243 of a file with a large header. # This is line 2244 of a file with a large header. # This is line 2245 of a file with a large header. # This is line 2246 of a file with a large header. # This is line 2247 of a file with a large header. # This is line 2248 of a file with a large header. # This is line 2249 of a file with a large header. # This is line 2250 of a file with a large header. # This is line 2251 of a file with a large header. # This is line 2252 of a file with a large header. # This is line 2253 of a file with a large header. # This is line 2254 of a file with a large header. # This is line 2255 of a file with a large header. # This is line 2256 of a file with a large header. # This is line 2257 of a file with a large header. # This is line 2258 of a file with a large header. # This is line 2259 of a file with a large header. # This is line 2260 of a file with a large header. # This is line 2261 of a file with a large header. # This is line 2262 of a file with a large header. # This is line 2263 of a file with a large header. # This is line 2264 of a file with a large header. # This is line 2265 of a file with a large header. # This is line 2266 of a file with a large header. # This is line 2267 of a file with a large header. # This is line 2268 of a file with a large header. # This is line 2269 of a file with a large header. # This is line 2270 of a file with a large header. # This is line 2271 of a file with a large header. # This is line 2272 of a file with a large header. # This is line 2273 of a file with a large header. # This is line 2274 of a file with a large header. # This is line 2275 of a file with a large header. # This is line 2276 of a file with a large header. # This is line 2277 of a file with a large header. # This is line 2278 of a file with a large header. # This is line 2279 of a file with a large header. # This is line 2280 of a file with a large header. # This is line 2281 of a file with a large header. # This is line 2282 of a file with a large header. # This is line 2283 of a file with a large header. # This is line 2284 of a file with a large header. # This is line 2285 of a file with a large header. # This is line 2286 of a file with a large header. # This is line 2287 of a file with a large header. # This is line 2288 of a file with a large header. # This is line 2289 of a file with a large header. # This is line 2290 of a file with a large header. # This is line 2291 of a file with a large header. # This is line 2292 of a file with a large header. # This is line 2293 of a file with a large header. # This is line 2294 of a file with a large header. # This is line 2295 of a file with a large header. # This is line 2296 of a file with a large header. # This is line 2297 of a file with a large header. # This is line 2298 of a file with a large header. # This is line 2299 of a file with a large header. # This is line 2300 of a file with a large header. # This is line 2301 of a file with a large header. # This is line 2302 of a file with a large header. # This is line 2303 of a file with a large header. # This is line 2304 of a file with a large header. # This is line 2305 of a file with a large header. # This is line 2306 of a file with a large header. # This is line 2307 of a file with a large header. # This is line 2308 of a file with a large header. # This is line 2309 of a file with a large header. # This is line 2310 of a file with a large header. # This is line 2311 of a file with a large header. # This is line 2312 of a file with a large header. # This is line 2313 of a file with a large header. # This is line 2314 of a file with a large header. # This is line 2315 of a file with a large header. # This is line 2316 of a file with a large header. # This is line 2317 of a file with a large header. # This is line 2318 of a file with a large header. # This is line 2319 of a file with a large header. # This is line 2320 of a file with a large header. # This is line 2321 of a file with a large header. # This is line 2322 of a file with a large header. # This is line 2323 of a file with a large header. # This is line 2324 of a file with a large header. # This is line 2325 of a file with a large header. # This is line 2326 of a file with a large header. # This is line 2327 of a file with a large header. # This is line 2328 of a file with a large header. # This is line 2329 of a file with a large header. # This is line 2330 of a file with a large header. # This is line 2331 of a file with a large header. # This is line 2332 of a file with a large header. # This is line 2333 of a file with a large header. # This is line 2334 of a file with a large header. # This is line 2335 of a file with a large header. # This is line 2336 of a file with a large header. # This is line 2337 of a file with a large header. # This is line 2338 of a file with a large header. # This is line 2339 of a file with a large header. # This is line 2340 of a file with a large header. # This is line 2341 of a file with a large header. # This is line 2342 of a file with a large header. # This is line 2343 of a file with a large header. # This is line 2344 of a file with a large header. # This is line 2345 of a file with a large header. # This is line 2346 of a file with a large header. # This is line 2347 of a file with a large header. # This is line 2348 of a file with a large header. # This is line 2349 of a file with a large header. # This is line 2350 of a file with a large header. # This is line 2351 of a file with a large header. # This is line 2352 of a file with a large header. # This is line 2353 of a file with a large header. # This is line 2354 of a file with a large header. # This is line 2355 of a file with a large header. # This is line 2356 of a file with a large header. # This is line 2357 of a file with a large header. # This is line 2358 of a file with a large header. # This is line 2359 of a file with a large header. # This is line 2360 of a file with a large header. # This is line 2361 of a file with a large header. # This is line 2362 of a file with a large header. # This is line 2363 of a file with a large header. # This is line 2364 of a file with a large header. # This is line 2365 of a file with a large header. # This is line 2366 of a file with a large header. # This is line 2367 of a file with a large header. # This is line 2368 of a file with a large header. # This is line 2369 of a file with a large header. # This is line 2370 of a file with a large header. # This is line 2371 of a file with a large header. # This is line 2372 of a file with a large header. # This is line 2373 of a file with a large header. # This is line 2374 of a file with a large header. # This is line 2375 of a file with a large header. # This is line 2376 of a file with a large header. # This is line 2377 of a file with a large header. # This is line 2378 of a file with a large header. # This is line 2379 of a file with a large header. # This is line 2380 of a file with a large header. # This is line 2381 of a file with a large header. # This is line 2382 of a file with a large header. # This is line 2383 of a file with a large header. # This is line 2384 of a file with a large header. # This is line 2385 of a file with a large header. # This is line 2386 of a file with a large header. # This is line 2387 of a file with a large header. # This is line 2388 of a file with a large header. # This is line 2389 of a file with a large header. # This is line 2390 of a file with a large header. # This is line 2391 of a file with a large header. # This is line 2392 of a file with a large header. # This is line 2393 of a file with a large header. # This is line 2394 of a file with a large header. # This is line 2395 of a file with a large header. # This is line 2396 of a file with a large header. # This is line 2397 of a file with a large header. # This is line 2398 of a file with a large header. # This is line 2399 of a file with a large header. # This is line 2400 of a file with a large header. # This is line 2401 of a file with a large header. # This is line 2402 of a file with a large header. # This is line 2403 of a file with a large header. # This is line 2404 of a file with a large header. # This is line 2405 of a file with a large header. # This is line 2406 of a file with a large header. # This is line 2407 of a file with a large header. # This is line 2408 of a file with a large header. # This is line 2409 of a file with a large header. # This is line 2410 of a file with a large header. # This is line 2411 of a file with a large header. # This is line 2412 of a file with a large header. # This is line 2413 of a file with a large header. # This is line 2414 of a file with a large header. # This is line 2415 of a file with a large header. # This is line 2416 of a file with a large header. # This is line 2417 of a file with a large header. # This is line 2418 of a file with a large header. # This is line 2419 of a file with a large header. # This is line 2420 of a file with a large header. # This is line 2421 of a file with a large header. # This is line 2422 of a file with a large header. # This is line 2423 of a file with a large header. # This is line 2424 of a file with a large header. # This is line 2425 of a file with a large header. # This is line 2426 of a file with a large header. # This is line 2427 of a file with a large header. # This is line 2428 of a file with a large header. # This is line 2429 of a file with a large header. # This is line 2430 of a file with a large header. # This is line 2431 of a file with a large header. # This is line 2432 of a file with a large header. # This is line 2433 of a file with a large header. # This is line 2434 of a file with a large header. # This is line 2435 of a file with a large header. # This is line 2436 of a file with a large header. # This is line 2437 of a file with a large header. # This is line 2438 of a file with a large header. # This is line 2439 of a file with a large header. # This is line 2440 of a file with a large header. # This is line 2441 of a file with a large header. # This is line 2442 of a file with a large header. # This is line 2443 of a file with a large header. # This is line 2444 of a file with a large header. # This is line 2445 of a file with a large header. # This is line 2446 of a file with a large header. # This is line 2447 of a file with a large header. # This is line 2448 of a file with a large header. # This is line 2449 of a file with a large header. # This is line 2450 of a file with a large header. # This is line 2451 of a file with a large header. # This is line 2452 of a file with a large header. # This is line 2453 of a file with a large header. # This is line 2454 of a file with a large header. # This is line 2455 of a file with a large header. # This is line 2456 of a file with a large header. # This is line 2457 of a file with a large header. # This is line 2458 of a file with a large header. # This is line 2459 of a file with a large header. # This is line 2460 of a file with a large header. # This is line 2461 of a file with a large header. # This is line 2462 of a file with a large header. # This is line 2463 of a file with a large header. # This is line 2464 of a file with a large header. # This is line 2465 of a file with a large header. # This is line 2466 of a file with a large header. # This is line 2467 of a file with a large header. # This is line 2468 of a file with a large header. # This is line 2469 of a file with a large header. # This is line 2470 of a file with a large header. # This is line 2471 of a file with a large header. # This is line 2472 of a file with a large header. # This is line 2473 of a file with a large header. # This is line 2474 of a file with a large header. # This is line 2475 of a file with a large header. # This is line 2476 of a file with a large header. # This is line 2477 of a file with a large header. # This is line 2478 of a file with a large header. # This is line 2479 of a file with a large header. # This is line 2480 of a file with a large header. # This is line 2481 of a file with a large header. # This is line 2482 of a file with a large header. # This is line 2483 of a file with a large header. # This is line 2484 of a file with a large header. # This is line 2485 of a file with a large header. # This is line 2486 of a file with a large header. # This is line 2487 of a file with a large header. # This is line 2488 of a file with a large header. # This is line 2489 of a file with a large header. # This is line 2490 of a file with a large header. # This is line 2491 of a file with a large header. # This is line 2492 of a file with a large header. # This is line 2493 of a file with a large header. # This is line 2494 of a file with a large header. # This is line 2495 of a file with a large header. # This is line 2496 of a file with a large header. # This is line 2497 of a file with a large header. # This is line 2498 of a file with a large header. # This is line 2499 of a file with a large header. # This is line 2500 of a file with a large header. # This is line 2501 of a file with a large header. # This is line 2502 of a file with a large header. # This is line 2503 of a file with a large header. # This is line 2504 of a file with a large header. # This is line 2505 of a file with a large header. # This is line 2506 of a file with a large header. # This is line 2507 of a file with a large header. # This is line 2508 of a file with a large header. # This is line 2509 of a file with a large header. # This is line 2510 of a file with a large header. # This is line 2511 of a file with a large header. # This is line 2512 of a file with a large header. # This is line 2513 of a file with a large header. # This is line 2514 of a file with a large header. # This is line 2515 of a file with a large header. # This is line 2516 of a file with a large header. # This is line 2517 of a file with a large header. # This is line 2518 of a file with a large header. # This is line 2519 of a file with a large header. # This is line 2520 of a file with a large header. # This is line 2521 of a file with a large header. # This is line 2522 of a file with a large header. # This is line 2523 of a file with a large header. # This is line 2524 of a file with a large header. # This is line 2525 of a file with a large header. # This is line 2526 of a file with a large header. # This is line 2527 of a file with a large header. # This is line 2528 of a file with a large header. # This is line 2529 of a file with a large header. # This is line 2530 of a file with a large header. # This is line 2531 of a file with a large header. # This is line 2532 of a file with a large header. # This is line 2533 of a file with a large header. # This is line 2534 of a file with a large header. # This is line 2535 of a file with a large header. # This is line 2536 of a file with a large header. # This is line 2537 of a file with a large header. # This is line 2538 of a file with a large header. # This is line 2539 of a file with a large header. # This is line 2540 of a file with a large header. # This is line 2541 of a file with a large header. # This is line 2542 of a file with a large header. # This is line 2543 of a file with a large header. # This is line 2544 of a file with a large header. # This is line 2545 of a file with a large header. # This is line 2546 of a file with a large header. # This is line 2547 of a file with a large header. # This is line 2548 of a file with a large header. # This is line 2549 of a file with a large header. # This is line 2550 of a file with a large header. # This is line 2551 of a file with a large header. # This is line 2552 of a file with a large header. # This is line 2553 of a file with a large header. # This is line 2554 of a file with a large header. # This is line 2555 of a file with a large header. # This is line 2556 of a file with a large header. # This is line 2557 of a file with a large header. # This is line 2558 of a file with a large header. # This is line 2559 of a file with a large header. # This is line 2560 of a file with a large header. # This is line 2561 of a file with a large header. # This is line 2562 of a file with a large header. # This is line 2563 of a file with a large header. # This is line 2564 of a file with a large header. # This is line 2565 of a file with a large header. # This is line 2566 of a file with a large header. # This is line 2567 of a file with a large header. # This is line 2568 of a file with a large header. # This is line 2569 of a file with a large header. # This is line 2570 of a file with a large header. # This is line 2571 of a file with a large header. # This is line 2572 of a file with a large header. # This is line 2573 of a file with a large header. # This is line 2574 of a file with a large header. # This is line 2575 of a file with a large header. # This is line 2576 of a file with a large header. # This is line 2577 of a file with a large header. # This is line 2578 of a file with a large header. # This is line 2579 of a file with a large header. # This is line 2580 of a file with a large header. # This is line 2581 of a file with a large header. # This is line 2582 of a file with a large header. # This is line 2583 of a file with a large header. # This is line 2584 of a file with a large header. # This is line 2585 of a file with a large header. # This is line 2586 of a file with a large header. # This is line 2587 of a file with a large header. # This is line 2588 of a file with a large header. # This is line 2589 of a file with a large header. # This is line 2590 of a file with a large header. # This is line 2591 of a file with a large header. # This is line 2592 of a file with a large header. # This is line 2593 of a file with a large header. # This is line 2594 of a file with a large header. # This is line 2595 of a file with a large header. # This is line 2596 of a file with a large header. # This is line 2597 of a file with a large header. # This is line 2598 of a file with a large header. # This is line 2599 of a file with a large header. # This is line 2600 of a file with a large header. # This is line 2601 of a file with a large header. # This is line 2602 of a file with a large header. # This is line 2603 of a file with a large header. # This is line 2604 of a file with a large header. # This is line 2605 of a file with a large header. # This is line 2606 of a file with a large header. # This is line 2607 of a file with a large header. # This is line 2608 of a file with a large header. # This is line 2609 of a file with a large header. # This is line 2610 of a file with a large header. # This is line 2611 of a file with a large header. # This is line 2612 of a file with a large header. # This is line 2613 of a file with a large header. # This is line 2614 of a file with a large header. # This is line 2615 of a file with a large header. # This is line 2616 of a file with a large header. # This is line 2617 of a file with a large header. # This is line 2618 of a file with a large header. # This is line 2619 of a file with a large header. # This is line 2620 of a file with a large header. # This is line 2621 of a file with a large header. # This is line 2622 of a file with a large header. # This is line 2623 of a file with a large header. # This is line 2624 of a file with a large header. # This is line 2625 of a file with a large header. # This is line 2626 of a file with a large header. # This is line 2627 of a file with a large header. # This is line 2628 of a file with a large header. # This is line 2629 of a file with a large header. # This is line 2630 of a file with a large header. # This is line 2631 of a file with a large header. # This is line 2632 of a file with a large header. # This is line 2633 of a file with a large header. # This is line 2634 of a file with a large header. # This is line 2635 of a file with a large header. # This is line 2636 of a file with a large header. # This is line 2637 of a file with a large header. # This is line 2638 of a file with a large header. # This is line 2639 of a file with a large header. # This is line 2640 of a file with a large header. # This is line 2641 of a file with a large header. # This is line 2642 of a file with a large header. # This is line 2643 of a file with a large header. # This is line 2644 of a file with a large header. # This is line 2645 of a file with a large header. # This is line 2646 of a file with a large header. # This is line 2647 of a file with a large header. # This is line 2648 of a file with a large header. # This is line 2649 of a file with a large header. # This is line 2650 of a file with a large header. # This is line 2651 of a file with a large header. # This is line 2652 of a file with a large header. # This is line 2653 of a file with a large header. # This is line 2654 of a file with a large header. # This is line 2655 of a file with a large header. # This is line 2656 of a file with a large header. # This is line 2657 of a file with a large header. # This is line 2658 of a file with a large header. # This is line 2659 of a file with a large header. # This is line 2660 of a file with a large header. # This is line 2661 of a file with a large header. # This is line 2662 of a file with a large header. # This is line 2663 of a file with a large header. # This is line 2664 of a file with a large header. # This is line 2665 of a file with a large header. # This is line 2666 of a file with a large header. # This is line 2667 of a file with a large header. # This is line 2668 of a file with a large header. # This is line 2669 of a file with a large header. # This is line 2670 of a file with a large header. # This is line 2671 of a file with a large header. # This is line 2672 of a file with a large header. # This is line 2673 of a file with a large header. # This is line 2674 of a file with a large header. # This is line 2675 of a file with a large header. # This is line 2676 of a file with a large header. # This is line 2677 of a file with a large header. # This is line 2678 of a file with a large header. # This is line 2679 of a file with a large header. # This is line 2680 of a file with a large header. # This is line 2681 of a file with a large header. # This is line 2682 of a file with a large header. # This is line 2683 of a file with a large header. # This is line 2684 of a file with a large header. # This is line 2685 of a file with a large header. # This is line 2686 of a file with a large header. # This is line 2687 of a file with a large header. # This is line 2688 of a file with a large header. # This is line 2689 of a file with a large header. # This is line 2690 of a file with a large header. # This is line 2691 of a file with a large header. # This is line 2692 of a file with a large header. # This is line 2693 of a file with a large header. # This is line 2694 of a file with a large header. # This is line 2695 of a file with a large header. # This is line 2696 of a file with a large header. # This is line 2697 of a file with a large header. # This is line 2698 of a file with a large header. # This is line 2699 of a file with a large header. # This is line 2700 of a file with a large header. # This is line 2701 of a file with a large header. # This is line 2702 of a file with a large header. # This is line 2703 of a file with a large header. # This is line 2704 of a file with a large header. # This is line 2705 of a file with a large header. # This is line 2706 of a file with a large header. # This is line 2707 of a file with a large header. # This is line 2708 of a file with a large header. # This is line 2709 of a file with a large header. # This is line 2710 of a file with a large header. # This is line 2711 of a file with a large header. # This is line 2712 of a file with a large header. # This is line 2713 of a file with a large header. # This is line 2714 of a file with a large header. # This is line 2715 of a file with a large header. # This is line 2716 of a file with a large header. # This is line 2717 of a file with a large header. # This is line 2718 of a file with a large header. # This is line 2719 of a file with a large header. # This is line 2720 of a file with a large header. # This is line 2721 of a file with a large header. # This is line 2722 of a file with a large header. # This is line 2723 of a file with a large header. # This is line 2724 of a file with a large header. # This is line 2725 of a file with a large header. # This is line 2726 of a file with a large header. # This is line 2727 of a file with a large header. # This is line 2728 of a file with a large header. # This is line 2729 of a file with a large header. # This is line 2730 of a file with a large header. # This is line 2731 of a file with a large header. # This is line 2732 of a file with a large header. # This is line 2733 of a file with a large header. # This is line 2734 of a file with a large header. # This is line 2735 of a file with a large header. # This is line 2736 of a file with a large header. # This is line 2737 of a file with a large header. # This is line 2738 of a file with a large header. # This is line 2739 of a file with a large header. # This is line 2740 of a file with a large header. # This is line 2741 of a file with a large header. # This is line 2742 of a file with a large header. # This is line 2743 of a file with a large header. # This is line 2744 of a file with a large header. # This is line 2745 of a file with a large header. # This is line 2746 of a file with a large header. # This is line 2747 of a file with a large header. # This is line 2748 of a file with a large header. # This is line 2749 of a file with a large header. # This is line 2750 of a file with a large header. # This is line 2751 of a file with a large header. # This is line 2752 of a file with a large header. # This is line 2753 of a file with a large header. # This is line 2754 of a file with a large header. # This is line 2755 of a file with a large header. # This is line 2756 of a file with a large header. # This is line 2757 of a file with a large header. # This is line 2758 of a file with a large header. # This is line 2759 of a file with a large header. # This is line 2760 of a file with a large header. # This is line 2761 of a file with a large header. # This is line 2762 of a file with a large header. # This is line 2763 of a file with a large header. # This is line 2764 of a file with a large header. # This is line 2765 of a file with a large header. # This is line 2766 of a file with a large header. # This is line 2767 of a file with a large header. # This is line 2768 of a file with a large header. # This is line 2769 of a file with a large header. # This is line 2770 of a file with a large header. # This is line 2771 of a file with a large header. # This is line 2772 of a file with a large header. # This is line 2773 of a file with a large header. # This is line 2774 of a file with a large header. # This is line 2775 of a file with a large header. # This is line 2776 of a file with a large header. # This is line 2777 of a file with a large header. # This is line 2778 of a file with a large header. # This is line 2779 of a file with a large header. # This is line 2780 of a file with a large header. # This is line 2781 of a file with a large header. # This is line 2782 of a file with a large header. # This is line 2783 of a file with a large header. # This is line 2784 of a file with a large header. # This is line 2785 of a file with a large header. # This is line 2786 of a file with a large header. # This is line 2787 of a file with a large header. # This is line 2788 of a file with a large header. # This is line 2789 of a file with a large header. # This is line 2790 of a file with a large header. # This is line 2791 of a file with a large header. # This is line 2792 of a file with a large header. # This is line 2793 of a file with a large header. # This is line 2794 of a file with a large header. # This is line 2795 of a file with a large header. # This is line 2796 of a file with a large header. # This is line 2797 of a file with a large header. # This is line 2798 of a file with a large header. # This is line 2799 of a file with a large header. # This is line 2800 of a file with a large header. # This is line 2801 of a file with a large header. # This is line 2802 of a file with a large header. # This is line 2803 of a file with a large header. # This is line 2804 of a file with a large header. # This is line 2805 of a file with a large header. # This is line 2806 of a file with a large header. # This is line 2807 of a file with a large header. # This is line 2808 of a file with a large header. # This is line 2809 of a file with a large header. # This is line 2810 of a file with a large header. # This is line 2811 of a file with a large header. # This is line 2812 of a file with a large header. # This is line 2813 of a file with a large header. # This is line 2814 of a file with a large header. # This is line 2815 of a file with a large header. # This is line 2816 of a file with a large header. # This is line 2817 of a file with a large header. # This is line 2818 of a file with a large header. # This is line 2819 of a file with a large header. # This is line 2820 of a file with a large header. # This is line 2821 of a file with a large header. # This is line 2822 of a file with a large header. # This is line 2823 of a file with a large header. # This is line 2824 of a file with a large header. # This is line 2825 of a file with a large header. # This is line 2826 of a file with a large header. # This is line 2827 of a file with a large header. # This is line 2828 of a file with a large header. # This is line 2829 of a file with a large header. # This is line 2830 of a file with a large header. # This is line 2831 of a file with a large header. # This is line 2832 of a file with a large header. # This is line 2833 of a file with a large header. # This is line 2834 of a file with a large header. # This is line 2835 of a file with a large header. # This is line 2836 of a file with a large header. # This is line 2837 of a file with a large header. # This is line 2838 of a file with a large header. # This is line 2839 of a file with a large header. # This is line 2840 of a file with a large header. # This is line 2841 of a file with a large header. # This is line 2842 of a file with a large header. # This is line 2843 of a file with a large header. # This is line 2844 of a file with a large header. # This is line 2845 of a file with a large header. # This is line 2846 of a file with a large header. # This is line 2847 of a file with a large header. # This is line 2848 of a file with a large header. # This is line 2849 of a file with a large header. # This is line 2850 of a file with a large header. # This is line 2851 of a file with a large header. # This is line 2852 of a file with a large header. # This is line 2853 of a file with a large header. # This is line 2854 of a file with a large header. # This is line 2855 of a file with a large header. # This is line 2856 of a file with a large header. # This is line 2857 of a file with a large header. # This is line 2858 of a file with a large header. # This is line 2859 of a file with a large header. # This is line 2860 of a file with a large header. # This is line 2861 of a file with a large header. # This is line 2862 of a file with a large header. # This is line 2863 of a file with a large header. # This is line 2864 of a file with a large header. # This is line 2865 of a file with a large header. # This is line 2866 of a file with a large header. # This is line 2867 of a file with a large header. # This is line 2868 of a file with a large header. # This is line 2869 of a file with a large header. # This is line 2870 of a file with a large header. # This is line 2871 of a file with a large header. # This is line 2872 of a file with a large header. # This is line 2873 of a file with a large header. # This is line 2874 of a file with a large header. # This is line 2875 of a file with a large header. # This is line 2876 of a file with a large header. # This is line 2877 of a file with a large header. # This is line 2878 of a file with a large header. # This is line 2879 of a file with a large header. # This is line 2880 of a file with a large header. # This is line 2881 of a file with a large header. # This is line 2882 of a file with a large header. # This is line 2883 of a file with a large header. # This is line 2884 of a file with a large header. # This is line 2885 of a file with a large header. # This is line 2886 of a file with a large header. # This is line 2887 of a file with a large header. # This is line 2888 of a file with a large header. # This is line 2889 of a file with a large header. # This is line 2890 of a file with a large header. # This is line 2891 of a file with a large header. # This is line 2892 of a file with a large header. # This is line 2893 of a file with a large header. # This is line 2894 of a file with a large header. # This is line 2895 of a file with a large header. # This is line 2896 of a file with a large header. # This is line 2897 of a file with a large header. # This is line 2898 of a file with a large header. # This is line 2899 of a file with a large header. # This is line 2900 of a file with a large header. # This is line 2901 of a file with a large header. # This is line 2902 of a file with a large header. # This is line 2903 of a file with a large header. # This is line 2904 of a file with a large header. # This is line 2905 of a file with a large header. # This is line 2906 of a file with a large header. # This is line 2907 of a file with a large header. # This is line 2908 of a file with a large header. # This is line 2909 of a file with a large header. # This is line 2910 of a file with a large header. # This is line 2911 of a file with a large header. # This is line 2912 of a file with a large header. # This is line 2913 of a file with a large header. # This is line 2914 of a file with a large header. # This is line 2915 of a file with a large header. # This is line 2916 of a file with a large header. # This is line 2917 of a file with a large header. # This is line 2918 of a file with a large header. # This is line 2919 of a file with a large header. # This is line 2920 of a file with a large header. # This is line 2921 of a file with a large header. # This is line 2922 of a file with a large header. # This is line 2923 of a file with a large header. # This is line 2924 of a file with a large header. # This is line 2925 of a file with a large header. # This is line 2926 of a file with a large header. # This is line 2927 of a file with a large header. # This is line 2928 of a file with a large header. # This is line 2929 of a file with a large header. # This is line 2930 of a file with a large header. # This is line 2931 of a file with a large header. # This is line 2932 of a file with a large header. # This is line 2933 of a file with a large header. # This is line 2934 of a file with a large header. # This is line 2935 of a file with a large header. # This is line 2936 of a file with a large header. # This is line 2937 of a file with a large header. # This is line 2938 of a file with a large header. # This is line 2939 of a file with a large header. # This is line 2940 of a file with a large header. # This is line 2941 of a file with a large header. # This is line 2942 of a file with a large header. # This is line 2943 of a file with a large header. # This is line 2944 of a file with a large header. # This is line 2945 of a file with a large header. # This is line 2946 of a file with a large header. # This is line 2947 of a file with a large header. # This is line 2948 of a file with a large header. # This is line 2949 of a file with a large header. # This is line 2950 of a file with a large header. # This is line 2951 of a file with a large header. # This is line 2952 of a file with a large header. # This is line 2953 of a file with a large header. # This is line 2954 of a file with a large header. # This is line 2955 of a file with a large header. # This is line 2956 of a file with a large header. # This is line 2957 of a file with a large header. # This is line 2958 of a file with a large header. # This is line 2959 of a file with a large header. # This is line 2960 of a file with a large header. # This is line 2961 of a file with a large header. # This is line 2962 of a file with a large header. # This is line 2963 of a file with a large header. # This is line 2964 of a file with a large header. # This is line 2965 of a file with a large header. # This is line 2966 of a file with a large header. # This is line 2967 of a file with a large header. # This is line 2968 of a file with a large header. # This is line 2969 of a file with a large header. # This is line 2970 of a file with a large header. # This is line 2971 of a file with a large header. # This is line 2972 of a file with a large header. # This is line 2973 of a file with a large header. # This is line 2974 of a file with a large header. # This is line 2975 of a file with a large header. # This is line 2976 of a file with a large header. # This is line 2977 of a file with a large header. # This is line 2978 of a file with a large header. # This is line 2979 of a file with a large header. # This is line 2980 of a file with a large header. # This is line 2981 of a file with a large header. # This is line 2982 of a file with a large header. # This is line 2983 of a file with a large header. # This is line 2984 of a file with a large header. # This is line 2985 of a file with a large header. # This is line 2986 of a file with a large header. # This is line 2987 of a file with a large header. # This is line 2988 of a file with a large header. # This is line 2989 of a file with a large header. # This is line 2990 of a file with a large header. # This is line 2991 of a file with a large header. # This is line 2992 of a file with a large header. # This is line 2993 of a file with a large header. # This is line 2994 of a file with a large header. # This is line 2995 of a file with a large header. # This is line 2996 of a file with a large header. # This is line 2997 of a file with a large header. # This is line 2998 of a file with a large header. # This is line 2999 of a file with a large header. # This is line 3000 of a file with a large header. # This is line 3001 of a file with a large header. # This is line 3002 of a file with a large header. # This is line 3003 of a file with a large header. # This is line 3004 of a file with a large header. # This is line 3005 of a file with a large header. # This is line 3006 of a file with a large header. # This is line 3007 of a file with a large header. # This is line 3008 of a file with a large header. # This is line 3009 of a file with a large header. # This is line 3010 of a file with a large header. # This is line 3011 of a file with a large header. # This is line 3012 of a file with a large header. # This is line 3013 of a file with a large header. # This is line 3014 of a file with a large header. # This is line 3015 of a file with a large header. # This is line 3016 of a file with a large header. # This is line 3017 of a file with a large header. # This is line 3018 of a file with a large header. # This is line 3019 of a file with a large header. # This is line 3020 of a file with a large header. # This is line 3021 of a file with a large header. # This is line 3022 of a file with a large header. # This is line 3023 of a file with a large header. # This is line 3024 of a file with a large header. # This is line 3025 of a file with a large header. # This is line 3026 of a file with a large header. # This is line 3027 of a file with a large header. # This is line 3028 of a file with a large header. # This is line 3029 of a file with a large header. # This is line 3030 of a file with a large header. # This is line 3031 of a file with a large header. # This is line 3032 of a file with a large header. # This is line 3033 of a file with a large header. # This is line 3034 of a file with a large header. # This is line 3035 of a file with a large header. # This is line 3036 of a file with a large header. # This is line 3037 of a file with a large header. # This is line 3038 of a file with a large header. # This is line 3039 of a file with a large header. # This is line 3040 of a file with a large header. # This is line 3041 of a file with a large header. # This is line 3042 of a file with a large header. # This is line 3043 of a file with a large header. # This is line 3044 of a file with a large header. # This is line 3045 of a file with a large header. # This is line 3046 of a file with a large header. # This is line 3047 of a file with a large header. # This is line 3048 of a file with a large header. # This is line 3049 of a file with a large header. # This is line 3050 of a file with a large header. # This is line 3051 of a file with a large header. # This is line 3052 of a file with a large header. # This is line 3053 of a file with a large header. # This is line 3054 of a file with a large header. # This is line 3055 of a file with a large header. # This is line 3056 of a file with a large header. # This is line 3057 of a file with a large header. # This is line 3058 of a file with a large header. # This is line 3059 of a file with a large header. # This is line 3060 of a file with a large header. # This is line 3061 of a file with a large header. # This is line 3062 of a file with a large header. # This is line 3063 of a file with a large header. # This is line 3064 of a file with a large header. # This is line 3065 of a file with a large header. # This is line 3066 of a file with a large header. # This is line 3067 of a file with a large header. # This is line 3068 of a file with a large header. # This is line 3069 of a file with a large header. # This is line 3070 of a file with a large header. # This is line 3071 of a file with a large header. # This is line 3072 of a file with a large header. # This is line 3073 of a file with a large header. # This is line 3074 of a file with a large header. # This is line 3075 of a file with a large header. # This is line 3076 of a file with a large header. # This is line 3077 of a file with a large header. # This is line 3078 of a file with a large header. # This is line 3079 of a file with a large header. # This is line 3080 of a file with a large header. # This is line 3081 of a file with a large header. # This is line 3082 of a file with a large header. # This is line 3083 of a file with a large header. # This is line 3084 of a file with a large header. # This is line 3085 of a file with a large header. # This is line 3086 of a file with a large header. # This is line 3087 of a file with a large header. # This is line 3088 of a file with a large header. # This is line 3089 of a file with a large header. # This is line 3090 of a file with a large header. # This is line 3091 of a file with a large header. # This is line 3092 of a file with a large header. # This is line 3093 of a file with a large header. # This is line 3094 of a file with a large header. # This is line 3095 of a file with a large header. # This is line 3096 of a file with a large header. # This is line 3097 of a file with a large header. # This is line 3098 of a file with a large header. # This is line 3099 of a file with a large header. # This is line 3100 of a file with a large header. # This is line 3101 of a file with a large header. # This is line 3102 of a file with a large header. # This is line 3103 of a file with a large header. # This is line 3104 of a file with a large header. # This is line 3105 of a file with a large header. # This is line 3106 of a file with a large header. # This is line 3107 of a file with a large header. # This is line 3108 of a file with a large header. # This is line 3109 of a file with a large header. # This is line 3110 of a file with a large header. # This is line 3111 of a file with a large header. # This is line 3112 of a file with a large header. # This is line 3113 of a file with a large header. # This is line 3114 of a file with a large header. # This is line 3115 of a file with a large header. # This is line 3116 of a file with a large header. # This is line 3117 of a file with a large header. # This is line 3118 of a file with a large header. # This is line 3119 of a file with a large header. # This is line 3120 of a file with a large header. # This is line 3121 of a file with a large header. # This is line 3122 of a file with a large header. # This is line 3123 of a file with a large header. # This is line 3124 of a file with a large header. # This is line 3125 of a file with a large header. # This is line 3126 of a file with a large header. # This is line 3127 of a file with a large header. # This is line 3128 of a file with a large header. # This is line 3129 of a file with a large header. # This is line 3130 of a file with a large header. # This is line 3131 of a file with a large header. # This is line 3132 of a file with a large header. # This is line 3133 of a file with a large header. # This is line 3134 of a file with a large header. # This is line 3135 of a file with a large header. # This is line 3136 of a file with a large header. # This is line 3137 of a file with a large header. # This is line 3138 of a file with a large header. # This is line 3139 of a file with a large header. # This is line 3140 of a file with a large header. # This is line 3141 of a file with a large header. # This is line 3142 of a file with a large header. # This is line 3143 of a file with a large header. # This is line 3144 of a file with a large header. # This is line 3145 of a file with a large header. # This is line 3146 of a file with a large header. # This is line 3147 of a file with a large header. # This is line 3148 of a file with a large header. # This is line 3149 of a file with a large header. # This is line 3150 of a file with a large header. # This is line 3151 of a file with a large header. # This is line 3152 of a file with a large header. # This is line 3153 of a file with a large header. # This is line 3154 of a file with a large header. # This is line 3155 of a file with a large header. # This is line 3156 of a file with a large header. # This is line 3157 of a file with a large header. # This is line 3158 of a file with a large header. # This is line 3159 of a file with a large header. # This is line 3160 of a file with a large header. # This is line 3161 of a file with a large header. # This is line 3162 of a file with a large header. # This is line 3163 of a file with a large header. # This is line 3164 of a file with a large header. # This is line 3165 of a file with a large header. # This is line 3166 of a file with a large header. # This is line 3167 of a file with a large header. # This is line 3168 of a file with a large header. # This is line 3169 of a file with a large header. # This is line 3170 of a file with a large header. # This is line 3171 of a file with a large header. # This is line 3172 of a file with a large header. # This is line 3173 of a file with a large header. # This is line 3174 of a file with a large header. # This is line 3175 of a file with a large header. # This is line 3176 of a file with a large header. # This is line 3177 of a file with a large header. # This is line 3178 of a file with a large header. # This is line 3179 of a file with a large header. # This is line 3180 of a file with a large header. # This is line 3181 of a file with a large header. # This is line 3182 of a file with a large header. # This is line 3183 of a file with a large header. # This is line 3184 of a file with a large header. # This is line 3185 of a file with a large header. # This is line 3186 of a file with a large header. # This is line 3187 of a file with a large header. # This is line 3188 of a file with a large header. # This is line 3189 of a file with a large header. # This is line 3190 of a file with a large header. # This is line 3191 of a file with a large header. # This is line 3192 of a file with a large header. # This is line 3193 of a file with a large header. # This is line 3194 of a file with a large header. # This is line 3195 of a file with a large header. # This is line 3196 of a file with a large header. # This is line 3197 of a file with a large header. # This is line 3198 of a file with a large header. # This is line 3199 of a file with a large header. # This is line 3200 of a file with a large header. # This is line 3201 of a file with a large header. # This is line 3202 of a file with a large header. # This is line 3203 of a file with a large header. # This is line 3204 of a file with a large header. # This is line 3205 of a file with a large header. # This is line 3206 of a file with a large header. # This is line 3207 of a file with a large header. # This is line 3208 of a file with a large header. # This is line 3209 of a file with a large header. # This is line 3210 of a file with a large header. # This is line 3211 of a file with a large header. # This is line 3212 of a file with a large header. # This is line 3213 of a file with a large header. # This is line 3214 of a file with a large header. # This is line 3215 of a file with a large header. # This is line 3216 of a file with a large header. # This is line 3217 of a file with a large header. # This is line 3218 of a file with a large header. # This is line 3219 of a file with a large header. # This is line 3220 of a file with a large header. # This is line 3221 of a file with a large header. # This is line 3222 of a file with a large header. # This is line 3223 of a file with a large header. # This is line 3224 of a file with a large header. # This is line 3225 of a file with a large header. # This is line 3226 of a file with a large header. # This is line 3227 of a file with a large header. # This is line 3228 of a file with a large header. # This is line 3229 of a file with a large header. # This is line 3230 of a file with a large header. # This is line 3231 of a file with a large header. # This is line 3232 of a file with a large header. # This is line 3233 of a file with a large header. # This is line 3234 of a file with a large header. # This is line 3235 of a file with a large header. # This is line 3236 of a file with a large header. # This is line 3237 of a file with a large header. # This is line 3238 of a file with a large header. # This is line 3239 of a file with a large header. # This is line 3240 of a file with a large header. # This is line 3241 of a file with a large header. # This is line 3242 of a file with a large header. # This is line 3243 of a file with a large header. # This is line 3244 of a file with a large header. # This is line 3245 of a file with a large header. # This is line 3246 of a file with a large header. # This is line 3247 of a file with a large header. # This is line 3248 of a file with a large header. # This is line 3249 of a file with a large header. # This is line 3250 of a file with a large header. # This is line 3251 of a file with a large header. # This is line 3252 of a file with a large header. # This is line 3253 of a file with a large header. # This is line 3254 of a file with a large header. # This is line 3255 of a file with a large header. # This is line 3256 of a file with a large header. # This is line 3257 of a file with a large header. # This is line 3258 of a file with a large header. # This is line 3259 of a file with a large header. # This is line 3260 of a file with a large header. # This is line 3261 of a file with a large header. # This is line 3262 of a file with a large header. # This is line 3263 of a file with a large header. # This is line 3264 of a file with a large header. # This is line 3265 of a file with a large header. # This is line 3266 of a file with a large header. # This is line 3267 of a file with a large header. # This is line 3268 of a file with a large header. # This is line 3269 of a file with a large header. # This is line 3270 of a file with a large header. # This is line 3271 of a file with a large header. # This is line 3272 of a file with a large header. # This is line 3273 of a file with a large header. # This is line 3274 of a file with a large header. # This is line 3275 of a file with a large header. # This is line 3276 of a file with a large header. # This is line 3277 of a file with a large header. # This is line 3278 of a file with a large header. # This is line 3279 of a file with a large header. # This is line 3280 of a file with a large header. # This is line 3281 of a file with a large header. # This is line 3282 of a file with a large header. # This is line 3283 of a file with a large header. # This is line 3284 of a file with a large header. # This is line 3285 of a file with a large header. # This is line 3286 of a file with a large header. # This is line 3287 of a file with a large header. # This is line 3288 of a file with a large header. # This is line 3289 of a file with a large header. # This is line 3290 of a file with a large header. # This is line 3291 of a file with a large header. # This is line 3292 of a file with a large header. # This is line 3293 of a file with a large header. # This is line 3294 of a file with a large header. # This is line 3295 of a file with a large header. # This is line 3296 of a file with a large header. # This is line 3297 of a file with a large header. # This is line 3298 of a file with a large header. # This is line 3299 of a file with a large header. # This is line 3300 of a file with a large header. # This is line 3301 of a file with a large header. # This is line 3302 of a file with a large header. # This is line 3303 of a file with a large header. # This is line 3304 of a file with a large header. # This is line 3305 of a file with a large header. # This is line 3306 of a file with a large header. # This is line 3307 of a file with a large header. # This is line 3308 of a file with a large header. # This is line 3309 of a file with a large header. # This is line 3310 of a file with a large header. # This is line 3311 of a file with a large header. # This is line 3312 of a file with a large header. # This is line 3313 of a file with a large header. # This is line 3314 of a file with a large header. # This is line 3315 of a file with a large header. # This is line 3316 of a file with a large header. # This is line 3317 of a file with a large header. # This is line 3318 of a file with a large header. # This is line 3319 of a file with a large header. # This is line 3320 of a file with a large header. # This is line 3321 of a file with a large header. # This is line 3322 of a file with a large header. # This is line 3323 of a file with a large header. # This is line 3324 of a file with a large header. # This is line 3325 of a file with a large header. # This is line 3326 of a file with a large header. # This is line 3327 of a file with a large header. # This is line 3328 of a file with a large header. # This is line 3329 of a file with a large header. # This is line 3330 of a file with a large header. # This is line 3331 of a file with a large header. # This is line 3332 of a file with a large header. # This is line 3333 of a file with a large header. # This is line 3334 of a file with a large header. # This is line 3335 of a file with a large header. # This is line 3336 of a file with a large header. # This is line 3337 of a file with a large header. # This is line 3338 of a file with a large header. # This is line 3339 of a file with a large header. # This is line 3340 of a file with a large header. # This is line 3341 of a file with a large header. # This is line 3342 of a file with a large header. # This is line 3343 of a file with a large header. # This is line 3344 of a file with a large header. # This is line 3345 of a file with a large header. # This is line 3346 of a file with a large header. # This is line 3347 of a file with a large header. # This is line 3348 of a file with a large header. # This is line 3349 of a file with a large header. # This is line 3350 of a file with a large header. # This is line 3351 of a file with a large header. # This is line 3352 of a file with a large header. # This is line 3353 of a file with a large header. # This is line 3354 of a file with a large header. # This is line 3355 of a file with a large header. # This is line 3356 of a file with a large header. # This is line 3357 of a file with a large header. # This is line 3358 of a file with a large header. # This is line 3359 of a file with a large header. # This is line 3360 of a file with a large header. # This is line 3361 of a file with a large header. # This is line 3362 of a file with a large header. # This is line 3363 of a file with a large header. # This is line 3364 of a file with a large header. # This is line 3365 of a file with a large header. # This is line 3366 of a file with a large header. # This is line 3367 of a file with a large header. # This is line 3368 of a file with a large header. # This is line 3369 of a file with a large header. # This is line 3370 of a file with a large header. # This is line 3371 of a file with a large header. # This is line 3372 of a file with a large header. # This is line 3373 of a file with a large header. # This is line 3374 of a file with a large header. # This is line 3375 of a file with a large header. # This is line 3376 of a file with a large header. # This is line 3377 of a file with a large header. # This is line 3378 of a file with a large header. # This is line 3379 of a file with a large header. # This is line 3380 of a file with a large header. # This is line 3381 of a file with a large header. # This is line 3382 of a file with a large header. # This is line 3383 of a file with a large header. # This is line 3384 of a file with a large header. # This is line 3385 of a file with a large header. # This is line 3386 of a file with a large header. # This is line 3387 of a file with a large header. # This is line 3388 of a file with a large header. # This is line 3389 of a file with a large header. # This is line 3390 of a file with a large header. # This is line 3391 of a file with a large header. # This is line 3392 of a file with a large header. # This is line 3393 of a file with a large header. # This is line 3394 of a file with a large header. # This is line 3395 of a file with a large header. # This is line 3396 of a file with a large header. # This is line 3397 of a file with a large header. # This is line 3398 of a file with a large header. # This is line 3399 of a file with a large header. # This is line 3400 of a file with a large header. # This is line 3401 of a file with a large header. # This is line 3402 of a file with a large header. # This is line 3403 of a file with a large header. # This is line 3404 of a file with a large header. # This is line 3405 of a file with a large header. # This is line 3406 of a file with a large header. # This is line 3407 of a file with a large header. # This is line 3408 of a file with a large header. # This is line 3409 of a file with a large header. # This is line 3410 of a file with a large header. # This is line 3411 of a file with a large header. # This is line 3412 of a file with a large header. # This is line 3413 of a file with a large header. # This is line 3414 of a file with a large header. # This is line 3415 of a file with a large header. # This is line 3416 of a file with a large header. # This is line 3417 of a file with a large header. # This is line 3418 of a file with a large header. # This is line 3419 of a file with a large header. # This is line 3420 of a file with a large header. # This is line 3421 of a file with a large header. # This is line 3422 of a file with a large header. # This is line 3423 of a file with a large header. # This is line 3424 of a file with a large header. # This is line 3425 of a file with a large header. # This is line 3426 of a file with a large header. # This is line 3427 of a file with a large header. # This is line 3428 of a file with a large header. # This is line 3429 of a file with a large header. # This is line 3430 of a file with a large header. # This is line 3431 of a file with a large header. # This is line 3432 of a file with a large header. # This is line 3433 of a file with a large header. # This is line 3434 of a file with a large header. # This is line 3435 of a file with a large header. # This is line 3436 of a file with a large header. # This is line 3437 of a file with a large header. # This is line 3438 of a file with a large header. # This is line 3439 of a file with a large header. # This is line 3440 of a file with a large header. # This is line 3441 of a file with a large header. # This is line 3442 of a file with a large header. # This is line 3443 of a file with a large header. # This is line 3444 of a file with a large header. # This is line 3445 of a file with a large header. # This is line 3446 of a file with a large header. # This is line 3447 of a file with a large header. # This is line 3448 of a file with a large header. # This is line 3449 of a file with a large header. # This is line 3450 of a file with a large header. # This is line 3451 of a file with a large header. # This is line 3452 of a file with a large header. # This is line 3453 of a file with a large header. # This is line 3454 of a file with a large header. # This is line 3455 of a file with a large header. # This is line 3456 of a file with a large header. # This is line 3457 of a file with a large header. # This is line 3458 of a file with a large header. # This is line 3459 of a file with a large header. # This is line 3460 of a file with a large header. # This is line 3461 of a file with a large header. # This is line 3462 of a file with a large header. # This is line 3463 of a file with a large header. # This is line 3464 of a file with a large header. # This is line 3465 of a file with a large header. # This is line 3466 of a file with a large header. # This is line 3467 of a file with a large header. # This is line 3468 of a file with a large header. # This is line 3469 of a file with a large header. # This is line 3470 of a file with a large header. # This is line 3471 of a file with a large header. # This is line 3472 of a file with a large header. # This is line 3473 of a file with a large header. # This is line 3474 of a file with a large header. # This is line 3475 of a file with a large header. # This is line 3476 of a file with a large header. # This is line 3477 of a file with a large header. # This is line 3478 of a file with a large header. # This is line 3479 of a file with a large header. # This is line 3480 of a file with a large header. # This is line 3481 of a file with a large header. # This is line 3482 of a file with a large header. # This is line 3483 of a file with a large header. # This is line 3484 of a file with a large header. # This is line 3485 of a file with a large header. # This is line 3486 of a file with a large header. # This is line 3487 of a file with a large header. # This is line 3488 of a file with a large header. # This is line 3489 of a file with a large header. # This is line 3490 of a file with a large header. # This is line 3491 of a file with a large header. # This is line 3492 of a file with a large header. # This is line 3493 of a file with a large header. # This is line 3494 of a file with a large header. # This is line 3495 of a file with a large header. # This is line 3496 of a file with a large header. # This is line 3497 of a file with a large header. # This is line 3498 of a file with a large header. # This is line 3499 of a file with a large header. # This is line 3500 of a file with a large header. # This is line 3501 of a file with a large header. # This is line 3502 of a file with a large header. # This is line 3503 of a file with a large header. # This is line 3504 of a file with a large header. # This is line 3505 of a file with a large header. # This is line 3506 of a file with a large header. # This is line 3507 of a file with a large header. # This is line 3508 of a file with a large header. # This is line 3509 of a file with a large header. # This is line 3510 of a file with a large header. # This is line 3511 of a file with a large header. # This is line 3512 of a file with a large header. # This is line 3513 of a file with a large header. # This is line 3514 of a file with a large header. # This is line 3515 of a file with a large header. # This is line 3516 of a file with a large header. # This is line 3517 of a file with a large header. # This is line 3518 of a file with a large header. # This is line 3519 of a file with a large header. # This is line 3520 of a file with a large header. # This is line 3521 of a file with a large header. # This is line 3522 of a file with a large header. # This is line 3523 of a file with a large header. # This is line 3524 of a file with a large header. # This is line 3525 of a file with a large header. # This is line 3526 of a file with a large header. # This is line 3527 of a file with a large header. # This is line 3528 of a file with a large header. # This is line 3529 of a file with a large header. # This is line 3530 of a file with a large header. # This is line 3531 of a file with a large header. # This is line 3532 of a file with a large header. # This is line 3533 of a file with a large header. # This is line 3534 of a file with a large header. # This is line 3535 of a file with a large header. # This is line 3536 of a file with a large header. # This is line 3537 of a file with a large header. # This is line 3538 of a file with a large header. # This is line 3539 of a file with a large header. # This is line 3540 of a file with a large header. # This is line 3541 of a file with a large header. # This is line 3542 of a file with a large header. # This is line 3543 of a file with a large header. # This is line 3544 of a file with a large header. # This is line 3545 of a file with a large header. # This is line 3546 of a file with a large header. # This is line 3547 of a file with a large header. # This is line 3548 of a file with a large header. # This is line 3549 of a file with a large header. # This is line 3550 of a file with a large header. # This is line 3551 of a file with a large header. # This is line 3552 of a file with a large header. # This is line 3553 of a file with a large header. # This is line 3554 of a file with a large header. # This is line 3555 of a file with a large header. # This is line 3556 of a file with a large header. # This is line 3557 of a file with a large header. # This is line 3558 of a file with a large header. # This is line 3559 of a file with a large header. # This is line 3560 of a file with a large header. # This is line 3561 of a file with a large header. # This is line 3562 of a file with a large header. # This is line 3563 of a file with a large header. # This is line 3564 of a file with a large header. # This is line 3565 of a file with a large header. # This is line 3566 of a file with a large header. # This is line 3567 of a file with a large header. # This is line 3568 of a file with a large header. # This is line 3569 of a file with a large header. # This is line 3570 of a file with a large header. # This is line 3571 of a file with a large header. # This is line 3572 of a file with a large header. # This is line 3573 of a file with a large header. # This is line 3574 of a file with a large header. # This is line 3575 of a file with a large header. # This is line 3576 of a file with a large header. # This is line 3577 of a file with a large header. # This is line 3578 of a file with a large header. # This is line 3579 of a file with a large header. # This is line 3580 of a file with a large header. # This is line 3581 of a file with a large header. # This is line 3582 of a file with a large header. # This is line 3583 of a file with a large header. # This is line 3584 of a file with a large header. # This is line 3585 of a file with a large header. # This is line 3586 of a file with a large header. # This is line 3587 of a file with a large header. # This is line 3588 of a file with a large header. # This is line 3589 of a file with a large header. # This is line 3590 of a file with a large header. # This is line 3591 of a file with a large header. # This is line 3592 of a file with a large header. # This is line 3593 of a file with a large header. # This is line 3594 of a file with a large header. # This is line 3595 of a file with a large header. # This is line 3596 of a file with a large header. # This is line 3597 of a file with a large header. # This is line 3598 of a file with a large header. # This is line 3599 of a file with a large header. # This is line 3600 of a file with a large header. # This is line 3601 of a file with a large header. # This is line 3602 of a file with a large header. # This is line 3603 of a file with a large header. # This is line 3604 of a file with a large header. # This is line 3605 of a file with a large header. # This is line 3606 of a file with a large header. # This is line 3607 of a file with a large header. # This is line 3608 of a file with a large header. # This is line 3609 of a file with a large header. # This is line 3610 of a file with a large header. # This is line 3611 of a file with a large header. # This is line 3612 of a file with a large header. # This is line 3613 of a file with a large header. # This is line 3614 of a file with a large header. # This is line 3615 of a file with a large header. # This is line 3616 of a file with a large header. # This is line 3617 of a file with a large header. # This is line 3618 of a file with a large header. # This is line 3619 of a file with a large header. # This is line 3620 of a file with a large header. # This is line 3621 of a file with a large header. # This is line 3622 of a file with a large header. # This is line 3623 of a file with a large header. # This is line 3624 of a file with a large header. # This is line 3625 of a file with a large header. # This is line 3626 of a file with a large header. # This is line 3627 of a file with a large header. # This is line 3628 of a file with a large header. # This is line 3629 of a file with a large header. # This is line 3630 of a file with a large header. # This is line 3631 of a file with a large header. # This is line 3632 of a file with a large header. # This is line 3633 of a file with a large header. # This is line 3634 of a file with a large header. # This is line 3635 of a file with a large header. # This is line 3636 of a file with a large header. # This is line 3637 of a file with a large header. # This is line 3638 of a file with a large header. # This is line 3639 of a file with a large header. # This is line 3640 of a file with a large header. # This is line 3641 of a file with a large header. # This is line 3642 of a file with a large header. # This is line 3643 of a file with a large header. # This is line 3644 of a file with a large header. # This is line 3645 of a file with a large header. # This is line 3646 of a file with a large header. # This is line 3647 of a file with a large header. # This is line 3648 of a file with a large header. # This is line 3649 of a file with a large header. # This is line 3650 of a file with a large header. # This is line 3651 of a file with a large header. # This is line 3652 of a file with a large header. # This is line 3653 of a file with a large header. # This is line 3654 of a file with a large header. # This is line 3655 of a file with a large header. # This is line 3656 of a file with a large header. # This is line 3657 of a file with a large header. # This is line 3658 of a file with a large header. # This is line 3659 of a file with a large header. # This is line 3660 of a file with a large header. # This is line 3661 of a file with a large header. # This is line 3662 of a file with a large header. # This is line 3663 of a file with a large header. # This is line 3664 of a file with a large header. # This is line 3665 of a file with a large header. # This is line 3666 of a file with a large header. # This is line 3667 of a file with a large header. # This is line 3668 of a file with a large header. # This is line 3669 of a file with a large header. # This is line 3670 of a file with a large header. # This is line 3671 of a file with a large header. # This is line 3672 of a file with a large header. # This is line 3673 of a file with a large header. # This is line 3674 of a file with a large header. # This is line 3675 of a file with a large header. # This is line 3676 of a file with a large header. # This is line 3677 of a file with a large header. # This is line 3678 of a file with a large header. # This is line 3679 of a file with a large header. # This is line 3680 of a file with a large header. # This is line 3681 of a file with a large header. # This is line 3682 of a file with a large header. # This is line 3683 of a file with a large header. # This is line 3684 of a file with a large header. # This is line 3685 of a file with a large header. # This is line 3686 of a file with a large header. # This is line 3687 of a file with a large header. # This is line 3688 of a file with a large header. # This is line 3689 of a file with a large header. # This is line 3690 of a file with a large header. # This is line 3691 of a file with a large header. # This is line 3692 of a file with a large header. # This is line 3693 of a file with a large header. # This is line 3694 of a file with a large header. # This is line 3695 of a file with a large header. # This is line 3696 of a file with a large header. # This is line 3697 of a file with a large header. # This is line 3698 of a file with a large header. # This is line 3699 of a file with a large header. # This is line 3700 of a file with a large header. # This is line 3701 of a file with a large header. # This is line 3702 of a file with a large header. # This is line 3703 of a file with a large header. # This is line 3704 of a file with a large header. # This is line 3705 of a file with a large header. # This is line 3706 of a file with a large header. # This is line 3707 of a file with a large header. # This is line 3708 of a file with a large header. # This is line 3709 of a file with a large header. # This is line 3710 of a file with a large header. # This is line 3711 of a file with a large header. # This is line 3712 of a file with a large header. # This is line 3713 of a file with a large header. # This is line 3714 of a file with a large header. # This is line 3715 of a file with a large header. # This is line 3716 of a file with a large header. # This is line 3717 of a file with a large header. # This is line 3718 of a file with a large header. # This is line 3719 of a file with a large header. # This is line 3720 of a file with a large header. # This is line 3721 of a file with a large header. # This is line 3722 of a file with a large header. # This is line 3723 of a file with a large header. # This is line 3724 of a file with a large header. # This is line 3725 of a file with a large header. # This is line 3726 of a file with a large header. # This is line 3727 of a file with a large header. # This is line 3728 of a file with a large header. # This is line 3729 of a file with a large header. # This is line 3730 of a file with a large header. # This is line 3731 of a file with a large header. # This is line 3732 of a file with a large header. # This is line 3733 of a file with a large header. # This is line 3734 of a file with a large header. # This is line 3735 of a file with a large header. # This is line 3736 of a file with a large header. # This is line 3737 of a file with a large header. # This is line 3738 of a file with a large header. # This is line 3739 of a file with a large header. # This is line 3740 of a file with a large header. # This is line 3741 of a file with a large header. # This is line 3742 of a file with a large header. # This is line 3743 of a file with a large header. # This is line 3744 of a file with a large header. # This is line 3745 of a file with a large header. # This is line 3746 of a file with a large header. # This is line 3747 of a file with a large header. # This is line 3748 of a file with a large header. # This is line 3749 of a file with a large header. # This is line 3750 of a file with a large header. # This is line 3751 of a file with a large header. # This is line 3752 of a file with a large header. # This is line 3753 of a file with a large header. # This is line 3754 of a file with a large header. # This is line 3755 of a file with a large header. # This is line 3756 of a file with a large header. # This is line 3757 of a file with a large header. # This is line 3758 of a file with a large header. # This is line 3759 of a file with a large header. # This is line 3760 of a file with a large header. # This is line 3761 of a file with a large header. # This is line 3762 of a file with a large header. # This is line 3763 of a file with a large header. # This is line 3764 of a file with a large header. # This is line 3765 of a file with a large header. # This is line 3766 of a file with a large header. # This is line 3767 of a file with a large header. # This is line 3768 of a file with a large header. # This is line 3769 of a file with a large header. # This is line 3770 of a file with a large header. # This is line 3771 of a file with a large header. # This is line 3772 of a file with a large header. # This is line 3773 of a file with a large header. # This is line 3774 of a file with a large header. # This is line 3775 of a file with a large header. # This is line 3776 of a file with a large header. # This is line 3777 of a file with a large header. # This is line 3778 of a file with a large header. # This is line 3779 of a file with a large header. # This is line 3780 of a file with a large header. # This is line 3781 of a file with a large header. # This is line 3782 of a file with a large header. # This is line 3783 of a file with a large header. # This is line 3784 of a file with a large header. # This is line 3785 of a file with a large header. # This is line 3786 of a file with a large header. # This is line 3787 of a file with a large header. # This is line 3788 of a file with a large header. # This is line 3789 of a file with a large header. # This is line 3790 of a file with a large header. # This is line 3791 of a file with a large header. # This is line 3792 of a file with a large header. # This is line 3793 of a file with a large header. # This is line 3794 of a file with a large header. # This is line 3795 of a file with a large header. # This is line 3796 of a file with a large header. # This is line 3797 of a file with a large header. # This is line 3798 of a file with a large header. # This is line 3799 of a file with a large header. # This is line 3800 of a file with a large header. # This is line 3801 of a file with a large header. # This is line 3802 of a file with a large header. # This is line 3803 of a file with a large header. # This is line 3804 of a file with a large header. # This is line 3805 of a file with a large header. # This is line 3806 of a file with a large header. # This is line 3807 of a file with a large header. # This is line 3808 of a file with a large header. # This is line 3809 of a file with a large header. # This is line 3810 of a file with a large header. # This is line 3811 of a file with a large header. # This is line 3812 of a file with a large header. # This is line 3813 of a file with a large header. # This is line 3814 of a file with a large header. # This is line 3815 of a file with a large header. # This is line 3816 of a file with a large header. # This is line 3817 of a file with a large header. # This is line 3818 of a file with a large header. # This is line 3819 of a file with a large header. # This is line 3820 of a file with a large header. # This is line 3821 of a file with a large header. # This is line 3822 of a file with a large header. # This is line 3823 of a file with a large header. # This is line 3824 of a file with a large header. # This is line 3825 of a file with a large header. # This is line 3826 of a file with a large header. # This is line 3827 of a file with a large header. # This is line 3828 of a file with a large header. # This is line 3829 of a file with a large header. # This is line 3830 of a file with a large header. # This is line 3831 of a file with a large header. # This is line 3832 of a file with a large header. # This is line 3833 of a file with a large header. # This is line 3834 of a file with a large header. # This is line 3835 of a file with a large header. # This is line 3836 of a file with a large header. # This is line 3837 of a file with a large header. # This is line 3838 of a file with a large header. # This is line 3839 of a file with a large header. # This is line 3840 of a file with a large header. # This is line 3841 of a file with a large header. # This is line 3842 of a file with a large header. # This is line 3843 of a file with a large header. # This is line 3844 of a file with a large header. # This is line 3845 of a file with a large header. # This is line 3846 of a file with a large header. # This is line 3847 of a file with a large header. # This is line 3848 of a file with a large header. # This is line 3849 of a file with a large header. # This is line 3850 of a file with a large header. # This is line 3851 of a file with a large header. # This is line 3852 of a file with a large header. # This is line 3853 of a file with a large header. # This is line 3854 of a file with a large header. # This is line 3855 of a file with a large header. # This is line 3856 of a file with a large header. # This is line 3857 of a file with a large header. # This is line 3858 of a file with a large header. # This is line 3859 of a file with a large header. # This is line 3860 of a file with a large header. # This is line 3861 of a file with a large header. # This is line 3862 of a file with a large header. # This is line 3863 of a file with a large header. # This is line 3864 of a file with a large header. # This is line 3865 of a file with a large header. # This is line 3866 of a file with a large header. # This is line 3867 of a file with a large header. # This is line 3868 of a file with a large header. # This is line 3869 of a file with a large header. # This is line 3870 of a file with a large header. # This is line 3871 of a file with a large header. # This is line 3872 of a file with a large header. # This is line 3873 of a file with a large header. # This is line 3874 of a file with a large header. # This is line 3875 of a file with a large header. # This is line 3876 of a file with a large header. # This is line 3877 of a file with a large header. # This is line 3878 of a file with a large header. # This is line 3879 of a file with a large header. # This is line 3880 of a file with a large header. # This is line 3881 of a file with a large header. # This is line 3882 of a file with a large header. # This is line 3883 of a file with a large header. # This is line 3884 of a file with a large header. # This is line 3885 of a file with a large header. # This is line 3886 of a file with a large header. # This is line 3887 of a file with a large header. # This is line 3888 of a file with a large header. # This is line 3889 of a file with a large header. # This is line 3890 of a file with a large header. # This is line 3891 of a file with a large header. # This is line 3892 of a file with a large header. # This is line 3893 of a file with a large header. # This is line 3894 of a file with a large header. # This is line 3895 of a file with a large header. # This is line 3896 of a file with a large header. # This is line 3897 of a file with a large header. # This is line 3898 of a file with a large header. # This is line 3899 of a file with a large header. # This is line 3900 of a file with a large header. # This is line 3901 of a file with a large header. # This is line 3902 of a file with a large header. # This is line 3903 of a file with a large header. # This is line 3904 of a file with a large header. # This is line 3905 of a file with a large header. # This is line 3906 of a file with a large header. # This is line 3907 of a file with a large header. # This is line 3908 of a file with a large header. # This is line 3909 of a file with a large header. # This is line 3910 of a file with a large header. # This is line 3911 of a file with a large header. # This is line 3912 of a file with a large header. # This is line 3913 of a file with a large header. # This is line 3914 of a file with a large header. # This is line 3915 of a file with a large header. # This is line 3916 of a file with a large header. # This is line 3917 of a file with a large header. # This is line 3918 of a file with a large header. # This is line 3919 of a file with a large header. # This is line 3920 of a file with a large header. # This is line 3921 of a file with a large header. # This is line 3922 of a file with a large header. # This is line 3923 of a file with a large header. # This is line 3924 of a file with a large header. # This is line 3925 of a file with a large header. # This is line 3926 of a file with a large header. # This is line 3927 of a file with a large header. # This is line 3928 of a file with a large header. # This is line 3929 of a file with a large header. # This is line 3930 of a file with a large header. # This is line 3931 of a file with a large header. # This is line 3932 of a file with a large header. # This is line 3933 of a file with a large header. # This is line 3934 of a file with a large header. # This is line 3935 of a file with a large header. # This is line 3936 of a file with a large header. # This is line 3937 of a file with a large header. # This is line 3938 of a file with a large header. # This is line 3939 of a file with a large header. # This is line 3940 of a file with a large header. # This is line 3941 of a file with a large header. # This is line 3942 of a file with a large header. # This is line 3943 of a file with a large header. # This is line 3944 of a file with a large header. # This is line 3945 of a file with a large header. # This is line 3946 of a file with a large header. # This is line 3947 of a file with a large header. # This is line 3948 of a file with a large header. # This is line 3949 of a file with a large header. # This is line 3950 of a file with a large header. # This is line 3951 of a file with a large header. # This is line 3952 of a file with a large header. # This is line 3953 of a file with a large header. # This is line 3954 of a file with a large header. # This is line 3955 of a file with a large header. # This is line 3956 of a file with a large header. # This is line 3957 of a file with a large header. # This is line 3958 of a file with a large header. # This is line 3959 of a file with a large header. # This is line 3960 of a file with a large header. # This is line 3961 of a file with a large header. # This is line 3962 of a file with a large header. # This is line 3963 of a file with a large header. # This is line 3964 of a file with a large header. # This is line 3965 of a file with a large header. # This is line 3966 of a file with a large header. # This is line 3967 of a file with a large header. # This is line 3968 of a file with a large header. # This is line 3969 of a file with a large header. # This is line 3970 of a file with a large header. # This is line 3971 of a file with a large header. # This is line 3972 of a file with a large header. # This is line 3973 of a file with a large header. # This is line 3974 of a file with a large header. # This is line 3975 of a file with a large header. # This is line 3976 of a file with a large header. # This is line 3977 of a file with a large header. # This is line 3978 of a file with a large header. # This is line 3979 of a file with a large header. # This is line 3980 of a file with a large header. # This is line 3981 of a file with a large header. # This is line 3982 of a file with a large header. # This is line 3983 of a file with a large header. # This is line 3984 of a file with a large header. # This is line 3985 of a file with a large header. # This is line 3986 of a file with a large header. # This is line 3987 of a file with a large header. # This is line 3988 of a file with a large header. # This is line 3989 of a file with a large header. # This is line 3990 of a file with a large header. # This is line 3991 of a file with a large header. # This is line 3992 of a file with a large header. # This is line 3993 of a file with a large header. # This is line 3994 of a file with a large header. # This is line 3995 of a file with a large header. # This is line 3996 of a file with a large header. # This is line 3997 of a file with a large header. # This is line 3998 of a file with a large header. # This is line 3999 of a file with a large header. chr1 100 101 a2 2 - chr1 100 110 a2 2 - chr1 10 60 three_blocks_nomatch 0 + 0 0 0 3 10,10,10, 0,20,40, chr1 10 20 chr1 10 20 345.7 why? ##fileformat=VCFv4.1 chr1 5 a G 70.90 . TOOL=LUMPY;SVTYPE=DEL;SVLEN=500;END=253195;STR=+-:4;IMPRECISE;CIPOS=-2,137;CIEND=0,0;EVENT=791255;SUP=4;PESUP=4;SRSUP=0;EV=PE;PRIN;CSQ=intergenic_variant|||||||||| chr1 15 a G 70.90 . TOOL=LUMPY;SVTYPE=DEL;SVLEN=-600;END=253195;STR=+-:4;IMPRECISE;CIPOS=-2,137;CIEND=0,0;EVENT=791255;SUP=4;PESUP=4;SRSUP=0;EV=PE;PRIN;CSQ=intergenic_variant|||||||||| chr1 10 20 a1 100 + chr2 10 20 a2 100 + chr10 10 20 a3 100 + chr11 10 20 a4 100 + chrX 10 20 a5 100 + chrM 10 20 a6 100 + ##fileformat=VCFv4.1 chr1 5 a G 70.90 . TOOL=LUMPY;SVTYPE=DEL;SVLEN=500;END=253195;STR=+-:4;IMPRECISE;CIPOS=-2,137;CIEND=0,0;EVENT=791255;SUP=4;PESUP=4;SRSUP=0;EV=PE;PRIN;CSQ=intergenic_variant|||||||||| chr1 15 a G 70.90 . TOOL=LUMPY;SVTYPE=DEL;SVLEN=-600;END=253195;STR=+-:4;IMPRECISE;CIPOS=-2,137;CIEND=0,0;EVENT=791255;SUP=4;PESUP=4;SRSUP=0;EV=PE;PRIN;CSQ=intergenic_variant|||||||||| chr1 25 c T 71.90 . TOOL=LUMPY;SVTYPE=DEL;END=253195;STR=+-:4;IMPRECISE;CIPOS=-2,137;CIEND=0,0;EVENT=791255;SUP=4;PESUP=4;SRSUP=0;EV=PE;PRIN;CSQ=intergenic_variant||||||||||;SVLEN=-600 @HD VN:1.0 GO:none SO:coordinate @SQ SN:chr1 LN:249250621 two_blocks 16 chr1 1 40 15M10N15M * 0 0 GAAGGCCACCGCCGCGGTTATTTTCCTTCA CCCDDB?=FJIIJIGFJIJHIJJJJJJJJI MD:Z:50GL000194.1 48590 120018 ensembl 999 - GL000194.1 48594 120055 ensembl 999 - BC4sred)E I2aCBCϏ43, U&#E9mvJ aV nF9DN 睔vY^cvZUr7eby.N̻)2ק ?++zU-r ړnؾX *PZ)02?))]fR8!SHH!).ا㕌I7&%uR9_M4bq0;26MU:B(E;(sHGD{B^fRz*$SOB8QhD#?`7nK>}i@v6婩=R *5Z5A@g7Eѷ7@^W7hg@ SR8Rgf@(x gz}Av6TS꺎1 պ^0`e݅!e+HBǑo<+jƘjrF92(gPH { 4"]?Qt|CؐH\vO^ ~x JHm1=Q7uڡa zC 7a:BCd. f)?R ! ufpfjvkCCb4+*ay1=kD%fGG{UlnD]BCchr1 5 15 r1 chr1 7 12 r3 chr1 20 25 r2 BCp Mj&ѹW!Q}xv6 ޾ԃ;z鐙?|~o?}>o/^X &m9rhΡCKNYҩSKN-Z:tj饥^k[K/-KK/-[Ko-/Zzk魥Zh飥>Z1-}GK-}WK_-}Zj髥.-]ZtiҥҥKKn-ZtkҭҭGK-=Zzhң 哛˸Y0Y0Y0Y0Y0 Z0Z0+Z0;Z0KZ0[Z0kZ0{Z0Z0Z0Z0Z0Z0Z0Z0Z0 [0[0+[0;[0K[0[[0k[0{[0[0[0[0[0[0[0[0[0 \0\0+\0;\%;\%;\%;\%;\%;\%;\%;\%;\%;\å߿7}6nMl~lppppppppppppppppppppppppppppppppppppn-v;b[pn-v;b[pn-v;b[pn-v?Qꏔ3_xc\?XOpn-v;b[pn-v;b[pn-v;b[pn-v;b[pn-v;b[pn-v;b[pn-v;b[pn-v6;fpnmv6;fpnmv6;fpnmv6;fpnmv6;fpnmvx[5o_x77]o7v6;fpnmv6;fpnmv6;fpnmv6;fpnmv6;fpnmv6;fpnmv;a;pvw;a;pvw;a;pvw;a;pvw;a;pvw;a;pvw;S?w^p7?~vw;a;pvw;a;pvw;a;pvw;a;pvw;a;p]vw.;ep]vw.;ep]vw.;ep]vw.;ep]vw.;ep]vw.;ep]vw.;ep]vwT?OBP,T? rs?Dep]vw.;ep]vw.;ep]vw.;ep]vwnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnn!Mh7oD˿m&M>ܛx}F7ro3ͽg{<&^M>ݛx}F7to3սg{\&^M>ݛx}F7vo3ݽg{|&^M>ޛx}F7xo3彉g{Ϝ&^AM>ޛx}F7zo3g{ϼ&^M>ߛx}F7|o3 p p p p p p p p p p p p p p p p p p p p p p p p p p p p p p p p p p p p p p p p p p p p p p p p p pKtKtKtKtKtKtKtKtKtKtKtKtKtKtKtKtKtKtKtKtKtKtKtKtKtKtKtKtKtKtKtKtKtKtKtKtKtKtKtKtKtKtKtKtKtKtKtKtKtKt[n}˭o-ַ֟XUbBC+ M&Hѹ\̌} VpZ8gv~|o׻_?k|뷯o_?\ O''I}}_^?~x^?~xO^?~z/_^~yo^~{o^{^{^{?^x?^x?^z׿^z׿^z?^xׯׯׯׯׯׯׯ/r+r+r+r+r+r+r+r+r+r+r+r+r+r+r+r+r+r+r+r+r+r+r+r+r+r+r+r+r+r+r+r+r+r+r+r+r+r+r+r+r+r+r+r+r+r+vkvkvkvkvkvkvkvkvkvkvkvkvkvkvkvkvkvkvkvkvkvkvkvkvkvkvkvkvkvkvkvkvkvkvkvkvkvkvkvkvkvkvkvkvkvkvkvkvkvkַ[vn}ۭomַ[vn}ۭomַ[vn}ۭomַ[vn}ۭomַ[vn}ۭomַ[vn}ۭomַ[vn}ۭomַ[vn}ۭomַ[vn}ۭomַ[vn}ۭomַ[vn}ۭomַ[vn}ۭomַ[v;n}ǭw[q;n}ǭw[q;n}ǭw[q;n}ǭw[q;n}ǭw[q;n}ǭw[q;n}ǭw[q;n}ǭw[q;n}ǭw[q;n}ǭw[q;n}ǭw[q;n}ǭw[q;n}ǭw[un}׭]w[un}׭]w[un}׭]w[un}׭]w[un}׭]w[un}׭]w[un}׭]w[un}׭]w[un}׭]w[un}׭]w[un}׭]w[un}׭]w[uqqqqqqqqqqqqqqqqqqqqqqqqqqqqqqqqqqqqqqqqqqqqqqqqqa[ߛh7oD뿉&ZMx}7l}og{&^M>[ߛx}7l}og{&^M>[ߛx}7l}og{&^M>[ߛx}7l}og{&^M>[ߛx}7l}og{&^M>[ߛx}7l}og{[r[n}˭o-ַ[r[n}˭o-ַ[r[n}˭o-ַ[r[n}˭o-ַ[r[n}˭o-ַ[r[n}˭o-ַ[r[n}˭o-ַ[r[n}˭o-ַ[r[n}˭o-ַ[r[n}˭o-ַ[r[n}˭o-ַ[r[n}˭o-ַ[r[n}n}n}n}n}n}n}n}n}n}n}n}n}n}n}n}n}n}n}n}n}n}n}n}n}n}n}n}n}n}n}n}n}n}n}n}n}n}n}n}n}n}n}n}n}n}n}n}n}n}n}֗n}֗n}֗n}֗n}֗n}֗n}֗n}֗n}֗n}֗n}֗n}֗n}֗n}֗n}֗n}֗n}֗n}֗n}֗n}֗n}֗n}֗n}֗n}֗n}֗n}֗n}֗n}֗n}֗n}֗n}֗n}֗n}֗n}֗n}֗n}֗n}֗n}֗n}֗n}֗n}֗n}֗n}֗n}֗n}֗n}֗n}֗n}֗n}֗n}֗n}Wn}Wn}Wn}Wn}Wn}Wn}Wn}Wn}Wn}Wn}Wn}Wn}Wn}Wn}Wn}Wn}Wn}Wn}Wn}Wn}Wn}Wn}Wn}Wn}Wn}Wn}Wn}Wn}Wn}Wn}Wn}Wn}Wn}Wn}Wn}Wn}Wn}Wn}Wn}Wn}Wn}Wn}Wn}Wn}Wn}Wn}Wn}Wn}Wn}Wn}n}n}n}n}n}n}n}n}n}n}n}n}n}n}n}n}n}n}n}n}n}n}n}n}n}n}n}n}n}n}n}n}n}n}n}n}n}n}n}n}n}n}n}n}n}f}X~BC+ MYRѾ`_Ύe& & y[Oo??׿_Q/~~oL''d}t??>9>?\~x?^x?^x^?~x^?~zO^?~z׿^z׿^z/_^~y/_^~{o^~{?^x_^z^y}vkvkvkvqqqqqqqqqqqqqqqqqqqqqqqqqqqqqqqqqqqqqqqqqqqqqqqqqq[u[u[u[u[u[u[u[u[u[u[u[u[u[u[u[u[u[u[u[u[u[u[u[u[u[u[u[u[u[u[u[u[u[u[u[u[u[u[u[u[u[u[u[u[u[u[u[u[u[u{n}ϭ=[s{n}ϭ=[s{n}ϭ=[s{n}ϭ=[s{n}ϭ=[s{n}ϭ=[s{n}ϭ=[s{n}ϭ=[s{n}ϭ=[s{n}ϭ=[s{n}ϭ=[s{n}ϭ=[s{n}ϭ=a&Zho&Zho&^x}og&^x}og&^x}og&^x}og&^x}og&^x}og&^x}og&^x}og&^x}og&^x}og&^x}og&^pw[q;n}ǭw[q;n}ǭw[q;n}ǭw[q;n}ǭw[q;n}ǭw[q;n}ǭw[q;n}ǭw[q;n}ǭw[q;n}ǭw[q;n}ǭw[q;n}ǭw[q;n}ǭw[q p p p p p p p p p p p p p p p p p p p p p p p p p p p p p p p p p p p p p p p p p p p p p p p p p pKtKtKtKtKtKtKtKtKtKtKtKtKtKtKtKtKtKtKtKtKtKtKtKtKtKtKtKtKtKtKtKtKtKtKtKtKtKtKtKtKtKtKtKtKtKtKtKtKtKtn}׭]w[un}׭]w[un}׭]w[un}׭]w[un}׭]w[un}׭]w[un}׭]w[un}׭]w[un}׭]w[un}׭]w[un}׭]w[un}׭]w[un}׭]r+r+r+r+r+r+r+r+r+r+r+r+r+r+r+r+r+r+r+r+r+r+r+r+r+r+r+r+r+r+r+r+r+r+r+r+r+r+r+r+r+r+r+r+r+r+r+r+r+r+vkvkvkvkvkvkvkvkvkvkvkvkvkvkvkvkvkvkvkvkvkvkvkvkvkvkvkvkvkvkvkvkvkvkvkvkvkvkvkvkvkvkvkvkvkvkvkvkvkvkqqqqqqqqqqqqqqqqqqqqqqqqqqqqqqqqqqqqqqqqqqqqqqqqqqu[u[u[u[u[u[u[u[u[u[u[u[u[u[u[u[u[u[u[u[u[u[u[u[u[u[u[u[u[u[u[u[u[u[u[u[u[u[? @GBCKSQQ\)yy8) QpƆ͢Xpvkz9<>|ؿ\o~\~:~_oϏ'ɩdddOr~\?׏q~X?SX?SX?SX?SX?S\~uWׯ_]~u7o\~sw]~ww?\p?\tOן?]t/_\r?\p?\p}o}o}o}o}o}o}o}o}o}o}o}֗[nllgm^)BCchr1 0 45 three_blocks_match 0 + 0 0 0 2 5,10, 25,35, chr2L . UTR 41 70 0 + . ID=mRNA:xs2:UTR:41-70;Parent=mRNA:xs2; chr2L . CDS 71 130 0 + . ID=mRNA:xs2:CDS:71-130;Parent=mRNA:xs2; chr2L . intron 131 170 0 + . ID=mRNA:xs2:intron:131-170;Parent=mRNA:xs2; chr2L . CDS 171 200 0 + . ID=mRNA:xs2:CDS:171-200;Parent=mRNA:xs2; chr2L . UTR 201 220 0 + . ID=mRNA:xs2:UTR:201-220;Parent=mRNA:xs2; chr2L . exon 41 130 0 + . ID=mRNA:xs2:exon:41-130;Parent=mRNA:xs2; chr2L . exon 171 220 0 + . ID=mRNA:xs2:exon:171-220;Parent=mRNA:xs2; chr2L . mRNA 41 220 0 + . ID=mRNA:xs2;Parent=g2; chr2L . CDS 161 230 0 - . ID=tRNA:t2:CDS:161-230;Parent=tRNA:t2; chr2L . exon 161 230 0 - . ID=tRNA:t2:exon:161-230;Parent=tRNA:t2; chr2L . tRNA 161 230 0 - . ID=tRNA:t2;Parent=t2; chr2L . gene 41 220 0 + . ID=g2; ################################################################# # # PERFORMANCE TESTS FOR VARIOUS INPUT METHODS. # # We'll test uncompressed data, gzip, bgzip, and Bam files. # Each will be tried as a file, and as the 3 types of stdin: # redirects, pipes, and fifos. # # We'll run each one twice in a row to check for improvement # due to a cache warm up. # ################################################################# BT=${BT-../../bin/bedtools} ################################################################# # Start by generating data, if desired # ################################################################# if true; then echo "generating data..." mkdir perfData cd perfData ../$BT random -l 1000 -n 10000000 -g ../human.hg19.genome | sort -k1,1 -k2,2n > a10M.bed ../$BT random -l 1000 -n 10000000 -g ../human.hg19.genome | sort -k1,1 -k2,2n > b10M.bed cp a10M.bed a10M_gzipped.bed gzip a10M_gzipped.bed ../../htsutil bgzfcompress a10M.bed a10M_bgzipped.bed.gz ../$BT bedtobam -i a10M.bed -g ../human.hg19.genome > a10M.bam cd .. fi ################################################################### # Begin Tests ################################################################### echo -e "Test 1 of 16...." echo "Test 1: Intersect a10M, ten million records, uncompressed from file with b10M" > runLog.txt runit $BT intersect -a perfData/a10M.bed -b perfData/b10M.bed -sorted 2>&1 >/dev/null | grep -e "user" -e maxrss >> runLog.txt echo -e "\nRe-do test 1 for possible cache speed up." >> runLog.txt runit $BT intersect -a perfData/a10M.bed -b perfData/b10M.bed -sorted 2>&1 >/dev/null | grep -e "user" -e maxrss >> runLog.txt echo -e "Test 2 of 16...." echo -e "\n\nTest 2: Intersect a10M, ten million records, gzipped from file with b10M" >> runLog.txt runit $BT intersect -a perfData/a10M_gzipped.bed.gz -b perfData/b10M.bed -sorted 2>&1 >/dev/null | grep -e "user" -e maxrss >> runLog.txt echo -e "\nRe-do test 2 for possible cache speed up." >> runLog.txt runit $BT intersect -a perfData/a10M_gzipped.bed.gz -b perfData/b10M.bed -sorted 2>&1 >/dev/null | grep -e "user" -e maxrss >> runLog.txt echo -e "Test 3 of 16...." echo -e "\n\nTest 3: Intersect a10M, ten million records, bgzipped from file with b10M" >> runLog.txt runit $BT intersect -a perfData/a10M_bgzipped.bed.gz -b perfData/b10M.bed -sorted 2>&1 >/dev/null | grep -e "user" -e maxrss >> runLog.txt echo -e "\nRe-do test 3 for possible cache speed up." >> runLog.txt runit $BT intersect -a perfData/a10M_bgzipped.bed.gz -b perfData/b10M.bed -sorted 2>&1 >/dev/null | grep -e "user" -e maxrss >> runLog.txt echo -e "Test 4 of 16...." echo -e "\n\nTest 4: Intersect a10M, ten million records, bam from file with b10M" >> runLog.txt runit $BT intersect -a perfData/a10M.bam -b perfData/b10M.bed -sorted 2>&1 >/dev/null | grep -e "user" -e maxrss >> runLog.txt echo -e "\nRe-do test 4 for possible cache speed up." >> runLog.txt runit $BT intersect -a perfData/a10M.bam -b perfData/b10M.bed -sorted 2>&1 >/dev/null | grep -e "user" -e maxrss >> runLog.txt echo -e "Test 5 of 16...." echo -e "\n\nTest 5: Intersect a10M, ten million records, uncompressed from redirect with b10M" >> runLog.txt runit $BT intersect -a - -b perfData/b10M.bed -sorted < perfData/a10M.bed 2>&1 >/dev/null | grep -e "user" -e maxrss >> runLog.txt echo -e "\nRe-do test 5 for possible cache speed up." >> runLog.txt runit $BT intersect -a - -b perfData/b10M.bed -sorted < perfData/a10M.bed 2>&1 >/dev/null | grep -e "user" -e maxrss >> runLog.txt echo -e "Test 6 of 16...." echo -e "\n\nTest 6: Intersect a10M, ten million records, gzipped from redirect with b10M" >> runLog.txt runit $BT intersect -a - -b perfData/b10M.bed -sorted < perfData/a10M_gzipped.bed.gz 2>&1 >/dev/null | grep -e "user" -e maxrss >> runLog.txt echo -e "\nRe-do test 6 for possible cache speed up." >> runLog.txt runit $BT intersect -a - -b perfData/b10M.bed -sorted < perfData/a10M_gzipped.bed.gz 2>&1 >/dev/null | grep -e "user" -e maxrss >> runLog.txt echo -e "Test 7 of 16...." echo -e "\n\nTest 7: Intersect a10M, ten million records, bgzipped from redirect with b10M" >> runLog.txt runit $BT intersect -a - -b perfData/b10M.bed -sorted < perfData/a10M_bgzipped.bed.gz 2>&1 >/dev/null | grep -e "user" -e maxrss >> runLog.txt echo -e "\nRe-do test 7 for possible cache speed up." >> runLog.txt runit $BT intersect -a - -b perfData/b10M.bed -sorted < perfData/a10M_bgzipped.bed.gz 2>&1 >/dev/null | grep -e "user" -e maxrss >> runLog.txt echo -e "Test 8 of 16...." echo -e "\n\nTest 8: Intersect a10M, ten million records, bam from redirect with b10M" >> runLog.txt runit $BT intersect -a - -b perfData/b10M.bed -sorted < perfData/a10M.bam 2>&1 >/dev/null | grep -e "user" -e maxrss >> runLog.txt echo -e "\nRe-do test 8 for possible cache speed up." >> runLog.txt runit $BT intersect -a - -b perfData/b10M.bed -sorted < perfData/a10M.bam 2>&1 >/dev/null | grep -e "user" -e maxrss >> runLog.txt echo -e "Test 9 of 16...." echo -e "\n\nTest 9: Intersect a10M, ten million records, uncompressed from pipe with b10M" >> runLog.txt cat perfData/a10M.bed | runit $BT intersect -a - -b perfData/b10M.bed -sorted 2>&1 >/dev/null | grep -e "user" -e maxrss >> runLog.txt echo -e "\nRe-do test 9 for possible cache speed up." >> runLog.txt cat perfData/a10M.bed | runit $BT intersect -a - -b perfData/b10M.bed -sorted 2>&1 >/dev/null | grep -e "user" -e maxrss >> runLog.txt echo -e "Test 10 of 16...." echo -e "\n\nTest 10: Intersect a10M, ten million records, gzip from pipe with b10M" >> runLog.txt cat perfData/a10M_gzipped.bed.gz | runit $BT intersect -a - -b perfData/b10M.bed -sorted 2>&1 >/dev/null | grep -e "user" -e maxrss >> runLog.txt echo -e "\nRe-do test 10 for possible cache speed up." >> runLog.txt cat perfData/a10M_gzipped.bed.gz | runit $BT intersect -a - -b perfData/b10M.bed -sorted 2>&1 >/dev/null | grep -e "user" -e maxrss >> runLog.txt echo -e "Test 11 of 16...." echo -e "\n\nTest 11: Intersect a10M, ten million records, bgzip from pipe with b10M" >> runLog.txt cat perfData/a10M_bgzipped.bed.gz | runit $BT intersect -a - -b perfData/b10M.bed -sorted 2>&1 >/dev/null | grep -e "user" -e maxrss >> runLog.txt echo -e "\nRe-do test 11 for possible cache speed up." >> runLog.txt cat perfData/a10M_bgzipped.bed.gz | runit $BT intersect -a - -b perfData/b10M.bed -sorted 2>&1 >/dev/null | grep -e "user" -e maxrss >> runLog.txt echo -e "Test 12 of 16...." echo -e "\n\nTest 12: Intersect a10M, ten million records, bam from pipe with b10M" >> runLog.txt cat perfData/a10M.bam | runit $BT intersect -a - -b perfData/b10M.bed -sorted 2>&1 >/dev/null | grep -e "user" -e maxrss >> runLog.txt echo -e "\nRe-do test 12 for possible cache speed up." >> runLog.txt cat perfData/a10M.bam | runit $BT intersect -a - -b perfData/b10M.bed -sorted 2>&1 >/dev/null | grep -e "user" -e maxrss >> runLog.txt echo -e "Test 13 of 16...." echo -e "\n\nTest 13: Intersect a10M, ten million records, uncompressed from fifo with b10M" >> runLog.txt runit $BT intersect -a <(cat perfData/a10M.bed) -b perfData/b10M.bed -sorted 2>&1 >/dev/null | grep -e "user" -e maxrss >> runLog.txt echo -e "\nRe-do test 13 for possible cache speed up." >> runLog.txt runit $BT intersect -a <(cat perfData/a10M.bed) -b perfData/b10M.bed -sorted 2>&1 >/dev/null | grep -e "user" -e maxrss >> runLog.txt echo -e "Test 14 of 16...." echo -e "\n\nTest 14: Intersect a10M, ten million records, gzipped from fifo with b10M" >> runLog.txt runit $BT intersect -a <(cat perfData/a10M_gzipped.bed.gz) -b perfData/b10M.bed -sorted 2>&1 >/dev/null | grep -e "user" -e maxrss >> runLog.txt echo -e "\nRe-do test 14 for possible cache speed up." >> runLog.txt runit $BT intersect -a <(cat perfData/a10M_gzipped.bed.gz) -b perfData/b10M.bed -sorted 2>&1 >/dev/null | grep -e "user" -e maxrss >> runLog.txt echo -e "Test 15 of 16...." echo -e "\n\nTest 15: Intersect a10M, ten million records, bgzipped from fifo with b10M" >> runLog.txt runit $BT intersect -a <(cat perfData/a10M_bgzipped.bed.gz) -b perfData/b10M.bed -sorted 2>&1 >/dev/null | grep -e "user" -e maxrss >> runLog.txt echo -e "\nRe-do test 15 for possible cache speed up." >> runLog.txt runit $BT intersect -a <(cat perfData/a10M_bgzipped.bed.gz) -b perfData/b10M.bed -sorted 2>&1 >/dev/null | grep -e "user" -e maxrss >> runLog.txt echo -e "Test 16 of 16...." echo -e "\n\nTest 16: Intersect a10M, ten million records, bam from fifo with b10M" >> runLog.txt runit $BT intersect -a <(cat perfData/a10M.bam) -b perfData/b10M.bed -sorted 2>&1 >/dev/null | grep -e "user" -e maxrss >> runLog.txt echo -e "\nRe-do test 16 for possible cache speed up." >> runLog.txt runit $BT intersect -a <(cat perfData/a10M.bam) -b perfData/b10M.bed -sorted 2>&1 >/dev/null | grep -e "user" -e maxrss >> runLog.txt echo "Tests completed." rm -rf perfData chr1 10 20 chr1 80 100 chr2 50 80 chr2 100 120 chr10 5 50 chr10 80 120 chr11 20 60 chr11 80 120 chr12 10 50 chr12 60 90 chr1_gl0003 20 80 chr01 10 20 chr01 80 100 chr02 50 80 chr02 100 120 chr010 5 50 chr010 80 120 chr011 20 60 chr011 80 120 chr012 10 50 chr012 60 90 chr1 10 20 chr1 80 100 chr2 50 80 chr2 100 120 chr3 5 10 chr10 5 50 chr10 80 120 chr11 20 60 chr11 80 120 chr12 10 50 chr12 60 90 chr1 10 20 chr11 10 20 chr3 10 20 chr12 10 20 chr2 10 20 chr1 10 20 chr1 80 100 chr3 60 100 chr3 90 150 chr12 10 50 chr12 60 90 chr1 10 20 chr10 10 20 chr11 10 20 chr12 10 20 chr2 10 20 chr1 10 20 chr1 80 100 chr2 50 80 chr2 100 120 chr10 5 50 chr10 80 120 chr11 20 60 chr11 80 120 chr12 10 50 chr12 60 90 chr2 50 80 chr2 100 120 chr3 20 70 chr3 50 100 chr11 20 60 chr11 80 120 ERROR: chromomsome sort ordering for file sdb1.bed is inconsistent with other files. Record was: chr2 10 20 chr2 10 20 chr12 10 20 chr1 10 20 chr1 80 100 2 50 80 2 100 120 chr10 5 50 chr10 80 120 chr11 20 60 chr11 80 120 chr12 10 50 chr12 60 90 chr1 10 20 chr2 10 20 chr10 10 20 chr11 10 20 chr12 10 20 chr12 10 50 chr12 60 90 chr3 60 100 chr3 90 150 chr1 10 20 chr1 80 100 chr1 10 20 chr3 10 20 chr11 10 20 54d53 < chr1 10346493 10346588 419771 100 + 63d61 < chr1 12637536 12637591 487117 100 - 115d112 < chr1 27003383 27003453 401078 100 + 308d304 < chr1 67919095 67919174 458371 100 - 317d312 < chr1 70182988 70182994 240451 100 + 336d330 < chr1 74612375 74612395 359478 100 - 397d390 < chr1 89611230 89611319 24037 100 - 487d479 < chr1 113433734 113433760 492565 100 + 673d664 < chr1 152364876 152364952 62193 100 - 771d761 < chr1 173149673 173149732 337683 100 - 873d862 < chr1 192327148 192327221 486005 100 - 935d923 < chr1 204842892 204842895 252090 100 - 979d966 < chr1 213387147 213387216 139699 100 - 1021d1007 < chr1 219909272 219909353 381028 100 + 1074d1059 < chr1 229916904 229916936 132877 100 - 1077d1061 < chr1 230205808 230205850 341202 100 - 1116d1099 < chr1 238587424 238587441 119251 100 + 1223d1205 < chr2 9180164 9180241 410939 100 + 1227d1208 < chr2 10286862 10286900 102747 100 - 1251d1231 < chr2 14080614 14080632 319225 100 - 1256d1235 < chr2 15444413 15444497 477964 100 + 1563d1541 < chr2 72312696 72312743 30145 100 + 1586d1563 < chr2 75881143 75881218 394852 100 + 1626d1602 < chr2 83013139 83013202 96558 100 + 1648d1623 < chr2 86697801 86697847 61775 100 - 1687d1661 < chr2 92842913 92842944 378270 100 + 1700d1673 < chr2 95462143 95462216 414391 100 + 1864d1836 < chr2 124252688 124252698 279572 100 + 2028d1999 < chr2 161902060 161902088 131109 100 - 2097d2067 < chr2 173934563 173934570 179607 100 - 2231d2200 < chr2 200696770 200696780 115900 100 - 2501d2469 < chr3 6784676 6784709 401830 100 + 2770d2737 < chr3 60020217 60020255 488795 100 + 2805d2771 < chr3 68385106 68385199 410078 100 + 2838d2803 < chr3 76438675 76438730 1197 100 - 2859d2823 < chr3 81799446 81799461 451210 100 + 2876d2839 < chr3 84553552 84553580 54085 100 - 2944d2906 < chr3 96600622 96600700 375083 100 + 2970d2931 < chr3 102117662 102117684 78634 100 - 3001d2961 < chr3 106511612 106511704 153660 100 + 3024d2983 < chr3 109963398 109963426 158565 100 - 3045d3003 < chr3 113425425 113425486 46792 100 - 3077d3034 < chr3 119396237 119396303 433520 100 + 3152d3108 < chr3 136383081 136383158 14666 100 - 3158d3113 < chr3 137594532 137594586 367279 100 + 3239d3193 < chr3 152061330 152061419 311016 100 + 3253d3206 < chr3 154138748 154138796 148286 100 + 3320d3272 < chr3 167119499 167119545 402496 100 - 3322,3323d3273 < chr3 167161157 167161221 395655 100 - < chr3 167161157 167161249 477843 100 - 3530d3479 < chr4 11334133 11334189 103020 100 + 3562d3510 < chr4 16356889 16356909 96779 100 - 3602d3549 < chr4 24529005 24529029 140900 100 + 3642d3588 < chr4 32635235 32635289 348221 100 + 3796d3741 < chr4 61235328 61235385 399642 100 + 3844d3788 < chr4 72828229 72828246 465837 100 - 3854d3797 < chr4 75314546 75314570 57326 100 + 3890d3832 < chr4 83025590 83025614 214487 100 - 3998d3939 < chr4 103036010 103036081 444012 100 - 4015d3955 < chr4 107012376 107012438 170844 100 + 4080d4019 < chr4 119337105 119337135 324132 100 - 4095d4033 < chr4 122032552 122032631 162962 100 + 4111d4048 < chr4 124910895 124910993 464638 100 - 4130d4066 < chr4 128901133 128901192 485184 100 - 4166d4101 < chr4 135717544 135717568 478396 100 + 4272d4206 < chr4 158543503 158543536 54883 100 + 4373d4306 < chr4 177582825 177582856 35056 100 + 4457d4389 < chr4_ctg9_hap1 360117 360208 41967 100 - 4469d4400 < chr5 2068749 2068778 336896 100 + 4699d4629 < chr5 41539258 41539302 27998 100 + 4744d4673 < chr5 50213593 50213662 319937 100 - 4752d4680 < chr5 50913055 50913154 128909 100 - 4770d4697 < chr5 53608312 53608388 201691 100 - 4845d4771 < chr5 71463588 71463680 489009 100 - 4878d4803 < chr5 76750883 76750967 290945 100 + 5133d5057 < chr5 126963455 126963538 153603 100 + 5214d5137 < chr5 142667040 142667090 150025 100 + 5378d5300 < chr5 173739401 173739404 406533 100 - 5406d5327 < chr5 178447766 178447791 418296 100 + 5499d5419 < chr6 17347638 17347726 77266 100 - 5537d5456 < chr6 24368960 24369007 469640 100 + 5554d5472 < chr6 30320056 30320084 24637 100 - 5660d5577 < chr6 51220350 51220367 338253 100 + 5846d5762 < chr6 93748288 93748364 55386 100 + 5874d5789 < chr6 98172189 98172223 107359 100 + 5889d5803 < chr6 101934220 101934269 300896 100 + 5897d5810 < chr6 102924353 102924425 28620 100 - 6020d5932 < chr6 129788739 129788820 379975 100 - 6058d5969 < chr6 136666210 136666257 414961 100 - 6173d6083 < chr6 157162278 157162303 267632 100 + 6234d6143 < chr6 169381961 169382017 499583 100 - 6515d6423 < chr7 19452220 19452225 273627 100 + 6620d6527 < chr7 40817997 40818088 274394 100 + 6752d6658 < chr7 69036530 69036613 422608 100 + 6822d6727 < chr7 82311341 82311378 308857 100 + 6840d6744 < chr7 85146127 85146211 443468 100 + 6845d6748 < chr7 85756501 85756583 331590 100 - 6866d6768 < chr7 89039245 89039266 2976 100 - 7019d6920 < chr7 122027268 122027296 237448 100 + 7031d6931 < chr7 124481229 124481237 138189 100 - 7039d6938 < chr7 125891977 125892009 359066 100 + 7047d6945 < chr7 127399588 127399636 376616 100 - 7053d6950 < chr7 129424094 129424133 210999 100 - 7081d6977 < chr7 135997401 135997496 173295 100 - 7114d7009 < chr7 142109073 142109093 463495 100 + 7148d7042 < chr7 150239925 150239970 455360 100 + 7214d7107 < chr8 6145176 6145178 130935 100 - 7227d7119 < chr8 7429724 7429763 357625 100 + 7232d7123 < chr8 8285447 8285504 418753 100 - 7269d7159 < chr8 15301646 15301676 160821 100 - 7307d7196 < chr8 24290075 24290126 78725 100 + 7404d7292 < chr8 46830639 46830657 392135 100 - 7431d7318 < chr8 54757317 54757319 267958 100 + 7439d7325 < chr8 56513412 56513437 354092 100 - 7442,7443d7327 < chr8 56655920 56655964 261220 100 + < chr8 56655970 56656020 75116 100 - 7456d7339 < chr8 58900355 58900408 316346 100 - 7514,7515d7396 < chr8 69817925 69817992 305378 100 - < chr8 69818002 69818025 280123 100 - 7610d7490 < chr8 88451670 88451713 473326 100 - 7640d7519 < chr8 95073299 95073333 72657 100 - 7843d7721 < chr8 132282856 132282859 244119 100 + 7934d7811 < chr9 6207469 6207567 412652 100 + 8032d7908 < chr9 23314005 23314089 285910 100 - 8076d7951 < chr9 34194442 34194524 251028 100 - 8377d8251 < chr9 85577448 85577489 261241 100 + 8420,8421d8293 < chr9 95332118 95332190 218482 100 - < chr9 95332118 95332207 218482 100 - 8494d8365 < chr9 112025531 112025547 409486 100 + 8576d8446 < chr9 130258746 130258763 420999 100 + 8589d8458 < chr9 132923879 132923905 77046 100 + 8753d8621 < chr10 30550810 30550887 173260 100 - 8764d8631 < chr10 33331967 33331991 347048 100 + 8768d8634 < chr10 34599233 34599300 158080 100 - 8777d8642 < chr10 36448007 36448061 72216 100 - 8807d8671 < chr10 42218909 42218984 5760 100 + 8835d8698 < chr10 47992664 47992726 175617 100 + 8858d8720 < chr10 52643853 52643951 447920 100 + 8988d8849 < chr10 77946209 77946253 187827 100 - 9051d8911 < chr10 91999424 91999449 81583 100 - 9190d9049 < chr10 119669330 119669420 154994 100 - 9193d9051 < chr10 120622678 120622693 406159 100 - 9234d9091 < chr10 128976070 128976091 99473 100 + 9253d9109 < chr10 133580966 133580982 131318 100 - 9335d9190 < chr11 16163834 16163859 109856 100 + 9400,9401d9254 < chr11 28087410 28087480 468911 100 + < chr11 28087419 28087510 468911 100 + 9404d9256 < chr11 28246081 28246134 180120 100 + 9467d9318 < chr11 39324616 39324711 87999 100 - 9550d9400 < chr11 56685911 56685917 157985 100 + 9557d9406 < chr11 58502651 58502695 277188 100 - 9612d9460 < chr11 70293750 70293771 277399 100 + 9617d9464 < chr11 70880727 70880777 314587 100 - 9634d9480 < chr11 73925915 73925995 151643 100 - 9756,9757d9601 < chr11 95879596 95879634 150224 100 - < chr11 95879599 95879634 150224 100 - 9779d9622 < chr11 99607528 99607620 326167 100 - 9795d9637 < chr11 101989636 101989682 453307 100 + 10039d9880 < chr12 10890856 10890911 19268 100 - 10110d9950 < chr12 22680625 22680693 188754 100 + 10116d9955 < chr12 23725917 23725980 53482 100 + 10222d10060 < chr12 44840987 44841007 406940 100 + 10347d10184 < chr12 67986321 67986325 273240 100 + 10361d10197 < chr12 70639563 70639644 301232 100 - 10397d10232 < chr12 76371230 76371266 153647 100 - 10400d10234 < chr12 76550818 76550871 458863 100 - 10411d10244 < chr12 79770832 79770930 200834 100 + 10466d10298 < chr12 89897697 89897787 103460 100 - 10562d10393 < chr12 107295435 107295459 186771 100 - 10649d10479 < chr12 124219637 124219680 41622 100 - 10661d10490 < chr12 126650945 126651040 216736 100 + 10728d10556 < chr13 7148290 7148317 254533 100 + 10754d10581 < chr13 15564317 15564345 334139 100 - 10765d10591 < chr13 17918504 17918520 222568 100 + 10817d10642 < chr13 28194228 28194236 39828 100 + 10930d10754 < chr13 50737355 50737442 385282 100 - 11025d10848 < chr13 71520518 71520533 249454 100 + 11138d10960 < chr13 93335694 93335771 204671 100 + 11218d11039 < chr13 106935202 106935204 420561 100 - 11256d11076 < chr13 111941988 111941997 410809 100 - 11295d11114 < chr14 3975892 3975984 187214 100 - 11309d11127 < chr14 6723759 6723778 202397 100 + 11403d11220 < chr14 25734164 25734229 182723 100 + 11408d11224 < chr14 26741118 26741212 427498 100 - 11593d11408 < chr14 62178630 62178644 489314 100 + 11688d11502 < chr14 79862847 79862913 377150 100 - 11816d11629 < chr14 105327399 105327413 415159 100 - 12113d11925 < chr15 56332022 56332119 218670 100 + 12161d11972 < chr15 64575689 64575779 138290 100 - 12288d12098 < chr15 93396799 93396804 118142 100 + 12315d12124 < chr15 99645970 99646029 425873 100 + 12321d12129 < chr15 102042469 102042485 441644 100 + 12323d12130 < chr15 102074359 102074434 172723 100 + 12342d12148 < chr16 3031560 3031603 362624 100 - 12406d12211 < chr16 17255129 17255147 265540 100 - 12503d12307 < chr16 36430212 36430219 101793 100 + 12570d12373 < chr16 49067744 49067783 330640 100 - 12610d12412 < chr16 57540371 57540456 194493 100 - 12780d12581 < chr16 88568678 88568737 150289 100 - 12879d12679 < chr17 20285309 20285331 271015 100 + 13084d12883 < chr17 63945099 63945116 295250 100 + 13249d13047 < chr18 11185676 11185751 253385 100 - 13362d13159 < chr18 36615811 36615890 263972 100 - 13391d13187 < chr18 41336890 41336983 23596 100 + 13456d13251 < chr18 55105303 55105344 170077 100 - 13468d13262 < chr18 57258422 57258481 305487 100 - 13501d13294 < chr18 62837873 62837907 350866 100 - 13792d13584 < chr19 39779932 39779946 368977 100 + 13805d13596 < chr19 42556845 42556880 199008 100 + 13954d13744 < chr20 14855905 14855939 296707 100 + 14001d13790 < chr20 25218402 25218477 190427 100 + 14054d13842 < chr20 34299632 34299655 223170 100 - 14077d13864 < chr20 38297508 38297588 103546 100 + 14139d13925 < chr20 50092492 50092502 64930 100 + 14142d13927 < chr20 50786075 50786108 80270 100 + 14146d13930 < chr20 51415794 51415847 462735 100 - 14176d13959 < chr20 55249968 55250020 371564 100 - 14196d13978 < chr20 58538739 58538833 332879 100 + 14215d13996 < chr20 62164503 62164520 161753 100 + 14227d14007 < chr21 2609226 2609303 492422 100 - 14347d14126 < chr21 27854023 27854080 451269 100 + 14355,14356d14133 < chr21 28754174 28754221 30364 100 - < chr21 28754174 28754233 30364 100 - 14598d14374 < chr22 29975574 29975605 318174 100 + 14626d14401 < chr22 36351004 36351031 459740 100 + 14669d14443 < chr22 43332474 43332509 185002 100 + 14721d14494 < chrUn_gl000220 38833 38913 356441 100 - 14730a14504 > chrUn_gl000230 41060 41071 104139 100 + 14786d14559 < chrX 9671470 9671520 136934 100 + 14796d14568 < chrX 12047866 12047908 301444 100 + 14814d14585 < chrX 16229774 16229848 152275 100 + 14873d14643 < chrX 25922160 25922206 425361 100 - 14898d14667 < chrX 32504688 32504779 424337 100 - 14900d14668 < chrX 32541182 32541242 107133 100 + 15071d14838 < chrX 62081980 62082020 64256 100 - 15074d14840 < chrX 62373549 62373592 485865 100 - 15154d14919 < chrX 78460634 78460706 153950 100 + 15206d14970 < chrX 90572923 90573021 338394 100 - 15308d15071 < chrX 108837622 108837644 287787 100 - 15366d15128 < chrX 122515404 122515411 308622 100 - 15444d15205 < chrX 139834063 139834157 53935 100 - 15485d15245 < chrX 147063435 147063499 442281 100 - 15515d15274 < chrX 152383936 152384007 261288 100 + 15528d15286 < chrX 154142139 154142186 465939 100 - 15612d15369 < chrY 20597089 20597160 104172 100 - 15691d15447 < chrY 35189314 35189340 160423 100 + 15705d15460 < chrY 37335865 37335932 346919 100 - 15779d15533 < chrY 51768018 51768079 110067 100 + chr1 10 20 chr1 80 100 chr2 50 80 chr2 100 120 chr10 5 50 chr10 80 120 chr11 20 60 chr11 80 120 chr12 10 50 chr12 60 90 chr1_gl0003 20 80 set -e; echo -e \ "\n########################################################### # # CHROMOSOME SORT ORDER AND NAMING CONVENTIONS # ###########################################################\n" BT=${BT-../../../bin/bedtools} FAILURES=0; check() { if diff $1 $2; then echo ok else FAILURES=$(expr $FAILURES + 1); echo fail fi } ########################################################### # Test query against DB with reverse order ############################################################ echo -e " intersect.t01...\c" echo \ "ERROR: chromomsome sort ordering for file sq1.bed is inconsistent with other files. Record was: chr12 10 20" > exp $BT intersect -a sq1.bed -b sdb1.bed -sorted 2>&1 > /dev/null | cat - > obs check obs exp rm obs ########################################################### # Test query with 2dbs, one of which is out of order ############################################################ echo -e " intersect.t02...\c" echo \ "ERROR: Sort order was unspecified, and file q1a_num.bed is not sorted lexicographically. Please rerun with the -g option for a genome file. See documentation for details." > exp $BT intersect -a q1a_num.bed -b db1_num.bed db2_numBackwards.bed -sorted 2>&1 > /dev/null | cat - > obs check obs exp rm obs ########################################################### # Test query with 3dbs, one of which is out of order ############################################################ echo -e " intersect.t03...\c" echo \ "ERROR: Sort order was unspecified, and file db3_numBackwards.bed is not sorted lexicographically. Please rerun with the -g option for a genome file. See documentation for details." > exp $BT intersect -a q1a_num.bed -b db1_num.bed db2_num.bed db3_numBackwards.bed -sorted 2>&1 > /dev/null | cat - > obs check obs exp rm obs ########################################################### # Test query with 2 dbs, one of which has a chrom # that the query does not ############################################################ echo -e " intersect.t04...\c" echo \ "ERROR: Database file db1_num.bed contains chromosome chr3, but the query file does not. Please rerun with the -g option for a genome file. See documentation for details." >exp $BT intersect -a q1_num.bed -b db1_num.bed db2_num.bed -sorted 2>&1 > /dev/null | cat - > obs check obs exp rm obs ########################################################### # Test query with db that is missing "chr" in one of it's # chroms. ############################################################ echo -e " intersect.t05...\c" echo \ "***** WARNING: File db1_noChr.bed has inconsistent naming convention for record: 2 50 80" > exp $BT intersect -a q1_num.bed -b db1_noChr.bed -sorted 2>&1 > /dev/null | cat - | head -2 > obs check obs exp rm obs ########################################################### # Test query with db that has leading zero in it's chrom # names. ############################################################ echo -e " intersect.t06...\c" echo \ "***** WARNING: File db1_leadingZero.txt has a record where naming convention (leading zero) is inconsistent with other files: chr01 10 20" > exp $BT intersect -a q1_num.bed -b db1_leadingZero.txt -sorted 2>&1 > /dev/null | cat - | head -2 > obs check obs exp rm obs ########################################################### # Test that leading zeroes are allowed if they appear after # an underscore ############################################################ echo -e " intersect.t07...\c" echo \ "chr1 10 20 chr1 80 100 chr2 50 80 chr2 100 120 chr10 5 50 chr10 80 120 chr11 20 60 chr11 80 120 chr12 10 50 chr12 60 90 chr1_gl0003 20 80" > exp $BT intersect -a q1_gls.bed -b q1_gls.bed -sorted > obs check exp obs rm exp obs ########################################################### # Test lexico, all chroms vs all chroms ############################################################ echo -e " intersect.t08...\c" echo \ "chr1 10 20 chr10 10 20 chr11 10 20 chr12 10 20 chr2 10 20" > exp $BT intersect -a alpha_all.bed -b alpha_all.bed -sorted > obs check exp obs rm exp obs ########################################################### # Test lexico, all chroms vs missing chroms ############################################################ echo -e " intersect.t09...\c" echo \ "chr1 10 20 chr11 10 20" > exp $BT intersect -a alpha_all.bed -b alpha_missing.bed -sorted > obs check exp obs rm exp obs ########################################################### # Test all lexico vs all numeric chroms ############################################################ echo -e " intersect.t10...\c" echo \ "ERROR: chromomsome sort ordering for file num_all.bed is inconsistent with other files. Record was: chr10 10 20" > exp $BT intersect -a alpha_all.bed -b num_all.bed -sorted 2>&1 > /dev/null | cat - > obs check exp obs rm exp obs ########################################################### # Test all lexico vs missing numeric chroms ############################################################ echo -e " intersect.t11...\c" echo \ "ERROR: Database file num_missing.bed contains chromosome chr3, but the query file does not. Please rerun with the -g option for a genome file. See documentation for details." > exp $BT intersect -a alpha_all.bed -b num_missing.bed -sorted 2>&1 > /dev/null | cat - > obs check exp obs rm exp obs ########################################################### # Test lexico missing vs all lexico chroms ############################################################ echo -e " intersect.t12...\c" echo \ "chr1 10 20 chr11 10 20" > exp $BT intersect -a alpha_missing.bed -b alpha_all.bed -sorted > obs check exp obs rm exp obs ########################################################### # Test lexico missing vs lexico missing chroms ############################################################ echo -e " intersect.t13...\c" echo \ "chr1 10 20 chr11 10 20 chr3 10 20" > exp $BT intersect -a alpha_missing.bed -b alpha_missing.bed -sorted > obs check exp obs rm exp obs ########################################################### # Test lexico missing vs numeric all chroms ############################################################ echo -e " intersect.t14...\c" echo \ "ERROR: Sort order was unspecified, and file num_all.bed is not sorted lexicographically. Please rerun with the -g option for a genome file. See documentation for details." > exp $BT intersect -a alpha_missing.bed -b num_all.bed -sorted 2>&1 > /dev/null | cat - > obs check exp obs rm exp obs ########################################################### # Test lexico missing vs num missing ############################################################ echo -e " intersect.t15...\c" echo \ "ERROR: chromomsome sort ordering for file num_missing.bed is inconsistent with other files. Record was: chr11 10 20" > exp $BT intersect -a alpha_missing.bed -b num_missing.bed -sorted 2>&1 > /dev/null | cat - > obs check exp obs rm exp obs ########################################################### # Test numeric all vs lexico all ############################################################ echo -e " intersect.t16...\c" echo \ "ERROR: chromomsome sort ordering for file num_all.bed is inconsistent with other files. Record was: chr10 10 20" > exp $BT intersect -a num_all.bed -b alpha_all.bed -sorted 2>&1 > /dev/null | cat - > obs check exp obs rm exp obs ########################################################### # Test numeric all vs lexico missing ############################################################ echo -e " intersect.t17...\c" echo \ "ERROR: Sort order was unspecified, and file num_all.bed is not sorted lexicographically. Please rerun with the -g option for a genome file. See documentation for details." > exp $BT intersect -a num_all.bed -b alpha_missing.bed -sorted 2>&1 > /dev/null | cat - > obs check exp obs rm exp obs ########################################################### # Test numeric all vs numeric all ############################################################ echo -e " intersect.t18...\c" echo \ "chr1 10 20 chr2 10 20 chr10 10 20 chr11 10 20 chr12 10 20" > exp $BT intersect -a num_all.bed -b num_all.bed -sorted > obs check exp obs ########################################################### # Test numeric all vs numeric missing ############################################################ echo -e " intersect.t19...\c" echo \ "ERROR: Database file num_missing.bed contains chromosome chr3, but the query file does not. Please rerun with the -g option for a genome file. See documentation for details." > exp $BT intersect -a num_all.bed -b num_missing.bed -sorted 2>&1 > /dev/null | cat - > obs check exp obs rm exp obs ########################################################### # Test numeric missing vs lexico all ############################################################ echo -e " intersect.20...\c" echo \ "ERROR: Sort order was unspecified, and file num_missing.bed is not sorted lexicographically. Please rerun with the -g option for a genome file. See documentation for details." > exp $BT intersect -a num_missing.bed -b alpha_all.bed -sorted 2>&1 > /dev/null | cat - > obs check exp obs rm exp obs ########################################################### # Test numeric missing vs lexico missing ############################################################ echo -e " intersect.21...\c" echo \ "ERROR: chromomsome sort ordering for file num_missing.bed is inconsistent with other files. Record was: chr11 10 20" > exp $BT intersect -a num_missing.bed -b alpha_missing.bed -sorted 2>&1 > /dev/null | cat - > obs check exp obs rm exp obs ########################################################### # Test numeric missing vs numeric all ############################################################ echo -e " intersect.22...\c" echo \ "ERROR: Sort order was unspecified, and file num_all.bed is not sorted lexicographically. Please rerun with the -g option for a genome file. See documentation for details." > exp $BT intersect -a num_missing.bed -b num_all.bed -sorted 2>&1 > /dev/null | cat - > obs check exp obs rm exp obs ########################################################### # Test numeric missing vs numeric missing ############################################################ echo -e " intersect.23...\c" echo \ "chr1 10 20 chr3 10 20 chr11 10 20" > exp $BT intersect -a num_missing.bed -b num_missing.bed -sorted > obs check exp obs rm exp obs [[ $FAILURES -eq 0 ]] || exit 1; chr12 10 50 chr12 60 90 chr1 10 20 chr1 80 100 # Query 3 Header Line. chr1 1 20 q1 100 + chr1 40 45 q2 100 + chr1 70 90 q3 100 + chr1 105 120 q4 100 + chr2 1 20 q5 100 + chr2 40 45 q6 100 + chr2 70 90 q7 100 + chr2 105 120 q8 100 + chr3 1 20 q9 100 + chr3 40 45 q10 100 + chr3 70 90 q11 100 + chr3 105 120 q12 100 + chr1 40 50 chr1 110 125 chr2 40 50 chr2 110 125 chr3 40 50 chr3 110 125 chr1 85 115 chr2 85 115 chr10 85 115 chr1 1 20 chr1 40 45 chr1 70 90 chr1 105 120 chr2 1 20 chr2 40 45 chr2 70 90 chr2 105 120 chr3 1 20 chr3 40 45 chr3 70 90 chr3 105 120 # DB 7 Header line. chr1 5 25 d7_1 100 + chr1 65 75 d7_2 100 - chr1 95 100 d7_3 100 + chr2 5 25 d7_4 100 - chr2 65 75 d7_5 100 . chr2 95 100 d7_6 100 - chr3 5 25 d7_7 100 + chr3 65 75 d7_8 100 - chr3 95 100 d7_9 100 . chr1 40 50 chr1 110 125 chr2 40 50 chr2 110 125 chr10 40 50 chr10 110 125 set -e; echo -e \ "\n########################################################### # # MULTIPLE DATABASE INTERSECTION # ###########################################################\n" BT=${BT-../../../bin/bedtools} FAILURES=0; check() { if diff $1 $2; then echo ok else FAILURES=$(expr $FAILURES + 1); echo fail fi } ########################################################### # Test the intersection of a query with 3 dbs against # the merged and sorted result of 3 # seperate intersections of the query with each db. # # First make sure the 3 seperate intersections are correct. # ############################################################ echo -e " intersect.t01...\c" echo \ "chr1 5 20 chr1 70 75 chr2 5 20 chr2 70 75 chr3 5 20 chr3 70 75" > exp1 $BT intersect -a query.bed -b d1.bed > obs check obs exp1 rm obs echo -e " intersect.t02...\c" echo \ "chr1 40 45 chr1 110 120 chr2 40 45 chr2 110 120 chr3 40 45 chr3 110 120" > exp2 $BT intersect -a query.bed -b d2.bed > obs check obs exp2 rm obs echo -e " intersect.t03...\c" echo \ "chr1 85 90 chr1 105 115 chr2 85 90 chr2 105 115 chr3 85 90 chr3 105 115" > exp3 $BT intersect -a query.bed -b d3.bed > obs check obs exp3 rm obs ########################################################### # Now test that the R-tree (unsorted input) with sorted # output will give the correct result ########################################################### echo -e " intersect.t04...\c" cat exp1 exp2 exp3 | sort -k1,1 -k2,2n > exp $BT intersect -a query.bed -b d1.bed d2.bed d3.bed -sortout > obs check exp obs rm obs exp1 exp2 exp3 ########################################################### # And then test that sorted input with sorted # output will give the correct result ########################################################### echo -e " intersect.t05...\c" $BT intersect -a query.bed -b d1.bed d2.bed d3.bed -sorted -sortout > obs check exp obs rm obs exp ########################################################### # # Now repeat the above with chroms in a non-standard order # ########################################################### echo -e " intersect.t06...\c" echo \ "chr1 5 20 chr1 70 75 chr2 5 20 chr2 70 75 chr10 5 20 chr10 70 75" > exp1 $BT intersect -a query2.bed -b d4.bed > obs check obs exp1 rm obs echo -e " intersect.t07...\c" echo \ "chr1 40 45 chr1 110 120 chr2 40 45 chr2 110 120 chr10 40 45 chr10 110 120" > exp2 $BT intersect -a query2.bed -b d5.bed > obs check obs exp2 rm obs echo -e " intersect.t08...\c" echo \ "chr1 85 90 chr1 105 115 chr2 85 90 chr2 105 115 chr10 85 90 chr10 105 115" > exp3 $BT intersect -a query2.bed -b d6.bed > obs check obs exp3 rm obs ########################################################### # Now test that the R-tree (unsorted input) with sorted # output will give the correct result ########################################################### echo -e " intersect.t09...\c" cat exp1 exp2 exp3 | sort -k1.4,1n -k2,2n > exp $BT intersect -a query2.bed -b d4.bed d5.bed d6.bed -g g.bed -sortout > obs check exp obs rm obs exp1 exp2 exp3 ########################################################### # And then test that sorted input with sorted # output will give the correct result ########################################################### echo -e " intersect.t10...\c" $BT intersect -a query2.bed -b d4.bed d5.bed d6.bed -sorted -g g.bed -sortout > obs check exp obs rm obs exp ########################################################### # # TEST VARIOUS CMD LINE OUTPUT OPTIONS # ########################################################### ########################################################### # Test -c option ########################################################### echo -e " intersect.t11...\c" echo \ "chr1 1 20 1 chr1 40 45 1 chr1 70 90 2 chr1 105 120 2 chr2 1 20 1 chr2 40 45 1 chr2 70 90 2 chr2 105 120 2 chr3 1 20 1 chr3 40 45 1 chr3 70 90 2 chr3 105 120 2" > exp $BT intersect -a query.bed -b d1.bed d2.bed d3.bed -c -sorted -sortout > obs check exp obs rm exp obs ########################################################### # Test -C option ########################################################### echo -e " intersect.t12...\c" echo \ "chr1 1 20 1 1 chr1 1 20 2 0 chr1 1 20 3 0 chr1 40 45 1 0 chr1 40 45 2 1 chr1 40 45 3 0 chr1 70 90 1 1 chr1 70 90 2 0 chr1 70 90 3 1 chr1 105 120 1 0 chr1 105 120 2 1 chr1 105 120 3 1 chr2 1 20 1 1 chr2 1 20 2 0 chr2 1 20 3 0 chr2 40 45 1 0 chr2 40 45 2 1 chr2 40 45 3 0 chr2 70 90 1 1 chr2 70 90 2 0 chr2 70 90 3 1 chr2 105 120 1 0 chr2 105 120 2 1 chr2 105 120 3 1 chr3 1 20 1 1 chr3 1 20 2 0 chr3 1 20 3 0 chr3 40 45 1 0 chr3 40 45 2 1 chr3 40 45 3 0 chr3 70 90 1 1 chr3 70 90 2 0 chr3 70 90 3 1 chr3 105 120 1 0 chr3 105 120 2 1 chr3 105 120 3 1" > exp $BT intersect -a query.bed -b d1.bed d2.bed d3.bed -C > obs check exp obs rm exp obs ########################################################### # Test -C with -filenames option ########################################################### echo -e " intersect.t13...\c" echo \ "chr1 1 20 d1.bed 1 chr1 1 20 d2.bed 0 chr1 1 20 d3.bed 0 chr1 40 45 d1.bed 0 chr1 40 45 d2.bed 1 chr1 40 45 d3.bed 0 chr1 70 90 d1.bed 1 chr1 70 90 d2.bed 0 chr1 70 90 d3.bed 1 chr1 105 120 d1.bed 0 chr1 105 120 d2.bed 1 chr1 105 120 d3.bed 1 chr2 1 20 d1.bed 1 chr2 1 20 d2.bed 0 chr2 1 20 d3.bed 0 chr2 40 45 d1.bed 0 chr2 40 45 d2.bed 1 chr2 40 45 d3.bed 0 chr2 70 90 d1.bed 1 chr2 70 90 d2.bed 0 chr2 70 90 d3.bed 1 chr2 105 120 d1.bed 0 chr2 105 120 d2.bed 1 chr2 105 120 d3.bed 1 chr3 1 20 d1.bed 1 chr3 1 20 d2.bed 0 chr3 1 20 d3.bed 0 chr3 40 45 d1.bed 0 chr3 40 45 d2.bed 1 chr3 40 45 d3.bed 0 chr3 70 90 d1.bed 1 chr3 70 90 d2.bed 0 chr3 70 90 d3.bed 1 chr3 105 120 d1.bed 0 chr3 105 120 d2.bed 1 chr3 105 120 d3.bed 1" > exp $BT intersect -a query.bed -b d1.bed d2.bed d3.bed -C -filenames > obs check exp obs rm exp obs ########################################################### # Test -C with -names option ########################################################### echo -e " intersect.t14...\c" echo \ "chr1 1 20 d1 1 chr1 1 20 d2 0 chr1 1 20 d3 0 chr1 40 45 d1 0 chr1 40 45 d2 1 chr1 40 45 d3 0 chr1 70 90 d1 1 chr1 70 90 d2 0 chr1 70 90 d3 1 chr1 105 120 d1 0 chr1 105 120 d2 1 chr1 105 120 d3 1 chr2 1 20 d1 1 chr2 1 20 d2 0 chr2 1 20 d3 0 chr2 40 45 d1 0 chr2 40 45 d2 1 chr2 40 45 d3 0 chr2 70 90 d1 1 chr2 70 90 d2 0 chr2 70 90 d3 1 chr2 105 120 d1 0 chr2 105 120 d2 1 chr2 105 120 d3 1 chr3 1 20 d1 1 chr3 1 20 d2 0 chr3 1 20 d3 0 chr3 40 45 d1 0 chr3 40 45 d2 1 chr3 40 45 d3 0 chr3 70 90 d1 1 chr3 70 90 d2 0 chr3 70 90 d3 1 chr3 105 120 d1 0 chr3 105 120 d2 1 chr3 105 120 d3 1" > exp $BT intersect -a query.bed -b d1.bed d2.bed d3.bed -C -names d1 d2 d3 > obs check exp obs rm exp obs ########################################################### # Test -C with -names option and -f 0.5 ########################################################### echo -e " intersect.t15...\c" echo \ "chr1 1 20 d1 1 chr1 1 20 d2 0 chr1 1 20 d3 0 chr1 40 45 d1 0 chr1 40 45 d2 1 chr1 40 45 d3 0 chr1 70 90 d1 0 chr1 70 90 d2 0 chr1 70 90 d3 0 chr1 105 120 d1 0 chr1 105 120 d2 1 chr1 105 120 d3 1 chr2 1 20 d1 1 chr2 1 20 d2 0 chr2 1 20 d3 0 chr2 40 45 d1 0 chr2 40 45 d2 1 chr2 40 45 d3 0 chr2 70 90 d1 0 chr2 70 90 d2 0 chr2 70 90 d3 0 chr2 105 120 d1 0 chr2 105 120 d2 1 chr2 105 120 d3 1 chr3 1 20 d1 1 chr3 1 20 d2 0 chr3 1 20 d3 0 chr3 40 45 d1 0 chr3 40 45 d2 1 chr3 40 45 d3 0 chr3 70 90 d1 0 chr3 70 90 d2 0 chr3 70 90 d3 0 chr3 105 120 d1 0 chr3 105 120 d2 1 chr3 105 120 d3 1" > exp $BT intersect -a query.bed -b d1.bed d2.bed d3.bed -C -f 0.5 -names d1 d2 d3 > obs check exp obs rm exp obs ########################################################### # Test -C with -names option and -f 1.0 ########################################################### echo -e " intersect.t16...\c" echo \ "chr1 1 20 d1 0 chr1 1 20 d2 0 chr1 1 20 d3 0 chr1 40 45 d1 0 chr1 40 45 d2 1 chr1 40 45 d3 0 chr1 70 90 d1 0 chr1 70 90 d2 0 chr1 70 90 d3 0 chr1 105 120 d1 0 chr1 105 120 d2 0 chr1 105 120 d3 0 chr2 1 20 d1 0 chr2 1 20 d2 0 chr2 1 20 d3 0 chr2 40 45 d1 0 chr2 40 45 d2 1 chr2 40 45 d3 0 chr2 70 90 d1 0 chr2 70 90 d2 0 chr2 70 90 d3 0 chr2 105 120 d1 0 chr2 105 120 d2 0 chr2 105 120 d3 0 chr3 1 20 d1 0 chr3 1 20 d2 0 chr3 1 20 d3 0 chr3 40 45 d1 0 chr3 40 45 d2 1 chr3 40 45 d3 0 chr3 70 90 d1 0 chr3 70 90 d2 0 chr3 70 90 d3 0 chr3 105 120 d1 0 chr3 105 120 d2 0 chr3 105 120 d3 0" > exp $BT intersect -a query.bed -b d1.bed d2.bed d3.bed -C -f 1.0 -names d1 d2 d3 > obs check exp obs rm exp obs ########################################################### # Test -f option ########################################################### echo -e " intersect.t17...\c" echo \ "chr1 5 20 chr1 40 45 chr1 110 120 chr1 105 115 chr2 5 20 chr2 40 45 chr2 110 120 chr2 105 115 chr3 5 20 chr3 40 45 chr3 110 120 chr3 105 115" > exp $BT intersect -a query.bed -b d1.bed d2.bed d3.bed -f .6 > obs check exp obs ########################################################### # Test -s option ########################################################### echo -e " intersect.t18...\c" echo \ "chr1 5 20 q1 100 + chr1 85 90 q3 100 + chr1 110 120 q4 100 + chr1 105 115 q4 100 + chr3 5 20 q9 100 + chr3 85 90 q11 100 + chr3 110 120 q12 100 + chr3 105 115 q12 100 +" > exp $BT intersect -a query3.bed -b d7.bed d8.bed d9.bed -s > obs check exp obs rm exp obs ########################################################### # Test -s option ########################################################### echo -e " intersect.t13...\c" echo \ "chr1 40 45 q2 100 + chr1 70 75 q3 100 + chr2 5 20 q5 100 + chr2 40 45 q6 100 + chr2 85 90 q7 100 + chr2 105 115 q8 100 + chr3 40 45 q10 100 + chr3 70 75 q11 100 +" > exp $BT intersect -a query3.bed -b d7.bed d8.bed d9.bed -S > obs check exp obs rm exp obs ########################################################### # Test -wo option ########################################################### echo -e " intersect.t19...\c" echo \ "chr1 1 20 1 chr1 5 25 15 chr1 40 45 2 chr1 40 50 5 chr1 70 90 1 chr1 65 75 5 chr1 70 90 3 chr1 85 115 5 chr1 105 120 2 chr1 110 125 10 chr1 105 120 3 chr1 85 115 10 chr2 1 20 1 chr2 5 25 15 chr2 40 45 2 chr2 40 50 5 chr2 70 90 1 chr2 65 75 5 chr2 70 90 3 chr2 85 115 5 chr2 105 120 2 chr2 110 125 10 chr2 105 120 3 chr2 85 115 10 chr3 1 20 1 chr3 5 25 15 chr3 40 45 2 chr3 40 50 5 chr3 70 90 1 chr3 65 75 5 chr3 70 90 3 chr3 85 115 5 chr3 105 120 2 chr3 110 125 10 chr3 105 120 3 chr3 85 115 10" > exp $BT intersect -a query.bed -b d1.bed d2.bed d3.bed -wo > obs check exp obs rm exp obs ########################################################### # Test -wa -wb -header option ########################################################### echo -e " intersect.t20...\c" echo \ "# Query 3 Header Line. chr1 1 20 q1 100 + 1 chr1 5 25 d7_1 100 + chr1 40 45 q2 100 + 2 chr1 40 50 d8_1 100 - chr1 70 90 q3 100 + 1 chr1 65 75 d7_2 100 - chr1 70 90 q3 100 + 3 chr1 85 115 d9_1 100 + chr1 105 120 q4 100 + 2 chr1 110 125 d8_2 100 + chr1 105 120 q4 100 + 3 chr1 85 115 d9_1 100 + chr2 1 20 q5 100 + 1 chr2 5 25 d7_4 100 - chr2 40 45 q6 100 + 2 chr2 40 50 d8_3 100 - chr2 70 90 q7 100 + 1 chr2 65 75 d7_5 100 . chr2 70 90 q7 100 + 3 chr2 85 115 d9_1 100 - chr2 105 120 q8 100 + 2 chr2 110 125 d8_4 100 . chr2 105 120 q8 100 + 3 chr2 85 115 d9_1 100 - chr3 1 20 q9 100 + 1 chr3 5 25 d7_7 100 + chr3 40 45 q10 100 + 2 chr3 40 50 d8_5 100 - chr3 70 90 q11 100 + 1 chr3 65 75 d7_8 100 - chr3 70 90 q11 100 + 3 chr3 85 115 d9_1 100 + chr3 105 120 q12 100 + 2 chr3 110 125 d8_6 100 + chr3 105 120 q12 100 + 3 chr3 85 115 d9_1 100 +" > exp $BT intersect -a query3.bed -b d7.bed d8.bed d9.bed -wa -wb -header > obs check exp obs rm exp obs ########################################################### # Test the -filenames option, before db listing ########################################################### echo -e " intersect.t21...\c" echo \ "chr1 1 20 q1 100 + d7.bed chr1 5 25 d7_1 100 + chr1 40 45 q2 100 + d8.bed chr1 40 50 d8_1 100 - chr1 70 90 q3 100 + d7.bed chr1 65 75 d7_2 100 - chr1 70 90 q3 100 + d9.bed chr1 85 115 d9_1 100 + chr1 105 120 q4 100 + d8.bed chr1 110 125 d8_2 100 + chr1 105 120 q4 100 + d9.bed chr1 85 115 d9_1 100 + chr2 1 20 q5 100 + d7.bed chr2 5 25 d7_4 100 - chr2 40 45 q6 100 + d8.bed chr2 40 50 d8_3 100 - chr2 70 90 q7 100 + d7.bed chr2 65 75 d7_5 100 . chr2 70 90 q7 100 + d9.bed chr2 85 115 d9_1 100 - chr2 105 120 q8 100 + d8.bed chr2 110 125 d8_4 100 . chr2 105 120 q8 100 + d9.bed chr2 85 115 d9_1 100 - chr3 1 20 q9 100 + d7.bed chr3 5 25 d7_7 100 + chr3 40 45 q10 100 + d8.bed chr3 40 50 d8_5 100 - chr3 70 90 q11 100 + d7.bed chr3 65 75 d7_8 100 - chr3 70 90 q11 100 + d9.bed chr3 85 115 d9_1 100 + chr3 105 120 q12 100 + d8.bed chr3 110 125 d8_6 100 + chr3 105 120 q12 100 + d9.bed chr3 85 115 d9_1 100 +" > exp $BT intersect -a query3.bed -filenames -b d7.bed d8.bed d9.bed -wa -wb > obs check exp obs rm exp obs ########################################################### # Test the -filenames option, after db listing ########################################################### echo -e " intersect.t22...\c" echo \ "chr1 1 20 q1 100 + d7.bed chr1 5 25 d7_1 100 + chr1 40 45 q2 100 + d8.bed chr1 40 50 d8_1 100 - chr1 70 90 q3 100 + d7.bed chr1 65 75 d7_2 100 - chr1 70 90 q3 100 + d9.bed chr1 85 115 d9_1 100 + chr1 105 120 q4 100 + d8.bed chr1 110 125 d8_2 100 + chr1 105 120 q4 100 + d9.bed chr1 85 115 d9_1 100 + chr2 1 20 q5 100 + d7.bed chr2 5 25 d7_4 100 - chr2 40 45 q6 100 + d8.bed chr2 40 50 d8_3 100 - chr2 70 90 q7 100 + d7.bed chr2 65 75 d7_5 100 . chr2 70 90 q7 100 + d9.bed chr2 85 115 d9_1 100 - chr2 105 120 q8 100 + d8.bed chr2 110 125 d8_4 100 . chr2 105 120 q8 100 + d9.bed chr2 85 115 d9_1 100 - chr3 1 20 q9 100 + d7.bed chr3 5 25 d7_7 100 + chr3 40 45 q10 100 + d8.bed chr3 40 50 d8_5 100 - chr3 70 90 q11 100 + d7.bed chr3 65 75 d7_8 100 - chr3 70 90 q11 100 + d9.bed chr3 85 115 d9_1 100 + chr3 105 120 q12 100 + d8.bed chr3 110 125 d8_6 100 + chr3 105 120 q12 100 + d9.bed chr3 85 115 d9_1 100 +" > exp $BT intersect -a query3.bed -b d7.bed d8.bed d9.bed -filenames -wa -wb > obs check exp obs rm exp obs ########################################################### # Test the -names option, before db listing ########################################################### echo -e " intersect.t23...\c" echo \ "chr1 1 20 q1 100 + blue chr1 5 25 d7_1 100 + chr1 40 45 q2 100 + red chr1 40 50 d8_1 100 - chr1 70 90 q3 100 + blue chr1 65 75 d7_2 100 - chr1 70 90 q3 100 + green chr1 85 115 d9_1 100 + chr1 105 120 q4 100 + red chr1 110 125 d8_2 100 + chr1 105 120 q4 100 + green chr1 85 115 d9_1 100 + chr2 1 20 q5 100 + blue chr2 5 25 d7_4 100 - chr2 40 45 q6 100 + red chr2 40 50 d8_3 100 - chr2 70 90 q7 100 + blue chr2 65 75 d7_5 100 . chr2 70 90 q7 100 + green chr2 85 115 d9_1 100 - chr2 105 120 q8 100 + red chr2 110 125 d8_4 100 . chr2 105 120 q8 100 + green chr2 85 115 d9_1 100 - chr3 1 20 q9 100 + blue chr3 5 25 d7_7 100 + chr3 40 45 q10 100 + red chr3 40 50 d8_5 100 - chr3 70 90 q11 100 + blue chr3 65 75 d7_8 100 - chr3 70 90 q11 100 + green chr3 85 115 d9_1 100 + chr3 105 120 q12 100 + red chr3 110 125 d8_6 100 + chr3 105 120 q12 100 + green chr3 85 115 d9_1 100 +" > exp $BT intersect -a query3.bed -names blue red green -b d7.bed d8.bed d9.bed -wa -wb > obs check exp obs rm exp obs ########################################################### # Test the -names option, after db listing ########################################################### echo -e " intersect.t24...\c" echo \ "chr1 1 20 q1 100 + blue chr1 5 25 d7_1 100 + chr1 40 45 q2 100 + red chr1 40 50 d8_1 100 - chr1 70 90 q3 100 + blue chr1 65 75 d7_2 100 - chr1 70 90 q3 100 + green chr1 85 115 d9_1 100 + chr1 105 120 q4 100 + red chr1 110 125 d8_2 100 + chr1 105 120 q4 100 + green chr1 85 115 d9_1 100 + chr2 1 20 q5 100 + blue chr2 5 25 d7_4 100 - chr2 40 45 q6 100 + red chr2 40 50 d8_3 100 - chr2 70 90 q7 100 + blue chr2 65 75 d7_5 100 . chr2 70 90 q7 100 + green chr2 85 115 d9_1 100 - chr2 105 120 q8 100 + red chr2 110 125 d8_4 100 . chr2 105 120 q8 100 + green chr2 85 115 d9_1 100 - chr3 1 20 q9 100 + blue chr3 5 25 d7_7 100 + chr3 40 45 q10 100 + red chr3 40 50 d8_5 100 - chr3 70 90 q11 100 + blue chr3 65 75 d7_8 100 - chr3 70 90 q11 100 + green chr3 85 115 d9_1 100 + chr3 105 120 q12 100 + red chr3 110 125 d8_6 100 + chr3 105 120 q12 100 + green chr3 85 115 d9_1 100 +" > exp $BT intersect -a query3.bed -b d7.bed d8.bed d9.bed -names blue red green -wa -wb > obs check exp obs rm exp obs [[ $FAILURES -eq 0 ]] || exit 1; # Query 2 Header Line. chr1 1 20 chr1 40 45 chr1 70 90 chr1 105 120 chr2 1 20 chr2 40 45 chr2 70 90 chr2 105 120 chr10 1 20 chr10 40 45 chr10 70 90 chr10 105 120 chr1 85 115 chr2 85 115 chr3 85 115 # DB 8 Header Line. chr1 40 50 d8_1 100 - chr1 110 125 d8_2 100 + chr2 40 50 d8_3 100 - chr2 110 125 d8_4 100 . chr3 40 50 d8_5 100 - chr3 110 125 d8_6 100 + chr1 5 25 chr1 65 75 chr1 95 100 chr2 5 25 chr2 65 75 chr2 95 100 chr3 5 25 chr3 65 75 chr3 95 100 chr1 5 25 chr1 65 75 chr1 95 100 chr2 5 25 chr2 65 75 chr2 95 100 chr10 5 25 chr10 65 75 chr10 95 100 # DB 9 Header Line. chr1 85 115 d9_1 100 + chr2 85 115 d9_1 100 - chr3 85 115 d9_1 100 + chr1 200 chr2 200 chr10 200 chr1 11 20 chr2 11 20 chr10 11 20 r0b```b`fbf"& `(> %`chr1 10000 12000 chr1 15000 20000 chr1 0 10 a1 10 - chr2 10 20 a7 2 + chr3 120 130 a9 4 -chr1 10 20 chr2 10 20 chr2 200 300 chr10 10 20 chr10 20 30#header chr1 0 100 chr1 100 200 chr2 0 100 chr2 100 200 chr3 0 100 chr3 100 200 chr1 0 10 a1 10 + chr1 10 20 a2 5 + chr1 20 30 a3 15 + chr1 120 130 a4 1 + chr3 0 10 a5 1 + chr3 10 20 a6 2 + chr3 20 30 a7 3 + chr3 120 130 a8 4 + chr1 hg19_ccdsGene start_codon 1 9 0.000000 + . gene_id "CCDS30744.1"; transcript_id "CCDS30744.1"; chr1 hg19_ccdsGene CDS 2 11 0.000000 + 0 gene_id "CCDS30744.1"; transcript_id "CCDS30744.1"; chr1 hg19_ccdsGene exon 8 20 0.000000 + . gene_id "CCDS30744.1"; transcript_id "CCDS30744.1"; chr1 hg19_ccdsGene CDS 9 17 0.000000 + 2 gene_id "CCDS30744.1"; transcript_id "CCDS30744.1"; chr1 hg19_ccdsGene exon 40 200 0.000000 + . gene_id "CCDS30744.1"; transcript_id "CCDS30744.1"; chr1 0 50 three_blocks_match 15 + 0 0 0 3 10,10,10, 0,20,40, ##fileformat=VCFv4.1 ##fileDate=20090805 ##source=myImputationProgramV3.1 ##reference=file:///seq/references/1000GenomesPilot-NCBI36.fasta ##contig= ##phasing=partial ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##FILTER= ##FILTER= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT NA00001 NA00002 NA00003 chr1 10 rs6054257 G A 29 PASS NS=3;DP=14;AF=0.5;DB;H2 GT:GQ:DP:HQ 0|0:48:1:51,51 1|0:48:8:51,51 1/1:43:5:.,. chr1 15 . T A 3 q10 NS=3;DP=11;AF=0.017 GT:GQ:DP:HQ 0|0:49:3:58,50 0|1:3:5:65,3 0/0:41:3 chr1 20 rs6040355 A G,T 67 PASS NS=2;DP=10;AF=0.333,0.667;AA=T;DB GT:GQ:DP:HQ 1|2:21:6:23,27 2|1:2:0:18,2 2/2:35:4 chr1 110 . T . 47 PASS NS=3;DP=13;AA=T GT:GQ:DP:HQ 0|0:54:7:56,60 0|0:48:4:51,51 0/0:61:2 chr1 130 microsat1 GTC G,GTCT 50 PASS NS=3;DP=9;AA=G GT:GQ:DP 0/1:35:4 0/2:17:2 1/1:40:3 chr2 110 . T . 47 PASS NS=3;DP=13;AA=T GT:GQ:DP:HQ 0|0:54:7:56,60 0|0:48:4:51,51 0/0:61:2 chr2 130 microsat1 GTC G,GTCT 50 PASS NS=3;DP=9;AA=G GT:GQ:DP 0/1:35:4 0/2:17:2 1/1:40:3 chr1 0 10 a1 10 + chr1 10 20 a2 5 + chr1 11 21 a3 5 + chr1 20 30 a4 15 + chr1 20 30 a5 15 + chr1 20 30 a6 15 + chr1 120 130 a7 1 + chr3 0 10 a8 1 + chr3 10 20 a9 2 + chr3 20 30 a10 3 + chr3 120 130 a11 4 + chr3 120 130 a12 4 + c <- (1,2,3,4,5,-6) a <- c(1,2,3,4,5,-6) std(a) stdev(a) sd(a) quit() chr1 0 10 a1 10 + 1 chr1 10 20 a2 5 + 2 chr1 11 21 a3 5 + 3 chr1 20 30 a4 15 + 4 chr1 20 30 a5 15 + 5 chr1 20 30 a6 15 + -6 chr1 120 130 a7 1 + 7 chr3 0 10 a8 1 + 8 chr3 10 20 a9 2 + 9 chr3 20 30 a10 3 + -10 chr3 120 130 a11 4 + 11 chr3 120 130 a12 4 + 12 set -e; BT=${BT-../../bin/bedtools} FAILURES=0; check() { if diff $1 $2; then echo ok else FAILURES=$(expr $FAILURES + 1); echo fail fi } ########################################################### # Test defaults ############################################################ echo -e " map.t01...\c" echo \ "chr1 0 100 30 chr1 100 200 1 chr2 0 100 . chr2 100 200 . chr3 0 100 6 chr3 100 200 4" > exp $BT map -a ivls.bed -b values.bed > obs check obs exp rm obs exp ########################################################### # Test sum ############################################################ echo -e " map.t02...\c" echo \ "chr1 0 100 30 chr1 100 200 1 chr2 0 100 . chr2 100 200 . chr3 0 100 6 chr3 100 200 4" > exp $BT map -a ivls.bed -b values.bed -o sum > obs check obs exp rm obs exp ########################################################### # Test count ############################################################ echo -e " map.t03...\c" echo \ "chr1 0 100 3 chr1 100 200 1 chr2 0 100 0 chr2 100 200 0 chr3 0 100 3 chr3 100 200 1" > exp $BT map -a ivls.bed -b values.bed -o count > obs check obs exp rm obs exp ########################################################### # Test mean ############################################################ echo -e " map.t04...\c" echo \ "chr1 0 100 10 chr1 100 200 1 chr2 0 100 . chr2 100 200 . chr3 0 100 2 chr3 100 200 4" > exp $BT map -a ivls.bed -b values.bed -o mean > obs check obs exp rm obs exp ########################################################### # Test max ############################################################ echo -e " map.t05...\c" echo \ "chr1 0 100 15 chr1 100 200 1 chr2 0 100 . chr2 100 200 . chr3 0 100 3 chr3 100 200 4" > exp $BT map -a ivls.bed -b values.bed -o max > obs check obs exp rm obs exp ########################################################### # Test min ############################################################ echo -e " map.t06...\c" echo \ "chr1 0 100 5 chr1 100 200 1 chr2 0 100 . chr2 100 200 . chr3 0 100 1 chr3 100 200 4" > exp $BT map -a ivls.bed -b values.bed -o min > obs check obs exp rm obs exp ########################################################### # Test mode ############################################################ echo -e " map.t07...\c" echo \ "chr1 0 100 5 chr1 100 200 1 chr2 0 100 . chr2 100 200 . chr3 0 100 1 chr3 100 200 4" > exp $BT map -a ivls.bed -b values2.bed -o mode > obs check obs exp rm obs exp ########################################################### # Test anti-mode ############################################################ echo -e " map.t08...\c" echo \ "chr1 0 100 10 chr1 100 200 1 chr2 0 100 . chr2 100 200 . chr3 0 100 1 chr3 100 200 4" > exp $BT map -a ivls.bed -b values2.bed -o antimode > obs check obs exp rm obs exp ########################################################### # Test column extraction from BEDPLUS ############################################################ echo -e " map.t09...\c" echo \ "chr1 0 100 1,2,3,4,5,-6 chr1 100 200 7 chr2 0 100 . chr2 100 200 . chr3 0 100 8,9,-10 chr3 100 200 11,12" > exp $BT map -a ivls.bed -b values4.bed -c 7 -o collapse > obs check obs exp rm obs exp ########################################################### # Test min ############################################################ echo -e " map.t10...\c" echo \ "chr1 0 100 -6 chr1 100 200 7 chr2 0 100 . chr2 100 200 . chr3 0 100 -10 chr3 100 200 11" > exp $BT map -a ivls.bed -b values4.bed -c 7 -o min > obs check obs exp rm obs exp ########################################################### # Test absmin ############################################################ echo -e " map.t11...\c" echo \ "chr1 0 100 1 chr1 100 200 7 chr2 0 100 . chr2 100 200 . chr3 0 100 8 chr3 100 200 11" > exp $BT map -a ivls.bed -b values4.bed -c 7 -o absmin > obs check obs exp rm obs exp ########################################################### # Test max ############################################################ echo -e " map.t12...\c" echo \ "chr1 0 100 5 chr1 100 200 7 chr2 0 100 . chr2 100 200 . chr3 0 100 9 chr3 100 200 12" > exp $BT map -a ivls.bed -b values4.bed -c 7 -o max > obs check obs exp rm obs exp ########################################################### # Test absmax ############################################################ echo -e " map.t13...\c" echo \ "chr1 0 100 6 chr1 100 200 7 chr2 0 100 . chr2 100 200 . chr3 0 100 10 chr3 100 200 12" > exp $BT map -a ivls.bed -b values4.bed -c 7 -o absmax > obs check obs exp rm obs exp ########################################################### # Test GFF column extraction ############################################################ echo -e " map.t14...\c" echo \ "chr1 0 100 chr1,chr1,chr1,chr1,chr1 chr1 100 200 chr1 chr2 0 100 . chr2 100 200 . chr3 0 100 . chr3 100 200 ." > exp $BT map -a ivls.bed -b test.gff -c 1 -o collapse > obs check obs exp rm obs exp ########################################################### # Test GFF column extraction ############################################################ echo -e " map.t15...\c" echo \ "chr1 0 100 hg19_ccdsGene,hg19_ccdsGene,hg19_ccdsGene,hg19_ccdsGene,hg19_ccdsGene chr1 100 200 hg19_ccdsGene chr2 0 100 . chr2 100 200 . chr3 0 100 . chr3 100 200 ." > exp $BT map -a ivls.bed -b test.gff -c 2 -o collapse > obs check obs exp rm obs exp ########################################################### # Test GFF column extraction ############################################################ echo -e " map.t16...\c" echo \ "chr1 0 100 start_codon,CDS,exon,CDS,exon chr1 100 200 exon chr2 0 100 . chr2 100 200 . chr3 0 100 . chr3 100 200 ." > exp $BT map -a ivls.bed -b test.gff -c 3 -o collapse > obs check obs exp rm obs exp ########################################################### # Test GFF column extraction ############################################################ echo -e " map.t17...\c" echo \ "chr1 0 100 1,2,8,9,40 chr1 100 200 40 chr2 0 100 . chr2 100 200 . chr3 0 100 . chr3 100 200 ." > exp $BT map -a ivls.bed -b test.gff -c 4 -o collapse > obs check obs exp rm obs exp ########################################################### # Test GFF column extraction ############################################################ echo -e " map.t18...\c" echo \ "chr1 0 100 9,11,20,17,200 chr1 100 200 200 chr2 0 100 . chr2 100 200 . chr3 0 100 . chr3 100 200 ." > exp $BT map -a ivls.bed -b test.gff -c 5 -o collapse > obs check obs exp rm obs exp ########################################################### # Test GFF column extraction ############################################################ echo -e " map.t19...\c" echo \ "chr1 0 100 0.000000,0.000000,0.000000,0.000000,0.000000 chr1 100 200 0.000000 chr2 0 100 . chr2 100 200 . chr3 0 100 . chr3 100 200 ." > exp $BT map -a ivls.bed -b test.gff -c 6 -o collapse > obs check obs exp rm obs exp ########################################################### # Test GFF column extraction ############################################################ echo -e " map.t20...\c" echo \ "chr1 0 100 +,+,+,+,+ chr1 100 200 + chr2 0 100 . chr2 100 200 . chr3 0 100 . chr3 100 200 ." > exp $BT map -a ivls.bed -b test.gff -c 7 -o collapse > obs check obs exp rm obs exp ########################################################### # Test GFF column extraction ############################################################ echo -e " map.t21...\c" echo \ "chr1 0 100 .,0,.,2,. chr1 100 200 . chr2 0 100 . chr2 100 200 . chr3 0 100 . chr3 100 200 ." > exp $BT map -a ivls.bed -b test.gff -c 8 -o collapse > obs check obs exp rm obs exp ########################################################### # Test GFF column extraction ############################################################ echo -e " map.t22..\c" echo \ "chr1 0 100 gene_id \"CCDS30744.1\"; transcript_id \"CCDS30744.1\";,gene_id \"CCDS30744.1\"; transcript_id \"CCDS30744.1\";,gene_id \"CCDS30744.1\"; transcript_id \"CCDS30744.1\";,gene_id \"CCDS30744.1\"; transcript_id \"CCDS30744.1\";,gene_id \"CCDS30744.1\"; transcript_id \"CCDS30744.1\"; chr1 100 200 gene_id \"CCDS30744.1\"; transcript_id \"CCDS30744.1\"; chr2 0 100 . chr2 100 200 . chr3 0 100 . chr3 100 200 ." > exp $BT map -a ivls.bed -b test.gff -c 9 -o collapse > obs check obs exp rm obs exp ########################################################### # Test VCF column extraction ############################################################ echo -e " map.t23..\c" echo \ "chr1 0 100 chr1,chr1,chr1 chr1 100 200 chr1,chr1 chr2 0 100 . chr2 100 200 chr2,chr2 chr3 0 100 . chr3 100 200 ." > exp $BT map -a ivls.bed -b test.vcf -c 1 -o collapse > obs check obs exp rm obs exp ########################################################### # Test VCF column extraction ############################################################ echo -e " map.t24..\c" echo \ "chr1 0 100 10,15,20 chr1 100 200 110,130 chr2 0 100 . chr2 100 200 110,130 chr3 0 100 . chr3 100 200 ." > exp $BT map -a ivls.bed -b test.vcf -c 2 -o collapse > obs check obs exp rm obs exp ########################################################### # Test VCF column extraction ############################################################ echo -e " map.t25..\c" echo \ "chr1 0 100 rs6054257,.,rs6040355 chr1 100 200 .,microsat1 chr2 0 100 . chr2 100 200 .,microsat1 chr3 0 100 . chr3 100 200 ." > exp $BT map -a ivls.bed -b test.vcf -c 3 -o collapse > obs check obs exp rm obs exp ########################################################### # Test VCF column extraction ############################################################ echo -e " map.t26..\c" echo \ "chr1 0 100 G,T,A chr1 100 200 T,GTC chr2 0 100 . chr2 100 200 T,GTC chr3 0 100 . chr3 100 200 ." > exp $BT map -a ivls.bed -b test.vcf -c 4 -o collapse > obs check obs exp rm obs exp ########################################################### # Test VCF column extraction ############################################################ echo -e " map.t27..\c" echo \ "chr1 0 100 A,A,G,T chr1 100 200 .,G,GTCT chr2 0 100 . chr2 100 200 .,G,GTCT chr3 0 100 . chr3 100 200 ." > exp $BT map -a ivls.bed -b test.vcf -c 5 -o collapse > obs check obs exp rm obs exp ########################################################### # Test VCF column extraction ############################################################ echo -e " map.t28..\c" echo \ "chr1 0 100 29,3,67 chr1 100 200 47,50 chr2 0 100 . chr2 100 200 47,50 chr3 0 100 . chr3 100 200 ." > exp $BT map -a ivls.bed -b test.vcf -c 6 -o collapse > obs check obs exp rm obs exp ########################################################### # Test VCF column extraction ############################################################ echo -e " map.t29..\c" echo \ "chr1 0 100 PASS,q10,PASS chr1 100 200 PASS,PASS chr2 0 100 . chr2 100 200 PASS,PASS chr3 0 100 . chr3 100 200 ." > exp $BT map -a ivls.bed -b test.vcf -c 7 -o collapse > obs check obs exp rm obs exp ########################################################### # Test VCF column extraction ############################################################ echo -e " map.t30..\c" echo \ "chr1 0 100 NS=3;DP=14;AF=0.5;DB;H2,NS=3;DP=11;AF=0.017,NS=2;DP=10;AF=0.333,0.667;AA=T;DB chr1 100 200 NS=3;DP=13;AA=T,NS=3;DP=9;AA=G chr2 0 100 . chr2 100 200 NS=3;DP=13;AA=T,NS=3;DP=9;AA=G chr3 0 100 . chr3 100 200 ." > exp $BT map -a ivls.bed -b test.vcf -c 8 -o collapse > obs check obs exp rm obs exp ########################################################### # Test VCF column extraction ############################################################ echo -e " map.t31..\c" echo \ "chr1 0 100 GT:GQ:DP:HQ,GT:GQ:DP:HQ,GT:GQ:DP:HQ chr1 100 200 GT:GQ:DP:HQ,GT:GQ:DP chr2 0 100 . chr2 100 200 GT:GQ:DP:HQ,GT:GQ:DP chr3 0 100 . chr3 100 200 ." > exp $BT map -a ivls.bed -b test.vcf -c 9 -o collapse > obs check obs exp rm obs exp ########################################################### # Test VCF column extraction ############################################################ echo -e " map.t32..\c" echo \ "chr1 0 100 0|0:48:1:51,51,0|0:49:3:58,50,1|2:21:6:23,27 chr1 100 200 0|0:54:7:56,60,0/1:35:4 chr2 0 100 . chr2 100 200 0|0:54:7:56,60,0/1:35:4 chr3 0 100 . chr3 100 200 ." > exp $BT map -a ivls.bed -b test.vcf -c 10 -o collapse > obs check obs exp rm obs exp ########################################################### # Test VCF column extraction ############################################################ echo -e " map.t33..\c" echo \ " ***** ***** ERROR: Requested column 15, but database file test.vcf only has fields 1 - 12." > exp $BT map -a ivls.bed -b test.vcf -c 15 -o collapse 2>&1 > /dev/null | head -3> obs check obs exp rm obs exp ########################################################### # Test -header ############################################################ echo -e " map.t33..\c" echo \ "#header chr1 0 100 0|0:48:1:51,51,0|0:49:3:58,50,1|2:21:6:23,27 chr1 100 200 0|0:54:7:56,60,0/1:35:4 chr2 0 100 . chr2 100 200 0|0:54:7:56,60,0/1:35:4 chr3 0 100 . chr3 100 200 ." > exp $BT map -a ivls.bed -b test.vcf -header -c 10 -o collapse > obs check obs exp rm obs exp ########################################################### # Test -null ############################################################ echo -e " map.t33..\c" echo \ "chr1 0 100 0|0:48:1:51,51,0|0:49:3:58,50,1|2:21:6:23,27 chr1 100 200 0|0:54:7:56,60,0/1:35:4 chr2 0 100 NULL chr2 100 200 0|0:54:7:56,60,0/1:35:4 chr3 0 100 NULL chr3 100 200 NULL" > exp $BT map -a ivls.bed -b test.vcf -null NULL -c 10 -o collapse > obs check obs exp ########################################################### # Test -s ############################################################ echo -e " map.t34..\c" echo \ "chr1 0 10 a1 10 - . chr2 10 20 a7 2 + . chr3 120 130 a9 4 - ." > exp $BT map -a ivls2.bed -b values.bed -c 4 -o collapse -s > obs check obs exp ########################################################### # Test -S ############################################################ echo -e " map.t35..\c" echo \ "chr1 0 10 a1 10 - a1 chr2 10 20 a7 2 + . chr3 120 130 a9 4 - a8" > exp $BT map -a ivls2.bed -b values.bed -c 4 -o collapse -S > obs check obs exp ########################################################### # Test -f 0.1 ############################################################ echo -e " map.t36..\c" echo \ "chr1 0 10 a1 10 - a1 chr2 10 20 a7 2 + . chr3 120 130 a9 4 - a8" > exp $BT map -a ivls2.bed -b values5.bed -c 4 -o collapse -f 0.1 > obs check obs exp ########################################################### # Test -f 0.7 ############################################################ echo -e " map.t37..\c" echo \ "chr1 0 10 a1 10 - . chr2 10 20 a7 2 + . chr3 120 130 a9 4 - a8" > exp $BT map -a ivls2.bed -b values5.bed -c 4 -o collapse -f 0.7 > obs check obs exp ########################################################### # Test -f 0.9 ############################################################ echo -e " map.t38..\c" echo \ "chr1 0 10 a1 10 - . chr2 10 20 a7 2 + . chr3 120 130 a9 4 - ." > exp $BT map -a ivls2.bed -b values5.bed -c 4 -o collapse -f 0.9 > obs check obs exp ########################################################### # Test -g ############################################################ echo -e " map.t39..\c" echo \ "chr1 10 20 chr1 chr2 10 20 chr2 chr2 200 300 . chr10 10 20 chr10 chr10 20 30 ." > exp $BT map -a a.vsorted.bed -b b.vsorted.bed -c 1 -o collapse > obs check obs exp ########################################################### # Test -g ############################################################ echo -e " map.t40..\c" echo \ "chr1 10 20 chr1 chr2 10 20 chr2 chr2 200 300 . chr10 10 20 chr10 chr10 20 30 ." > exp $BT map -g genome -a a.vsorted.bed -b b.vsorted.bed -c 1 -o collapse > obs check obs exp ########################################################### # Test invalid column ############################################################ echo -e " map.t41..\c" echo \ " ***** ***** ERROR: Requested column 41, but database file test.vcf only has fields 1 - 12." > exp $BT map -a ivls.bed -b test.vcf -c 41 -o collapse 2>&1 > /dev/null | head -3> obs check obs exp rm obs exp ########################################################### # Test invalid column ############################################################ echo -e " map.t42..\c" echo \ " ***** ***** ERROR: Requested column -1, but database file test.vcf only has fields 1 - 12." > exp $BT map -a ivls.bed -b test.vcf -c -1 -o collapse 2>&1 > /dev/null | head -3> obs check obs exp rm obs exp ########################################################### # Test invalid column ############################################################ echo -e " map.t43..\c" echo \ " ***** ***** ERROR: Requested column 0, but database file test.vcf only has fields 1 - 12." > exp $BT map -a ivls.bed -b test.vcf -c 0 -o collapse 2>&1 > /dev/null | head -3> obs check obs exp rm obs exp ########################################################### # # DEPRECATED # Test that Bam database is not allowed ############################################################ echo -e " map.t44...\c" #echo -e "\n*****\n***** ERROR: BAM database file not currently supported for column operations." > exp #$BT map -a ivls.bed -b values.bam 2> obs #check obs exp #rm obs exp echo ok ########################################################### # Test that -split option works correctly ############################################################ echo -e " map.t45...\c" echo "chr1 0 50 three_blocks_match 15 + 0 0 0 3 10,10,10, 0,20,40, ." > exp $BT map -o sum -a three_blocks_match.bed -b three_blocks_nomatch.bed -split > obs check obs exp rm obs exp ########################################################### # # # Tests for multiple columns and operations # # ############################################################ ########################################################### # Test that error is given when ops outnumber columns ############################################################ echo -e " map.t46...\c" echo \ "chr1 0 100 3 30 chr1 100 200 1 1 chr2 0 100 0 . chr2 100 200 0 . chr3 0 100 3 6 chr3 100 200 1 4" > exp $BT map -a ivls.bed -b values.bed -o count,sum > obs check obs exp rm obs exp ########################################################### # Test that error is given when columns outnumber ops, # if there are two or more ops. ############################################################ echo -e " map.t47...\c" echo \ " ***** ***** ERROR: There are 3 columns given, but there are 2 operations." > exp $BT map -a ivls.bed -b values.bed -c 5,1,2 -o count,sum 2>&1 > /dev/null | head -3 > obs check obs exp rm obs exp ########################################################### # Test that numeric ops for non-numeric columns are # allowed, but give a warning ############################################################ echo -e " map.t48...\c" echo \ " ***** WARNING: Non numeric value chr1 in 1. ***** WARNING: Non numeric value chr1 in 1. ***** WARNING: Non numeric value chr3 in 1. ***** WARNING: Non numeric value chr3 in 1." > exp $BT map -a ivls.bed -b values.bed -c 1 -o sum 2>&1 > /dev/null | cat - > obs check obs exp rm obs exp ########################################################### # Test that multiple columns are allowed with a # single operation ############################################################ echo -e " map.t49...\c" echo \ "chr1 0 100 65 9 chr1 100 200 1 7 chr2 0 100 . . chr2 100 200 . . chr3 0 100 6 7 chr3 100 200 8 23" > exp $BT map -a ivls.bed -b values4.bed -c 5,7 -o sum > obs check obs exp rm obs exp ########################################################### # Test that multiple columns are allowed with an # equal number of ops that aren't all the same ############################################################ echo -e " map.t50...\c" echo \ "chr1 0 100 13.5 65 9 chr1 100 200 120 1 7 chr2 0 100 . . . chr2 100 200 . . . chr3 0 100 10 6 7 chr3 100 200 120 8 23" > exp $BT map -a ivls.bed -b values4.bed -c 2,5,7 -o mean,sum,sum > obs check obs exp rm obs exp ########################################################### # Test stdev ############################################################ echo -e " map.t51...\c" echo \ "chr1 0 100 3.593976442 chr1 100 200 0 chr2 0 100 . chr2 100 200 . chr3 0 100 8.730533902 chr3 100 200 0.5" > exp $BT map -a ivls.bed -b values4.bed -c 7 -o stdev > obs check obs exp rm obs exp ########################################################### # Test sstdev ############################################################ echo -e " map.t52...\c" echo \ "chr1 0 100 3.937003937 chr1 100 200 . chr2 0 100 . chr2 100 200 . chr3 0 100 10.69267662 chr3 100 200 0.7071067812" > exp $BT map -a ivls.bed -b values4.bed -c 7 -o sstdev > obs check obs exp rm obs exp ########################################################### # Test BAM file as DB ############################################################ echo -e " map.t53...\c" echo \ "chr1 10000 12000 2.5 chr1 15000 20000 11.44444444" > exp $BT map -a d.bed -b fullFields.bam -c 5 -o mean > obs check exp obs rm exp obs ########################################################### # 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=D08D/WݼK/Upfzfd>S,.oy+lEӔYuu8ibF-fLǦfk֠Wm81Td\'m|Q^cy+7@Chi!~ctV!I$i3 (\[FNJ~0;߉BCchr1 10 20 chr1 4 10 a1 10 + chr1 14 20 a2 5 + chr1 26 30 a3 15 + chr1 127 130 a4 1 + chr3 0 10 a5 1 + chr3 15 20 a6 2 + chr3 22 30 a7 3 + chr3 122 130 a8 4 +set -e; BT=${BT-../../bin/bedtools} FAILURES=0; check() { if diff $1 $2; then echo ok else FAILURES=$(expr $FAILURES + 1); echo fail fi } # cat in.bed #chr1 10 20 1,2,3 10,20,30 #chr1 40 50 4,5,6 40,50,60 ########################################################### # expand one column ########################################################### echo -e " expand.t1...\c" echo \ "chr1 10 20 1 10,20,30 chr1 10 20 2 10,20,30 chr1 10 20 3 10,20,30 chr1 40 50 4 40,50,60 chr1 40 50 5 40,50,60 chr1 40 50 6 40,50,60" > exp $BT expand -i expand.txt -c 4 > obs check obs exp rm obs exp ########################################################### # expand multiple columns ########################################################### echo -e " expand.t2...\c" echo \ "chr1 10 20 1 10 chr1 10 20 2 20 chr1 10 20 3 30 chr1 40 50 4 40 chr1 40 50 5 50 chr1 40 50 6 60" > exp $BT expand -i expand.txt -c 4,5 > obs check obs exp rm obs exp ########################################################### # expand multiple columns while switching order ########################################################### echo -e " expand.t3...\c" echo \ "chr1 10 20 10 1 chr1 10 20 20 2 chr1 10 20 30 3 chr1 40 50 40 4 chr1 40 50 50 5 chr1 40 50 60 6" > exp $BT expand -i expand.txt -c 5,4 > obs check obs exp rm obs exp [[ $FAILURES -eq 0 ]] || exit 1; chr1 10 20 1,2,3 10,20,30 chr1 40 50 4,5,6 40,50,60 chr2L 1 54 . 0.05 chr2L 65 128 . 0.33 chr2L 129 180 . 0.04 chr2L 193 259 . -0.18 chr2L 257 317 . -0.07 chr2L 321 375 . -0.07 chr2L 385 448 . -0.11 chr2L 449 502 . 0.4 chr2L 513 570 . 0.48 chr2L 577 635 . -0.24 chr1 9 30 2 chr1 10 20 1 chr1 11 25 3 chr1 12 30 5 chr1 100 110 4 chr2 11 20 6 chr1 10 20 1 chr1 9 30 2 chr1 11 25 3 chr1 100 110 4 chr1 12 30 5 chr2 11 20 6 chr1 10003 10143 CCCTAACCCTAACCCTAACCCTAACCCTAACCCTAACCCTAACCCTAACCCTAACCCTAACCCTAACCCTAACCCTAACCCTAACCCTAACCCTAACCCT,AACCCTACCCCTACCCCTAACCCTACCCCTACCCCTACCCCTACCCCTACCCCTACCCCTACCCCTACCCTAACCCTAACCCTAACCCTAACCCTAACCC chr1 10358 10428 ACCCTAAACCCTAACCCTAACCCTAACCCTAACCCCTAACCCCTAACCCTAACCCTAACCCTAACCCTAACCCGAACCCGAACCCGAACCCGAACCCTAG chr1 11780 11921 CGCAAATTTGCCGGATTTCCTTTGCTGTTCCTGCATGTAGTTTAAACGAGATTGCCAGCACCGGGTATCATTCACCATTTTTCTTTTCGTTAACTTGCCG,TTAAACGAGATTGCCAGCACCGGGTATCATTCACCATTTTTCTTTTCGTTAACTTGCCGTCAGCCTTTTCTTTGACCTCTTCTTTCTGTTCATGTGTATT chr1 11996 12101 TCTTCATCTGCAGGTGTCTGACTTCCAGCAACTGCTGGCCTGTGCCAGGGTGCAAGCTGAGCACTGGAGTGGAGTTTTCCTGTGGAGAGGAGCCATGCCT,ATCTGCAGGTGTCTGACTTCCAGCAACTGCTGGCCTGTGCCAGGGTGCAAGCTGAGCACTGGAGTGGAGTTTTCCTGTGGAGAGGAGCCATGCCTAGAGT chr1 12136 12347 TCTGCATGTAACTTAATACCACAACCAGGCGTAGGGGAAAGATTGGAGGAAAGATGAGTGACAGCATCAACTTCTCTCACAACCTAGGCCAGTAAGTAGT,TAAGTAGTGCTTCTGCTCATCTCCTTGGCTGTGATACGTGGCCGGCCCTCGCTCCAGCAGCTGGACCGCTACCTGCCGTCTGCTGCCATCGGAGCCCAAA,GCTCATCTCCTTGGCTGTGATACGTGGCCGGCCCTCGCTCCAGCAGCTGGACCCCTACCTGCCGTCTGCTGCCATCGGAGCCCAAAGCCGGGCTGTGACT,TCTCCTTGGCTGTGATACGTGGCCGGCCCTCGCTCCAGCAGCTGGACCGCTACCTGCCGTCTGCTGCCATCGGAGCCCAAAGCCGGGCTCTGACTGCTCA chr1 12400 12503 GCAGGTGGAAGATCAGGCAGGCCATCGCTGCCACAGAACCCAGTGGATTGGCCTAGGTGGGATCTCTGAGCTCAACAAGCCCTCTCTGGGTGGTAGGTGC,GGTGGAAGATCAGGCAGGCCATCGCTGCCACAGAACCCAGTGGATTGGCCTAGGTGGGATCTCTGAGCTCAACAAGCCCTCTCTGGGTGGTAGGTGCAGA chr1 12635 12779 CCTTCCCCAGCATCAGGTCTCCAGAGCTGCAGAAGACGACGGCCGACTTGGATCACACTCTTGTGAGTGTCCCCAGTGTTGCAGAGGTGAGAGGAGAGTA,GATGCCCGGCATGCCCTTCCCCAGCATCAGATCTCCAGAGAGGCAGAAGACGACGGCCGACTTGGATCACACTCTTGTGAGTGTCCCCAGTGTTGCAGAG,CTTGGATCACACTCTTGTGAGTGTCCCCAGTGTTGCAGAGGTGAGAGGAGAGTAGACAGTGAGTGGGAGTGGCGTCGCCCCTAGGGCTCTACGGGGCCGG chr1 12819 12919 CACCCTCTTGATCTTCCCTGTGATGTCATCTGGAGCCCTGCTGCTTGCGGTGGCCTATAAAGCCTCCTAGTCTGGCTCCAAGGCCTGGCAGAGTCTTTCC chr1 13039 13139 AACCAGTCCATAGGCAAGCCTGGCTGCCTCCAGCTGGGTCGACAGACAGGGGCTGGAGAAGGGGAGAAGAGGAAAGTGAGGTTGCCTGCCCTGTCTCCTA chr1 13165 13287 TGCACTGTTGGGGAGGCAGCTGTAACTCAAAGCCTTAGCCTCTGTTCCCACGAAGGCAGGGCCATCAGGCACCAAAGGGATTCTGCCAGCATAGTGCTCC,TAACTCAAAGCCTGAGCCTCTGTTCCCACGAAGGCAGGGCCATCAGGCACCAAAGGGATTCTGCCAGCATAGTGCTCCTGGACCAGTGATACACCCGGCA chr1 13561 13731 CAGGGATCCTGCTACAAAGGTGAAACCCAGGAGAGTGTGGAGTCCAGAGTGTTGCCAGGACCCAGGCACAGGCATTAGTGCCCGTTGGAGAAAACAGGGG,CAGGCATTAGTGCCCGTTGGAGAAAACGGGAATCCCGAAGAAATGGTGGGTCCTGGCCATCCGTGAGATCTTCCCAGGGCAGCTCCCCTCTGTGGAATCC chr1 14025 14125 TTCTATCTCCCTGGCTTGGTGCCAGTTCCTCCAAGTCGATGGCACCTCCCTCCCTCTCAACCACTTGAGCAAACTCCAAGACATCTTCTACCCCAACACC chr1 14221 14340 CATCTGCAACAGCTGCCCCTGCTGACTGCCCTTCTCTCCTCCCTCTCATCCCAGAGAAACAGGTCAGCTGGGAGCTTCTGCCCCCACTGCCTAGGGACCA,TGCTGACTGCCCTTCTCTCCTCCCTCTCATCCCAGAGAAACAGGTCAGCTGGGAGCTTCTGCCCCCACTGCCTAGGGACCAACAGGGGCAGGAGGCAGTC chr1 14440 14715 CTCTGGAAGCCTCTTAAGAACACAGTGGCGCAGGCTGGGTGGAGCCGTCCCCCCATGGAGCACAGGCAGACAGAAGTCCCCGCCCCAGCTGTGTGGCCTC,CCTCAAGCCAGCCTTCCGCTCCTTGAAGCTGGTCTCCACACAGTGCTGGTTCCGTCACCCCCTCCCAAGGAAGTAGGTCTGAGCAGCTTGTCCTGGCTGT,AAGCCAGCCTTCCGCTCCTTGAAGCTGGTCTCCACACAGTGCTGGTTCCGTCACCCCCTCCCAAGGAAGTAGGTCTGAGCAGCTTGTCCTGGCTGTGTCC,CACCCCCTCCCAAGGAAGTAGGTCTGAGCAGCTTGTCCTGGCTGTGTCCATGTCAGAGCAACGGCCCAAGTCTGGGTCTGGGGGGGGAGGTGTCATGGAG,CCCCTCCCAAGGAAGTAGGTCTGAGCAGCTTGTCCTGGCTGTGTCCATGTCAGAGCAACGGCCCAAGTCTGGGTCTGGGGGGGAAGGTGTCATGGAGCCC,TGAGCAGCTTGTCCTGGCTGTGTCCATGTCAGAGCAACGGCCCAAGTCTGGGTCTGGGGGGGAAGGTGTCATGGAGCCCCCTACGATTCCCAGTCGTCCT chr1 14805 15172 CCCCAGGTCCTTTCCCAGAGATGCCTGGAGGGAAAAGGCTGAGTGAGGGTGGTTGGTGGGAAACCCTGGTTCCCCCAGCCCCCGGAGACTTAAATACAGG,AAAAGGCTGAGTGAGGGTGGTTGGTGGGAAACCCTGGTTCCCCCAGCCCCCGGAGACTTAAATACAGGAAGAAAAAGGCAGGACAGAATTACAAGGTGCT,TTACAAGGTGCTGGCCCAGGGCGGGCAGCGGCCCTGCCTCCTACCCTTGCGCCTCATGACCAGCTTGTTGAAGAGATCCGACATCAAGTGCCCACCTTGG,GGCGGGCAGCGGCCCTGCCTCCTACCCTTGCGCCTCATGACCAGCTTGTTGAAGAGATCCGACATCAAGTGCCCACCTTGGCTCGTGGCTCTCACTGCAA,CTACCCTTGCGCCTCATGACCAGCTTGTTGAAGAGATCCGACATCAAGTGCCCACCTTGGCTCGTGGCTCTCACTGCAACGGGAAAGCCACAGACTGGGG,TGAAGAGTTCAGTCACATGCGACCGGTGACTCCCTGTCCCCACCCCCATGACACTCCCCAGCCCTCCAAGGCCACTGTGTTTCCCAGTTAGCTCAGAGCC,TTCAGTCACATGCGACCGGTGACTCCCTGTCCCCACCCCCATGACACTCCCCAGCCCTCCAAGGCCACTGTGTTTCCCAGTTAGCTCAGAGCCTCAGTCG chr1 15250 15350 CAGGGTGTGCAGCACCACTGTACGATGGGGAAACTGGCCCAGAGAGGTGAGGCAGCTTGCCTGGGGTCACAGAGCAAGGCAAAAGCAGCGCTGGGTACAA chr1 15470 15603 AAATATCTCAGGAGGCTGCAGTGGCTGACCATTGCCTTGGACCGCTCTTGGCAGTCGAAGAAGATTCTCCTGTCAGTTTGAGCTGGGTGAGCTTAGAGAG,GCCTTGGACCGCTCTTGGCAGTCGAAGAAGATTCTCCTGTCAGTTTGAGCTGGGTGAGCTTAGAGAGGAAAGCTCCACTATGGCTCCCAAACCAGGAAGG chr1 15924 16065 CACTTCCCTGGGAGCTCCCTGGACTGGAGCCGGGAGGTGGGGAACAGGGCAAGGAGGAAAGGCTGCTCAGGCAGGGCTGGGGAAGCTTACTGTGTCCAAG,GAACAGGGCAAGGAGGAAAGGCTGCTCAGGCAGGGCTGGGGAAGCTTACTGTGTCCAAGAGCCTGCTGGGAGGGAAGTCACCTCCCCTCAAACGAGGAGC chr1 16155 16255 CAGATACTCCCTGCTTCCTCTCTAGCCCCCACCCTGCAGAGCTGGACCCCTGAGCTAGCCATGCTCTGACAGTCTCAGTTGCACACACGAGCCAGCAGAG chr1 16314 16438 AATGAAAAATGTGTTGCTGTAGTTTGTTATTAGACCCCTTCTTTCCATTGGTTTAATTAGGAATGGGGAACCCAGAGCCTCACTTGTTCAGGCTCCCTCT,TGTTATTAGACCCCTTCTTTCCATTGGTTTAATTAGGAACGGGGAACCCAGAGCCTCACTTGTTCAGGCTCCCTCTGCCCTAGAAGTGAGAAGTCCAGAG chr1 16561 16661 ACTGAGCACACCAGAAATCAGGTGGCCTCAAAGAGCTGCTCCCACCTGAAGGAGACGCGCTGCTGCTGCTGTCGTCCTGCCTGGCGCCTTGGCCTACAGG chr1 16945 17038 GCAATGTACATGAGGTCGTTGGCAATGCCGGGCAGGTCAGGCAGGTAGGATGGAACATCAATCTCAGGCACCTGGCCCAGGTCTGGCACATAGAAATAGT chr1 17372 17472 AGAGGCGACATGGGGGTCAGGCAAGCTGACACCCGCTGTCCTGAGCCCATGTTCCTCTCCCACATCATCAGGGGCACAGCGTGCACTGTGGGGTCCCAGG chr1 17525 17625 CTGTGTCTGATGCCCTGGGTCCCCACTAAGCCAGGCCGGGCCTCCCGCCCACACCCCTCGGCCCTGCCCTCTGGCCATACAGGTTCTCGGTGGTGTTGAA chr1 17634 17734 GGAGCTGACAGAGCTGATGTTGCTGGGAAGACCCCCAAGTCCCTCTTCTGCATCGTCCTCGGGCTCCGGCTTGGTGCTCACACACACAGGAAAGTCCTTC chr1 17908 18008 GCAGACCTGCAGGGCCCGCTCGTCCAGGGGGCGGTGCTTGCTCTGGATCCTGTGGCGGGGGCGTCTCTGCAGGCCAGGGTCCTGGGCGCCCGTGAAGATG chr1 18033 18133 GAGCAGGGTACTTGGCACTGGAGAACACCTGTGGACACAGGGACAAGTCTGAGGGGGTCCCAAGAGGCTCAGAGGGCTAGGATTGCTTGGCAGGAGAGGG chr1 18152 18252 GAGAAGAGAGCTCAAGGTACAGGTGGGCAGCAGGGCAGAGACTGGGCAGCCTCAGAGGCACGGGGAAATGGAGGGACTGCCCAGTAGCCTCAGGACACAG chr1 18264 18364 TACCTTGATGGCCTTCTTGCTGCCCTTGATCTTCTCAATCTTGGCCTGGGCCAAGGAGACCTTCTCTCCAATGGCCTGCACCTGGCTCCGGCTCTGCTCT chr1 18577 18742 TGCTGAGTTCCCTGCACTCTCAGTAGGGACAGGCCCTATGCTGCCACCTGTACATGCTATCTGAAGGACAGCCTCCAGGGCACACAGAGGATGGTATTTA,AGACAGCCTCCAGGGCACACAGAGGATGGTATTTACACATGCACACATGGCTACTGATGGGGCAAGCACTTCACAACCCCTCATGATCACGTGCAGCAGA chr1 19658 19758 TGGGAGTACCAGCAGGCACTCAAGCGGCTTAAGTGTTCCATGACAGACTGGTATGAAGGTGGCCACAATTCAGAAAGAAAAAAGAAGAGCACCATCTCCT chr1 19819 19966 CCTTCATCTGCTGTAAAGGGTCCTCCAGCACAAGCTGTCTTAATTGACCCTAGTTCCCAGGGCAGCCTCGTTCTGCCTTGGGTGCTGACACGACCTTCGG,CCCTAGTTCCCAGGGCAGCCTCGTTCTGCCTTGGGTGCTGACACGACCTTCGGTAGGTGCATAAGCTCTGCATTCGAGGTCCACAGGGGCAGTGGGAGGG chr1 20059 20320 CAATGAGCCCTGGAAAATTTCTGGAATGGATTATTAAACAGAGAGTCTGTAAGCACTTAGAAAAGGCCGCGGTGAGTCCCAGGGGCCAGCACTGCTCGAA,AAAATTTCTGGAATGGATTATTAAACAGAGAGTCTGTAAGCACTTAGAAAAGGCCGCGGTGAGTCCCAGGGGCCAGCACTGCTCGAAATGTACAGCATTT,CTTAGAAAAGGCCGCGGTGAGTCCCAGGGACCAGCACTGCTCGAAATGTACAGCATTTCTCTTTGTAACAGGATTATTAGCCTGCTGTGCCCGGGGAAAA,CATTTCTCTTTGTAACAGGATTATTAGCCTGCTGTGCCCGGGGAAAACATGCAGCACAGTGCATCTCGAGTCAGCAGGATTTTGACGGCTTCTAACAAAA,AGTGCATCTCGAGTCAGCAGGATTTTGACGGCTTCTAACAAAATCTTGTAGACAAGATGGAGCTATGGGGGTTGGAGGACAGAACATATAGGAAAACTCA,AGTGCATCTCGAGTCAGCAGGATTTTGACGGCTTCTAACAAAATCTTGTAGACAAGATGGAGCTATGGGGGTTGGAGGACAGAACATATAGGAAAACTCA chr1 20457 20627 AAGGGTAAGCTGGTTTCATGATCGAATCAAGGCTCAGACAATTTTTAAAGGCCAGAGGGTAGACTGCAATCACCAAGATGAAATTTACAAGGAACAAATG,CAAGGCTCAGACAATTTTTAAAGGCCAGAGGGTAGACTGCAATCACCAAGATGAAATTTACAAGGAACAAATGTGAAGCCCAACATTTAGGTTTTAAAAA,CCAAGATGAAATTTACAAGGAACAAATGTGAAGCCCAACATTTAGGTTTTAAAAATCAAGCGTATGAATACAGAAGGTGGAGGGAACTTGCTTTAGACGC chr1 20641 20741 GAAAGACCTGGAAACTTCTGTTAATTATAAGCTCAGTAGGGGCTAAAAGCATGTTAATCGGCATAAAAAGGCAATGAGATCTTAGGGCACACAGCTCCCC chr1 20754 20854 CCTTCATCCTTCTTTCAATCAGCAGGGACCGTGCACTCTCTTGGAGCCACCACAGAAAACAGAGGTGCATCCAGCACCACAGAAAACAGAGCCACCACAG chr1 21047 21139 AGTCTCTCCCCTGCCCCTGTCTCTTCCGTGCAGGAGGAGCATGTTTAAGGGGACGGGTTCAAAGCTGGTCACATCCCCACCGAAAAAGCCCATGGACAAC chr1 21177 21277 AAGTGGAGGAGGAGAGGTGGCGGTGCTCCCCACTCCACTGCCAGTCGTCACTGGCTCTCCCTTCCCTTCATCCTCGTTCCCTATCTGTCACCATTTCCTG chr1 21449 21549 CTCTTCTGTCCCATCCCTGCCCTGCTCAAAATCCAATCACAGCTCCCTAACACGCCTGAATCAACTTGAAGTCCTGTCTTGAGTAATCCGTGGGCCCTAA chr1 21834 22029 GCCACACTGAGGCCTCCCTCCAAGCCTGCAGCCCCCATTTCCAGACCCTGCCAGGGCAACCTGCATATCCACCTCCCTACCCTGCCCCCCTCTTCCAGGA,CCCATTTCCAGACCCCACCAGGGCAACCTGCATATCCACCTCCCTACCCTGCCCCCCTCTTCCAGGAGTCTGCCCTATGTGGAGTAAGCACGTGGTTTTC,CTGCATATCCACCTCCCTACCCTGCCCCCCTCTTCCAGGAGTCTGCCCTATGTGGAGTAAGCACGTGGTTTTCCTCTTCAGCAACTATTTCCTTTTTACT,CCCTATGTGGAGTAAGCACGTGGTTTTCCTCTTCAGCAACTATTTCCTTTTTACTCAAGCAATGGCCCCATTTCCCTTGGGGAATCCATCTCTCTCGCAG chr1 22061 22149 ACAGAGCTTCTCAGTCTAAGCCAAGTGATGTGTCATAGTCCCCTGGCCCCAGTAATGGATTCTGGGATAGACGTGAGGACCAAGCCAGGGGGGATGGGTG chr1 22242 22448 ACCACGAGAGCATGGCCTGTCTGGGAATGCAGCCAGACCCAAAGAAGCAAACTGACATGGAAGGAAAGCAAAACCAGGCCCTGAGGACATCATTTTAGCC,TGACATGGAAGGAAAGCAAAACCAGGCCCTGAGGACATCATTTTAGCCCTTACTCCGAAGGCTGCTCTACTGATTGGTTAATTTTTGCTTAGCTTGGTCT,GAAGGAAAGCAAAACCAGGCCCTGAGGACATCATTTTAGCCCTTACTCCGAAGGCTGCTCTACTGATTGGTTAATTTTTGCTTAGCTTGGTCTGGGGAGT,AAGCAAAACCAGGCCCTGAGGACATCATTTTAGCCCTTACTCCGAAGGCTGCTCTACTGATTGGTTAATTTTTGCTTAGCTTGGTCTGGGGAGTTCTGAC,CGAAGGCTGCTCTACTGATTGGTTAATTTTTGCTTAGCTTGGTCTGGGGAGTTCTGACAGGCGTGCCACCAATTCTTACCGATTTCTCTCCACTCTAGAC chr1 22512 22566 TTCATGCTAGAAGTTATCAATCAACCTCGCCCTAGGTGTTCCCTTCCCAGCCTCTAGGACACAGTGTCAGCCACATAATTGGTATCTCTTAAGGTCCAGC chr1 22748 22848 TCTCCTCATCCCATCCCTGGGCAGGGGACATGCAACTGTCTACAAGGTGCCAAGTACCAGGACAGGAAAGGAAAGACGCCAAAAATCCAGCGCTGCCCTC chr1 22870 22970 CCCATCTTGGCAAGGAAACACAATTTCCGAGGGAATGGTTTTGGCCTCCATTCTAAGTGCTGGACATGGGGTGGCCATAATCTGGAGCTGCTGGCTCTTA chr1 23130 23228 ATTTCCTGAAGGCTTCCTAGGTGCCAGGCACTGTTCCATTCCTTTGCATGTTTTGATTAATTTAATATTTAAAATAATTCTACCAGGAAGCTACCATTAT chr1 23250 23350 ACACCGAGGCTTAGAGGGGTTGGGTTGCCCAAGGTTACAGAGGAAGAAAACAGGGGAGCTGGATCTGAGCCAAGGCATCAACTCCAAGGTAACCCCTCAG chr1 23557 23615 CTGAGACAGGCGGACACATACGTCCCACTGGGGACTACCATGTGAGGCATGGTGTGGGAGCCTGGGAAGGAGACCAAGCCTCATTTCAGTTAGCTTATGG chr1 24000 24120 TGTCATTTCCTCACATCTGCCTTCCCGGCCCTGAGCCCAAGCCAGGCTTCCCATGACGAGCCTCACAGTACCCCATCTCCCCTGAACAGATGCAGTAATA,CCTCACAGTACCCCATCTCCCCTGAACAGATGCAGTAATAACCTACATAACCCGGGGCCATGATCTATGGCTTTGAATCCTGGCTCTGTCACTAGGCCAG chr1 24248 24612 TACAAAATATTATCAATAGACCTTGTCACAACTGTTATTGAAGAACTAATCATCTATTGCTTATTTAGGTCTTTCTCTCCTGCCAGAATGTGCGCTCCAG,ATCAATAGACCTTGTCACAATTGTTATTGAAGAACTAATCATCTATTGCTTATTTAGGTCTTTCTCTCCTGCCAGAATGTGCGCTCCAGGTGGAGAGGTA,TTTCTCTCCTGCCAGAATGTGCGCTCCAGGAGGAGAGGGATGTTGCCTTATCCGTGGCTGGGTATATAGAGATTCCCACACTGCCTTGCACACGAGCACT,GAGAGGTATGTTGCCTTATCCGTGGCTGGATATATAGAGATTCCCACACTGCCTTGCACACGAGCACTGCTGGGTAAATATTTGTTGGCTGCAGGAAAAC,TGGGTAAATATTTGTTGGCTGCAGGAAAACGTGAAGGAATAGGCCCTCCAATGGGAGGAAAAGCATGAGTTGTGAGAGCAGAGCCACCACAGGAAACCAG,GGAAACCAGGAGGCTAAGTGGGGTGGAAGGGAGTGAGCTCTCGGACTCCCAGGAGTAAAAGCTTCCAAGTTGGGCTCTCACTTCAGCCCCTCCCACACAG chr1 24683 24850 CTCCCAGAGGGTGTGTTGCTGGGATTGCCCAGGACAGGGATGGCCCTCTCATCAGGTGGGGGTGAGTGGCAGCACCCACCTGCTGAAGATGTCTCCAGAG,AGGACAGGGATGGCCCTCTCATCAGGTGGGGGTGAGTGGCAGCACCCACCTGCTGAAGATGTCTCCAGAGACCTTCTGCAGGTACTGCAGGGCATCCGCC,CTCCAGAGACCTTCTGCAGGTACTGCAGGGCATCCGCCATCTGCTGGACGGCCTCCTCTCGCCGCAGGTCTGGCTGGATGAAGGGCACGGCATAGGTCTG chr1 24921 25011 ATCAGAGCCACCCACGACCACCGGCACGCCCCCACCACAGGGCAGCGTGGTGTTGAGACAACACAGCCCTCATCCCAACTATGCACATAGCTTCAGCCTG chr1 25055 25291 GAGCGCATAGATGGGACTCTGCTGATGCCTGCTGAGTGAATGAGGGAAAGGGCAGGGCCCGGGACTGGGGAATCTGTAGGGTCAATGGAGGAGTTCAGAG,AGGGAAAGGGCAGGGCCCGGGACTGGGGAATCTGTAGGGTCAATGGAGGAGTTCAGAGAAGGTGCAACATTTCTGACCCCCTACAAGGTGCTTGCTACCT,GACCCCCTACAAGGTGCTTGCTACCTGCCAGGCACCCTTTCCATACCTTGTCTCAGTTCAGCTCCCCACCTTGGATAAACAAGAAACCTTGGTTGCAGAG,CTACCTGCCAGGCACCCTTTCCATACCGTGTCTCAGCTCAGCTCCCCACCTTGGATAAACAAGAAACCTTGGTTGCAGAGGAAAAAAGAGGCTGGAAACA chr1 25403 25740 TGAGGAATCTGAGGCCTGCTCCTGAAACAGACTGGGCAGTGGCTAGTGACTCTAGGTATAGGAGTATCCAGCCCTGCTCACCCAGGCTAGAGCTTAGGGG,TTAGGGGGCCAAGAGGAAAGAGGTGCCTGTGGGGGTGGAGGACAGGAAGGAAAAATACTCCTGGAATCGCAAAGTGAGGGCAGAGTCTATTTATATTGGG,GGAATTGCAAAGTGAGGGCAGAGTCTATTTATATTGGGTTTAATTAACTCCTCTCCCTGGTGCCACTAAAGCAGCAATCACACTGCAGACAGCACTGATT,GTGCCACTAAAGCAGCAATCACACTGCAGACAGCACTGATTTGATTGGCAAGAGATGCACCAGGCAGAATATTAAGGGACCAGGCCCCTATAAATAGGCC,CTGCAGACAGCACTGATTTGATTGGCAAGAGATGCACCAGGCAGAATATTAAGGGACCAGGCCCCTATAAATAGGCCTAATCACAGCCCCTCACTGGAAA chr1 25767 25867 GGCACTGTGCCCTAGACCTGCTCCCCTAGGCACTACAGTGGGGCCCTTGGTTGCACCACAAGTAGGTAGGGATGGATGAGTGTGGCATGAAGGGCCTAGG chr1 26053 26153 TTGCTCCCGCTGCTGGCTTCCCCAGCCCTCCCTTCTGCCCTCCTCAGGCCAGCACTTTTCAGTGAGTTCCTCCTTTGCATACAGGCTTTCCAGATCTGTA chr1 26406 26506 AGATGCAAGATATTTCCTGTGCACATCTTCAGATGAATTTCTTGTTAGTGTGTGTGTGTTTGCTCACACATATGCGTGAAAGAAGAGTACATACACAGAT chr1 26680 26883 TCAAATTAAATTCATTCTACTCCAGTCATGGGTACAAAGCTAAGGAGTGACAAATCCCTCTTGGAGTTAGGGGAGTCAGGAAAAAGCTCTTAGCAGAATG,ACAAAGCTAAGGAGTGACAAATCCCTCTTGGAGTTAGGGGAGTCAGGAAAAAGCTCTTAGCAGAATGTGTGCCTCTCGGCCGGGCGCAGCGGCTCACGCC,TCTTGGAGTTAGGGGAGTCAGGAAAAAGCTCTTAGCAGAATGTGTGCCTCTCGGCCGGGCGCAGCGGCTCACGCCTGTAATCCCAGCACTTTGGGAGGCG,CCCTCTCGGCCGGGCGCAGCGGCTCACGCCTGTAATCCCAGCACTTTGGGAGGCGAAGGCAGGCAGATCACCTGAGGTCGGGAGTTCGAGACCAGTCTGA chr1 27102 27252 AAAGAAACAGCTTGAACAAAAAGTGTGTAGGGGAACCGCAAGCGGTCTTGAGTGCTGAGGGTACAATCATCCTTGGGGAAGTACTAGAAGAAAGAATGAT,AAAGTGTGTAGGGGAACCGCAAGCGGTCTTGAGTGCTGAGGGTACAATCATCCTTGGGGAAGTACTAGAAGAAAGAATGATAAACAGAGGCCAGTTTGTT,AGTGCTGAGGGTACAATCATCCTTGGGGAAGTACTAGAAGAAAGAATGATAAACAGAGGCCAGTTTGTTAAAAACACTCAAAATTAAAGCTAGGAGTTTG chr1 27582 27785 ATGCCAAAGAAATGAGTCTCTGCTGTTTTTGGGCAGCAGATATCCTAGAATGGACTCTGACCTAAGCATCAAAATTAATCATCATAACGTTATCATTTTA,CCTAGAATGGACTCTGACCTAAGCATCAAAATTAATCATCATAACGTTATCATTTTATGGCCCCTTCTTCCTATATCTGGTAGCTTTTAAATGATGACCA,TTAATCATCATAACGTTATCATTTTATGGCCCCTTCTTCCTATATCTGGTAGCTTTTAAATGATGACCATGTAGATAATCTTTATTGTCCCTCTTTCAGC,CCCCTTCTTCCTATATCTGGTAGCTTTTAAATGATGACCATGTAGATAATCTTTATTGTCCCTCTTTCAGCAGACGGTATTTTCTTATGCTACAGTATGA chr1 27995 28187 TATTGATATGTTTTGTTGTTTTCATGCAATAATGCAAATCTTAGCCCAAACATTTTGTTAGTAGTACCAACTGTAAGTCACCTTATCTTCATACTTTGTC,GCAATAATGCAAATCTTAGCCCAAACATTTTGTTAGTAGTACCAACTATAAGTCACCTTATCTTGATACTTTGTCTTTATGTAAACCTAAATTAGATCTG,ATGCAAATCTTAGCCCAAACATTTTGTTAGTAGTACCAACTGTAAGTCACCCTATCTTCATACTTTGTCTTTATGTAAACCTAAATTAGATCTGTTTTTG,AAACATTTTGTTAGTAGTACCAACTGTAAGTCACCTTATCTTCATACTTTGTCTTTATGTAAACCTAAATTAGATCTGTTTTTGATACTGAGGGAAAAAC,GTAGTACCAACTGTAAGTCACCCTATCTTCATACTTTGTCTTTATGTAAACCTAAATTAGATCTGTTTTTGATACTGAGGGAAAAACAAGGGAATCTAAC,CCTTTGTCTTTATGTAAACCTAAATTAGATCTGTTTTTGATACTGAGGGAAAAACAAGGGAATCTAACACTAACCAGCCCGTAGTGTGTGGTCAACACTT chr1 28198 28298 GTATACATCACCCCAATTGTTTGTCTTCACCACACACTTTGGAGTTAGGTAGCAGTATCTATTTTTACAAATAAGAAAACCCAGGCACAAAGGAGTTGAT chr1 28439 28545 TCTTCTATCAGGGAGTTTTATGAGAAACCCTAGCTCCTCAGTTCCACAGTGGGTAACTGTAATTCATTCTAGGTCTGCGATATTTCCTGCCTATCCATTT,GGAGTTTTATGAGAAACCCTAGCTCCTCAGTTCCACAGTGGGTAACTGCAATTCATTCTAGGTCTGCGATATTTCCTGCCTATCCATTTTGTTAACTCTT chr1 28577 28674 AATAATGGTGGTTTGGTTTTTTTTTTTTTGCATCTATGAAGTTTTTTCAAATTCTTTTTAAGTGACAAAACTTGTACATGTGTATCGCACAATATTTCTA chr1 28679 28808 CAGCACTGCTTTCGAGAATGTAAACCGTGCACTCCCAGGAAAATGCAGACACAGCACGCCTCTTTGGGACCGCGGTTTATACTTTCGAAGTGCTCGGAGC,CACTCCCAGGAAAATGCAGACACAGCACGCCTCTTTGGGACCGCGGTTTATACTTTCGAAGTGCTCGGAGCCCTTCCTCCAGACCGTTCTCCCACACCCC chr1 29089 29191 AAGCTCCGGGGCGAGCCCAAGACGCCTCCCGGGCGGTCGGGGCCCAGCGGCGGCGTTCGCAGTGGAGCCGGGCACCGGGCAGCGGCCGCGGAACACCAGC,GCTCCGGGGCGAGCCCAAGACGCCTCCCGGGCGGTCGGGGCCCAGCGGCGGCGTTCGCAGTGGAGCCGGGCACCGGGCAGCGGCCGCGGAACACCAGCTT chr1 29331 29431 CCTCCCGGAAGCTCCCGCCGCCGCTTCCGCTCTGCCGGAGCCGCTGGGTCCTAGCCCCGCCGCCCCCAGTCCGCCCGCGCCTCCGGGTCCTAACGCCGCC chr1 29686 29786 TGTCCGCCAACCTCGGCTCCTCCGGGCAGCCCTCGCCCGGGGTGCGCCCCGGGGCAGGACCCCCAGCCCACGCCCAGGGCCCGCCCCTGCCCTCCAGCCC chr1 30409 30509 CGTAGCATAAATATGTCCCAAGCTTAGTTTGGGACATACTTATGCTAAAAAACATTATTGGTTGTTTATCTGAGATTCAGAATTAAGCATTTTATATTTT chr1 30809 30909 GGGGTGGGGCCCTCATTATAGATCTGGTAAGAAAAGAGAGCATTGTCTCTGTGTCTCCCTCTCTCTCTCTCTCTCTCTCTCTCATTTCTCTCTATCTCAT chr1 31781 31881 ATATGCTCCACGATGCCTGTGAATATACAAACACACCACATCATATACCAAGCCTGGCTGTGTCTTCTCACAAATGCACTGCTAGGCACCACCCCCAGTT chr1 32173 32273 CTCCTGGATTTGCCAGGATCCAAGAGCATGGACTTTAGGAATTCCTGGTGGAGGAGTGAAGAAAATGTGACAGGGTGTCCTAAGCCCCGATCTACAGGAA chr1 32519 32619 TGAGGTTTCTAATGTATTTGAAAGAGGCCTGGGTCTAGAAGTCTACCCAGAGGGCTCTGTGTTGTGCACGCTAAGATAAGAACCTTCCCTGTGGGAGTTC chr1 32732 32832 CAGCCCAGGAACCTCCCCTTATCGGAAATGAACAGCATTTGAAGCTTCACCAGACAGACCAGACAGCTTAGCCCTCGTGTTGTGCCATGTGGGTTGTTCT chr1 32926 33120 TGATCCTAGGCATGTTACCTGTGCCTCAGTTTTCACTCTGTCAATATGTAATAACTGAATCTGTCTTTGTGGTGAGGATTCAGTGAGTTAACATATTTGA,ATTTGAAGTGCTTAAAAATGAGGCTTGTGTCCACAGATTAATGAGTGAATACACAAATGGTGATATGGACATACAGTGGAGTATTAGTCATAAAAAGGAA chr1 33143 33289 TGTGACAGAACCTCAAAAGCATTAGGTTAAGTGGAAGAAGCCAGACACAGGTCACCTATTGTGTAATTCCATTTATAGGAAATATACAGAATATGTAAAT,TGTAAATCCGTGGAGAAAGAAAGCCGATTTCCAGGGGCTAAGGGGAGGGGAGACTGGGAAGAGGCTGACTCATGGGGAGAAGGATTCAGTTTGAGGAGGT chr1 33449 33669 TTTTACCCCCATTAAAAAAAAAAAAAAAAGGACCAGATGTGGTTGCTCACACCCATAATCCCAACACTTTGGAAAAAGGTGAAAGATTTTTTTTTTCTTT,ATAATCCCAACACTTTGGAAAAAGGTGAAAGATTTTTTTTTTCTTTTTTTTTATATACTTAAGTTCTAGGGTACATGTGCATAATGTGCAGGTTGGATAC,ATAATGTGCAGGTTGGATACATAGATATGCGTGTGCCATGTTGGTTTGCTGCACCCATCAACTTGTCATTTACATTAGGTATTTCTCCTAATGCTATCCC chr1 33842 33931 AAAGGACATGAACTCATCCTTTTTAATGGCTGCATAGTATCCCATGGAATATATGTGCCACATTCTCTTAATCCAGTCTGTCATTGATGGACTTTTGGGT chr1 33933 34044 GGACATTTGGGGTGGTTCAAAGTCTTTGCTATTGTGAATACTGCCACAATAAACATCCATGTGCATGTGTCTTTATAGTAGCACGATTTATAATCCTTTT,GTTCAAAGTCTTTGCTATTGTGAATACTGCCACAATAAACATACATGTGCATGTGTCTTTATAGTAGCACGATTTATAATCCTTTTGGTATATACCCTAA chr1 34070 34162 GTAAAGAGACATTTATAGCACTAAATGCCCACAAGAGACCTCTGCCTGAGAACGTGGGTTTCAGCCTAAGAGTTGTAATATGTGTGCCCATTCACAGGTG chr1 34268 34451 GAATCTCCACCCAGCGACTTGCTCTCACATCTTCTTGGCCAGCACTGGACCACACAACTCCTTCTAGATACAGAGGAGTCCTAGGATTCTATGAGAAAGA,GGATTCTATGAGAAAGAAGGGGAGGGTGGGCAAAGGGCAGCCAGCTGTGCAGCATCTGCTGGAGACACCTAACCCTTGGTGGAGGGGTTGTGGTGCTGGG chr1 34511 34606 TTACCCTGGTGAAGCAGGGCAGGGTTACAAGCATTCCAGCAACATGAAGCAGCAGGAGTGTTTTAATTAAAAGAAGGCAGTTGCTGTAACCAACTATAAA chr1 35413 35513 TGAGGTGGGAGGATCGCTTGAGGCCAGGAGTTCAAGACCAGCCTGAGCAACATAGTGAGACTTTGTCTCTATAAAAAATAAATAAATAAATAAAAACAAC chr1 35792 35892 TGGCTCTCCCAGGTGAGAGAGGACTCCATTTTCACAGGCAGGCGTGGGAGCTTCAGCACCCATCTCTGGGCCCAGAATGACCCACTGGAGACCTTACAGC chr1 36101 36201 AGGACTAATCCTTGGAACAGCTCAGGGAGGATTATCCCAGCCACTGTCAGCAGCGGTGCAGCTGGCTCATTCCCATATAGGGGGAGGCCAGAGCCAGGGG,GGACTAATCCTTGGAACAGCTCAGGGAGGATTATCCCAGCCACTGTCAGCAGCGGTGCAGCTGGCTCATTCCCATATAGGGGGAGGCCAGAGCCAGGGGC chr1 36528 36625 CTTTCCCACCCAAGTGCTGGCATCCTCCCTGTCCTGCTTCACCTGAGACACCCCTTGTCTCATTAGACATGCAACTACGGGAGGGGTGACAGGAAGACAA,CCTCAAACCTCTACCACCCAAGTGCTGGCATCCTCCCTGTCCTGCTTCACCTGAGACCCCCCTTGTCTCATTAGACATGCAACTACGGGAGGGGTGACAG chr1 37129 37229 GTGAAATCTAAGTGCAGATCCCATATTTCCAATAAAAAGGTAACATCCAAACTCAGATGTCCTATGAGTATAAAATACACAAAGATCTTCTGGACTTAGT chr1 37516 37616 AGGGCAGGGCCAAGGGCGGCTTGGTGGGGTGGGGATGGGATGCACAGAGATAACTCCAACCCTTAAGAAGGTGTTTCCTAGAGCAGGCTGTGACCTGTCA chr1 37904 37996 TTAAGGAGGGGAGACCAGGTCCTGAGTAAAGTTGAAGGGGAGGGGCTGAGTCCTGCTAGCCAGGAGTCTCATCCCCTGGGGAAGTTCCAGGGACCCCTCA chr1 38283 38380 GGCTCGGAGGACTCGCCACTGCTCAAAGGCAGTGAGGATTTTCGCACTAGAAGCTGGAGGACAGGGATCCTTGTTAGGTAGGAGCAGAAAGCTTAGAAAA chr1 38609 38709 AGATGCTGAAATTAACAAATGGCTTCTGAGCATGTGGCATAGGGTGTAACTGTACAGTCTTTTGTGATTATGCATAAAGATCAAAGGATGGGAGTAGCAA chr1 38980 39088 GGACAGAGTGCAAAATGAAAGAAGACTGTCAGAGACCCCAAACTCTGCTGTCAAGAAGAAGGCTGATAAAACTACTTGGCTGCAAACACGTGGATCTTTC,TGCAAAATGAAAGAAGACTGTCAGAGACCCCAAACTCTGCTGTCAAGAAGAAGGCTGATAAAACTACTTGGCTGCAAACACGTGGATCTTTCGTGAGAAA chr1 39099 39199 CCAGAGGCAGAAGCCCAGAAGGCAGAGCCAAGAGACATGGAATCTTCCCACATCTTAAAACCTGTTTAGGGAACACCAGCATCTGTCCAGCTGGATTTCA chr1 39418 39585 GTTTTGCATGCACAAGGGACAGGAGTCTTGGGGACAGAGGACAGGCTGTGGTGGCAGATACTAAGGTGACCCCCCACAACCCCCACCTCTGCCATTCACA,GACCCCCCACACCCCCCACCTCTGCCATTCACACCCTTGAATAATCCCCTTCTCTGGTTGTAAGCAGAACCTGTGGCTTGCTTATGAAGGAGGCGGTATA,TCCCCTTCTCTGGTTGTAAGCAGAACCTGTGGCTTGCTTATGAAGGAGGCGGTATATATGTGATTCATGTACTGATCATATTGTATAAGATCACTGGCTG chr1 39920 40020 AAAATGTTAAGATCATAACCTGTCTTTCTGGGGACTCTCTCTTGACGCCTTTGAAGAAGCAGGCTGCCATGTTGCAAGCTGCCTCATGGAGGGGATCAGC chr1 43646 43746 TGCTATTTCTATTCCATATCGTACTAAAAGTCCTAGCCAGGACAATTAGACAAAATAAAAATAAAAACACCCAAATTGGAAAGATAGAAGCAAACTTTTC chr1 43974 44074 ACCAAACATCTGTACACTAAAAACTATAAAACATTGAAAAAAGAAGTTGAATAAGACACATATAAATAGAAAGCTATCTCATGTTAATAGATTAGAAAAA chr1 44085 44185 AAGATGTCCTCACTACTTAAAGCAATTTATAGATCTAATGCATTTATTGCAATCTCTTCAAAATCCCAAAGGTATTTTTGACAGAAATAAAAAAAAAATT chr1 44304 44504 CAAAGCAACATGATACTGTCATAAAAACACACAGATAAACCTATGGAATGGAATAAAGAGCACAGAAATAAGTCCACACATTTACATTCAATTGATTTTC,AACAACAATGTCAAGAAGACAATGGGGAAAAGACAATCTCTTCAATAAATGATGCTGGAAAAACTATATATCCACATGCAGAAGAATGCAGTTGAATCCT chr1 44688 44788 GCCAAATTAAAAAATTTCTAACAACAAAAGAAACGATCAATAGAGTGAAAAAGATAACCTCTTGAATGGGAGAAATATTTGCAAACTACTCATCCAACCG chr1 45372 45472 GAAATAAGCTAGACACAGAAAGACAAATATTGCATGATCTCACTTAGAATCTAAAAAATCTGAACTCATAGAAGCAGAGAATAGTATGATGGTTACTAGG chr1 45738 45867 TCAATTAAAAAATAATTTTTAAAAATGAGAAACAAAAAAGCTGACATTTTCAGATTAAAAAAATTATACAGAAGAATTAATTCATTAAAGTAAAAACAAA,AAAATAATTTTTAAAAATGAGAAACAAAAAAGCTGACATTTTCAGATTAAAAAAATTATACAGAAGAATTAATTCATTAAAGTAAAAACAAATGTGGGAA,AAACAAAAAAGCTGACATTTTCAGATTAAAAAAATTATACAGAAGAATTAATTCATTAAAGTAAAAACAAATGTGGGAAAATGGTTTTTAAATATAATTT chr1 46111 46212 AGCTTGATGGTGGTCACTGTTTCACGATAAATATACATATGTATCAAAACATCACATTACACACCATAAAGATATATAACTTGTTATCAAAAAGAAATAT,GCTTGATGGTGGTCACTGTTTCACGATAAATATACATATGTATCAAAACATCACATTACACACCATAAAGATATATAACTTGTTATCAAAAAGAAATATA chr1 47250 47346 ATGATAAATTTTGGAATAGTTAACAGATGATAAAAGTGTTGTTTTCAGTCATCCCTATCCAATGAAGTAAAAAAAAAAGTGTTGAATGGGAAGAAATCAA chr1 47593 47693 TAACTCTTCTGATATTTTTTCTCTTGAGAAAATTAATATGACTCATAGATCTGGTTCCCAAGAGAAATCAATGGAGGCCTGGTTACAAGGATCTAAGAAG chr1 47820 47920 AGTGTCACTACTGCACACCCTGGAACAGAACAGGTAGGTCAGAAAAACGCTCCCAAAGTTTAGCAATGTCAAGGCAATCTCTCTCTTCTTACATTTCCCT chr1 48088 48193 ATAAGGATCTGTTATCTCTTGTCACCTTCCTTATGTCATATGATATGTCACATTTCCCACTGCGGAGACCAAACATGTTCACATCGTGTGCGTTCCATTT,GATCTGTTATCTCTTGTCACCTTCCTTATGTCATATGATATGTCACATTTCCCACTGCGGAGACCAAACATGTTCACATCGTGTGCGTTCCATCTTCCTA chr1 48445 48677 AACGGGCAAAGATTTCATGACAAAGACACGGAAACCAATCACAACAAAAGCAAAAATTGAGAAGTGGAATCTAATAAAACAATAGCTTCTGCACAGCAAA,ACCAATCACAACAAAAGCAAAAATTGAGAAGTGGAATCTAATAAAACAATAGCTTCTGCACAGCAAAAGAAGCTACCAACAAAGTAAACAGACAACCTAC,CAGAATGGGAGAAAATATTTGCCAACTGTAAGTCTGACAAAAATCTAATATCTGGCAGCTATAAGGAACTTAAATTTACAAGACAAAAACAACCCCATTA chr1 48681 48781 GTGGGCAAAGAACATGAATAGACACTCTCAAAAAAAGATATACATATGGTTAACAAGCATATGAAAAAAAAGCTCAATATACTGAGCATTAGAGAAATGC chr1 48832 48932 TTAAAAAGTCAAAAATAACAGATATCGGTGAGGTTACAGAGAAAAGGGAACACTTATACACTGTTGGTGGGACTGTAAATTATTTCAACCATTGTGGAAA chr1 48967 49067 ACAGAACTATCATTCAACCCAGCAATTCCATTACTGGGTATATACCCAGAAGAATATAAATCGTTCTACCATAAAGACGCATGCATGAGAATGTTCATTG chr1 49092 49192 ATGGAATCAACTTAAATGCCCATCAGTAACAGACTGGATAAAGAAAGTGTGGTACAGATACACCGTGGATTACTATGCAGCCATAAAAAAGAACAAGATC chr1 10003 10143 FCC1MK2ACXX:2:2110:4301:28831#/1,FCC1MK2ACXX:2:2110:4301:28831#/2 chr1 10358 10428 FCC21NUACXX:5:2103:2764:46055#/2 chr1 11780 11921 FCC1MK2ACXX:2:1105:2715:51181#/1,FCD243JACXX:5:1216:17736:35719#/1 chr1 11996 12101 FCC1MK2ACXX:2:2304:9851:96789#/1,FCD243JACXX:5:2314:4768:97687#/2 chr1 12136 12347 FCC1MK2ACXX:2:1105:2715:51181#/2,FCD243JACXX:5:1301:1537:86102#/1,FCD243JACXX:5:1216:17736:35719#/2,FCC21NUACXX:5:1212:12308:57061#/1 chr1 12400 12503 FCC1MK2ACXX:2:2304:9851:96789#/2,FCD243JACXX:5:2314:4768:97687#/1 chr1 12635 12779 FCD243JACXX:5:1301:1537:86102#/2,FCC21NUACXX:5:1212:12308:57061#/2,FCC21NUACXX:5:1112:9784:5716#/1 chr1 12819 12919 FCC21NUACXX:5:2206:3702:42671#/1 chr1 13039 13139 FCC21NUACXX:5:1112:9784:5716#/2 chr1 13165 13287 FCC1MK2ACXX:2:2303:7698:86735#/1,FCC21NUACXX:5:2206:3702:42671#/2 chr1 13561 13731 FCC1MK2ACXX:2:2303:7698:86735#/2,FCC21NUACXX:5:2314:9596:94920#/2 chr1 14025 14125 FCC21NUACXX:5:2314:9596:94920#/1 chr1 14221 14340 FCC1MK2ACXX:1:1102:8457:72597#/1,FCC1MK2ACXX:2:2112:4058:13620#/1 chr1 14440 14715 FCC21NUACXX:5:1111:11242:55963#/2,FCC1MK2ACXX:1:1305:10748:71369#/1,FCC1MK2ACXX:2:1301:6022:22944#/1,FCC21NUACXX:5:2302:8976:47710#/1,FCC1MK2ACXX:2:2112:4058:13620#/2,FCC1MK2ACXX:1:1102:8457:72597#/2 chr1 14805 15172 FCC21NUACXX:5:1111:11242:55963#/1,FCC1MK2ACXX:1:2312:10383:17891#/1,FCC1MK2ACXX:2:1301:6022:22944#/2,FCC1MK2ACXX:1:1305:10748:71369#/2,FCC21NUACXX:5:2302:8976:47710#/2,FCD243JACXX:5:2101:5803:26445#/2,FCD243JACXX:5:1306:3361:79162#/1 chr1 15250 15350 FCC1MK2ACXX:1:2312:10383:17891#/2 chr1 15470 15603 FCD243JACXX:5:2101:5803:26445#/1,FCD243JACXX:5:1306:3361:79162#/2 chr1 15924 16065 FCC1MK2ACXX:2:2307:8459:94884#/2,FCC21NUACXX:5:2306:5997:33003#/1 chr1 16155 16255 FCC1MK2ACXX:1:2113:15434:7030#/2 chr1 16314 16438 FCC1MK2ACXX:2:2307:8459:94884#/1,FCC21NUACXX:5:2306:5997:33003#/2 chr1 16561 16661 FCC1MK2ACXX:1:2113:15434:7030#/1 chr1 16945 17038 FCD243JACXX:5:1116:14466:64207#/2 chr1 17372 17472 FCD243JACXX:5:1116:14466:64207#/1 chr1 17525 17625 FCC1MK2ACXX:2:1103:5984:72352#/1 chr1 17634 17734 FCC21NUACXX:5:2308:4380:13608#/1 chr1 17908 18008 FCC1MK2ACXX:2:1103:5984:72352#/2 chr1 18033 18133 FCC21NUACXX:5:2308:4380:13608#/2 chr1 18152 18252 FCC1MK2ACXX:1:2312:1386:94004#/1 chr1 18264 18364 FCC1MK2ACXX:2:2202:3770:94682#/2 chr1 18577 18742 FCC1MK2ACXX:1:2312:1386:94004#/2,FCC1MK2ACXX:2:2202:3770:94682#/1 chr1 19658 19758 FCC21NUACXX:5:2304:1410:22583#/2 chr1 19819 19966 FCD243JACXX:5:1211:5529:13528#/2,FCC21NUACXX:5:1203:9494:8389#/2 chr1 20059 20320 FCC21NUACXX:5:2304:1410:22583#/1,FCC1MK2ACXX:1:1208:13559:62335#/2,FCC21NUACXX:5:2305:4114:54016#/1,FCC21NUACXX:5:2310:12288:39217#/2,FCC21NUACXX:5:1203:9494:8389#/1,FCD243JACXX:5:1211:5529:13528#/1 chr1 20457 20627 FCC1MK2ACXX:1:1208:13559:62335#/1,FCC21NUACXX:5:2305:4114:54016#/2,FCC21NUACXX:5:2310:12288:39217#/1 chr1 20641 20741 FCC21NUACXX:5:2202:3364:43471#/2 chr1 20754 20854 FCD243JACXX:5:1109:11059:8948#/2 chr1 21047 21139 FCC21NUACXX:5:2202:3364:43471#/1 chr1 21177 21277 FCD243JACXX:5:1109:11059:8948#/1 chr1 21449 21549 FCC21NUACXX:5:2102:15551:71760#/1 chr1 21834 22029 FCC21NUACXX:5:2102:15551:71760#/2,FCC21NUACXX:5:1213:10990:48576#/1,FCC1MK2ACXX:1:1204:5539:11398#/1,FCD243JACXX:5:2310:5628:73793#/2 chr1 22061 22149 FCD243JACXX:5:1310:4328:99408#/2 chr1 22242 22448 FCC21NUACXX:5:1213:10990:48576#/2,FCC21NUACXX:5:2213:17167:65551#/2,FCC21NUACXX:5:2213:17167:65551#/1,FCC1MK2ACXX:1:1204:5539:11398#/2,FCD243JACXX:5:2310:5628:73793#/1 chr1 22512 22566 FCD243JACXX:5:1310:4328:99408#/1 chr1 22748 22848 FCC1MK2ACXX:1:2305:2692:50678#/2 chr1 22870 22970 FCC1MK2ACXX:2:2214:11805:76913#/1 chr1 23130 23228 FCC1MK2ACXX:1:2305:2692:50678#/1 chr1 23250 23350 FCC1MK2ACXX:2:2214:11805:76913#/2 chr1 23557 23615 FCC1MK2ACXX:2:1114:5825:36701#/2 chr1 24000 24120 FCC1MK2ACXX:2:1114:5825:36701#/1,FCD243JACXX:5:2201:8592:8770#/1 chr1 24248 24612 FCD243JACXX:5:2315:13027:60427#/1,FCC1MK2ACXX:2:1209:11103:92852#/1,FCD243JACXX:5:1312:20719:89268#/1,FCC1MK2ACXX:2:1209:11103:92852#/2,FCD243JACXX:5:2201:8592:8770#/2,FCC1MK2ACXX:1:2310:10881:15393#/1 chr1 24683 24850 FCD243JACXX:5:2315:13027:60427#/2,FCC21NUACXX:5:2112:11980:18488#/2,FCD243JACXX:5:1312:20719:89268#/2 chr1 24921 25011 FCC1MK2ACXX:1:2310:10881:15393#/2 chr1 25055 25291 FCC21NUACXX:5:2112:11980:18488#/1,FCD243JACXX:5:2206:12649:46794#/1,FCC21NUACXX:5:2205:15793:62044#/2,FCD243JACXX:5:2201:18078:18754#/2 chr1 25403 25740 FCC21NUACXX:5:1216:7574:73145#/1,FCD243JACXX:5:2206:12649:46794#/2,FCC21NUACXX:5:2205:15793:62044#/1,FCD243JACXX:5:2201:18078:18754#/1,FCD243JACXX:5:1112:4148:89702#/2 chr1 25767 25867 FCC21NUACXX:5:1216:7574:73145#/2 chr1 26053 26153 FCD243JACXX:5:1112:4148:89702#/1 chr1 26406 26506 FCC1MK2ACXX:2:2307:2158:37901#/1 chr1 26680 26883 FCC1MK2ACXX:1:2213:6949:42393#/2,FCC1MK2ACXX:1:2315:18190:6749#/1,FCD243JACXX:5:1105:21169:9826#/1,FCC1MK2ACXX:2:2307:2158:37901#/2 chr1 27102 27252 FCC1MK2ACXX:1:2213:6949:42393#/1,FCC1MK2ACXX:1:2315:18190:6749#/2,FCD243JACXX:5:1105:21169:9826#/2 chr1 27582 27785 FCC1MK2ACXX:1:2114:20853:3283#/2,FCC1MK2ACXX:1:1316:3838:11731#/2,FCD243JACXX:5:2201:11248:70268#/1,FCC21NUACXX:5:1202:18034:57963#/1 chr1 27995 28187 FCC1MK2ACXX:1:2114:20853:3283#/1,FCD243JACXX:5:1202:13909:65993#/2,FCC1MK2ACXX:1:1316:3838:11731#/1,FCC1MK2ACXX:1:1111:9873:22822#/1,FCC21NUACXX:5:1202:18034:57963#/2,FCD243JACXX:5:2201:11248:70268#/2 chr1 28198 28298 FCC21NUACXX:5:1303:10255:6040#/1 chr1 28439 28545 FCC1MK2ACXX:1:1111:9873:22822#/2,FCD243JACXX:5:1202:13909:65993#/1 chr1 28577 28674 FCC21NUACXX:5:1303:10255:6040#/2 chr1 28679 28808 FCC1MK2ACXX:1:1106:8013:94636#/2,FCC1MK2ACXX:2:2304:3217:85023#/2 chr1 29089 29191 FCC1MK2ACXX:2:2304:3217:85023#/1,FCC1MK2ACXX:1:1106:8013:94636#/1 chr1 29331 29431 FCC1MK2ACXX:2:2210:9985:83633#/2 chr1 29686 29786 FCC1MK2ACXX:2:2210:9985:83633#/1 chr1 30409 30509 FCC1MK2ACXX:1:1301:14019:75418#/2 chr1 30809 30909 FCC1MK2ACXX:1:1301:14019:75418#/1 chr1 31781 31881 FCC1MK2ACXX:1:1112:12970:36191#/1 chr1 32173 32273 FCC1MK2ACXX:1:1112:12970:36191#/2 chr1 32519 32619 FCD243JACXX:5:1311:16724:97626#/1 chr1 32732 32832 FCD243JACXX:5:1316:15289:11879#/1 chr1 32926 33120 FCD243JACXX:5:1311:16724:97626#/2,FCD243JACXX:5:1313:2205:21712#/2 chr1 33143 33289 FCD243JACXX:5:1316:15289:11879#/2,FCC1MK2ACXX:2:2208:1230:20957#/2 chr1 33449 33669 FCD243JACXX:5:1313:2205:21712#/1,FCD243JACXX:5:1308:6016:8271#/1,FCC1MK2ACXX:2:2208:1230:20957#/1 chr1 33842 33931 FCD243JACXX:5:2105:19228:7972#/2 chr1 33933 34044 FCD243JACXX:5:1308:6016:8271#/2,FCD243JACXX:5:2203:17722:60737#/1 chr1 34070 34162 FCD243JACXX:5:1209:17228:30349#/2 chr1 34268 34451 FCD243JACXX:5:2105:19228:7972#/1,FCD243JACXX:5:2203:17722:60737#/2 chr1 34511 34606 FCD243JACXX:5:1209:17228:30349#/1 chr1 35413 35513 FCC21NUACXX:5:1114:16408:27052#/2 chr1 35792 35892 FCC21NUACXX:5:1114:16408:27052#/1 chr1 36101 36201 FCC1MK2ACXX:1:2208:4266:7960#/1,FCC1MK2ACXX:1:2311:20336:8033#/2 chr1 36528 36625 FCC1MK2ACXX:1:2311:20336:8033#/1,FCC1MK2ACXX:1:2208:4266:7960#/2 chr1 37129 37229 FCC21NUACXX:5:1313:17033:48410#/1 chr1 37516 37616 FCC21NUACXX:5:1313:17033:48410#/2 chr1 37904 37996 FCC1MK2ACXX:2:2205:6549:50320#/1 chr1 38283 38380 FCC1MK2ACXX:2:2205:6549:50320#/2 chr1 38609 38709 FCC1MK2ACXX:2:2210:2576:92182#/1 chr1 38980 39088 FCC1MK2ACXX:2:2210:2576:92182#/2,FCC1MK2ACXX:1:1109:10008:32249#/1 chr1 39099 39199 FCC1MK2ACXX:2:2101:9586:58935#/1 chr1 39418 39585 FCC1MK2ACXX:1:1109:10008:32249#/2,FCC1MK2ACXX:2:2101:9586:58935#/2,FCC1MK2ACXX:1:2107:2708:16186#/1 chr1 39920 40020 FCC1MK2ACXX:1:2107:2708:16186#/2 chr1 43646 43746 FCC1MK2ACXX:1:2210:18159:79187#/1 chr1 43974 44074 FCC1MK2ACXX:1:2206:14818:54615#/2 chr1 44085 44185 FCC1MK2ACXX:1:2210:18159:79187#/2 chr1 44304 44504 FCC1MK2ACXX:2:1111:10402:8042#/1,FCC1MK2ACXX:1:2206:14818:54615#/1 chr1 44688 44788 FCC1MK2ACXX:2:1111:10402:8042#/2 chr1 45372 45472 FCC21NUACXX:5:1213:14336:15983#/2 chr1 45738 45867 FCC21NUACXX:5:1213:14336:15983#/1,FCC21NUACXX:5:2111:4349:47495#/2,FCC21NUACXX:5:2310:9277:44573#/1 chr1 46111 46212 FCC21NUACXX:5:2111:4349:47495#/1,FCC21NUACXX:5:2310:9277:44573#/2 chr1 47250 47346 FCD243JACXX:5:1109:13398:97939#/1 chr1 47593 47693 FCD243JACXX:5:1109:13398:97939#/2 chr1 47820 47920 FCC1MK2ACXX:2:1315:1607:59533#/1 chr1 48088 48193 FCC1MK2ACXX:2:1315:1607:59533#/2,FCC21NUACXX:5:2202:18282:16519#/1 chr1 48445 48677 FCD243JACXX:5:1102:1566:2621#/2,FCC21NUACXX:5:2202:18282:16519#/2,FCC1MK2ACXX:1:2313:6915:61276#/1 chr1 48681 48781 FCC21NUACXX:5:2110:14255:7805#/1 chr1 48832 48932 FCD243JACXX:5:1102:1566:2621#/1 chr1 48967 49067 FCC1MK2ACXX:1:2313:6915:61276#/2 chr1 49092 49192 FCC21NUACXX:5:2110:14255:7805#/2 chr1 5333587 5344172 line1 0 - 5334680 5344172 chr1 5481008 5484749 line2 0 - 5481796 5484749 chr1 5481008 5484749 line3 0 - 5481796 5484749 chr1 5481008 5484749 line4 0 - 5481796 5484749 chr1 6763278 6766882 line5 0 - 7766544 6766882 chr1 10003 10143 10024.5 chr1 10358 10428 10358 chr1 11780 11921 11800.5 chr1 11996 12101 11998.5 chr1 12136 12347 12213.25 chr1 12400 12503 12401.5 chr1 12635 12779 12661 chr1 12819 12919 12819 chr1 13039 13139 13039 chr1 13165 13287 13176 chr1 13561 13731 13595 chr1 14025 14125 14025 chr1 14221 14340 14230.5 chr1 14440 14715 14553.66667 chr1 14805 15172 14944.71429 chr1 15250 15350 15250 chr1 15470 15603 15486.5 chr1 15924 16065 15944.5 chr1 16155 16255 16155 chr1 16314 16438 16326 chr1 16561 16661 16561 chr1 16945 17038 16945 chr1 17372 17472 17372 chr1 17525 17625 17525 chr1 17634 17734 17634 chr1 17908 18008 17908 chr1 18033 18133 18033 chr1 18152 18252 18152 chr1 18264 18364 18264 chr1 18577 18742 18610 chr1 19658 19758 19658 chr1 19819 19966 19842.5 chr1 20059 20320 20143.33333 chr1 20457 20627 20494 chr1 20641 20741 20641 chr1 20754 20854 20754 chr1 21047 21139 21047 chr1 21177 21277 21177 chr1 21449 21549 21449 chr1 21834 22029 21876 chr1 22061 22149 22061 chr1 22242 22448 22297.8 chr1 22512 22566 22512 chr1 22748 22848 22748 chr1 22870 22970 22870 chr1 23130 23228 23130 chr1 23250 23350 23250 chr1 23557 23615 23557 chr1 24000 24120 24010 chr1 24248 24612 24351.66667 chr1 24683 24850 24711 chr1 24921 25011 24921 chr1 25055 25291 25128.5 chr1 25403 25740 25542.8 chr1 25767 25867 25767 chr1 26053 26153 26053 chr1 26406 26506 26406 chr1 26680 26883 26730.5 chr1 27102 27252 27125 chr1 27582 27785 27637 chr1 27995 28187 28038 chr1 28198 28298 28198 chr1 28439 28545 28442 chr1 28577 28674 28577 chr1 28679 28808 28693.5 chr1 29089 29191 29090 chr1 29331 29431 29331 chr1 29686 29786 29686 chr1 30409 30509 30409 chr1 30809 30909 30809 chr1 31781 31881 31781 chr1 32173 32273 32173 chr1 32519 32619 32519 chr1 32732 32832 32732 chr1 32926 33120 32973 chr1 33143 33289 33189.5 chr1 33449 33669 33502.33333 chr1 33842 33931 33842 chr1 33933 34044 33938.5 chr1 34070 34162 34070 chr1 34268 34451 34309.5 chr1 34511 34606 34511 chr1 35413 35513 35413 chr1 35792 35892 35792 chr1 36101 36201 36101.5 chr1 36528 36625 36530.5 chr1 37129 37229 37129 chr1 37516 37616 37516 chr1 37904 37996 37904 chr1 38283 38380 38283 chr1 38609 38709 38609 chr1 38980 39088 38984 chr1 39099 39199 39099 chr1 39418 39585 39478 chr1 39920 40020 39920 chr1 43646 43746 43646 chr1 43974 44074 43974 chr1 44085 44185 44085 chr1 44304 44504 44354 chr1 44688 44788 44688 chr1 45372 45472 45372 chr1 45738 45867 45750.33333 chr1 46111 46212 46111.5 chr1 47250 47346 47250 chr1 47593 47693 47593 chr1 47820 47920 47820 chr1 48088 48193 48090.5 chr1 48445 48677 48500 chr1 48681 48781 48681 chr1 48832 48932 48832 chr1 48967 49067 48967 chr1 49092 49192 49092 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ONɖqm2^61>53rr`9l9~kˁrr`9l9X[,-Öiˉ-'Ӗiˉrrb9m9XN[N,˖eٲ~k²lYX- ˲eaY,,˖eٲ,[mƲmٿecٶl,ۖe۲l[6mƲmX-e˅-˖ e˅rral\\X.[.,-7ۖXn[n,-7ۖmˍrrcm<[> Nɖqm2^61>533hudlI3 kKwY[> ڒ]g@~}|%΀-iudmI3 kKwnKwY[> ڒ]g@֖:}|lI3 kKwY[> ڒ]g@֖:G–:}|%΀-iudmI3 mI3 kKwY[> ڒ]g@֖:˖:}|%΀-iudmI3 _mI3 kKwY[> ڒ]g@֖:upy3 kKwY[> ڒ]g@֖:,<|Ɠ-b۸emc|k|gۇwY[> ڒ]g@֖:}|v%΀-iudmI3 kKwY[> Hْ]g@֖:}|%΀-iu,mI3 kKwY[> ڒ]g@֖:ʶ}|%΀-iudmI3 kKw~[> ڒ]g@֖:}|%΀o>u ڒ]g@֖:}|%΀o>u ڒ]g@֖:}|%΀o>u ڒ]g@֖:}|%΀|,K:udd˸6nv/vo_c]g@֖:}|%΀-iu'}|%΀-iudmI3 kKw-iudmI3 kKwY[> ڒ]g@~dKwY[> ڒ]g@֖:}|ْ]g@֖:}|%΀-iu䧁}|%΀-iudmI3 kKwߺ}<|%΀-iudmI3 kKwߺ}<|%΀-iudmI3 kKwߺ}<|%΀-iudmI3 kKwI,<|Ɠ-b۸emc|k|gۇwY[> ڒ]g@֖:}|9lI3 kKwY[> ڒ]g@֖:-iudmI3 kKwY[> ڒ]g@^%΀-iudmI3 kKwY[> ȋj}|%΀-iudmI3 kKwyЖ:}|%΀-iudmI3[w:}|%΀-iudmI3[w:}|%΀-iudmI3[w:}|%΀-iudmI3 ˒wi<2.]Ƌƛ=ƇƗ}X}<|%΀-iudmI3 kKwy-iudmI3 kKwY[> ڒ]g@aKwY[> ڒ]g@֖:}|ؒ]g@֖:}|%΀-iu6}|%΀-iudmI3 kKwy-iudmI3 kKwY[> ڒ]gn:udmI3 kKwY[> ڒ]gn:udmI3 kKwY[> ڒ]gn:udmI3 kKwY[> ڒ]g@u'K:udd˸6nv/vo_c]g@֖:}|%΀-iu=}|%΀-iudmI3 kKwy-iudmI3 kKwY[> ڒ]g@ޱjKwY[> 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c}ΉGO]]]]]xu>Ήѕ}Ήѕ}Ήѕ}Ήѕ}ΉGO]]]]]xu>Ήѕ}Ήѕ}Ήѕ}Ήѕ}ΉGO]]]]]xu>Ήѕ}Ήѕ}Ήѕ}Ήѕ}ΉGO]]]]]뜸?S_[?W[|v+>v+>v+>v+>v~g91c91c91c91c9|v+>v+>v+>v+>v~g91c91c91c91c9|v+>v+>v+>v+>v~g91c91c91c91c9|v+>v+>v+>v+>v~g91c91c91c91c9|v+>v+>v+>v+>vwv#~?+~?'_u+>uϮsbteǮsbteǮsbteǮsbteǮsS:'FW}:'FW}:'FW}:'FW}:'>uϮsbteǮsbteǮsbteǮsbteǮsS:'FW}:'FW}:'FW}:'FW}:'>uϮsbteǮsbteǮsbteǮsbteǮsS:'FW}:'FW}:'FW}:'FW}:'>uϮsbteǮsbteǮsbteǮsbteǮsS:'FW}:'FW}:'FW}:'FW}:'>uϮsbteǮsbteǮsbteǮsbteǮsήsbPOgRowS_Q_onߧuNuNuNuNuN<}:]ʾ]ʾ]ʾ]ʾ]ģߧuNuNuNuNuN<}:]ʾ]ʾ]ʾ]ʾ]ģߧuNuNuN>}s~>}s~?)%Xchr1 10 20 chr1 30 40 chr1 40 50 chr1 45 100 chr1 10003 10143 chr1,chr1 chr1 10358 10428 chr1 chr1 11780 11921 chr1,chr1 chr1 11996 12101 chr1,chr1 chr1 12136 12347 chr1,chr1,chr1,chr1 chr1 12400 12503 chr1,chr1 chr1 12635 12779 chr1,chr1,chr1 chr1 12819 12919 chr1 chr1 13039 13139 chr1 chr1 13165 13287 chr1,chr1 chr1 13561 13731 chr1,chr1 chr1 14025 14125 chr1 chr1 14221 14340 chr1,chr1 chr1 14440 14715 chr1,chr1,chr1,chr1,chr1,chr1 chr1 14805 15172 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38980 39088 chr1,chr1 chr1 39099 39199 chr1 chr1 39418 39585 chr1,chr1,chr1 chr1 39920 40020 chr1 chr1 43646 43746 chr1 chr1 43974 44074 chr1 chr1 44085 44185 chr1 chr1 44304 44504 chr1,chr1 chr1 44688 44788 chr1 chr1 45372 45472 chr1 chr1 45738 45867 chr1,chr1,chr1 chr1 46111 46212 chr1,chr1 chr1 47250 47346 chr1 chr1 47593 47693 chr1 chr1 47820 47920 chr1 chr1 48088 48193 chr1,chr1 chr1 48445 48677 chr1,chr1,chr1 chr1 48681 48781 chr1 chr1 48832 48932 chr1 chr1 48967 49067 chr1 chr1 49092 49192 chr1 chr1 10 20 a1 1 + chr1 30 40 a2 2 + chr1 40 50 a3 3 - chr1 45 100 a4 4 + chr2 10 20 a1 5 + chr2 30 40 a2 6 + chr2 42 50 a3 7 + chr2 45 100 a4 8 - BCY[hUښR-(^JsD iES˺ɦcs QEV BIEҾ>JXϒ=̜c9̙/icehk_*MLw߶ec߆7n3SoPh͋ܯ=4谒;{W}#c{ye`_h=[zBuFgz&jk1:*l ͌i FARki$O1 U{cd}jg2*hI:$IH<;HĬT^+F4$%^ 3ՙ ǹׂgf# ]Mb8""L0iQUTݷPuTnv8ct((1kʸ{{dBS@y ms8"75%TyTfB!P2O~RJrM'HuȐHORr\lqVĄ5.҂tbKII0кp&RWz|YZϴHĐJ'i}xp^;f=I/ )@7hgL޾@XX!BJĊpYEcEhGqHk3Jv2J \;4?zI"X(YoX7';/rj‹:q]ʯ9\ޣ]oms_Gm[ms*Oop|V:/u;ykggZW+Lw%O(-{߮*@%\v˳Zi Y1,U/:Q-&wk)?j +ɮU-!OlDǙ-mmJ;69QqDD2n^[hP ?O`~Ζen/&fK'&7$Zr8pl= Th?SI>Jy_C?q1 6eDmanQ;xpQ{h^u氢,"~>,~5pB_;jw=|6 }Qs{Q ED-a}D`W"j k0l#ՊkZ@9%amDÈZÚ@ADma38a º=d*X -uS5A4t"czub:o*3=CU0]^2v_מT#)Ӷȶ|wb&BCchr1 10 20 a1 chr1 30 40 a2 chr1 40 50 a3 chr1 45 100 a4 ##fileformat=VCFv4.1 ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##FORMAT= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##INFO= ##UnifiedGenotyper="analysis_type=UnifiedGenotyper input_file=[bam/all.conc.on.pos.dedup.realigned.bam] read_buffer_size=null phone_home=STANDARD read_filter=[] intervals=null excludeIntervals=null interval_set_rule=UNION interval_merging=ALL reference_sequence=/home/arq5x/cphg-home/shared/genomes/hg19/bwa/gatk/hg19_gatk.fa rodBind=[] nonDeterministicRandomSeed=false downsampling_type=BY_SAMPLE downsample_to_fraction=null downsample_to_coverage=250 baq=OFF baqGapOpenPenalty=40.0 performanceLog=null useOriginalQualities=false defaultBaseQualities=-1 validation_strictness=SILENT unsafe=null num_threads=10 num_cpu_threads=null num_io_threads=null num_bam_file_handles=null read_group_black_list=null pedigree=[] pedigreeString=[] pedigreeValidationType=STRICT allow_intervals_with_unindexed_bam=false logging_level=INFO log_to_file=null help=false genotype_likelihoods_model=BOTH p_nonref_model=EXACT heterozygosity=0.0010 pcr_error_rate=1.0E-4 genotyping_mode=DISCOVERY output_mode=EMIT_VARIANTS_ONLY standard_min_confidence_threshold_for_calling=30.0 standard_min_confidence_threshold_for_emitting=30.0 computeSLOD=false alleles=(RodBinding name= source=UNBOUND) min_base_quality_score=17 max_deletion_fraction=0.05 multiallelic=false max_alternate_alleles=5 min_indel_count_for_genotyping=5 indel_heterozygosity=1.25E-4 indelGapContinuationPenalty=10.0 indelGapOpenPenalty=45.0 indelHaplotypeSize=80 bandedIndel=false indelDebug=false ignoreSNPAlleles=false dbsnp=(RodBinding name= source=UNBOUND) out=org.broadinstitute.sting.gatk.io.stubs.VCFWriterStub NO_HEADER=org.broadinstitute.sting.gatk.io.stubs.VCFWriterStub sites_only=org.broadinstitute.sting.gatk.io.stubs.VCFWriterStub debug_file=null metrics_file=null annotation=[] excludeAnnotation=[] filter_mismatching_base_and_quals=false" ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##contig= ##reference=file:///home/arq5x/cphg-home/shared/genomes/hg19/bwa/gatk/hg19_gatk.fa ##SnpEffVersion="SnpEff 3.0g (build 2012-08-31), by Pablo Cingolani" ##SnpEffCmd="SnpEff -i vcf -o vcf GRCh37.66 /home/udp3f/cphg-home/projects/rs-exome/varCalling/2012-Feb-01/all.raw.nobaq.vcf " ##INFO= #CHROM POS ID REF ALT QUAL FILTER INFO FORMAT 1094PC0005 1094PC0009 1094PC0012 1094PC0013 chr1 30860 . G C 33.46 . AC=2;AF=0.053;AN=38;BaseQRankSum=2.327;DP=49;Dels=0.00;FS=3.128;HRun=0;HaplotypeScore=0.6718;InbreedingCoeff=0.1005;MQ=36.55;MQ0=0;MQRankSum=0.217;QD=16.73;ReadPosRankSum=2.017;EFF=DOWNSTREAM(MODIFIER||||85|FAM138A|protein_coding|CODING|ENST00000417324|),DOWNSTREAM(MODIFIER|||||FAM138A|processed_transcript|CODING|ENST00000461467|),DOWNSTREAM(MODIFIER|||||MIR1302-10|miRNA|NON_CODING|ENST00000408384|),INTRON(MODIFIER|||||MIR1302-10|antisense|NON_CODING|ENST00000469289|),INTRON(MODIFIER|||||MIR1302-10|antisense|NON_CODING|ENST00000473358|),UPSTREAM(MODIFIER|||||WASH7P|unprocessed_pseudogene|NON_CODING|ENST00000423562|),UPSTREAM(MODIFIER|||||WASH7P|unprocessed_pseudogene|NON_CODING|ENST00000430492|),UPSTREAM(MODIFIER|||||WASH7P|unprocessed_pseudogene|NON_CODING|ENST00000438504|),UPSTREAM(MODIFIER|||||WASH7P|unprocessed_pseudogene|NON_CODING|ENST00000488147|),UPSTREAM(MODIFIER|||||WASH7P|unprocessed_pseudogene|NON_CODING|ENST00000538476|) GT:AD:DP:GQ:PL 0/0:7,0:7:15.04:0,15,177 0/0:2,0:2:3.01:0,3,39 0/0:6,0:6:12.02:0,12,143 0/0:4,0:4:9.03:0,9,119 chr1 69270 . A G 2694.18 . AC=40;AF=1.000;AN=40;DP=83;Dels=0.00;FS=0.000;HRun=0;HaplotypeScore=0.0000;InbreedingCoeff=-0.0598;MQ=31.06;MQ0=0;QD=32.86;EFF=SYNONYMOUS_CODING(LOW|SILENT|tcA/tcG|S60|305|OR4F5|protein_coding|CODING|ENST00000335137|exon_1_69091_70008) GT:AD:DP:GQ:PL ./. ./. 1/1:0,3:3:9.03:106,9,0 1/1:0,6:6:18.05:203,18,0 chr1 69511 . A G 77777.27 . AC=49;AF=0.875;AN=56;BaseQRankSum=0.150;DP=2816;DS;Dels=0.00;FS=21.286;HRun=0;HaplotypeScore=3.8956;InbreedingCoeff=0.0604;MQ=32.32;MQ0=0;MQRankSum=1.653;QD=27.68;ReadPosRankSum=2.261;EFF=NON_SYNONYMOUS_CODING(MODERATE|MISSENSE|Aca/Gca|T141A|305|OR4F5|protein_coding|CODING|ENST00000335137|exon_1_69091_70008) GT:AD:DP:GQ:PL ./. ./. 0/1:2,4:6:15.70:16,0,40 0/1:2,2:4:21.59:22,0,40 chr1 874816 . C CT 1208.91 . AC=8;AF=0.105;AN=76;BaseQRankSum=-1.391;DP=785;FS=0.000;HRun=1;HaplotypeScore=68.5485;InbreedingCoeff=0.1619;MQ=57.70;MQ0=0;MQRankSum=-0.585;QD=13.14;ReadPosRankSum=-2.428;EFF=DOWNSTREAM(MODIFIER||||108|SAMD11|protein_coding|CODING|ENST00000437963|),DOWNSTREAM(MODIFIER||||178|SAMD11|protein_coding|CODING|ENST00000420190|),DOWNSTREAM(MODIFIER||||749|NOC2L|protein_coding|CODING|ENST00000327044|),DOWNSTREAM(MODIFIER|||||NOC2L|processed_transcript|CODING|ENST00000477976|),DOWNSTREAM(MODIFIER|||||NOC2L|processed_transcript|CODING|ENST00000483767|),FRAME_SHIFT(HIGH||-/T|-228?|681|SAMD11|protein_coding|CODING|ENST00000342066|exon_1_874655_874840),UPSTREAM(MODIFIER|||||SAMD11|processed_transcript|CODING|ENST00000474461|),UPSTREAM(MODIFIER|||||SAMD11|processed_transcript|CODING|ENST00000478729|),UPSTREAM(MODIFIER|||||SAMD11|retained_intron|CODING|ENST00000464948|),UPSTREAM(MODIFIER|||||SAMD11|retained_intron|CODING|ENST00000466827|) GT:AD:DP:GQ:PL 0/0:7,0:7:18.06:0,18,252 0/0:16,0:16:45.15:0,45,630 0/0:15,0:15:39.10:0,39,503 0/0:13,0:13:33.11:0,33,462 chr1 879676 . G A 6715.87 . AC=63;AF=0.955;AN=66;BaseQRankSum=-0.665;DP=201;Dels=0.00;FS=0.000;HRun=3;HaplotypeScore=0.1046;InbreedingCoeff=-0.1218;MQ=56.71;MQ0=0;MQRankSum=-2.066;QD=33.41;ReadPosRankSum=-1.877;EFF=DOWNSTREAM(MODIFIER|||||NOC2L|processed_transcript|CODING|ENST00000496938|),DOWNSTREAM(MODIFIER|||||SAMD11|processed_transcript|CODING|ENST00000474461|),DOWNSTREAM(MODIFIER|||||SAMD11|processed_transcript|CODING|ENST00000478729|),DOWNSTREAM(MODIFIER|||||SAMD11|retained_intron|CODING|ENST00000464948|),DOWNSTREAM(MODIFIER|||||SAMD11|retained_intron|CODING|ENST00000466827|),EXON(MODIFIER|||||NOC2L|processed_transcript|CODING|ENST00000477976|),EXON(MODIFIER|||||NOC2L|processed_transcript|CODING|ENST00000483767|),UTR_3_PRIME(MODIFIER||||681|SAMD11|protein_coding|CODING|ENST00000342066|),UTR_3_PRIME(MODIFIER||||749|NOC2L|protein_coding|CODING|ENST00000327044|) GT:AD:DP:GQ:PL 1/1:0,6:7:18.05:218,18,0 1/1:0,7:7:21.05:262,21,0 1/1:0,8:8:24.07:308,24,0 1/1:0,5:5:15.05:187,15,0 chr1 935492 . G T 41.57 . AC=4;AF=0.67;AN=6;BaseQRankSum=0.736;DP=3;Dels=0.00;FS=0.000;HRun=3;HaplotypeScore=0.0000;MQ=60.00;MQ0=0;MQRankSum=-0.736;QD=20.79;ReadPosRankSum=-0.736;EFF=START_GAINED(LOW||||247|HES4|protein_coding|CODING|ENST00000428771|exon_1_935072_935552),UPSTREAM(MODIFIER||||189|HES4|protein_coding|CODING|ENST00000484667|),UPSTREAM(MODIFIER||||221|HES4|protein_coding|CODING|ENST00000304952|),UPSTREAM(MODIFIER|||||HES4|processed_transcript|CODING|ENST00000481869|) GT:AD:DP:GQ:PL ./. ./. 1/1:0,1:1:3.01:39,3,0 ./. chr1 1334052 . CTAGAG C 5078.01 . AC=3;AF=0.039;AN=76;BaseQRankSum=12.748;DP=4561;DS;FS=8.748;HRun=0;HaplotypeScore=609.0108;InbreedingCoeff=-0.0411;MQ=59.18;MQ0=0;MQRankSum=-15.062;QD=20.31;ReadPosRankSum=-1.131;EFF=DOWNSTREAM(MODIFIER||||149|MRPL20|protein_coding|CODING|ENST00000344843|),DOWNSTREAM(MODIFIER|||||MRPL20|processed_transcript|CODING|ENST00000487659|),DOWNSTREAM(MODIFIER|||||MRPL20|processed_transcript|CODING|ENST00000492508|),DOWNSTREAM(MODIFIER|||||MRPL20|processed_transcript|CODING|ENST00000493287|),DOWNSTREAM(MODIFIER|||||RP4-758J18.5.1|processed_transcript|NON_CODING|ENST00000514958|),EXON(MODIFIER|||||CCNL2|processed_transcript|CODING|ENST00000497013|),INTRON(MODIFIER||||226|CCNL2|protein_coding|CODING|ENST00000408918|),INTRON(MODIFIER||||520|CCNL2|protein_coding|CODING|ENST00000400809|),INTRON(MODIFIER|||||CCNL2|nonsense_mediated_decay|CODING|ENST00000425598|),INTRON(MODIFIER|||||CCNL2|nonsense_mediated_decay|CODING|ENST00000481223|),INTRON(MODIFIER|||||CCNL2|nonsense_mediated_decay|CODING|ENST00000488340|),INTRON(MODIFIER|||||CCNL2|nonsense_mediated_decay|CODING|ENST00000496007|),SPLICE_SITE_ACCEPTOR(HIGH|||||CCNL2|nonsense_mediated_decay|CODING|ENST00000488340|),UPSTREAM(MODIFIER|||||CCNL2|processed_transcript|CODING|ENST00000463895|),UPSTREAM(MODIFIER|||||CCNL2|processed_transcript|CODING|ENST00000471930|),UPSTREAM(MODIFIER|||||CCNL2|processed_transcript|CODING|ENST00000482621|),UPSTREAM(MODIFIER|||||CCNL2|retained_intron|CODING|ENST00000473872|),UPSTREAM(MODIFIER|||||RP4-758J18.2.1|processed_transcript|NON_CODING|ENST00000418833|),UPSTREAM(MODIFIER|||||RP4-758J18.2.1|processed_transcript|NON_CODING|ENST00000444362|),UPSTREAM(MODIFIER|||||RP4-758J18.2.1|processed_transcript|NON_CODING|ENST00000447725|),UPSTREAM(MODIFIER|||||RP4-758J18.2.1|processed_transcript|NON_CODING|ENST00000448629|),UPSTREAM(MODIFIER|||||RP4-758J18.3.1|processed_transcript|NON_CODING|ENST00000453521|) GT:AD:DP:GQ:PL 0/0:116,0:116:99:0,310,8807 0/0:106,0:106:99:0,275,7825 0/1:59,38:97:99:2157,0,3681 0/1:61,38:99:99:2174,0,3121 chr1 31896608 . C T 1690.17 . AC=3;AF=0.039;AN=76;BaseQRankSum=-1.970;DP=1774;Dels=0.00;FS=1.532;HRun=0;HaplotypeScore=2.0440;InbreedingCoeff=-0.0492;MQ=58.72;MQ0=0;MQRankSum=0.940;QD=12.25;ReadPosRankSum=0.534;EFF=EXON(MODIFIER|||||SERINC2|processed_transcript|CODING|ENST00000487207|),EXON(MODIFIER|||||SERINC2|processed_transcript|CODING|ENST00000491976|),SYNONYMOUS_CODING(LOW|SILENT|acC/acT|T36|455|SERINC2|protein_coding|CODING|ENST00000373709|exon_1_31896540_31896701),SYNONYMOUS_CODING(LOW|SILENT|acC/acT|T40|459|SERINC2|protein_coding|CODING|ENST00000536384|exon_1_31896540_31896701),SYNONYMOUS_CODING(LOW|SILENT|acC/acT|T40|459|SERINC2|protein_coding|CODING|ENST00000536859|exon_1_31896540_31896701),SYNONYMOUS_CODING(LOW|SILENT|acC/acT|T45|464|SERINC2|protein_coding|CODING|ENST00000373710|exon_1_31896540_31896701) GT:AD:DP:GQ:PL 0/0:3,0:3:3.01:0,3,36 0/0:3,0:3:6.02:0,6,75 0/0:10,0:10:24.06:0,24,282 0/0:5,0:5:15.04:0,15,181 ##fileformat=VCFv4.1 19 252806 791255 G 70.90 . TOOL=LUMPY;SVTYPE=DEL;SVLEN=-389,-4611;END=253195;STR=+-:4;IMPRECISE;CIPOS=-2,137;CIEND=0,0;EVENT=791255;SUP=4;PESUP=4;SRSUP=0;EV=PE;PRIN;CSQ=intergenic_variant|||||||||| 19 260365 791256 C 33.71 . TOOL=LUMPY;SVTYPE=DEL;SVLEN=-680;END=261045;STR=+-:4;IMPRECISE;CIPOS=-1,257;CIEND=0,0;EVENT=791256;SUP=4;PESUP=4;SRSUP=0;EV=PE;PRIN;CSQ=upstream_gene_variant|||ENSG00000271846|CTD-3113P16.9|ENST00000607399|||||processed_pseudogene 19 265134 791257 A 20.25 . TOOL=LUMPY;SVTYPE=DEL;SVLEN=-558;END=265692;STR=+-:4;IMPRECISE;CIPOS=-1,196;CIEND=0,0;EVENT=791257;SUP=4;PESUP=4;SRSUP=0;EV=PE;PRIN;CSQ=intergenic_variant|||||||||| 19 265986 791258 A 22.15 . TOOL=LUMPY;SVTYPE=DEL;SVLEN=-401;END=266387;STR=+-:6;IMPRECISE;CIPOS=-2,87;CIEND=0,0;EVENT=791258;SUP=6;PESUP=6;SRSUP=0;EV=PE;PRIN;CSQ=intergenic_variant|||||||||| chr1 10003 10143 0 chr1 10358 10428 0 chr1 11780 11921 488.5 chr1 11996 12101 503 chr1 12136 12347 1 chr1 12400 12503 -503 chr1 12635 12779 -174.3333333 chr1 12819 12919 468 chr1 13039 13139 -458 chr1 13165 13287 14 chr1 13561 13731 0 chr1 14025 14125 -496 chr1 14221 14340 474 chr1 14440 14715 164 chr1 14805 15172 -54.71428571 chr1 15250 15350 -513 chr1 15470 15603 -518 chr1 15924 16065 481.5 chr1 16155 16255 506 chr1 16314 16438 -481.5 chr1 16561 16661 -506 chr1 16945 17038 527 chr1 17372 17472 -527 chr1 17525 17625 483 chr1 17634 17734 499 chr1 17908 18008 -483 chr1 18033 18133 -499 chr1 18152 18252 525 chr1 18264 18364 478 chr1 18577 18742 -501.5 chr1 19658 19758 501 chr1 19819 19966 477.5 chr1 20059 20320 -6.833333333 chr1 20457 20627 -471.6666667 chr1 20641 20741 498 chr1 20754 20854 523 chr1 21047 21139 -498 chr1 21177 21277 -523 chr1 21449 21549 475 chr1 21834 22029 262.5 chr1 22061 22149 505 chr1 22242 22448 -305 chr1 22512 22566 -505 chr1 22748 22848 480 chr1 22870 22970 480 chr1 23130 23228 -480 chr1 23250 23350 -480 chr1 23557 23615 503 chr1 24000 24120 -1 chr1 24248 24612 173.1666667 chr1 24683 24850 -191.3333333 chr1 24921 25011 -499 chr1 25055 25291 261.25 chr1 25403 25740 -107 chr1 25767 25867 -464 chr1 26053 26153 -513 chr1 26406 26506 477 chr1 26680 26883 266.75 chr1 27102 27252 -514.6666667 chr1 27582 27785 503.75 chr1 27995 28187 -166.3333333 chr1 28198 28298 476 chr1 28439 28545 -508.5 chr1 28577 28674 -476 chr1 28679 28808 496.5 chr1 29089 29191 -496.5 chr1 29331 29431 455 chr1 29686 29786 -455 chr1 30409 30509 500 chr1 30809 30909 -500 chr1 31781 31881 492 chr1 32173 32273 -492 chr1 32519 32619 507 chr1 32732 32832 511 chr1 32926 33120 3 chr1 33143 33289 -39 chr1 33449 33669 -135.3333333 chr1 33842 33931 526 chr1 33933 34044 -16.5 chr1 34070 34162 536 chr1 34268 34451 -516.5 chr1 34511 34606 -536 chr1 35413 35513 479 chr1 35792 35892 -479 chr1 36101 36201 519.5 chr1 36528 36625 -519.5 chr1 37129 37229 487 chr1 37516 37616 -487 chr1 37904 37996 476 chr1 38283 38380 -476 chr1 38609 38709 471 chr1 38980 39088 29 chr1 39099 39199 485 chr1 39418 39585 -174 chr1 39920 40020 -492 chr1 43646 43746 539 chr1 43974 44074 530 chr1 44085 44185 -539 chr1 44304 44504 -23 chr1 44688 44788 -484 chr1 45372 45472 466 chr1 45738 45867 148 chr1 46111 46212 -455 chr1 47250 47346 443 chr1 47593 47693 -443 chr1 47820 47920 368 chr1 48088 48193 58.5 chr1 48445 48677 164 chr1 48681 48781 511 chr1 48832 48932 -487 chr1 48967 49067 -490 chr1 49092 49192 -511 set -e; BT=${BT-../../bin/bedtools} FAILURES=0; check() { if diff $1 $2; then echo ok else FAILURES=$(expr $FAILURES + 1); echo fail fi } # cat a.bed # chr1 10 20 # chr1 30 40 # chr1 40 50 # chr1 45 100 ########################################################### # Test a basic merge; one interval should be un-merged, # the other two should be merged. ########################################################### echo -e " merge.t1...\c" echo \ "chr1 10 20 chr1 30 100" > exp $BT merge -i a.bed > obs check obs exp rm obs exp ########################################################### # Test that -n option is shown as deperecated ########################################################### echo -e " merge.t2...\c" echo "***** ERROR: -n option is deprecated. Please see the documentation for the -c and -o column operation options. *****" > exp $BT merge -i a.bed -n 2>&1 > /dev/null | tail -1 > obs check obs exp rm obs exp ########################################################### # Test the counting of merged intervals. (-n) ########################################################### echo -e " merge.t3...\c" echo \ "chr1 10 20 1 chr1 30 100 3" > exp $BT merge -i a.bed -c 1 -o count > obs check obs exp rm obs exp ########################################################### # Test that -nms option is deprecated ########################################################### echo -e " merge.t4...\c" echo "***** ERROR: -nms option is deprecated. Please see the documentation for the -c and -o column operation options. *****" > exp $BT merge -i a.bed -nms 2>&1 > /dev/null | tail -1 > obs check obs exp rm obs exp ########################################################### # Test the listing of names from merged intervals. ########################################################### echo -e " merge.t5...\c" echo \ "chr1 10 20 a1 chr1 30 100 a2,a3,a4" > exp $BT merge -i a.names.bed -c 4 -o collapse > obs check obs exp rm obs exp ########################################################### # collapsed list of the names, and sum of the scores ########################################################### echo -e " merge.t6...\c" echo \ "chr1 10 20 a1 1 chr1 30 100 a2,a3,a4 9 chr2 10 20 a1 5 chr2 30 40 a2 6 chr2 42 100 a3,a4 15" > exp $BT merge -i a.full.bed -c 4,5 -o collapse,sum > obs check obs exp rm obs exp ########################################################### # count intervals and sum of scores ########################################################### echo -e " merge.t7...\c" echo \ "chr1 10 20 1 1 chr1 30 100 3 9 chr2 10 20 1 5 chr2 30 40 1 6 chr2 42 100 2 15" > exp $BT merge -i a.full.bed -c 5 -o count,sum> obs check obs exp rm obs exp ########################################################### # count, collapsed names, and sum of scores ########################################################### echo -e " merge.t8...\c" echo \ "chr1 10 20 a1 1 1 chr1 30 100 a2,a3,a4 9 3 chr2 10 20 a1 5 1 chr2 30 40 a2 6 1 chr2 42 100 a3,a4 15 2" > exp $BT merge -i a.full.bed -c 4,5,4 -o collapse,sum,count > obs check obs exp rm obs exp ########################################################### # stranded merge, show sign, collapsed names, sum of # scores, and count ########################################################### echo -e " merge.t9a...\c" echo \ "chr1 10 20 a1 1 1 chr1 30 40 a2 2 1 chr1 40 50 a3 3 1 chr1 45 100 a4 4 1 chr2 10 20 a1 5 1 chr2 30 40 a2 6 1 chr2 42 50 a3 7 1 chr2 45 100 a4 8 1" > exp $BT merge -i a.full.bed -s -c 4,5,6 -o collapse,sum,count > obs check obs exp rm obs exp ########################################################### # stranded merge, show sign, collapsed names, sum of # scores, and count ########################################################### echo -e " merge.t9b...\c" echo \ "chr1 10 20 a1 1 + chr1 30 40 a2 2 + chr1 40 50 a3 3 - chr1 45 100 a4 4 + chr2 10 20 a1 5 + chr2 30 40 a2 6 + chr2 42 50 a3 7 + chr2 45 100 a4 8 -" > exp $BT merge -i a.full.bed -s -c 4,5,6 -o collapse,sum,collapse > obs check obs exp rm obs exp ########################################################### # Test the use of a custom delimiter for -delim option ########################################################### echo -e " merge.t10...\c" echo \ "chr1 10 20 a1 chr1 30 100 a2|a3|a4" > exp $BT merge -i a.names.bed -delim "|" -c 4 -o collapse > obs check obs exp rm obs exp ########################################################### # Test that stranded merge not allowed with VCF ########################################################### VCF_FILE=testA.vcf echo -e " merge.t11...\c" echo "***** ERROR: stranded merge not supported for VCF file $VCF_FILE. *****" >exp $BT merge -i $VCF_FILE -s 2>&1 > /dev/null | tail -1 > obs check exp obs rm obs exp ########################################################### # Test that column ops not allowed with BAM if col greater # than 11. # # EDIT: This test has been moved to test #35, after the # other bam column tests. ########################################################### echo -e " merge.t12...\c" #echo "***** ERROR: Requested column 12, but database file fullFields.bam only has fields 1 - 11." > exp #$BT merge -i fullFields.bam -c 12 -o sum 2>&1 > /dev/null | head -3 | tail -1 > obs #check exp obs #rm obs exp echo ok ########################################################### # Test that VCF input gives BED3 output ########################################################### echo -e " merge.t13...\c" echo \ "chr1 30859 30860 chr1 69269 69270 chr1 69510 69511 chr1 874815 874816 chr1 879675 879676 chr1 935491 935492 chr1 1334051 1334057 chr1 31896607 31896608" > exp $BT merge -i testA.vcf > obs check exp obs rm obs exp ########################################################### # Test that GFF input gives BED3 output ########################################################### echo -e " merge.t14...\c" echo \ "chr22 9999999 10001000 chr22 10009999 10010100 chr22 10019999 10025000" > exp $BT merge -i a.gff > obs check exp obs rm obs exp ########################################################### # Test that stranded merge where some records have # unknown strand works correctly ########################################################### echo -e " merge.t15...\c" echo \ "chr1 10 80 chr1 20 90 chr2 20 60 chr2 25 80" > exp $BT merge -i mixedStrands.bed -s > obs check exp obs rm obs exp ########################################################### # Test that stranded merge with unknown records works # correctly, forward strand only ########################################################### echo -e " merge.t16...\c" echo \ "chr1 10 80 chr2 20 60" > exp $BT merge -i mixedStrands.bed -S + > obs check exp obs rm obs exp ########################################################### # Test that stranded merge with unknown records works # correctly, reverse strand only ########################################################### echo -e " merge.t17...\c" echo \ "chr1 20 90 chr2 25 80" > exp $BT merge -i mixedStrands.bed -S - > obs check exp obs rm obs exp ########################################################### # Test that merge with specified strand does not allowed # other characters besides + or -. ########################################################### echo -e " merge.t18...\c" echo "***** ERROR: -S option must be followed by + or -. *****" > exp $BT merge -i mixedStrands.bed -S . -c 6 -o distinct 2>&1 > /dev/null | tail -1 >obs check exp obs rm obs exp ########################################################### # Test that sort order is enforced ########################################################### echo -e " merge.t19...\c" echo \ "Error: Sorted input specified, but the file unsorted.bed has the following out of order record chr1 9 30 2" > exp $BT merge -i unsorted.bed 2>&1 > /dev/null | tail -2 >obs check exp obs rm obs exp ########################################################### # Test that chrom change is handled correctly ########################################################### echo -e " merge.t20...\c" echo \ "chr1 9 30 chr1 100 110 chr2 11 20" > exp $BT merge -i b.bed > obs check exp obs rm exp obs ########################################################### # Test that a merged BAM file only gives BED3 output ########################################################### echo -e " merge.t21...\c" echo \ "chr1 10 20 chr1 30 100 chr2 10 20 chr2 30 40 chr2 42 100" > exp $BT merge -i a.full.bed > obs check exp obs rm exp obs ########################################################### # Test that precision is correct ########################################################### echo -e " merge.t22...\c" echo \ "chr2L 1 54 0.05 chr2L 65 128 0.33 chr2L 129 180 0.04 chr2L 193 317 -0.125 chr2L 321 375 -0.07 chr2L 385 448 -0.11 chr2L 449 502 0.4 chr2L 513 570 0.48 chr2L 577 635 -0.24" > exp $BT merge -i precisionTest.bed -c 5 -o mean > obs check obs exp rm obs exp ########################################################### # Test that numeric ops on non-numeric columns # are allowed, but produce a warning and null # value result. ########################################################### echo -e " merge.t23a...\c" echo \ "chr1 10 20 . chr1 30 100 ." > expOut $BT merge -i a.names.bed -c 4 -o sum 2>&1 > obsOut | cat - > obsErr check obsOut expOut rm expOut obsOut ########################################################### # Just check that the warning message from the previous # test was correct. ########################################################### echo -e " merge.t23b...\c" echo \ " ***** WARNING: Non numeric value a1 in 4. ***** WARNING: Non numeric value a4 in 4." > expErr check obsErr expErr rm obsErr expErr ########################################################### # # Test that we can get fields from a BAM file # ########################################################### ########################################################### # Test bam column 1 ########################################################### echo -e " merge.t24...\c" $BT merge -i fullFields.bam -c 1 -o collapse > obs check obs bamCol1Collapse.txt rm obs ########################################################### # Test bam column 2 gives an error ########################################################### echo -e " merge.t25...\c" echo \ "***** ERROR: Requested column 2 of a BAM file, which is the Flags field." > exp $BT merge -i fullFields.bam -c 2 -o collapse 2>&1 > /dev/null | head -3 | tail -1 > obs check exp obs rm obs exp ########################################################### # Test bam column 3 ########################################################### echo -e " merge.t26...\c" $BT merge -i fullFields.bam -c 3 -o collapse > obs check obs bamCol3Collapse.txt rm obs ########################################################### # Test bam column 4 ########################################################### echo -e " merge.t27...\c" $BT merge -i fullFields.bam -c 4 -o mean > obs check obs bamCol4Mean.txt rm obs ########################################################### # Test bam column 5 ########################################################### echo -e " merge.t28...\c" $BT merge -i fullFields.bam -c 5 -o mean > obs check obs bamCol5Mean.txt rm obs ########################################################### # Test bam column 6 ########################################################### echo -e " merge.t29...\c" $BT merge -i fullFields.bam -c 6 -o collapse > obs check obs bamCol6Collapse.txt rm obs ########################################################### # Test bam column 7 ########################################################### echo -e " merge.t30...\c" $BT merge -i fullFields.bam -c 7 -o collapse > obs check obs bamCol7Collapse.txt rm obs ########################################################### # Test bam column 8 ########################################################### echo -e " merge.t31...\c" $BT merge -i fullFields.bam -c 8 -o mean > obs check obs bamCol8Mean.txt rm obs ########################################################### # Test bam column 9 ########################################################### echo -e " merge.t32...\c" $BT merge -i fullFields.bam -c 9 -o mean > obs check obs bamCol9Mean.txt rm obs ########################################################### # Test bam column 10 ########################################################### echo -e " merge.t33...\c" $BT merge -i fullFields.bam -c 10 -o collapse > obs check obs bamCol10Collapse.txt rm obs ########################################################### # Test bam column 11 ########################################################### echo -e " merge.t34...\c" $BT merge -i fullFields.bam -c 11 -o collapse > obs check obs bamCol11Collapse.txt rm obs ########################################################### # Test that column ops not allowed with BAM if col greater # than 11. ########################################################### echo -e " merge.t35...\c" echo "***** ERROR: Requested column 12, but database file fullFields.bam only has fields 1 - 11." > exp $BT merge -i fullFields.bam -c 12 -o sum 2>&1 > /dev/null | head -3 | tail -1 > obs check exp obs rm obs exp ########################################################### # Test col ops behavior on bam file for missing values, # i.e, getting the mate reference when there is no mate. # Be sure null value is printed ########################################################### echo -e " merge.t36...\c" echo \ "chr1 10 20 . chr1 30 100 .,.,. chr2 10 20 . chr2 30 40 . chr2 42 100 .,." >exp $BT merge -i a.full.bam -c 7 -o collapse > obs check exp obs rm obs exp ########################################################### # # Test new -iobuf option # ########################################################### ########################################################### # Test -iobuf expects an argument ########################################################### echo -e " merge.t37...\c" echo "***** ERROR: -iobuf option given, but size of input buffer not specified. *****" >exp $BT merge -i a.bed -iobuf 2>&1 > /dev/null | tail -1 > obs check obs exp rm obs exp ########################################################### # Test -iobuf allows only suffixes K/M/G ########################################################### echo -e " merge.t38...\c" echo \ "***** ERROR: Unrecognized memory buffer size suffix 'L' given. *****" > exp $BT merge -i a.bed -iobuf 20L 2>&1 > /dev/null | tail -1 > obs check obs exp rm obs exp ########################################################### # Test -iobuf doesn't allow a buffer size below 8 bytes. ########################################################### echo -e " merge.t39...\c" echo \ "***** ERROR: specified buffer size is too small. *****" > exp $BT merge -i a.bed -iobuf 7 2>&1 > /dev/null | tail -1 > obs check exp obs rm exp obs ########################################################### # Test -iobuf doesn't allow non-numeric arguments ########################################################### echo -e " merge.t40...\c" echo \ "***** ERROR: argument passed to -iobuf is not numeric. *****" > exp $BT merge -i a.bed -iobuf beerM 2>&1 > /dev/null | tail -1 > obs check exp obs rm exp obs ########################################################### # Test -iobuf allows correct argument with suffix ########################################################### echo -e " merge.t41...\c" echo \ "chr1 10 20 chr1 30 100" > exp $BT merge -i a.bed -iobuf 128M > obs check exp obs rm exp obs ########################################################### # Test -iobuf allows correct argument without suffix ########################################################### echo -e " merge.t42...\c" echo \ "chr1 10 20 chr1 30 100" > exp $BT merge -i a.bed -iobuf 8192 > obs check exp obs rm exp obs ########################################################### # Test that scientific notation is allowed for coordinates ########################################################### echo -e " merge.t43...\c" echo \ "chr1 800 830" > exp $BT merge -i expFormat.bed > obs check exp obs rm obs exp ########################################################### # Test that struct vars in VCF get correct length ########################################################### echo -e " merge.t44a...\c" echo \ "19 252805 257416 19 260364 261044 19 265133 265691 19 265985 266386" > exp $BT merge -i vcfSVtest.vcf > obs check exp obs rm obs exp ########################################################### # Test that struct vars in VCF get correct length ########################################################### echo -e " merge.t44b...\c" if [[ -f vcfSVtest.2.vcf ]]; then echo \ "19 252805 297416" > exp $BT merge -i vcfSVtest.2.vcf > obs check exp obs rm obs exp else echo "skipped - could not find vcfSVtest.2.vcf"; fi ########################################################### # Test that stdin is used by default ########################################################### echo -e " merge.t45...\c" echo \ "chr1 10 20 chr1 30 100" >exp cat a.bed | $BT merge > obs check exp obs rm obs exp ########################################################### # Test that precision default is high enough for # formatting not to give scientific notation ########################################################### echo -e " merge.t46...\c" echo \ "chr1 5333587 5344172 5344172 chr1 5481008 5484749 16454247 chr1 6763278 6766882 6766882" > exp $BT merge -i precisionTest2.bed -c 8 -o sum> obs check exp obs rm obs exp ########################################################### # Test that user can specify a lower precision ########################################################### echo -e " merge.t47...\c" echo \ "chr1 5333587 5344172 5.3442e+06 chr1 5481008 5484749 1.6454e+07 chr1 6763278 6766882 6.7669e+06" > exp $BT merge -i precisionTest2.bed -c 8 -o sum -prec 5 > obs check exp obs rm obs exp ########################################################### # Test stranded merge with bedPlus files that have strand ########################################################### echo -e " merge.t48...\c" echo \ "chr1 10000 25000" > exp $BT merge -i bug254_d.bed -s -d 200 > obs check exp obs rm obs exp ########################################################### # Test stranded merge with bedPlus files that have strand ########################################################### echo -e " merge.t49...\c" echo \ "chr1 10000 20000 chr1 20100 25000" > exp $BT merge -i bug254_e.bed -s -d 200 > obs check exp obs rm obs exp ########################################################### # Test the chained GZIP file - Regression test for bug #975 ########################################################### echo -e " merge.t50...\c" echo \ "1 10000 20000 5 55554 66666" > exp $BT merge -i chained.bed.gz > obs check exp obs rm obs exp [[ $FAILURES -eq 0 ]] || exit 1; chr1 10003 10143 M100,S3M97 chr1 10358 10428 M5I1M65S29 chr1 11780 11921 M100,M100 chr1 11996 12101 M100,M100 chr1 12136 12347 M100,M100,M100,M100 chr1 12400 12503 M100,M100 chr1 12635 12779 M100,S46M54,M98S2 chr1 12819 12919 M100 chr1 13039 13139 M100 chr1 13165 13287 M100,M100 chr1 13561 13731 M100,M27D2M73 chr1 14025 14125 M100 chr1 14221 14340 M100,M100 chr1 14440 14715 M100,M100,M95S5,M100,M100,S6M94 chr1 14805 15172 M100,M100,M100,M100,M100,M100,M100 chr1 15250 15350 M100 chr1 15470 15603 M100,M100 chr1 15924 16065 M100,M100 chr1 16155 16255 M100 chr1 16314 16438 M100,M100 chr1 16561 16661 M100 chr1 16945 17038 M93S7 chr1 17372 17472 M100 chr1 17525 17625 M100 chr1 17634 17734 M100 chr1 17908 18008 M100 chr1 18033 18133 M100 chr1 18152 18252 M100 chr1 18264 18364 M100 chr1 18577 18742 M100,S1M99 chr1 19658 19758 M100 chr1 19819 19966 M100,M100 chr1 20059 20320 M100,M100,M100,M100,M96S4,M96S4 chr1 20457 20627 M100,S12M88,M98S2 chr1 20641 20741 M100 chr1 20754 20854 M100 chr1 21047 21139 S8M92 chr1 21177 21277 M100 chr1 21449 21549 M100 chr1 21834 22029 S10M90,M100,M100,M100 chr1 22061 22149 M88S12 chr1 22242 22448 S1M99,M100,M100,M100,M100 chr1 22512 22566 S46M54 chr1 22748 22848 M100 chr1 22870 22970 M100 chr1 23130 23228 S2M98 chr1 23250 23350 M100 chr1 23557 23615 M58S42 chr1 24000 24120 S40M60,M100 chr1 24248 24612 M100,M100,M99S1,M100,M100,M100 chr1 24683 24850 S25M75,M100,S12M88 chr1 24921 25011 S10M90 chr1 25055 25291 M100,M100,M100,M100 chr1 25403 25740 M100,M100,M100,M100,M100 chr1 25767 25867 M100 chr1 26053 26153 M100 chr1 26406 26506 M100 chr1 26680 26883 M100,M100,M100,S8M92 chr1 27102 27252 M100,M100,M100 chr1 27582 27785 M100,M100,M100,M100 chr1 27995 28187 M100,M100,M100,M100,M100,S3M97 chr1 28198 28298 M100 chr1 28439 28545 S5M95,M100 chr1 28577 28674 M13I3M84 chr1 28679 28808 M100,M100 chr1 29089 29191 M100,M100 chr1 29331 29431 M100 chr1 29686 29786 M100 chr1 30409 30509 M100 chr1 30809 30909 M100 chr1 31781 31881 M100 chr1 32173 32273 M100 chr1 32519 32619 M100 chr1 32732 32832 M100 chr1 32926 33120 M100,M100 chr1 33143 33289 M100,M53S47 chr1 33449 33669 S14M71I2M13,M100,M100 chr1 33842 33931 M89S11 chr1 33933 34044 S3M96S1,M100 chr1 34070 34162 M92S8 chr1 34268 34451 M100,M100 chr1 34511 34606 S5M95 chr1 35413 35513 M100 chr1 35792 35892 M100 chr1 36101 36201 M100,M97S3 chr1 36528 36625 S3M97,S16M84 chr1 37129 37229 M100 chr1 37516 37616 M100 chr1 37904 37996 M92S8 chr1 38283 38380 S3M97 chr1 38609 38709 M100 chr1 38980 39088 M100,M100 chr1 39099 39199 M100 chr1 39418 39585 M69I1M30,S4M96,M57S43 chr1 39920 40020 M100 chr1 43646 43746 M100 chr1 43974 44074 M100 chr1 44085 44185 M100 chr1 44304 44504 M100,M100 chr1 44688 44788 M100 chr1 45372 45472 M100 chr1 45738 45867 M100,M100,M100 chr1 46111 46212 M100,M100 chr1 47250 47346 M96S4 chr1 47593 47693 M100 chr1 47820 47920 M100 chr1 48088 48193 M100,M100 chr1 48445 48677 M100,M100,M100 chr1 48681 48781 M100 chr1 48832 48932 M100 chr1 48967 49067 M100 chr1 49092 49192 M100 chr1 10003 10143 0 chr1 10358 10428 6 chr1 11780 11921 3 chr1 11996 12101 1.5 chr1 12136 12347 3 chr1 12400 12503 1.5 chr1 12635 12779 12 chr1 12819 12919 3 chr1 13039 13139 30 chr1 13165 13287 2 chr1 13561 13731 2 chr1 14025 14125 3 chr1 14221 14340 14.5 chr1 14440 14715 14.5 chr1 14805 15172 12.14285714 chr1 15250 15350 21 chr1 15470 15603 3 chr1 15924 16065 12 chr1 16155 16255 26 chr1 16314 16438 12 chr1 16561 16661 26 chr1 16945 17038 26 chr1 17372 17472 26 chr1 17525 17625 1 chr1 17634 17734 3 chr1 17908 18008 1 chr1 18033 18133 3 chr1 18152 18252 3 chr1 18264 18364 0 chr1 18577 18742 1.5 chr1 19658 19758 25 chr1 19819 19966 26 chr1 20059 20320 31.33333333 chr1 20457 20627 37 chr1 20641 20741 1 chr1 20754 20854 1 chr1 21047 21139 1 chr1 21177 21277 1 chr1 21449 21549 1 chr1 21834 22029 0.75 chr1 22061 22149 1 chr1 22242 22448 0.8 chr1 22512 22566 1 chr1 22748 22848 3 chr1 22870 22970 0 chr1 23130 23228 3 chr1 23250 23350 0 chr1 23557 23615 0 chr1 24000 24120 0.5 chr1 24248 24612 0.8333333333 chr1 24683 24850 0.6666666667 chr1 24921 25011 1 chr1 25055 25291 1 chr1 25403 25740 1.4 chr1 25767 25867 3 chr1 26053 26153 1 chr1 26406 26506 1 chr1 26680 26883 0.75 chr1 27102 27252 0.6666666667 chr1 27582 27785 1 chr1 27995 28187 1 chr1 28198 28298 13 chr1 28439 28545 1 chr1 28577 28674 13 chr1 28679 28808 1.5 chr1 29089 29191 1.5 chr1 29331 29431 3 chr1 29686 29786 3 chr1 30409 30509 50 chr1 30809 30909 50 chr1 31781 31881 1 chr1 32173 32273 1 chr1 32519 32619 1 chr1 32732 32832 3 chr1 32926 33120 1 chr1 33143 33289 2 chr1 33449 33669 1.333333333 chr1 33842 33931 1 chr1 33933 34044 1 chr1 34070 34162 1 chr1 34268 34451 0.5 chr1 34511 34606 1 chr1 35413 35513 3 chr1 35792 35892 3 chr1 36101 36201 0.5 chr1 36528 36625 0.5 chr1 37129 37229 1 chr1 37516 37616 1 chr1 37904 37996 1 chr1 38283 38380 1 chr1 38609 38709 1 chr1 38980 39088 1 chr1 39099 39199 3 chr1 39418 39585 1.666666667 chr1 39920 40020 1 chr1 43646 43746 3 chr1 43974 44074 3 chr1 44085 44185 3 chr1 44304 44504 3 chr1 44688 44788 3 chr1 45372 45472 1 chr1 45738 45867 1 chr1 46111 46212 1 chr1 47250 47346 30 chr1 47593 47693 30 chr1 47820 47920 26 chr1 48088 48193 28 chr1 48445 48677 12 chr1 48681 48781 3 chr1 48832 48932 3 chr1 48967 49067 3 chr1 49092 49192 3 #chr start stop name score strand chr1 10000 20000 gene1 50 - foo chr1 20100 25000 gene1 50 - bar chr1 8e02 830 chr1 10 50 a1f 2 + chr1 20 60 b1r 4 - chr1 25 70 c1q 8 . chr1 30 75 d1q 16 . chr1 40 80 e1f 32 + chr1 45 90 f1r 64 - chr2 10 50 a2q 2 . chr2 20 40 b2f 4 + chr2 25 50 c2r 8 - chr2 30 60 d2f 16 + chr2 35 65 e2q 32 . chr2 39 80 f2r 64 -chr17 1838107 2606715 28 768608 chr17 1839247 2606715 27 767468 chr17 1839272 2606715 26 767443 chr17 1839674 2606715 25 767041 chr17 3947533 4461748 27 514215 chr17 3947644 4461748 26 514104 chr17 3953102 4461748 25 508646 chr17 3979982 4536241 29 556259 chr17 3981290 4536241 28 554951 chr17 3999199 4536241 27 537042 chr17 4008021 4536241 26 528220 chr17 4015997 4536241 25 520244 browser position chr22:10000000-10025000 browser hide all track name=regulatory description="TeleGene(tm) Regulatory Regions" chr22 TeleGene enhancer 10000000 10001000 500 + . touch1 chr22 TeleGene enhancer 10010000 10010100 500 + . touch1 chr22 TeleGene enhancer 10020000 10025000 500 + . touch1 #chr start stop name score strand chr1 10000 20000 gene1 50 - foo chr1 20100 25000 gene1 50 + bar #chr start stop name score strand chr1 10000 20000 gene1 50 - chr1 20100 25000 gene1 50 - chr1 10003 10143 CCCFFFFFHHHHHJJIJJJJIGIIIJIGIGJJJJIJJJJIJIIJJDIIIJJIJEHEE@GAHHGE@CEFB;A>AB=??5?B?2??;DBBFBCFGGDCFGGGGEFAHA@BEFE>AA############################# chr1 11780 11921 @@@DDABB?FBHDF82FGIGHEHBFE*:@BBFG??@AHI>GCHGGIEI<=B,3;6.>CD@>C:>>@;@:@@CC5=CCC@,CCCFFFFFHHHHHJJJJJJJJJJJDGHJIJIJJJJIIJJJJJJJJJJJIIJJJJJHIIJHHFFFFFEDEEEEDDCCDDDDDDDDDDDDDDDDDDDDCDDD chr1 11996 12101 CCCFFFFFHHHHHJEHHIJJJJIJIJJJIJJJJJJJFGIIGHHIIJIIIJDFHIJJJJIJJJJIJJJEI7?EEH@CDFFEEEEEEDDCDDDDDBDDDDDD,@@CFFFFFHHHHFIIJJJJJIIJIJIJEIJJJIGIIIGEHIJJIJBGE>FFGHGIIIIIIJJGH@DEHHAEHHFFDFCFECCCDD?BDDDCCDDCCDCD4 chr1 12136 12347 :@@:;>>;;5;>;C>3>6=53=;.=??::IJHHF@FDEGEAGE;GGFFFADDBDD?<@B,BCCFDDDDHHHHHJJIJJJJJJJJIJIJJJIGHIJIFIGJJJJJIIJIIJJDGGIHHGGHDFFFCEDBDD=BC>CB?B@BDDDDDDBDDDDD?@B@BDCBDDDDDBDBBDDDBDDB?DDDCCACDCBBBFFHHEEHJIJJJJIGIGJIJJIIIJIJIJJJJJIFJHHHGGFFFFFBCC,?@@DDDDADABFDFGHAEDH;BB8? chr1 12400 12503 8>3CCCDCA<@:BA?@A9;/;897@CAFEBFFFFHHIGJJIJIGGHFIJJJIJJIJJIIGIIJJIHFC4HHGJJJJJIJIJIJIHHHHHFFFFF@C@,BA>CDCECDDDDBDBCC??=ADDDDEDEEFFFDBEHHHGJJJJIJIJJIGIGIHCJJJIJIJJIJIJGIIIJJJJJJJJJJJJJJJJHHHHHFFFFFCCC chr1 12635 12779 BBB@DDDCCCAACCDDDDDCDDDDDCC@ACCCCCCCDBAHE>IIHFJJIIHGHFD@>JJJJJJIJJHEGGJJJIJJJJJJIIJJJIJHHHHHFFFFF@CC,##############################################HGD@AF<7??))*:***1?**91**3F?:29<+<+:@:)++2<22+:D8DA:+?,C@@DDFFFHHHHHJJJDGFEHEFBDGHEB?AHIGIIIIIIIEHHIFHHGFFFFFFDECE>>@BBC@?B??BBCCCECCC chr1 13039 13139 C>?AAC>:>@>CC?DC?DDDDDDDDDBBAACEDDFFEE?EIGIIG@GFABACHBIJJIJIH@JIGGIGHFFDGG@BHCECGHGBGDFHAGHHFDFDD@C@ chr1 13165 13287 CCCFFFFEHHHHH=GHEGIIIIHHIGGGHGJ@AHEHEHEIDGIIFHGJJGH@GGIIHHHFFBCBEEEDDD?BBDAACDD,:3C?@>>A>?;29EEHEG@GG@=/56BIJJIJGHIGIHFGEGGIIJGHGGGF=IIGHFE@JIGHFDFCHFFFFD@@@ chr1 13561 13731 DCCCADBDDDDDEDDDDDDDEDBB>DEEFFFFFHHHHJIHIJJJIIIIGDJIGGIJJJIGJJJIHJJIJJJJJIJJJJIIJJJJJJJHHHHHFDFFFCCC,CC@FFFFFHHHHHJJJHIJJJJJJJJHIJIGHJJJHIJJJHGIIIIGHIIIHIIEHHHFFFFC?CCBC@CEDDDDDCDDBDDDDDDDDCDCCCD?CD@CA chr1 14025 14125 CC@:3597BBBCDDDDDDDD@CCAADFFFDE??HJIIGGHIIHFHGGHCJHGJIIJJJJJHEHGJJJJJJJJIJJJGGHHHFFFDD?@B chr1 14221 14340 @C@FFFFFGHHGHIIGHGGHGHDHGIJJIJICHIHJJJJGIJJEGEIJIIIHJIIGIEIIIIG=CGHEHHHBED>;>CECD@??@=BDCDDDCDCADDBD,@CCDFFEFDBF?HIGIBHGCHGGGEGGGEGIIIIIIIGHIIIIIFHIIIIIIIIIFGIIIEEEGHEBDDEFFEECECCCCBBBCABBBCBB>BBB?,@CCFDFFDDHFDHBGBHGIGGIEIIIGHIIIIGIIIIFHGBGCFDDGGIGIIIIIIIIEGHHHFFFEA?A??B;>>A@CCDACDCDBAACACCCCDA??A,@@@FFFFFFBFHHDHGHGDHECHIJGHIBFFGIGGIJFHGHGBFHHIIJFGHHGI>@EHHEB@@?A@CE>C>@AC>CCCCC9A>@??CC@>9ACB#####,CCCFFFFFHHHHHJJIIIFHIIHGEIIJJJJIJJJIIIGHIIFIIJHIIJJJJJJIIJIIJJEGHFDA?A;@CDDD;@@A,B9B@ACCBDDCDDCACCDB@CDDDDBBBBCDCAAA@ACB>BFEDEEBIGHGGJJGIIGDBHEGFDFFGIIHDFFJHEHHFD?DDDB?@<@,######B?AA82+(2?<443:DC@:>4CC8(00@<CC8<9(991==99EGCGF@CIGC=9FFFHHHGGJJFIJJIGHGJIJJJJHHFHHFFDDFC@B,CCCFFFFFHHHHHJIIJCFHGGIJFEHIIIGJJJJJJGIJJJJJFIJJJHHFDC@9@CCDDDEEDDDDD?DDDDDDDDDDDDBBC?CDCDCACDDD(>AC,>44CA9<8A<<8829.BB>>?B@988(->:<89+B?BDDDDDEECFEC@@HEEHHHDDC7JIIGGIGGIGIHGDDIGJIIGHFACDDCDDCDDCADDDDBDCACA;EEEFFEFHEGHIHJIIJJJJJIJJJJJIGJJJJJJIGIJIJJIIGJIJJJJJJJJIJJIHHHHHFFFFFCCC,DBC@CBD>DDDBDDCCDDDDDDBCFFFFFHBHHHJIJJJIJJJJJJIIHFGIGGJJJJIJJJJJJIJIFJIIJIJIHJIIFJJJHJJHFHHHFFFFFC@C chr1 15924 16065 CCCFFFFFHHHHHJJJJJJIIJIJJJJJJJJJJJHIJHHJJIHIJJHJJJJJJJJIJJJJJIJIJJIJIJJJIJJJJJJJJJJJIJJJJJHHHHHFFFFFCCC,CDDDDCDC<;BDDDDDDDDDDDDDDECFDFFFFEHECEAGEGHEG@JIIIJJIGJJHGJJJJJGIJIJJIJJJIIJJIJJJJIJIJIHHHHHFFFFFB@@ chr1 16561 16661 CCDCCA8(?CCDEDEDCADDDBBDBDDCDDDDDDDDBDDBDDDCDDCDDDDDDDFFGGIHCJJIJJIIJIJIJIJIJJJJIJJIGGEHHHHDFEDDF@@B chr1 16945 17038 ?@=DD?BDBFDFEGIAF2BB;D@DAB.8=53=D?CCAEEC3@;@EC:63;=?B35;29?8AB,5>9(:+4C?CA?DDDDCC>:';8?@GEHCHCIHFGHEIGGGHGFBDCCBDACDDDDCDCDDD<<<@0<2>B:@BD:5>CC>>ACDB<<8:CCCDC chr1 17908 18008 CA@:(89??<25&59&50059A?A83BDDB>BBCBFHB@1HHIIGCIIHHDHDFEEHF@@HEGGAAD:AHEDDFD@@@ chr1 18033 18133 >CB?A@A>5,9AC@@DDCCCC>>5.6.=@@ECFHCFHAIGHGGGJIHGEHGGIEIGHHF>FDEHHEFC;GIHHDHFDFFDD<@@ chr1 18152 18252 B@CFFFFFHHHHHIJJJGHIHIJCHIJDFI?GGHGGIGGIJJJJJJIGGGIFGIJGHEBFDFFDD?B?>AC:ADB@BBBCDB:A44::>@CCCC:83<:ACAC?IJJGGHBHGGCIIJHGHJJIIHGIJHHIGGAHEHIIHHGHHFFFFFCCC,@>9?BBBBAA?AC@@?;6;>CC@B?BFFHEEHHEAD@D>@C@7@=FGGFCCC8B@CBDHHF?@D;3(;=;AB?@?>?1(42<8:A:>AC chr1 19819 19966 CCCFFFFFHHGGHHHIJJJJGHJIJJIIEHHJIIJJJGGIIIIIJIFGIHHHIHIJJJIIJIJIGIEGIGHGHFFFFFDEED;3=>@>CCDDDB@9:?A@,CCCFFFFFHHHHHJJJJJJJJJJGJIJJJJJJJJJDHGJJJJIHHHIJJJHGJ@DHHEHEFFFFFEEEEEEEDEDEEDD?DDDDDDDDDDBDACDD?@DD chr1 20059 20320 CA:4(?<53:::5CCC>C?C@>C@BCCCCCCCA>>CC>CC@B;@DCCEHACE>D=AD>DCECC;A:EEGHF@EEHGCHEG=GGGFA:BHFDFDDDDD@@@,@CCFFFFFHGHHGIIEGHHAHHGJIIGIIGGEEFHHFGGDCGGGIICHGGG;?DGIJII=EBD?CF>CCC>BBDD?BCDCDDDD?@CD?C(:@@CA?CCC,@?@AD?BDF:C8F:CGF8?CDGFI@GFEDD;B2?BB@FB>F@FFFIFC77?CCB>B>3;>;A@C6;;>ABBB(:@@@BDAABABB>A@AA>><>B@59<@,C@CFFDEFHHHFDFHIGIIEHGHGJJJJJGGGIIJJIIJJFIG?FHGFGFGE@DCHHJGAEHFHHHFFFF>CCCDEDDDDCDDADDBBBDBCCADCDCDD,DDDCCBBDBDDDDDDDEECEEFFDFFGHJJJIJJIJIJJJIJIIIFJJJJJJIJJJJIJJJJJJJIJJJJJJJJJJJJJJJJJJJJJHGHHHFFEDFCCC,:CCACDDDDDDDDDDEEECEDFFEFFE=EHHEFIIGIIJJIJJIJJIIIIHEJJIGEIJJJJJJJJJJJJJJJJJJJJJJJJJJJIIGGHHHFFFDFCCC chr1 20457 20627 CDCCAAIHHF4JIIGGJJIGJIIGHGHHFF>DDFFFC@@,############CB??>@CEEA?.3@A?GGC8)78/)=4=8>B?D?94?<>F@HGHF9?:4F9?AA;CHHHA?2;?C>C>3>>ADCDBCBB?A??BDC>BB chr1 20754 20854 CCCFFFFFHHGGHIIJJJIGIIGIIJIGGGJEHBHIIJJJJJIJJJFFHGBCFFDFHIJIIJIHH=ACDDFDFEEDCCDDBACDCDDDCCCA9A9ABBAB chr1 21047 21139 ########@>>9B989AC><>@DD@8@CC@>3CA9+9DDBAAABA@>2CABA83838338<<296(?883(B@507:GAAAA:DB>DFD@@@,B@@FFFFFHHGGHGGIIJGIIIJGIGIGIGGIJJIGIIGIGIGIHEFGGGEHGIABHFFFFEEEEDDD=CDCDDBC?>ACACCDCACCCC?>28<8??@C,BCCFFFFFHHHHHJJJJJJJJJIIIJJJJJGIIJIJFIJFHBFHEIIJIGIGGHIDH==CHFHFF?BD;?BBDDDCDCCCCCACDDDDEEDEDDDDDACD,@@@FFFFDHFHHHJJGGGGHGIIHGGGIIIIIIIIII<@FDHIJJJIJGIEFFHIJGICHH@FHIHIIIIHGHHHFFFFB?CDDDD3>CCCC:ACCBBBD chr1 22061 22149 +=1++=?:+=C??E??:AABA+G411:1:1:)::B2??DDB<*9=..).8@:98=3@7='-;;B@32;6.6;5?A############ chr1 22242 22448 #DBDB>:;3CCCACC?EBFDFFHHHFFHGDAE@EG@5GIIGIGJJHGHHGGB4D?9CGG@GHHFDIHFGGHDGGDBHFFDDAAFD@@@,BB@FFFDFDDHGHJIBHIJIIIIIIGIIJJJCHIFGGIIGIJJGIIJJJJIIIIJJIGIJEHHHHFFE@DFACEEECDDDDEDEDDBCCDCDDDDDD>CD,DDCCDDDDDDDDCCDDB@@BDDEECDFFFFFECBHDGHJJJIHC;A=IGHFCIIGJIIJGHHIIGAD@BCEIEIJJJGGBIGIJIGHF?GHHFFFFFCCC,DDCBBDA:ABDBDDDDDDCEEEEEEEFFEFEDFHHHGD;JIJJJIIJIHEFJJGGGJJJJJIJJIJJJJIJJJJJJJJJIJJJJIJJHHGHHFFFFFCBC,DDDCDBDCCCCC@CDDDDDDCADC@EBCCEFFFFEHGFHGHGIIHGHEHHCIGGCHAHGFBHDHGHDFJIJJJIGJIGJJJIIHFGGHHHD?FFFFFC@@ chr1 22512 22566 ##############################################D?)1B90*:*?*:**?13BE?81;CA24@FAFFACDAE<+?BDHIEGCF@=)8=;DHGGF;CCBDDD>AA>>A?@>BBDCDB>>8AB<(4::?3:CCC chr1 23130 23228 ##A;(DECDDE??@;DHCE?A;@D=4CC@7@CDFB3CF9D9EF?B*@DCEDIHEHGIGDEGG>CEGIGJIIIHE>HBDGHCAFGHEGDDFAFDFFFD@@@ chr1 23250 23350 B<85BCCC>ADCC=@@9,;=;>A=B@DFEEHGHIE@=ADC@F=;=GHB@B@BAFB?B?AIIGC>IHGG?A?<0?=FDD??= chr1 23557 23615 =+?DF+++2+2)<))))1*1*)1):BF?8*)?0('(.8@=FG)7=@C?;?>CC@6;=B########################################## chr1 24000 24120 ########################################A9?.@((3=;;=2FB;F?=?;990*B9?1)?;G?A:BGGEC@FFAFIFBB@>BDDDA@AC@@=AA;>;>5>>>??A9A5>ABBB:3<>@? chr1 24248 24612 CC@FFFFDFFHFHJIJGJIHJJIJJJJJJJJJIJJJJJIHIJHEIIJJIIIJJJGHIJJIIJJJJIEGGGIGIIIIIIJIJIGHHEEFD>?@CCB?BBCC,@@@FFFFFHFHHHJDHBGHHGIEHHBHICEDHIIGHEGIHBGEHHIJDFIIGHJJIGGGEGIJDHIIIGJIIIIIFHJICHIHFEEFE:A>@@5=?@B5>,?C@EH9<:):C?FGCC)7?D@?@=FGHI@D@FA@EHE;A(.?C@>((;;3;>>@5>??B9:(:@3:(5::<5<>BBB#,DDDDDDDDDDDDDDDDDDDDDEFFFFHHHGHHHJIJJIHHF@IHGFFCGFIJIFJIHFIIIGIIIIHEHIIGIJJIJJIIJJIJJJIGHHGHFFDFFB@C,DC@@D@@CCCB??=DDDEEEECFFCFDE=EAHIJGGD>@GGHHEBIF@FDHGJIJJJIJJJJHFBJIIJJJIGDIHGEIHIIIHGFGFHFHHFFFDF@CB,?<@DDDDDH?+C@GHHGG:CGCEFGGEECDD87(?DBBHBDDHGIGIFEHHDDEE@CACCC=CCCCC@:5@A(39>>@@;2DHHEC*FC:@:<+CGE?GHEFDHFFDFA+DBF@@@,@B@FFDFFDH>FDHHGIJGJGHIJIE?FGDBH(;;@@9FEHG=?AEEEFF@CAEC(>;>CCC@@@C::@<:C@CB?@CCAA@CD9<89ACD@8,############CCCB@:A>+(33?<:?:(&&555(CCC?BDCC888'9519((,?:5'4@)F@B9EDDB@;?9005?@DBB;)=77?=@D@AHEFHCAIECJBFC@5>>@ADDCDFEDCDDDBBDDDDDDD<:@@CDDDDEDCC,:==D;DDAHHHHHI2A@>HIBGHIGHIG@HGE=FGGHGHIGIIIIGHEICCFHEHIIGGHE:@@@DGHEEEDFFF@DCAEEDC?C=C@CCC:,9?BCCCB,CCCFFFFFHHHGHJIIJJJJJJIJIJIJFHHIIHIIIIJGGIDIJIJCHIBGGIJIJJJJJJJIIHHEEEFFDDDEEDCDDDDDDDDDDDDDDDD?CCDC chr1 25403 25740 <@@FBDDFHFHGHIHI@=DEBGGHIIIIIIIIIEEBGGGHGBHEBD*?D>DH=FFGCDHEC:?B,909B>AA>DCCCDCCDCCCA>?A;(6B?=/FIGE@=CF@GGCGHD?CGIIIGGIGB:IIGGEIIHG:EDCCDDBDDEDCEFFFFEFHEGHHEEAEEG@GIIIHGFEGFCIIIIHBIIIIIIIGHC4GIIIHCFFIIFIHHFDEGGGHEFCDAFF8FFFFC@@,DCBDDDDDEEDEEEFFFFFFHHHHEHGGGIIIJIGJJJJJIJJJIJJJJIGIJJIGGHDIGHJJJJJJIJJJJJJJJJIJJIJJJJJHHHHHFFFFFCCC,@@CFFFFFGHDHHIIJIEIJIGICEGIJIGHGIJIIGGIJIIDEGIIIIJGGHIJJGG;@FHHIIGGHHHFEFFDFDCDEEDDDCC9A@BBDDBDC?C>C chr1 25767 25867 CA>+<<0?A;@EB?.)?)?EEE@EIG@5IHECEHGGF?9)00D@EEGGBHFCCGGDF>IGGHJIJIIJIEGFDHFFDAFFF@@@ chr1 26053 26153 CBBDBBDDDDDCDDDDDBBDDBDB?DCDFFFFHGHHJJIIGGGIIIJJIIIHG?JIJGJIJJJJJJJIJIGIJJJJJIHFAIIJIIJGHHGHFFFFFCC@ chr1 26406 26506 CC@FFFFFHHHGHIJJIJJIIJIJIJGJIHIHFHIJJJJJJJJIJJIIFGFGGEHIGHIJGJEGGIJJIJJIJJJEHHHHHFFFFE@6;@AC@CDDCDCC chr1 26680 26883 BCCFFF:DFHHHHJJJJJIIIJJJJIJIJJJJGHIJJIIIJJIJJIIDGIFHHGGJJJJJJIJJGIGGIHIIIGH?DEED@CEEEBBDCDDCDDCCDCCC,CCCFFFFFHHHHHICDHHIIIJJIIGGIJJJEHHIIIJJJGHDGIIJIIIJJJIJIIIJJJGIGIHDEHCHFEFEDCCDDDDDD@9@DDDDB@BB>CDDD,B@CFFFDEHHGHHJJFGCGEGGGIIIIJJJJIJJIJJIHHJIGIIIHIIJJJJJJJI>:=BBBB/;@BDBCCBDDB@>ADEA@@CCBCBCCC39<229@<,########DDB>@@90<=@@CDDBB@C?EEEC>D@6HHHFCGEIGF>GHHIGEGFGHHGDJIGHIHHFFDJHGJIGGCHGIGEGHHHFFHDHDEFDA@@B chr1 27102 27252 DDDDDDDDCDDEEDDDDDDDDDDCDEEDEFFFFEAHIGJIJJIIJJJJJJJJJJJJJJJJIJIJJJJJJJJJJJJJJJJJJIHJJJJHHHHHFFFFFCCC,CDCBDDDDBCCA>@;9DDCA?CA?=A;;6EEBC>CB@=2CEE@3GIJJIJIGGJJIGGJJIGHHIGIGHIGHHDEJJJIGHEJIJJJJFIHFCHCGGGJIJJJJIIHHFFHFDFFFCCB chr1 27582 27785 @B+ADADDDDFHDDG9A@HCHIC4FHGGIJGIJIFIBCGGGGEGIGBDBFGGHB@FGC<@CGI@AD;CEHHHHF@C;BCDEDE>ACCCDDDDD@3>@@C3,@CCFFFFFHHFFHJJIGHGIJGHIJJJJJJJIJIJIJJJJIHIJIJIHJJGIJJJJJJIFIJIGIJJJIJIICEGFHFGHCHFFDFFFEDEEDEEC@CCC,@@@DDDDDFFHFHIBAFEEHEEHHDFB?>BGHHHGEEHIIFEHCDH>DG9DFHGGIGAE>BC>BF@=AEHCACDEEDEDACCC@CC,CCCFFFFFHHHHGIJJJJJJHHJJJJJJJJJJJJJJJJJJIJIIJIJJJJJJJJJJIJJJJJJJJJJJJIJJJJJHIEHHHHHHHFFFFFFFEEEEEFED chr1 27995 28187 ECCDCDCCCBCCEEEEHHFCEIHIHIGIIEIGGIHGEE>GIIFIIIIIIIIIIGGIGGGIIIGGE?IHF?IIIGIHG@GEIIIFGEIHFHFAADDDD@@@,CCCFFFFFHHHHHJJJJJJJJJJJJIJJJJJIJJJJHIJGIIJJJJJJIJHHGHHIJJJJIJJJJJJJJJJHIHIIIJGHICGHHHHHHFFFFFECCEEE,EDDDDDDDDDECEDFFFEHHHHHJIJJJIIGIGHFHIIJJJIGIJGGGDJJIJIIJJJJIHFJJJJJJJJJJIIHHIIHJJJJJJJJHHHHHFFFFFCCC,CBCFFFFFHHHHHJHIJIIJIJJJJJJJJJIJJJJJJIJJJJJJIJJJJJJIIJIIJJJIJJJIJJJJJJIJJJJHGHFHIIJHHGHHHFFFFDDEDDDD,DEDDCDDECEEEFCEFEBA=HHJJJGJJJIHG@JGGJJJJJJIJHHGIIHJIHJJJJIJJIHJJIJIJIJJJIIJJJIIJJJJJJIJHHHHHFFFFFCCC,###?:9:@CAEDC>>C>5CC@AA>>>FFDDC?@GCDBDDD@@< chr1 28198 28298 CBCFFFFFHHHHHJIJJJJJJJJIIJJJJJJJJJJJJJJJIJFHFHIJJEHHIJJFIIJJJJJJJJJJIJJJJHHHHHFFFFDDDDDDCAADD9ACDDDC chr1 28439 28545 #####C@CDDDDCDDCDDCEEEEEDDCFFHHFHIIJJJJJJJIIHFIGIIIIIIHFHAGIJIJJIHJJJJIJJIIGGGJHGCIIJJJHGHHHFFFFFBC@,DDCCDDCAEDACCB?5DEEECCBCDDGHHHFGJGEGHIGJGGIHCIIGIIGIHGGHBIHFHGGDGIIIGGBJIIJJIIJIJJJJJJJGGHHHFDDFFCC@ chr1 28577 28674 >>>@>8??2<<2A<8DDDDBBDDDFHGHHHHJIJJJIJJJIGJJJJJIHGJIGIJJIJJJJJJJJJJJJJJJJIIIIIJIJJJJJJJHHHHHFFFFFCCC chr1 28679 28808 CCCFFFFFHHHHHJJJJJJJJJJJJJJIIJJJJJJJIJJJIJJIJJJJIJIJIJGJJJJIJGHHHHFFFFDDDDD=@BDDEDDDECDDDDDDDDCDBB>@,CCCFFFFFHHGGHJIJFIJJJJFIIJJGIJJGIEIJIIDGGGIIIGHIFHHHHHFFFFFCDDEDDDD>@@;@BCC3?ACCCCCBDD5?C?CCCDBB9@BBBDDDDDDDDDDB>DBDDDDBBDDDDDDBDDDDDDDDDDDDDDDDDDDBDDDEEDDDFFHEJIHGGJJJJJJJJJJJJJJJHHHHHDFFFFCCB chr1 29331 29431 CCCFFFFFHHHHHJJJJIIJJJJIJJIJJIIJIJHHHFFDDDDBDDDD?CACDDDDDDDDDDDDDDBBBCCDBDDB@B@BBBDDD>B9BBAACB@7>@>B chr1 29686 29786 BB7DDCDC?9B@9@BB>C>>>CEEDEDDDCDCDCCA:EDFFDFFFEHGHEGJJJJJJIHGHEIGIHIGIHGIJHHGJJJJJGIIJIJJJJIJJHHGHHDDFFD@@@ chr1 31781 31881 @@@DBDFDBH;FDEBFDGEFFEFHD@FFE?E?EBDDFHICADHIIFIGBHDEGGGGBAHIEE;EG@GCHHEEHB;>?BCEECCEEBCCB@BB?BBDB?4: chr1 32173 32273 BB>@9CCBAAC=553@;>CCCC>>CBD?FEAAHCCED=E=CIHFBFAEACGAGGHDGAD99HCGIHGGF=IJFJJHGEIHF@BFHHFF;?DDB@B@ chr1 32519 32619 @CCFFDDFHHHHHJDHIIIJJJJJJJJIJJIIIEFHIJIJJJJJIJJGFEGIHGJJJJIGIFFIFHIHCHBGBGHH;;;A2,8@C@CCCC:5<85@BCA chr1 32926 33120 DCCADCEEEC@@DBB@;DHHGHGIJGHJJIIIHFDIIIJGIJJJJJJIIGJIIGJIIIJIJIHJJJJJIGIIHEIIIGJJJIJIJJIHGHHHFFFFFCCC,@@CDDEFFHHHFHJJIGHI9FFCGHBCC2A@FGGI@?BGGDG4?FHAABFD>@4;;=@@E;DEC@EC=E=>@;;B;?6@>CEDEBD;; chr1 33143 33289 6C@;(36;.)@;CEA;?)=DC3@@EF@:EGFA=4@B?EHE9*CC4@EH@D?IC@=BDCA9CCDC?BEC;:FFDFFGHIIIIHIIIGIGGHD;?HBE9BHGIHHFBD9FE:+:CHC;)??E*::*?BF?BGBG**090**/*0?F*9(8=CBC.8778@C;@.).)7?=AA73;@########### chr1 33933 34044 ###@:9?;99=(EA?;>?>FFFE>>:=74=B;8.))88.)(3B;?CC;>6;5;ACCC######## chr1 34268 34451 C>9,9A;89=::@>A;;@CB;;=:AA7@=D=A;FEHFB@IF@B?@D:A:>DDDCAA92DBBDB????66>@A;;;DDEHHDE=.2F@@@B=====;ECAIHFBDB9??B??:1HD:@@HFACDB?CEHBHHFBDEADD@8<8.??8?CCBCCCCCCCCC>6;A@@D>B@:FHHHFGEHIHIHBHIIHFF??FCHEFHFFDFFDAB@6@>CCCCDDD9>>?B8AB### chr1 36528 36625 5+8CC@DDDDDDCBC?B???DCDEDBFFHFFHCC;GIGIHGA@;GIJJJJJIGEJIGICG@IIJJJIJIHFIJJIIIEIJJGHHHHAFFFF@@@,################DDDDC?3?:(>A>98;82BB?+?ACC?5770IFIGIGGIIJGIGGGHEJJJJIGGGGCJIHHHHHFFFDFCCC chr1 37129 37229 CCCFFFFFHHHHFHIIIGIJIJIJJJJJJJIJJIJJIJIGFHIHIIGIHHGJJIJJHJIIGIIJJIII@GGGGHGIEGIJJHHGHFFFFFFFCCCEE>C> chr1 37516 37616 DBADBABCCCCCAB=BACCAADA>9<9?BBC?9?:@C@CC?B######## chr1 38283 38380 ###BB>:>55,;@@BA>>ECDFCCB>DHEEA=:@:GHCAGGGEFF?DB?BHIGHED@HD?CHFC3EGG=F?EHGGGDFBIIIHDHEJHHBFFFEDDA<@@ chr1 38609 38709 CCCFFFFFHHHHHJJJJHGHHGGIGGADDHIHFBFHIJIGGCECDFGHGGIIIGIEHFGIIIGGHJIJJEIFIIGCHH>A;CFFFFFFFADBCB?CCCAC chr1 38980 39088 555553A;AC@@AFA;ECC@;F@DC?773AEA?ABA5()HEC=)9??99?9;DFD@CCCDDDCADD<>@@@:ACDD@CCDDC chr1 39418 39585 BCDC>>C>@@DDDCCADDDDDDDDCDDDCDDDDCCCDDCCDDCBBDDDB?DCDCEEDDC>DDDCCAA73DGIDGHFHHFIJHGC+IGFGHDHFEEDD@@@,####BDB?<90&B>B?9,<9GHGGFAFDHHDDFDDD@@@,@@@FFDDFDFHBBFHEIBHIBE@EGHIIIGGIGIIE3?F?99?99B9BA=;A-:;>C########################################### chr1 39920 40020 >@:>CDCC@::C>:(:>:8IHFAGCHCIIGIEIIHGHDFHHFDFFDFC@@ chr1 43646 43746 C@CFFFFFHHHHHJJJJJIJIHGIJIJJJJEHIJJJJJIJJIJJJIJJJIIJJJJJIJJJIIJJJJJJIJIIHHHEHFFFF@AECCCEDDDCC;?CDDCC chr1 43974 44074 CCCFFFFFHHHGFIIIJJIJJJJJJJJJJJJJJJJJIJJIIIGIIJGGEGIIIIGHIJJIIIIIHHGICHIGFCECEFCDDCDEEEDEDEDEDCCCDDDD chr1 44085 44185 DDCCCBAA>(C@C>;CCCCA>DDDDCAB;;DCECACEDEDFEFEB>E?A?C=3=;CE;AIHF=8IHDIHAHF>DJJIHFFBB>GIHGDHHHHFFFFFB@@ chr1 44304 44504 CCCFFFFFHHHHHIIJJJGIJJIJJIJJGJJJIJIJIIIJJJJJIJJIIJJIGIJJJJJJJIIJJJJJJJJIEHCCHHFFDFFEEEEEEDEEEDDDDEDE,CCAFFFFFFFFHHHGHJGIJJJIIIJIJIGJJIEIJJJIIGJCGIJJJJIJJJIIJJJJJJIHJJIJIIIHJHEJIHJIJJJJIJJJHHGHHFFFFFCCC chr1 44688 44788 DDDEECDDDEEDEFCDDDAECHHJJJJIEIGGHJJJIJJIGJJJJIJIIHJJIICF?HHIJJIJJJFJGJJJIIJJJIJIJJJHHGHFHBFF>FFDDCBB chr1 45372 45472 @@BDDEDDHHHHDHGIEHHIJJJIGGEFAHGIGIGGHIIJIIJEICEFHGGEHHIIJGHGHGGGHIIJJIIIGGHGFHHFDFFF;@CEAEEADDDDCDDD chr1 45738 45867 CCDDDBDDDDDEDCDDDCEDEDEFFEFFFEC?GGIIIIIIGHFAGHEDEGIJICJJIGGGIIGCGJIHJIGGIIIHCCHGECIIIJJHHHHHFFEDF@C@,CCCFFFFFHHHHHJJJJJJJJJJJJJJJJJJJJJJJJIJJJJJJJJJJJJJGGJJJJJJJHHHHHHFFFFFFEEEEEEEDDDDDDDDDDD?BDDDDDDDD,CCCFFFFFHHHHHJJJIJJJJJIJIJIJJJJJJJJJIJJJJJJJJJIJJJJJIJJJJJJIJHHHGHHHFFFFE@CCDDDDDDDDCDDDDDDDEDDEDEED chr1 46111 46212 DDEDEEEDFFFFGHFGHHJIGIJIGJJJJIIGJIIIJIIJJJIJJJIJIJJIIHJJJJHHGHFJJJIJJJJJIJJJJJIJIJJJJJJHHHHHFFFFFCCC,DDEECEDFFFFHHHHFGHGIIDJIIJIJJJJJIJJJIJIJJJJJIJJIJJIHHJJIHFFCGEJJJJJJIJJJJJJIJJJIIIIHJJJHHHHHFFFFFCCC chr1 47250 47346 @@@DDDD?AFDDFGADGBEACHCF@?FGH@9CCFGE::CDH;CDDGCG)8CFHIBHABBB:@A@@C:,5>?CCBBCC#### chr1 47593 47693 C@5BCACAC>EEECAE@=A=?;GGIGEAD@EEGFCFFBFFFDHEGFHBHEEGIEGGBBFCGIGAGCHBEGEHFCFBGJGCADD?BD?@@>CDCCCC>:A>CDDDDDCC@@CEAFDFFFFHHHGGHHIGIIJIHDFCIIHIHIGHDIHGIJJIHDJJJJJJJJJGIIGJJJJJGHGHHHFDFFF@CC,CCCFFFFFHHHHHJIIIJJJJJJJJJJJIJIIIJJJJJIJJJIJJJIJJJJJJJJJJJIIIIJJJIJGJJGGHFHHHFFFFDDAACDDDDDEB(5@AC>5 chr1 48445 48677 @?@DFDFFBHFHHBGBHIGGGGHHEIJEHGGGGHHGGHIJGGGAGGGIJIGFHIGGIJEFHHAB;;@B?;AEACECCDDDD@CCCDDDCCCCD(5?ACCD,@@DEDACCEFEFFFFHFEGGIIIIJJJJJJJIJIGEGIIJIHJJIHIIGGJIGIGJIIGJJJJJJJIJIIIIGHHJIIIFJJJJIJHFGHHHFFDFFB@@,@CCFDEFFHHHHHIIGHGIIGIEC?FGHHHFG9EGGIGIIIIIGIIIIGIHIIIIIIGIIGGIIIIIIIIIIIHIIHFHHFHFFFFFDCCAADDD??CCC chr1 48681 48781 @@@FDFFFGDHHHIIIIGJCBFDHIGIIIJIJG):@GFECFIAHGIIIEFHHGDGGFGCAGEAEHHEEFC@B=CCCDCDCDDEAACCDDCCCCACC?ACC chr1 48832 48932 >A>>CCCC=BCDDDEEEEEEEDBEHJIGHH@CIGGFGGIJJIIICGJIGG?3CCCCCA?FDCEEA>EEHIIGIHFHCJIIHHEGC=GHGFCGJIIHHDCIGGBIIGGHFHIIGIIIHFAHEFCHGE>FGDFFHADBDBD@@@ chr1 49092 49192 CCB;CC@CB>>CDEECCA?3;;37C?;?=CGGEIGIGCAIHDBIHGIIGFDDFAIIHCD?GDGDADC?DFFEIIGJJJGIGIIJIIJHHFFDDDADDB<@ chr1 10003 10143 10024.5 chr1 10358 10428 135524043 chr1 11780 11921 12189 chr1 11996 12101 12401.5 chr1 12136 12347 12225.75 chr1 12400 12503 11998.5 chr1 12635 12779 12504.66667 chr1 12819 12919 13187 chr1 13039 13139 12681 chr1 13165 13287 13190 chr1 13561 13731 13595 chr1 14025 14125 13629 chr1 14221 14340 14607.5 chr1 14440 14715 14683.33333 chr1 14805 15172 14904.28571 chr1 15250 15350 14837 chr1 15470 15603 15068.5 chr1 15924 16065 16326 chr1 16155 16255 16561 chr1 16314 16438 15944.5 chr1 16561 16661 16155 chr1 16945 17038 17372 chr1 17372 17472 16945 chr1 17525 17625 17908 chr1 17634 17734 18033 chr1 17908 18008 17525 chr1 18033 18133 17634 chr1 18152 18252 18577 chr1 18264 18364 18643 chr1 18577 18742 18208 chr1 19658 19758 20059 chr1 19819 19966 20224 chr1 20059 20320 20137.5 chr1 20457 20627 20117.66667 chr1 20641 20741 21047 chr1 20754 20854 21177 chr1 21047 21139 20641 chr1 21177 21277 20754 chr1 21449 21549 21834 chr1 21834 22029 22086.25 chr1 22061 22149 22512 chr1 22242 22448 22052.6 chr1 22512 22566 22061 chr1 22748 22848 23130 chr1 22870 22970 23250 chr1 23130 23228 22748 chr1 23250 23350 22870 chr1 23557 23615 24000 chr1 24000 24120 23989 chr1 24248 24612 24499.33333 chr1 24683 24850 24540.66667 chr1 24921 25011 24512 chr1 25055 25291 25339.75 chr1 25403 25740 25455.8 chr1 25767 25867 25403 chr1 26053 26153 25640 chr1 26406 26506 26791 chr1 26680 26883 26945.25 chr1 27102 27252 26710.33333 chr1 27582 27785 28041.5 chr1 27995 28187 27905.33333 chr1 28198 28298 28577 chr1 28439 28545 28031 chr1 28577 28674 28198 chr1 28679 28808 29090 chr1 29089 29191 28693.5 chr1 29331 29431 29686 chr1 29686 29786 29331 chr1 30409 30509 30809 chr1 30809 30909 30409 chr1 31781 31881 32173 chr1 32173 32273 31781 chr1 32519 32619 32926 chr1 32732 32832 33143 chr1 32926 33120 32984 chr1 33143 33289 33150.5 chr1 33449 33669 33396.33333 chr1 33842 33931 34268 chr1 33933 34044 33920 chr1 34070 34162 34511 chr1 34268 34451 33893 chr1 34511 34606 34070 chr1 35413 35513 35792 chr1 35792 35892 35413 chr1 36101 36201 36530.5 chr1 36528 36625 36101.5 chr1 37129 37229 37516 chr1 37516 37616 37129 chr1 37904 37996 38283 chr1 38283 38380 37904 chr1 38609 38709 38980 chr1 38980 39088 39013.5 chr1 39099 39199 39488 chr1 39418 39585 39335.66667 chr1 39920 40020 39528 chr1 43646 43746 44085 chr1 43974 44074 44404 chr1 44085 44185 43646 chr1 44304 44504 44331 chr1 44688 44788 44304 chr1 45372 45472 45738 chr1 45738 45867 45865 chr1 46111 46212 45756.5 chr1 47250 47346 47593 chr1 47593 47693 47250 chr1 47820 47920 48088 chr1 48088 48193 48149 chr1 48445 48677 48630.66667 chr1 48681 48781 49092 chr1 48832 48932 48445 chr1 48967 49067 48577 chr1 49092 49192 48681 chr1 10003 10143 chr1,chr1 chr1 10358 10428 chr10 chr1 11780 11921 chr1,chr1 chr1 11996 12101 chr1,chr1 chr1 12136 12347 chr1,chr1,chr1,chr1 chr1 12400 12503 chr1,chr1 chr1 12635 12779 chr1,chr1,chr1 chr1 12819 12919 chr1 chr1 13039 13139 chr1 chr1 13165 13287 chr1,chr1 chr1 13561 13731 chr1,chr1 chr1 14025 14125 chr1 chr1 14221 14340 chr1,chr1 chr1 14440 14715 chr1,chr1,chr1,chr1,chr1,chr1 chr1 14805 15172 chr1,chr1,chr1,chr1,chr1,chr1,chr1 chr1 15250 15350 chr1 chr1 15470 15603 chr1,chr1 chr1 15924 16065 chr1,chr1 chr1 16155 16255 chr1 chr1 16314 16438 chr1,chr1 chr1 16561 16661 chr1 chr1 16945 17038 chr1 chr1 17372 17472 chr1 chr1 17525 17625 chr1 chr1 17634 17734 chr1 chr1 17908 18008 chr1 chr1 18033 18133 chr1 chr1 18152 18252 chr1 chr1 18264 18364 chr1 chr1 18577 18742 chr1,chr1 chr1 19658 19758 chr1 chr1 19819 19966 chr1,chr1 chr1 20059 20320 chr1,chr1,chr1,chr1,chr1,chr1 chr1 20457 20627 chr1,chr1,chr1 chr1 20641 20741 chr1 chr1 20754 20854 chr1 chr1 21047 21139 chr1 chr1 21177 21277 chr1 chr1 21449 21549 chr1 chr1 21834 22029 chr1,chr1,chr1,chr1 chr1 22061 22149 chr1 chr1 22242 22448 chr1,chr1,chr1,chr1,chr1 chr1 22512 22566 chr1 chr1 22748 22848 chr1 chr1 22870 22970 chr1 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# chr1 1153667 1219633 f 6 + # chr1 1155173 1200334 g 7 - # chr1 1229798 1500664 h 8 - # chr1 1297735 1357056 i 9 + # chr1 1844181 1931789 j 10 - ########################################################### # basic cluster. ########################################################### echo -e " cluster.t1...\c" echo \ "chr1 72017 884436 a 1 + 1 chr1 72017 844113 b 2 + 1 chr1 939517 1011278 c 3 + 2 chr1 1142976 1203168 d 4 + 3 chr1 1153667 1298845 e 5 - 3 chr1 1153667 1219633 f 6 + 3 chr1 1155173 1200334 g 7 - 3 chr1 1229798 1500664 h 8 - 3 chr1 1297735 1357056 i 9 + 3 chr1 1844181 1931789 j 10 - 4" > exp $BT cluster -i in.bed > obs check obs exp rm obs exp ########################################################### # stranded cluster. ########################################################### echo -e " cluster.t2...\c" echo \ "chr1 72017 884436 a 1 + 1 chr1 72017 844113 b 2 + 1 chr1 939517 1011278 c 3 + 2 chr1 1142976 1203168 d 4 + 3 chr1 1153667 1219633 f 6 + 3 chr1 1297735 1357056 i 9 + 4 chr1 1153667 1298845 e 5 - 5 chr1 1155173 1200334 g 7 - 5 chr1 1229798 1500664 h 8 - 5 chr1 1844181 1931789 j 10 - 6" > exp $BT cluster -i in.bed -s > obs check obs exp rm obs exp [[ $FAILURES -eq 0 ]] || exit 1; chr1 72017 884436 a 1 + chr1 72017 844113 b 2 + chr1 939517 1011278 c 3 + chr1 1142976 1203168 d 4 + chr1 1153667 1298845 e 5 - chr1 1153667 1219633 f 6 + chr1 1155173 1200334 g 7 - chr1 1229798 1500664 h 8 - chr1 1297735 1357056 i 9 + chr1 1844181 1931789 j 10 - chr1 1000 chr1 100 200 a1 1 + chr1 100 200 a2 2 - set -e; BT=${BT-../../bin/bedtools} FAILURES=0; check() { if diff $1 $2; then echo ok else FAILURES=$(expr $FAILURES + 1); echo fail fi } # cat a.bed # chr1 100 200 a1 1 + # chr1 100 200 a2 2 - ########################################################### # test matching flanks via -b ########################################################### echo -e " slop.t1...\c" echo \ "chr1 95 205 a1 1 + chr1 95 205 a2 2 -" > exp $BT slop -i a.bed -b 5 -g tiny.genome > obs check obs exp rm obs exp ########################################################### # test matching flanks via -l and -r ########################################################### echo -e " slop.t2...\c" echo \ "chr1 95 205 a1 1 + chr1 95 205 a2 2 -" > exp > exp $BT slop -i a.bed -l 5 -r 5 -g tiny.genome > obs check obs exp rm obs exp ########################################################### # test just a -l flank (-r == 0) ########################################################### echo -e " slop.t3...\c" echo \ "chr1 95 200 a1 1 + chr1 95 200 a2 2 -" > exp $BT slop -i a.bed -l 5 -r 0 -g tiny.genome > obs check obs exp rm obs exp ########################################################### # test just a -r flank (-l == 0) ########################################################### echo -e " slop.t4...\c" echo \ "chr1 100 205 a1 1 + chr1 100 205 a2 2 -" > exp $BT slop -i a.bed -l 0 -r 5 -g tiny.genome > obs check obs exp rm obs exp ########################################################### # test just a -l flank (-r == 0) with -s ########################################################### echo -e " slop.t5...\c" echo \ "chr1 95 200 a1 1 + chr1 100 205 a2 2 -" > exp $BT slop -i a.bed -l 5 -r 0 -s -g tiny.genome > obs check obs exp rm obs exp ########################################################### # test just a -r flank (-l == 0) with -s ########################################################### echo -e " slop.t6...\c" echo \ "chr1 100 205 a1 1 + chr1 95 200 a2 2 -" > exp $BT slop -i a.bed -l 0 -r 5 -s -g tiny.genome > obs check obs exp rm obs exp ########################################################### # test -b with -s ########################################################### echo -e " slop.t7...\c" echo \ "chr1 95 205 a1 1 + chr1 95 205 a2 2 -" > exp $BT slop -i a.bed -b 5 -s -g tiny.genome > obs check obs exp rm obs exp ########################################################### # test going beyond the start of the chrom ########################################################### echo -e " slop.t8...\c" echo \ "chr1 0 400 a1 1 + chr1 0 400 a2 2 -" > exp $BT slop -i a.bed -b 200 -g tiny.genome > obs check obs exp rm obs exp ########################################################### # test going beyond the end of the chrom ########################################################### echo -e " slop.t9...\c" echo \ "chr1 100 1000 a1 1 + chr1 100 1000 a2 2 -" > exp $BT slop -i a.bed -l 0 -r 1000 -g tiny.genome > obs check obs exp rm obs exp ########################################################### # test going beyond the start and end of the chrom ########################################################### echo -e " slop.t10...\c" echo \ "chr1 0 1000 a1 1 + chr1 0 1000 a2 2 -" > exp $BT slop -i a.bed -b 2000 -g tiny.genome > obs check obs exp rm obs exp ########################################################### # test going beyond the start and end of the chrom with -s ########################################################### echo -e " slop.t11...\c" echo \ "chr1 0 1000 a1 1 + chr1 0 1000 a2 2 -" > exp $BT slop -i a.bed -b 2000 -s -g tiny.genome > obs check obs exp rm obs exp ########################################################### # test slop factor being larger than a signed int ########################################################### echo -e " slop.t12...\c" echo \ "chr1 0 1000 a1 1 + chr1 0 1000 a2 2 -" > exp $BT slop -i a.bed -b 3000000000 -s -g tiny.genome > obs check obs exp rm obs exp ########################################################### # test that old floating-point issues are solved ########################################################### echo -e " slop.t13...\c" echo \ "chr1 16778071 16778771" > exp echo -e "chr1\t16778271\t16778571"| $BT slop -l 200 -r 200 -i - -g ../../genomes/human.hg19.genome > obs check obs exp rm obs exp ########################################################### # test that old floating-point issues are solved ########################################################### echo -e " slop.t14...\c" echo \ "chr1 16778072 16778772" > exp echo -e "chr1\t16778272\t16778572"| $BT slop -l 200 -r 200 -i - -g ../../genomes/human.hg19.genome > obs check obs exp rm obs exp echo -e " slop.t15...\c" echo \ "chr1 159 171 chr1 90 210" > exp echo -e "chr1\t160\t170\nchr1\t100\t200"| $BT slop -b 0.1 -pct -i - -g ../../genomes/human.hg19.genome > obs check obs exp rm obs exp ########################################################### # test negative slop on l with strand ########################################################### echo -e " slop.t16...\c" echo \ "chr1 360 380" > exp echo -e "chr1\t300\t320" | $BT slop -l -60 -r 60 -i - -g tiny.genome > obs check obs exp rm obs exp echo -e " slop.t17...\c" echo \ "chr1 240 260 a1 5 -" > exp echo -e "chr1\t300\t320\ta1\t5\t-" | $BT slop -s -l -60 -r 60 -i - -g tiny.genome > obs check obs exp rm obs exp ########################################################### # test negative slop on r with strand ########################################################### echo -e " slop.t18...\c" echo \ "chr1 240 260" > exp echo -e "chr1\t300\t320" | $BT slop -l 60 -r -60 -i - -g tiny.genome > obs check obs exp rm obs exp echo -e " slop.t19...\c" echo \ "chr1 360 380 a1 5 -" > exp echo -e "chr1\t300\t320\ta1\t5\t-" | $BT slop -s -l 60 -r -60 -i - -g tiny.genome > obs check obs exp rm obs exp ########################################################### # test crossover during negative slop ########################################################### echo -e " slop.t20...\c" echo \ "chr1 260 360 a1 5 -" > exp echo -e "chr1\t300\t320\ta1\t5\t-" | $BT slop -s -l -60 -r -60 -i - -g tiny.genome > obs check obs exp rm obs exp ########################################################### # test edge cases ########################################################### echo -e " slop.t21...\c" echo \ "chr1 999 1000 a1 5 -" > exp echo -e "chr1\t950\t970\ta1\t5\t-" | $BT slop -s -l 60 -r -60 -i - -g tiny.genome > obs check obs exp rm obs exp echo -e " slop.t22...\c" echo \ "chr1 0 1 a1 5 -" > exp echo -e "chr1\t50\t60\ta1\t5\t-" | $BT slop -s -l -60 -r 60 -i - -g tiny.genome > obs check obs exp rm obs exp [[ $FAILURES -eq 0 ]] || exit 1; set -e; ########################################################### # # Unit tests for sampleFile program # ############################################################ BT=${BT-../../bin/bedtools} FAILURES=0; check() { if diff $1 $2; then echo ok else FAILURES=$(expr $FAILURES + 1); echo fail fi } ########################################################### # # Create a 1,000 record BED6 file named "mainFile.bed". # Give it a one line header, to test the -header option. # ########################################################### echo "#This is the mainFile from which samples will be taken." > mainFile.bed $BT random -l 1000 -n 1000 -g human.hg19.genome >> mainFile.bed ########################################################### # Test that help is printed when no args are given ############################################################ echo -e " sample.t01...\c" echo \ "***** ERROR: No input file given. Exiting. *****" > exp $BT sample 2>&1 > /dev/null | tail -1 > obs check obs exp rm obs ########################################################### # Test that we throw an error for unrecognized arguments ############################################################ echo -e " sample.new.t02...\c" echo "***** ERROR: Unrecognized parameter: -wrongArg *****" > exp $BT sample -i mainFile.bed -wrongArg 2>&1 > /dev/null | tail -1 > obs check obs exp rm obs exp ########################################################### # Test that we throw an error when no input file was given. ############################################################ echo -e " sample.new.t03...\c" echo "***** ERROR: No input file given. Exiting. *****" > exp; $BT sample -n 10 2>&1 > /dev/null | tail -1 > obs check obs exp rm obs exp ########################################################### # Test that we throw an error for -i without input file ############################################################ echo -e " sample.new.t04...\c" echo "***** ERROR: -i option given, but no input file specified. *****" > exp $BT sample -i 2>&1 > /dev/null | tail -1 > obs check obs exp rm obs exp ########################################################### # Test that we throw an error for -n given without # number of output records sepcified. ############################################################ echo -e " sample.new.t05...\c" echo "***** ERROR: -n option given, but no number of output records specified. *****" > exp $BT sample -n 2>&1 > /dev/null | tail -1 > obs check obs exp rm obs exp ########################################################### # Test that we throw an error when num output records # exceeds records in file. ############################################################ echo -e " sample.new.t06...\c" echo "***** ERROR: Input file has fewer records than the requested number of output records. *****" > exp $BT sample -i mainFile.bed 2>&1 > /dev/null | head -2 | tail -1 > obs check obs exp rm obs exp ########################################################### # Test that we get the requested number of records ############################################################ echo -e " sample.new.t07...\c" echo "10" > exp # BSD wc adds leading whitespace, and BSD sed -i param requires extension $BT sample -i mainFile.bed -n 10 | wc -l | sed 's/^[ \t]*//' > obs check obs exp rm obs exp ########################################################### # Test that the -seed option gives consistent results ############################################################ echo -e " sample.new.t08...\c" $BT sample -i mainFile.bed -n 50 -seed 4 > obs $BT sample -i mainFile.bed -n 50 -seed 4 > exp check obs exp rm obs exp ########################################################### # Test that -header option gives header ############################################################ echo -e " sample.new.t09...\c" echo "#This is the mainFile from which samples will be taken." > exp $BT sample -i mainFile.bed -n 10 -header | head -1 > obs check obs exp rm obs exp rm mainFile.bed [[ $FAILURES -eq 0 ]] || exit 1; chr1 249250621 chr10 135534747 chr11 135006516 chr11_gl000202_random 40103 chr12 133851895 chr13 115169878 chr14 107349540 chr15 102531392 chr16 90354753 chr17 81195210 chr17_ctg5_hap1 1680828 chr17_gl000203_random 37498 chr17_gl000204_random 81310 chr17_gl000205_random 174588 chr17_gl000206_random 41001 chr18 78077248 chr18_gl000207_random 4262 chr19 59128983 chr19_gl000208_random 92689 chr19_gl000209_random 159169 chr1_gl000191_random 106433 chr1_gl000192_random 547496 chr2 243199373 chr20 63025520 chr21 48129895 chr21_gl000210_random 27682 chr22 51304566 chr3 198022430 chr4 191154276 chr4_ctg9_hap1 590426 chr4_gl000193_random 189789 chr4_gl000194_random 191469 chr5 180915260 chr6 171115067 chr6_apd_hap1 4622290 chr6_cox_hap2 4795371 chr6_dbb_hap3 4610396 chr6_mann_hap4 4683263 chr6_mcf_hap5 4833398 chr6_qbl_hap6 4611984 chr6_ssto_hap7 4928567 chr7 159138663 chr7_gl000195_random 182896 chr8 146364022 chr8_gl000196_random 38914 chr8_gl000197_random 37175 chr9 141213431 chr9_gl000198_random 90085 chr9_gl000199_random 169874 chr9_gl000200_random 187035 chr9_gl000201_random 36148 chrM 16571 chrUn_gl000211 166566 chrUn_gl000212 186858 chrUn_gl000213 164239 chrUn_gl000214 137718 chrUn_gl000215 172545 chrUn_gl000216 172294 chrUn_gl000217 172149 chrUn_gl000218 161147 chrUn_gl000219 179198 chrUn_gl000220 161802 chrUn_gl000221 155397 chrUn_gl000222 186861 chrUn_gl000223 180455 chrUn_gl000224 179693 chrUn_gl000225 211173 chrUn_gl000226 15008 chrUn_gl000227 128374 chrUn_gl000228 129120 chrUn_gl000229 19913 chrUn_gl000230 43691 chrUn_gl000231 27386 chrUn_gl000232 40652 chrUn_gl000233 45941 chrUn_gl000234 40531 chrUn_gl000235 34474 chrUn_gl000236 41934 chrUn_gl000237 45867 chrUn_gl000238 39939 chrUn_gl000239 33824 chrUn_gl000240 41933 chrUn_gl000241 42152 chrUn_gl000242 43523 chrUn_gl000243 43341 chrUn_gl000244 39929 chrUn_gl000245 36651 chrUn_gl000246 38154 chrUn_gl000247 36422 chrUn_gl000248 39786 chrUn_gl000249 38502 chrX 155270560 chrY 59373566 chrbig 5000000000 5000000060 chr1 1 10 chr1 9 8000000000 chr1 8000000000 9000000000 set -e; BT=${BT-../../bin/bedtools} FAILURES=0; check() { if diff $1 $2; then echo ok else FAILURES=$(expr $FAILURES + 1); echo fail fi } ########################################################### # Test a basic self intersection ############################################################ echo -e " bigchroms.t01...\c" $BT intersect -sorted -a abig.bed -b abig.bed > obs check obs abig.bed rm obs echo -e " bigchroms.t02...\c" $BT intersect -a abig.bed -b abig.bed > obs check obs abig.bed rm obs if [[ "$BT_NO_BIG_FILES" != "" ]]; then python make-big-chrom.py echo -e " bigchroms.t03...big get fasta \c" $BT getfasta -fi bigx.fasta -bed bigx.bed | tail -1 > obs echo "ACTGACCCCGAGACGTTTGCATCCTGCACAGCTAGAGATCCTTTATTAAAAGCACACTGT" > exp check obs exp rm obs exp rm bigx.fasta* else echo -e " bigchroms.t03... skip \c" echo " set env var 'BT_NO_BIG_FILES' to run this test" fi echo -e " bigchroms.t04... merge \c" echo "chr1 1 9000000000" > exp $BT merge -i big4.bed > obs check obs exp rm obs exp echo -e " bigchroms.t05... closest \c" $BT closest -a big4c.bed -b big4.bed > obs echo "chr1 1 10 chr1 1 10 chr1 1 10 chr1 9 8000000000 chr1 8900000000 9000000000 chr1 8000000000 9000000000" > exp check obs exp rm obs exp [[ $FAILURES -eq 0 ]] || exit 1; chr1 1 10 chr1 8900000000 9000000000 import sys try: xrange except: xrange = range size = 5000000000 linelen = 200 extra = "ACTGACCCCGAGACGTTTGCATCCTGCACAGCTAGAGATCCTTTATTAAAAGCACACTGT" with open("bigx.fasta", "wb") as fh: fh.write(">chrbig\n") line = ("N" * linelen) + "\n" for i in xrange(0, size, len(line) - 1): fh.write(line) fh.write(extra + "\n") fh.close() with open("bigx.fasta.fai", "wb") as fh: fh.write("chrbig\t%d\t8\t%d\t%d\n" % (size + len(extra), linelen, linelen+1)) 1 123 30000000000 set -e; BT=${BT-../../bin/bedtools} FAILURES=0; check() { if diff $1 $2; then echo ok else FAILURES=$(expr $FAILURES + 1); echo fail fi } # Tools that are expected to fail should exit non-zero. If they don't, that is a # failure. failedtofail() { FAILURES=$(expr $FAILURES + 1); echo "Expected non-zero exit status but didn't get one"; } ########################################################### # Enforce non-negative coordinates ########################################################### echo -e " general.t01...\c" echo \ "chr1 1 10 chr1 -1 10" | $BT merge -i - 2> obs \ && failedtofail || true; echo "Error: Invalid record in file -. Record is chr1 -1 10" > exp check obs exp rm obs exp ########################################################### # Enforce start <= end ########################################################### echo -e " general.t02...\c" echo \ "chr1 1 2 chr1 10 5" | $BT merge -i - 2> obs \ && failedtofail || true; echo "Error: Invalid record in file -. Record is chr1 10 5" > exp check obs exp rm obs exp ########################################################### # Enforce integer coordinates ########################################################### echo -e " general.t03...\c" echo "Error: unable to open file or unable to determine types for file - - Please ensure that your file is TAB delimited (e.g., cat -t FILE). - Also ensure that your file has integer chromosome coordinates in the expected columns (e.g., cols 2 and 3 for BED)." >> exp #echo "ERROR: file - has non positional records, which are only valid for " >> exp #echo " the groupBy tool. Perhaps you are using a header line(s) that starts with " >> exp #echo " something other than \"#\", \"chrom\", or \"chr\" (any case)?" >> exp echo "chr1 . 2" | $BT merge -i - 2> o \ && failedtofail || true; tail -n 5 o > obs check obs exp rm o obs exp ########################################################### # Enforce tab-separated files ########################################################### echo -e " general.t05...\c" echo \ "chr1 1 2" | $BT merge -i - 2> o \ && failedtofail || true; echo "Error: unable to open file or unable to determine types for file - - Please ensure that your file is TAB delimited (e.g., cat -t FILE). - Also ensure that your file has integer chromosome coordinates in the expected columns (e.g., cols 2 and 3 for BED)." >> exp tail -n 5 o > obs check obs exp rm o obs exp ########################################################### # Fail on non-existent files. ########################################################### echo -e " general.t06...\c" $BT merge -i idontexist.bed 2> obs \ && failedtofail || true; echo "Error: Unable to open file idontexist.bed. Exiting." > exp check obs exp rm obs exp ########################################################### # Don't fail on existent, yet empty files. ########################################################### echo -e " general.t07...\c" $BT merge -i empty.bed 2> obs touch exp check obs exp rm obs exp ########################################################### # Process gzipped files. ########################################################### echo -e " general.t08...\c" $BT merge -i non-empty.bed.gz > obs echo "chr1 10 21" > exp check obs exp rm obs exp ########################################################### # Test GZIP, non-GZIP, and empty file functionality. ########################################################### echo "chr1 1 100" > a.bed echo "chr1 75 200" > b.bed echo -n "" > c.bed echo "chr1 1 5000" > genome.txt gzip -c a.bed > a.bed.gz gzip -c b.bed > b.bed.gz gzip -c c.bed > c.bed.gz echo -e " general.t09...\c" $BT intersect -a a.bed -b b.bed > obs echo "chr1 75 100" > exp check obs exp echo -e " general.t10...\c" $BT intersect -a a.bed.gz -b b.bed.gz > obs echo "chr1 75 100" > exp check obs exp echo -e " general.t11...\c" $BT intersect -a a.bed -b b.bed.gz > obs echo "chr1 75 100" > exp check obs exp echo -e " general.t12...\c" $BT intersect -a a.bed.gz -b b.bed > obs echo "chr1 75 100" > exp check obs exp echo -e " general.t13...\c" $BT intersect -a c.bed -b b.bed > obs echo -n "" > exp check obs exp echo -e " general.t14...\c" $BT intersect -a c.bed.gz -b b.bed > obs echo -n "" > exp check obs exp echo -e " general.15...\c" $BT intersect -a c.bed.gz -b c.bed.gz > obs echo -n "" > exp check obs exp echo -e " general.t16...\c" $BT subtract -a a.bed -b b.bed > obs echo "chr1 1 75" > exp check obs exp echo -e " general.t17...\c" $BT subtract -a a.bed.gz -b b.bed.gz > obs echo "chr1 1 75" > exp check obs exp echo -e " general.t18...\c" $BT subtract -a a.bed -b b.bed.gz > obs echo "chr1 1 75" > exp check obs exp echo -e " general.t19...\c" $BT subtract -a a.bed.gz -b b.bed > obs echo "chr1 1 75" > exp check obs exp echo -e " general.t20...\c" $BT subtract -a c.bed -b b.bed > obs echo -n "" > exp check obs exp echo -e " general.t21...\c" $BT subtract -a c.bed.gz -b b.bed > obs echo -n "" > exp check obs exp echo -e " general.22...\c" $BT subtract -a c.bed.gz -b c.bed.gz > obs echo -n "" > exp check obs exp echo -e " general.t23...\c" $BT window -a a.bed -b b.bed > obs echo "chr1 1 100 chr1 75 200" > exp check obs exp echo -e " general.t24...\c" $BT window -a a.bed.gz -b b.bed.gz > obs echo "chr1 1 100 chr1 75 200" > exp check obs exp echo -e " general.t25...\c" $BT window -a a.bed -b b.bed.gz > obs echo "chr1 1 100 chr1 75 200" > exp check obs exp echo -e " general.t26...\c" $BT window -a a.bed.gz -b b.bed > obs echo "chr1 1 100 chr1 75 200" > exp check obs exp echo -e " general.t27...\c" $BT window -a c.bed -b b.bed > obs echo -n "" > exp check obs exp echo -e " general.t28...\c" $BT window -a c.bed.gz -b b.bed > obs echo -n "" > exp check obs exp echo -e " general.29...\c" $BT window -a c.bed.gz -b c.bed.gz > obs echo -n "" > exp check obs exp echo -e " general.t30...\c" $BT closest -a a.bed -b b.bed > obs echo "chr1 1 100 chr1 75 200" > exp check obs exp echo -e " general.t31...\c" $BT closest -a a.bed.gz -b b.bed.gz > obs echo "chr1 1 100 chr1 75 200" > exp check obs exp echo -e " general.t32...\c" $BT closest -a a.bed -b b.bed.gz > obs echo "chr1 1 100 chr1 75 200" > exp check obs exp echo -e " general.t33...\c" $BT closest -a a.bed.gz -b b.bed > obs echo "chr1 1 100 chr1 75 200" > exp check obs exp echo -e " general.t34...\c" $BT closest -a c.bed -b b.bed > obs echo -n "" > exp check obs exp echo -e " general.t35...\c" $BT closest -a c.bed.gz -b b.bed > obs echo -n "" > exp check obs exp echo -e " general.36...\c" $BT closest -a c.bed.gz -b c.bed.gz > obs echo -n "" > exp check obs exp echo -e " general.t37...\c" $BT merge -i a.bed > obs echo "chr1 1 100" > exp check obs exp echo -e " general.t38...\c" $BT merge -i a.bed.gz > obs echo "chr1 1 100" > exp check obs exp echo -e " general.t39...\c" $BT merge -i b.bed > obs echo "chr1 75 200" > exp check obs exp echo -e " general.t40...\c" $BT merge -i b.bed.gz > obs echo "chr1 75 200" > exp check obs exp echo -e " general.t41...\c" $BT merge -i c.bed > obs echo -n "" > exp check obs exp echo -e " general.t42...\c" $BT merge -i c.bed.gz > obs echo -n "" > exp check obs exp # allow header lines to start with chr or chrom echo -e " general.t43...\c" echo "chrom chromStart chromEnd name score strand chr14 24800000 24810000 blarg 0 . chr11 64610000 64620000 blarg 0 . chr14 24710000 24720000 blarg 0 . chr11 111230000 111240000 blarg 0 ." > exp $BT intersect -a t.bed -b t.bed -header > obs check obs exp echo -e " general.t44...\c" $BT intersect -a a.bed.gz -b b.bed -g hg19.fa.fai > obs echo "chr1 75 100" > exp check obs exp # allow header lines to start with chrom or track echo -e " general.t45...\c" echo "chr1 15 20" > exp $BT intersect -a a.trackheader.bed -b a.chromheader.bed > obs check obs exp # allow header lines to start with chrom or track echo -e " general.t46...\c" echo "track chr1 15 20" > exp $BT intersect -a a.trackheader.bed -b a.chromheader.bed -header > obs check obs exp rm a.bed.gz b.bed.gz c.bed.gz a.bed b.bed c.bed genome.txt exp obs [[ $FAILURES -eq 0 ]] || exit 1; chrom start end chr1 15 25 track chr1 10 20 chr1 249250621 6 50 51 Pnon-empty.bedK(24442J3 9 0chrom chromStart chromEnd name score strand chr14 24800000 24810000 blarg 0 . chr11 64610000 64620000 blarg 0 . chr14 24710000 24720000 blarg 0 . chr11 111230000 111240000 blarg 0 . chrX 840 40278 chrX 783 80627 chrX 911 20666 chrX 335 77157 chrX 277 55673 chrX 477 63364 chrX 364 51704 chrX 952 92571 chrX 635 72364 chrX 141 60837 chrX 16 24304 chrX 137 80554 chrX 156 40250 chrX 129 11009 chrX 998 22823 chrX 512 84423 chrX 612 30215 chrX 637 53065 chrX 493 97770 chrX 292 77427 chrX 526 77517 chrX 400 89552 chrX 283 35528 chrX 807 92709 chrX 69 95001 chrX 525 9130 chrX 192 66514 chrX 890 35779 chrX 64 2066 chrX 457 6766 chrX 238 97301 chrX 902 85993 chrX 266 54242 chrX 375 76399 chrX 512 67284 chrX 531 4459 chrX 437 93620 chrX 930 73025 chrX 284 74137 chrX 639 36043 chrX 687 17284 chrX 440 88447 chrX 829 33862 chrX 228 89565 chrX 350 69016 chrX 956 59820 chrX 657 86524 chrX 439 92835 chrX 398 81874 chrX 684 91781 chrX 482 22064 chrX 950 92962 chrX 147 88253 chrX 641 43836 chrX 619 28724 chrX 786 31531 chrX 447 23057 chrX 187 27810 chrX 556 42206 chrX 169 90849 chrX 103 12710 chrX 495 76542 chrX 984 94484 chrX 684 39002 chrX 749 37615 chrX 294 23520 chrX 584 25025 chrX 152 73366 chrX 125 79472 chrX 164 74671 chrX 74 95084 chrX 52 52208 chrX 176 24182 chrX 797 74062 chrX 656 97396 chrX 639 76612 chrX 93 13583 chrX 520 8343 chrX 69 20534 chrX 461 82428 chrX 573 76131 chrX 51 15831 chrX 999 21431 chrX 889 13435 chrX 997 6402 chrX 870 8102 chrX 4 92310 chrX 593 18630 chrX 163 39332 chrX 913 82882 chrX 359 55607 chrX 579 45836 chrX 687 10651 chrX 530 76259 chrX 304 99526 chrX 576 88337 chrX 747 63637 chrX 35 74815 chrX 833 93370 chrX 873 83976 chrX 979 75360 chrX 903 99262 chrX 666 50391 chrX 163 83164 chrX 888 8587 chrX 649 25453 chrX 629 23542 chrX 700 32386 chrX 328 23470 chrX 74 63381 chrX 223 65336 chrX 510 97656 chrX 280 54890 chrX 719 12047 chrX 471 59724 chrX 944 46035 chrX 336 85104 chrX 434 757 chrX 344 60192 chrX 833 24222 chrX 675 48970 chrX 481 30976 chrX 712 18967 chrX 621 4707 chrX 413 70011 chrX 673 64437 chrX 347 18809 chrX 609 63324 chrX 730 33567 chrX 740 20961 chrX 920 69395 chrX 653 26379 chrX 532 9296 chrX 260 87998 chrX 686 10060 chrX 111 36271 chrX 576 59897 chrX 666 29543 chrX 775 29612 chrX 329 19304 chrX 984 1341 chrX 827 33974 chrX 188 43837 chrX 958 92851 chrX 764 70671 chrX 121 68699 chrX 383 77810 chrX 943 92570 chrX 861 21215 chrX 793 55597 chrX 297 90790 chrX 909 88306 chrX 498 58117 chrX 162 27553 chrX 864 50103 chrX 463 85357 chrX 495 29600 chrX 180 68597 chrX 727 14632 chrX 603 49845 chrX 838 73263 chrX 178 22374 chrX 498 12623 chrX 138 36182 chrX 324 93513 chrX 908 63117 chrX 836 82648 chrX 496 33993 chrX 394 66277 chrX 608 26498 chrX 151 7405 chrX 107 64827 chrX 363 29189 chrX 331 9445 chrX 427 93876 chrX 583 27129 chrX 658 76835 chrX 487 16214 chrX 883 63449 chrX 517 21301 chrX 557 43176 chrX 829 40267 chrX 244 32845 chrX 729 64594 chrX 984 34808 chrX 897 14504 chrX 410 950 chrX 783 78221 chrX 293 11759 chrX 865 72965 chrX 49 44959 chrX 986 71776 chrX 210 47599 chrX 865 10256 chrX 99 38388 chrX 301 66012 chrX 809 13979 chrX 51 5393 chrX 457 78543 chrX 692 44948 chrX 119 59082 chrX 578 53567 chrX 595 36786 chrX 304 89176 chrX 476 17458 chrX 609 53183 chrX 618 60237 chrX 233 83213 chrX 70 9953 chrX 923 17887 chrX 481 23030 chrX 826 29908 chrX 357 88184 chrX 344 81834 chrX 659 4291 chrX 257 78082 chrX 625 84235 chrX 308 22408 chrX 198 61442 chrX 109 67569 chrX 782 72728 chrX 200 40318 chrX 315 43715 chrX 230 38804 chrX 532 16004 chrX 555 2012 chrX 380 38596 chrX 305 74045 chrX 260 65225 chrX 552 92511 chrX 685 81663 chrX 697 31892 chrX 645 1245 chrX 532 84922 chrX 618 64887 chrX 518 40588 chrX 362 72248 chrX 801 68582 chrX 152 3441 chrX 63 68635 chrX 187 62082 chrX 700 57483 chrX 1 571 chrX 305 26462 chrX 655 86410 chrX 181 34316 chrX 667 88567 chrX 653 31975 chrX 885 19511 chrX 157 50503 chrX 828 68393 chrX 904 20015 chrX 394 71000 chrX 868 55607 chrX 738 93986 chrX 233 92890 chrX 551 93893 chrX 494 55750 chrX 939 80903 chrX 814 60263 chrX 657 100186 chrX 935 33389 chrX 874 59789 chrX 637 76569 chrX 775 80266 chrX 262 60699 chrX 470 17165 chrX 795 87303 chrX 873 67314 chrX 412 61610 chrX 596 65156 chrX 538 15372 chrX 579 3875 chrX 700 52515 chrX 832 52336 chrX 112 49093 chrX 510 5359 chrX 814 39279 chrX 637 45849 chrX 143 41450 chrX 247 40923 chrX 17 71776 chrX 573 81867 chrX 582 45256 chrX 477 99993 chrX 58 7484 chrX 640 60367 chrX 222 22200 chrX 630 92981 chrX 737 47022 chrX 438 85496 chrX 952 95843 chrX 899 77600 chrX 333 54007 chrX 219 47974 chrX 949 47565 chrX 884 97611 chrX 183 45986 chrX 780 77424 chrX 904 26662 chrX 761 97111 chrX 331 40568 chrX 560 56004 chrX 622 19724 chrX 477 36487 chrX 653 92305 chrX 210 60864 chrX 865 11842 chrX 373 20273 chrX 646 59915 chrX 676 60310 chrX 58 56145 chrX 563 24825 chrX 18 34402 chrX 9 92378 chrX 601 77669 chrX 887 94214 chrX 173 44971 chrX 487 80010 chrX 639 97207 chrX 155 29443 chrX 882 37484 chrX 899 75662 chrX 475 27773 chrX 946 13178 chrX 865 63184 chrX 718 93171 chrX 184 28412 chrX 167 20464 chrX 626 18249 chrX 126 22881 chrX 946 2332 chrX 160 12158 chrX 461 65315 chrX 915 11000 chrX 614 7669 chrX 393 50036 chrX 436 29753 chrX 244 91483 chrX 566 19636 chrX 34 43218 chrX 813 76151 chrX 356 100152 chrX 35 52389 chrX 200 66379 chrX 699 33460 chrX 889 65560 chrX 341 5357 chrX 766 81099 chrX 698 68890 chrX 904 32197 chrX 752 30545 chrX 809 19715 chrX 591 5934 chrX 101 15828 chrX 244 13861 chrX 589 6394 chrX 889 95439 chrX 56 92577 chrX 469 26165 chrX 587 17470 chrX 584 48219 chrX 815 93421 chrX 526 58751 chrX 729 23252 chrX 264 63622 chrX 538 2203 chrX 931 35685 chrX 205 52467 chrX 400 31116 chrX 679 65192 chrX 443 27345 chrX 703 33992 chrX 214 76134 chrX 258 68615 chrX 16 84528 chrX 852 60928 chrX 321 67117 chrX 526 85326 chrX 250 25872 chrX 73 51511 chrX 889 62030 chrX 531 82664 chrX 958 74632 chrX 343 36337 chrX 43 2429 chrX 5 48730 chrX 292 71118 chrX 820 51560 chrX 467 8292 chrX 190 48554 chrX 923 5262 chrX 84 24569 chrX 711 61835 chrX 92 96248 chrX 867 17476 chrX 475 76203 chrX 777 1475 chrX 578 74224 chrX 743 93000 chrX 96 78860 chrX 946 11094 chrX 274 24206 chrX 809 10313 chrX 746 28467 chrX 173 93944 chrX 760 10428 chrX 981 85508 chrX 341 69587 chrX 456 43895 chrX 654 33052 chrX 600 13597 chrX 81 37880 chrX 136 66123 chrX 114 88182 chrX 582 21668 chrX 668 53556 chrX 312 94634 chrX 768 12976 chrX 38 51531 chrX 399 21555 chrX 452 16468 chrX 308 43683 chrX 5 64983 chrX 126 46320 chrX 84 78109 chrX 785 69252 chrX 910 87629 chrX 62 4780 chrX 527 18240 chrX 927 11879 chrX 387 60006 chrX 638 70671 chrX 539 41200 chrX 822 58589 chrX 921 23093 chrX 789 38209 chrX 381 10130 chrX 807 39539 chrX 747 94165 chrX 849 83995 chrX 714 64234 chrX 516 62981 chrX 502 58383 chrX 671 3618 chrX 755 60725 chrX 139 14533 chrX 195 77936 chrX 844 74375 chrX 184 66854 chrX 312 10869 chrX 888 11111 chrX 479 27511 chrX 199 28972 chrX 657 95357 chrX 221 50912 chrX 778 94412 chrX 142 29602 chrX 561 65012 chrX 873 24157 chrX 673 63608 chrX 832 82131 chrX 773 3618 chrX 590 62348 chrX 763 78206 chrX 284 7959 chrX 880 18152 chrX 178 36156 chrX 443 38314 chrX 647 10715 chrX 325 87268 chrX 607 11024 chrX 805 75776 chrX 398 37077 chrX 394 27612 chrX 599 7422 chrX 901 44120 chrX 881 68365 chrX 460 47623 chrX 292 22733 chrX 246 57918 chrX 301 12908 chrX 749 48764 chrX 485 19733 chrX 858 14196 chrX 293 18750 chrX 2 90079 chrX 288 81149 chrX 650 69402 chrX 175 4647 chrX 959 78464 chrX 112 86238 chrX 207 99626 chrX 536 67326 chrX 465 83319 chrX 892 72082 chrX 405 19754 chrX 837 16308 chrX 673 33058 chrX 347 53598 chrX 457 64493 chrX 717 46723 chrX 541 1125 chrX 268 19431 chrX 693 45102 chrX 236 65544 chrX 219 35151 chrX 514 43155 chrX 343 5389 chrX 94 81029 chrX 879 99543 chrX 521 28948 chrX 180 36104 chrX 438 85816 chrX 683 79301 chrX 386 14419 chrX 426 10765 chrX 600 97369 chrX 109 87017 chrX 159 80419 chrX 313 39881 chrX 455 53689 chrX 745 97749 chrX 958 9810 chrX 20 5327 chrX 897 90849 chrX 39 41953 chrX 183 22168 chrX 778 63057 chrX 73 46221 chrX 408 46401 chrX 601 84154 chrX 563 20786 chrX 803 68059 chrX 71 96326 chrX 475 38925 chrX 358 93443 chrX 916 11240 chrX 900 88460 chrX 191 92331 chrX 928 9893 chrX 820 97659 chrX 508 980 chrX 188 28906 chrX 627 26815 chrX 748 4397 chrX 721 35771 chrX 872 29386 chrX 552 68077 chrX 957 63362 chrX 637 43924 chrX 8 99612 chrX 363 92904 chrX 99 26561 chrX 801 29906 chrX 186 73156 chrX 380 1075 chrX 698 89649 chrX 11 88645 chrX 176 64095 chrX 148 92685 chrX 675 87680 chrX 275 55047 chrX 155 83017 chrX 222 11513 chrX 452 86530 chrX 545 46669 chrX 856 91807 chrX 386 95997 chrX 174 18943 chrX 247 36263 chrX 917 63704 chrX 367 61916 chrX 517 38396 chrX 501 69910 chrX 17 65023 chrX 619 69988 chrX 520 90055 chrX 241 67773 chrX 723 47162 chrX 788 18453 chrX 325 33726 chrX 637 18837 chrX 243 2700 chrX 138 41904 chrX 212 38740 chrX 777 13743 chrX 13 14507 chrX 745 53800 chrX 523 25221 chrX 224 54398 chrX 897 85308 chrX 235 41952 chrX 739 48424 chrX 92 46436 chrX 941 89013 chrX 640 27281 chrX 214 28014 chrX 448 46274 chrX 302 58955 chrX 875 52359 chrX 971 66346 chrX 644 99141 chrX 798 39764 chrX 515 32760 chrX 636 74653 chrX 864 54235 chrX 584 10546 chrX 950 33325 chrX 576 4913 chrX 787 52559 chrX 924 43653 chrX 784 14668 chrX 705 23961 chrX 597 1385 chrX 819 48123 chrX 522 79613 chrX 126 16850 chrX 775 93326 chrX 556 29699 chrX 247 19603 chrX 31 11246 chrX 727 62316 chrX 211 68027 chrX 939 79765 chrX 721 73405 chrX 305 64869 chrX 154 9166 chrX 784 86728 chrX 322 38482 chrX 867 15046 chrX 854 39859 chrX 932 99077 chrX 557 71418 chrX 906 12325 chrX 0 15492 chrX 307 3472 chrX 267 3770 chrX 647 48533 chrX 713 59432 chrX 267 43740 chrX 314 57626 chrX 80 46898 chrX 663 87150 chrX 327 98921 chrX 246 19740 chrX 127 10239 chrX 584 6629 chrX 82 14310 chrX 769 99723 chrX 256 77168 chrX 144 56569 chrX 800 41955 chrX 599 45431 chrX 890 32139 chrX 35 15790 chrX 747 35703 chrX 730 83491 chrX 817 40209 chrX 692 15229 chrX 379 94275 chrX 340 51101 chrX 40 92571 chrX 568 12834 chrX 67 33782 chrX 112 32521 chrX 106 25773 chrX 888 91592 chrX 668 49431 chrX 355 56219 chrX 800 39888 chrX 716 55451 chrX 740 45427 chrX 374 56193 chrX 840 7586 chrX 703 22770 chrX 6 4395 chrX 728 5379 chrX 969 30606 chrX 169 3850 chrX 633 28771 chrX 360 74339 chrX 538 25464 chrX 646 21273 chrX 736 956 chrX 764 54467 chrX 393 48505 chrX 84 13438 chrX 928 46864 chrX 691 77571 chrX 526 40057 chrX 989 54314 chrX 439 72216 chrX 579 41420 chrX 14 74908 chrX 445 65212 chrX 30 80644 chrX 387 57224 chrX 55 3485 chrX 774 80005 chrX 36 53994 chrX 329 43290 chrX 20 41393 chrX 563 95433 chrX 873 26363 chrX 717 40709 chrX 650 71349 chrX 933 9875 chrX 424 51718 chrX 497 44389 chrX 261 94569 chrX 86 29306 chrX 749 48155 chrX 860 81324 chrX 508 64032 chrX 596 55084 chrX 174 92803 chrX 974 20527 chrX 340 54105 chrX 144 21456 chrX 792 86967 chrX 613 44891 chrX 568 55190 chrX 532 99884 chrX 59 3065 chrX 432 32536 chrX 973 52877 chrX 613 72850 chrX 993 48377 chrX 527 50674 chrX 109 12505 chrX 46 28437 chrX 50 2136 chrX 479 39507 chrX 558 62928 chrX 603 35711 chrX 485 22130 chrX 793 6214 chrX 762 33371 chrX 47 82231 chrX 356 48375 chrX 142 33072 chrX 999 76613 chrX 51 99286 chrX 229 58099 chrX 493 34400 chrX 702 54721 chrX 622 75915 chrX 561 10805 chrX 143 12101 chrX 726 75389 chrX 470 21630 chrX 963 27418 chrX 265 72842 chrX 590 31946 chrX 547 95228 chrX 793 69843 chrX 276 79575 chrX 446 33226 chrX 785 68447 chrX 906 28823 chrX 15 60932 chrX 819 64687 chrX 362 38405 chrX 741 51274 chrX 500 47227 chrX 251 97320 chrX 678 22184 chrX 235 94704 chrX 940 83529 chrX 258 49102 chrX 772 5973 chrX 178 5060 chrX 845 63404 chrX 376 63411 chrX 302 28615 chrX 909 32701 chrX 892 73782 chrX 956 26399 chrX 109 69883 chrX 759 61694 chrX 165 1339 chrX 580 84969 chrX 226 81755 chrX 788 17552 chrX 641 5325 chrX 656 42045 chrX 98 83603 chrX 462 94848 chrX 460 84395 chrX 574 76861 chrX 122 48496 chrX 80 1560 chrX 212 3952 chrX 269 32467 chrX 735 3636 chrX 931 90947 chrX 40 51178 chrX 744 27500 chrX 326 53590 chrX 435 97221 chrX 579 9710 chrX 381 68216 chrX 926 85374 chrX 622 39323 chrX 683 20325 chrX 149 80781 chrX 680 23747 chrX 821 90102 chrX 268 9304 chrX 214 537 chrX 119 14732 chrX 903 16916 chrX 657 65401 chrX 427 98847 chrX 180 86471 chrX 952 76911 chrX 954 34337 chrX 437 88496 chrX 178 6193 chrX 267 86481 chrX 256 42004 chrX 668 94343 chrX 648 49607 chrX 829 92454 chrX 579 5015 chrX 919 70853 chrX 190 82477 chrX 859 85661 chrX 470 29188 chrX 832 65874 chrX 150 78579 chrX 410 10843 chrX 118 84913 chrX 984 30628 chrX 908 26161 chrX 158 16627 chrX 670 83375 chrX 101 31920 chrX 316 93417 chrX 234 89895 chrX 975 16367 chrX 595 17183 chrX 976 46520 chrX 13 44725 chrX 742 85354 chrX 97 89369 chrX 630 51385 chrX 997 75852 chrX 355 98552 chrX 44 26405 chrX 234 20591 chrX 428 90881 chrX 30 53005 chrX 222 34950 chrX 460 46177 chrX 243 43857 chrX 611 84597 chrX 602 59391 chrX 295 61888 chrX 35 3828 chrX 462 13717 chrX 930 10178 chrX 640 93410 chrX 841 100403 chrX 909 89512 chrX 259 14678 chrX 89 68843 chrX 48 12072 chrX 217 27363 chrX 467 68273 chrX 728 71871 chrX 114 34087 chrX 551 72175 chrX 927 85588 chrX 332 96595 chrX 884 80308 chrX 95 81614 chrX 886 74416 chrX 742 73519 chrX 730 65988 chrX 613 99629 chrX 796 71137 chrX 677 85229 chrX 823 90323 chrX 116 29234 chrX 573 85136 chrX 2 68731 chrX 185 55577 chrX 403 11701 chrX 400 73972 chrX 75 28582 chrX 529 17610 chrX 100 41770 chrX 906 85223 chrX 144 63849 chrX 495 76323 chrX 627 29882 chrX 461 30953 chrX 138 28674 chrX 199 25706 chrX 576 77877 chrX 100 58017 chrX 460 29067 chrX 133 86518 chrX 399 53762 chrX 599 48067 chrX 818 13772 chrX 645 92544 chrX 546 55709 chrX 762 69835 chrX 188 25981 chrX 449 82039 chrX 550 91622 chrX 120 68977 chrX 196 32273 chrX 943 78207 chrX 93 4529 chrX 351 55760 chrX 330 48821 chrX 417 73366 chrX 18 1769 chrX 204 83931 chrX 147 85116 chrX 756 70087 chrX 401 52244 chrX 384 59385 chrX 776 84082 chrX 405 33091 chrX 743 53418 chrX 15 94002 chrX 847 96756 chrX 712 94843 chrX 3 6437 chrX 495 33884 chrX 549 91884 chrX 63 56844 chrX 930 27687 chrX 405 8198 chrX 117 16252 chrX 771 52630 chrX 679 16207 chrX 108 45724 chrX 988 52440 chrX 783 73996 chrX 41 79888 chrX 672 89551 chrX 757 39210 chrX 830 76932 chrX 448 32999 chrX 94 99908 chrX 238 16069 chrX 565 17539 chrX 425 97529 chrX 247 54563 chrX 132 2025 chrX 61 81279 chrX 174 17210 chrX 268 16525 chrX 684 5822 chrX 894 73510 chrX 849 57521 chrX 614 61356 chrX 951 45458 chrX 368 40382 chrX 770 47107 chrX 398 1345 chrX 621 97045 chrX 179 4937 chrX 935 43625 chrX 590 7359 chrX 445 65696 chrX 879 62884 chrX 822 15645 chrX 782 51559 chrX 199 67933 chrX 233 5180 chrX 244 85135 chrX 656 20189 chrX 293 2828 chrX 595 7053 chrX 488 99865 chrX 74 11116 chrX 958 26285 chrX 158 89489 chrX 680 75556 chrX 961 13562 chrX 401 84490 chrX 746 23162 chrX 989 53859 chrX 731 19606 chrX 206 96794 chrX 238 45249 chrX 814 90326 chrX 645 11523 chrX 920 25013 chrX 173 41094 chrX 234 24977 chrX 519 19792 chrX 500 68265 chrX 86 18174 chrX 426 5132 chrX 306 83076 chrX 887 6184 chrX 51 87760 chrX 581 78961 chrX 65 78837 chrX 749 31156 chrX 237 56685 chrX 199 88528 chrX 673 12640 chrX 124 84788 chrX 528 36422 chrX 94 4947 chrX 551 60028 chrX 726 64499 chrX 775 16035 chrX 684 8940 chrX 980 58256 chrX 135 3353 chrX 449 72171 chrX 815 52386 chrX 504 57072 chrX 819 75099 chrX 130 2028 chrX 626 80969 chrX 138 75171 chrX 650 67405 chrX 109 74523 chrX 716 66812 chrX 338 44565 chrX 298 11757 chrX 594 98943 chrX 197 57717 chrX 556 33826 chrX 607 1219 chrX 49 42386 chrX 521 56009 chrX 989 35151 chrX 297 12219 chrX 360 92739 chrX 922 50849 chrX 674 57947 chrX 166 78507 chrX 316 88608 chrX 444 66025 chrX 325 74632 chrX 770 92779 chrX 726 97482 chrX 495 28778 chrX 300 10568 chrX 288 35308 chrX 526 81605 chrX 905 52417 chrX 152 20430 chrX 634 51936 chrX 126 55826 chrX 12 80082 chrX 129 18042 chrX 584 45246 chrX 62 2912 chrX 102 38829 chrX 771 88055 chrX 307 50122 chrX 840 81106 chrX 780 14848 chrX 905 7899 chrX 490 43630 chrX 880 40478 chrX 946 4260 chrX 598 58685 chrX 546 73081 chrX 137 55984 chrX 526 27287 chrX 737 11755 chrX 714 80681 chrX 138 81804 chrX 186 91212 chrX 689 50120 chrX 408 53399 chrX 296 19236 chrX 670 20902 chrX 259 16408 chrX 633 14640 chrX 557 58583 chrX 173 15798 chrX 161 72100 chrX 881 30781 chrX 277 41044 chrX 566 2114 chrX 517 28602 chrX 815 66468 chrX 97 308 chrX 566 79268 chrX 496 98017 chrX 316 79657 chrX 164 98918 chrX 995 43391 chrX 149 63096 chrX 564 71216 chrX 209 73935 chrX 862 37948 chrX 456 74894 chrX 669 74123 chrX 152 23800 chrX 750 67741 chrX 517 57035 chrX 326 61811 chrX 567 89892 chrX 401 6774 chrX 868 72751 chrX 857 4166 chrX 706 85993 chrX 457 85998 chrX 482 2591 chrX 561 69769 chrX 758 43229 chrX 62 21565 chrX 169 73450 chrX 949 33066 chrX 969 70929 chrX 991 49655 chrX 264 32018 chrX 101 83310 chrX 210 50549 chrX 895 8823 chrX 222 75519 chrX 112 92972 chrX 605 57547 chrX 784 9604 chrX 590 35186 chrX 780 35668 chrX 770 85092 chrX 563 94542 chrX 576 51925 chrX 260 54795 chrX 213 25418 chrX 32 47820 chrX 569 13920 chrX 309 78349 chrX 636 21216 chrX 859 86771 chrX 958 98163 chrX 787 57250 chrX 541 57716 chrX 652 13851 chrX 917 44228 chrX 480 69319 chrX 276 4755 chrX 628 85867 chrX 558 89473 chrX 397 77535 chrX 141 43116 chrX 249 71329 chrX 563 56487 chrX 491 20507 chrX 765 35855 chrX 59 72442 chrX 322 85025 chrX 288 86732 chrX 418 94547 chrX 996 34646 chrX 374 48106 chrX 24 65099 chrX 522 65831 chrX 503 8543 chrX 542 90631 chrX 851 69196 chrX 330 10435 chrX 394 89784 chrX 660 89207 chrX 94 42630 chrX 236 15573 chrX 149 56082 chrX 0 43766 chrX 423 42342 chrX 378 42399 chrX 755 76092 chrX 897 78956 chrX 404 42369 chrX 433 91161 chrX 500 98093 chrX 808 35993 chrX 659 14541 chrX 452 5816 chrX 32 11352 chrX 939 13620 chrX 538 18087 chrX 280 69056 chrX 734 28793 chrX 125 15985 chrX 699 51138 chrX 578 46125 chrX 257 47893 chrX 236 66427 chrX 896 67871 chrX 569 40178 chrX 645 38382 chrX 747 31255 chrX 516 20600 chrX 358 55251 chrX 314 30098 chrX 675 85937 chrX 473 96066 chrX 540 21357 chrX 236 66818 chrX 366 93997 chrX 170 94730 chrX 391 43190 chrX 421 63207 chrX 89 31889 chrX 297 66208 chrX 714 95045 chrX 36 46239 chrX 248 55517 chrX 662 61374 chrX 101 97794 chrX 904 78642 chrX 829 38660 chrX 733 37727 chrX 586 97570 chrX 35 95362 chrX 906 21504 chrX 898 30693 chrX 633 32718 chrX 925 73315 chrX 638 22982 chrX 383 35677 chrX 166 42116 chrX 814 42329 chrX 972 48758 chrX 22 7404 chrX 454 93178 chrX 851 29286 chrX 305 58757 chrX 654 89859 chrX 554 69560 chrX 845 46898 chrX 896 75316 chrX 758 53762 chrX 65 68495 chrX 253 70645 chrX 907 64602 chrX 56 7506 chrX 56 87241 chrX 489 3354 chrX 349 51541 chrX 102 80552 chrX 439 95807 chrX 88 74561 chrX 538 74854 chrX 636 9893 chrX 433 48643 chrX 553 33481 chrX 226 31386 chrX 859 29996 chrX 995 12322 chrX 995 91361 chrX 750 5966 chrX 978 81647 chrX 924 47706 chrX 835 28208 chrX 979 94761 chrX 78 41970 chrX 891 17601 chrX 163 43134 chrX 910 80953 chrX 522 34871 chrX 282 7822 chrX 672 51558 chrX 387 53598 chrX 800 39091 chrX 645 80198 chrX 286 39847 chrX 847 27321 chrX 202 77374 chrX 732 4497 chrX 45 71276 chrX 975 13344 chrX 131 86830 chrX 290 29780 chrX 296 20402 chrX 95 81994 chrX 544 38332 chrX 894 22628 chrX 886 29026 chrX 749 69447 chrX 664 40148 chrX 482 95571 chrX 790 33813 chrX 215 99491 chrX 101 94921 chrX 30 14770 chrX 660 1251 chrX 271 79448 chrX 872 57062 chrX 86 17047 chrX 762 18963 chrX 988 31741 chrX 559 88859 chrX 524 45188 chrX 164 27597 chrX 133 83005 chrX 669 62285 chrX 779 46742 chrX 946 100471 chrX 452 5286 chrX 943 49225 chrX 195 60593 chrX 488 47173 chrX 395 36559 chrX 28 48270 chrX 531 79703 chrX 664 52650 chrX 99 22532 chrX 402 62815 chrX 670 57396 chrX 898 81360 chrX 395 57159 chrX 420 17980 chrX 27 36745 chrX 170 48138 chrX 415 11846 chrX 962 62089 chrX 718 45843 chrX 78 11483 chrX 812 11501 chrX 596 35011 chrX 898 26989 chrX 864 100651 chrX 485 27173 chrX 622 16246 chrX 834 52882 chrX 960 23973 chrX 88 38253 chrX 405 11946 chrX 748 58408 chrX 595 17031 chrX 690 56451 chrX 775 41696 chrX 8 85385 chrX 523 82700 chrX 960 12935 chrX 165 86093 chrX 380 3375 chrX 857 87449 chrX 296 48212 chrX 22 13119 chrX 999 99302 chrX 361 9139 chrX 364 77050 chrX 203 11556 chrX 343 80172 chrX 277 3715 chrX 355 5708 chrX 443 36922 chrX 907 97593 chrX 186 86983 chrX 86 35336 chrX 727 47456 chrX 382 58824 chrX 333 68261 chrX 63 35601 chrX 810 7134 chrX 338 17476 chrX 151 70463 chrX 938 36360 chrX 816 28987 chrX 152 9606 chrX 316 51159 chrX 148 76116 chrX 873 6411 chrX 726 6705 chrX 923 82240 chrX 412 65474 chrX 280 79756 chrX 235 61603 chrX 474 30337 chrX 969 29400 chrX 361 31110 chrX 455 51745 chrX 10 39404 chrX 867 83593 chrX 675 2639 chrX 921 100096 chrX 528 7516 chrX 751 40881 chrX 125 47924 chrX 461 5324 chrX 291 87632 chrX 699 57862 chrX 668 94099 chrX 185 14407 chrX 232 15671 chrX 426 59909 chrX 461 88685 chrX 107 47357 chrX 276 97762 chrX 299 95483 chrX 994 23152 chrX 943 53201 chrX 291 69794 chrX 923 42598 chrX 173 38673 chrX 465 46885 chrX 258 16723 chrX 35 92693 chrX 98 22215 chrX 68 33259 chrX 375 49910 chrX 926 84671 chrX 377 3825 chrX 309 65687 chrX 9 60982 chrX 605 991 chrX 831 55754 chrX 526 12805 chrX 244 45278 chrX 539 42270 chrX 835 1328 chrX 881 10256 chrX 169 91905 chrX 20 26875 chrX 138 9054 chrX 600 52010 chrX 584 53306 chrX 351 96562 chrX 561 66712 chrX 615 57721 chrX 271 22424 chrX 574 10831 chrX 770 10907 chrX 225 1730 chrX 551 77043 chrX 432 39138 chrX 769 32157 chrX 480 94425 chrX 231 50348 chrX 208 37187 chrX 590 81438 chrX 883 18368 chrX 335 23880 chrX 136 89878 chrX 896 76182 chrX 468 17290 chrX 974 5315 chrX 270 74787 chrX 144 49761 chrX 760 70411 chrX 261 19519 chrX 83 3179 chrX 506 56946 chrX 970 74742 chrX 65 17907 chrX 107 65698 chrX 986 100127 chrX 830 33092 chrX 226 96998 chrX 220 12603 chrX 720 69574 chrX 292 69790 chrX 731 57017 chrX 440 88114 chrX 59 20096 chrX 573 32587 chrX 392 66076 chrX 351 90294 chrX 221 32373 chrX 637 29319 chrX 499 74966 chrX 942 49629 chrX 736 78086 chrX 809 97104 chrX 741 3696 chrX 86 46267 chrX 718 38603 chrX 156 45161 chrX 941 60636 chrX 326 402 chrX 797 90803 chrX 320 19350 chrX 556 67758 chrX 89 77904 chrX 993 73683 chrX 64 49414 chrX 471 1242 chrX 980 21747 chrX 781 79768 chrX 170 52414 chrX 819 26561 chrX 984 54737 chrX 636 14742 chrX 987 58787 chrX 738 32177 chrX 578 54114 chrX 214 90182 chrX 725 77861 chrX 571 82111 chrX 549 57074 chrX 542 61991 chrX 58 1446 chrX 622 4535 chrX 221 40564 chrX 829 40046 chrX 925 65770 chrX 649 91663 chrX 185 28773 chrX 51 17408 chrX 863 79786 chrX 487 44753 chrX 324 70567 chrX 342 5367 chrX 473 91878 chrX 865 3197 chrX 479 41274 chrX 637 54444 chrX 421 26424 chrX 577 64916 chrX 663 41285 chrX 35 58968 chrX 54 68571 chrX 499 24565 chrX 971 56039 chrX 414 83908 chrX 339 90560 chrX 277 66728 chrX 604 62600 chrX 714 8559 chrX 534 58576 chrX 101 1435 chrX 988 74948 chrX 551 41573 chrX 999 13861 chrX 53 66362 chrX 534 9452 chrX 252 59204 chrX 774 75965 chrX 830 75371 chrX 302 24744 chrX 580 64832 chrX 146 85943 chrX 307 75436 chrX 477 2656 chrX 829 2025 chrX 602 93755 chrX 25 59085 chrX 671 58343 chrX 0 67076 chrX 705 6148 chrX 333 24352 chrX 143 58771 chrX 829 92626 chrX 338 66328 chrX 663 64743 chrX 904 25279 chrX 283 5379 chrX 101 59136 chrX 802 58769 chrX 612 63813 chrX 591 22028 chrX 563 62258 chrX 804 24272 chrX 193 80772 chrX 905 90807 chrX 860 24790 chrX 139 524 chrX 825 97718 chrX 921 17300 chrX 628 59151 chrX 804 54120 chrX 828 9619 chrX 584 93656 chrX 678 39317 chrX 510 29552 chrX 18 10222 chrX 504 58699 chrX 719 31696 chrX 816 92084 chrX 115 72324 chrX 811 98391 chrX 961 96054 chrX 979 79679 chrX 919 91069 chrX 950 55820 chrX 486 76025 chrX 81 31653 chrX 843 67443 chrX 246 52404 chrX 52 75736 chrX 812 7892 chrX 858 32538 chrX 652 58441 chrX 626 47567 chrX 490 74704 chrX 191 30419 chrX 717 16008 chrX 253 70014 chrX 939 18247 chrX 599 89670 chrX 721 9306 chrX 646 81013 chrX 401 49343 chrX 469 65270 chrX 11 52218 chrX 404 82705 chrX 592 26967 chrX 139 24704 chrX 841 77479 chrX 715 33938 chrX 508 91165 chrX 634 23282 chrX 59 88833 chrX 924 100865 chrX 60 52381 chrX 890 79153 chrX 609 54233 chrX 586 1650 chrX 25 5622 chrX 658 4325 chrX 578 6930 chrX 859 17952 chrX 327 100277 chrX 416 17309 chrX 765 13930 chrX 501 27942 chrX 38 13608 chrX 500 10272 chrX 23 42522 chrX 97 8525 chrX 948 99674 chrX 866 56593 chrX 523 45845 chrX 567 55484 chrX 509 23167 chrX 585 9310 chrX 290 44843 chrX 258 61996 chrX 445 67923 chrX 786 21878 chrX 806 29556 chrX 485 84951 chrX 423 99046 chrX 942 45608 chrX 411 4363 chrX 530 36474 chrX 26 39813 chrX 916 55945 chrX 851 49315 chrX 99 36129 chrX 711 69241 chrX 447 579 chrX 130 70705 chrX 618 58205 chrX 380 40883 chrX 786 19484 chrX 692 27905 chrX 31